PMID- 27181502
OWN - NLM
STAT- MEDLINE
DCOM- 20180927
LR  - 20180927
IS  - 1527-3792 (Electronic)
IS  - 0022-5347 (Linking)
VI  - 196
IP  - 5
DP  - 2016 Nov
TI  - Probabilities of Dilating Vesicoureteral Reflux in Children with First Time
      Simple Febrile Urinary Tract Infection, and Normal Renal and Bladder Ultrasound.
PG  - 1541-1545
LID - S0022-5347(16)30404-9 [pii]
LID - 10.1016/j.juro.2016.05.038 [doi]
AB  - PURPOSE: We evaluated risk factors and assessed predicted probabilities for grade
      III or higher vesicoureteral reflux (dilating reflux) in children with a first
      simple febrile urinary tract infection and normal renal and bladder ultrasound.
      MATERIALS AND METHODS: Data for 167 children 2 to 72 months old with a first
      febrile urinary tract infection and normal ultrasound were compared between those
      who had dilating vesicoureteral reflux (12 patients, 7.2%) and those who did not.
      Exclusion criteria consisted of history of prenatal hydronephrosis or familial
      reflux and complicated urinary tract infection. The logistic regression model was
      used to identify independent variables associated with dilating reflux. Predicted
      probabilities for dilating reflux were assessed. RESULTS: Patient age and
      prevalence of nonEscherichia coli bacteria were greater in children who had
      dilating reflux compared to those who did not (p = 0.02 and p = 0.004,
      respectively). Gender distribution was similar between the 2 groups (p = 0.08).
      In multivariate analysis older age and nonE. coli bacteria independently
      predicted dilating reflux, with odds ratios of 1.04 (95% CI 1.01-1.07, p = 0.02) 
      and 3.76 (95% CI 1.05-13.39, p = 0.04), respectively. The impact of nonE. coli
      bacteria on predicted probabilities of dilating reflux increased with patient
      age. CONCLUSIONS: We support the concept of selective voiding cystourethrogram in
      children with a first simple febrile urinary tract infection and normal
      ultrasound. Voiding cystourethrogram should be considered in children with late
      onset urinary tract infection due to nonE. coli bacteria since they are at risk
      for dilating reflux even if the ultrasound is normal.
CI  - Copyright (c) 2016 American Urological Association Education and Research, Inc.
      Published by Elsevier Inc. All rights reserved.
FAU - Rianthavorn, Pornpimol
AU  - Rianthavorn P
AD  - Division of Nephrology, Department of Pediatrics, Faculty of Medicine,
      Chulalongkorn University, Bangkok, Thailand. Electronic address:
      pornpimol.r@chula.ac.th.
FAU - Tangngamsakul, Onjira
AU  - Tangngamsakul O
AD  - Division of Nephrology, Department of Pediatrics, Faculty of Medicine,
      Chulalongkorn University, Bangkok, Thailand.
LA  - eng
PT  - Journal Article
DEP - 20160512
PL  - United States
TA  - J Urol
JT  - The Journal of urology
JID - 0376374
SB  - AIM
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Dilatation, Pathologic
MH  - Female
MH  - Fever/complications
MH  - Humans
MH  - Infant
MH  - Kidney/diagnostic imaging
MH  - Male
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Ultrasonography
MH  - Urinary Bladder/diagnostic imaging
MH  - Urinary Tract Infections/*complications
MH  - Vesico-Ureteral Reflux/*complications/*pathology
OTO - NOTNLM
OT  - *ultrasonography
OT  - *urinary tract infections
OT  - *urination
OT  - *vesico-ureteral reflux
EDAT- 2016/10/19 06:00
MHDA- 2018/09/28 06:00
CRDT- 2016/05/17 06:00
PHST- 2016/05/08 00:00 [accepted]
PHST- 2016/10/19 06:00 [pubmed]
PHST- 2018/09/28 06:00 [medline]
PHST- 2016/05/17 06:00 [entrez]
AID - S0022-5347(16)30404-9 [pii]
AID - 10.1016/j.juro.2016.05.038 [doi]
PST - ppublish
SO  - J Urol. 2016 Nov;196(5):1541-1545. doi: 10.1016/j.juro.2016.05.038. Epub 2016 May
      12.