PMID- 26630534
OWN - NLM
STAT- MEDLINE
DCOM- 20160624
LR  - 20151214
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 10
IP  - 12
DP  - 2015
TI  - Low Osteoporosis Treatment Initiation Rate in Women after Distal Forearm or
      Proximal Humerus Fracture: A Healthcare Database Nested Cohort Study.
PG  - e0143842
LID - 10.1371/journal.pone.0143842 [doi]
AB  - Treatment initiation rates following fragility fractures have often been reported
      to be low and in recent years numerous programs have been implemented worldwide
      to increase them. This study aimed at describing osteoporosis (OP) treatment
      initiation in a representative sample of women who were hospitalized for a distal
      forearm fracture (DFF) or proximal humerus fracture (PHF) in 2009-2011 in France.
      The data source was a nationwide sample of 600,000 individuals, extracted from
      the French National Insurance Healthcare System database. All women aged 50 years
      and older who were hospitalized for a DFF or PHF between 2009 and 2011 and who
      had not received any OP treatment in the preceding 12 months were included in a
      retrospective cohort study. OP treatments initiated during the year following the
      fracture were analyzed. From 2009 to 2011, 729 women were hospitalized for a DFF 
      or a PHF and 284 were on OP treatment at the time of the fracture occurrence.
      Among the 445 women who had no prevalent OP treatment, 131 (29.4%) received
      supplementation treatment only (vitamin D and/or calcium) and 42 (9.4%) received 
      a pharmacologic OP treatment in the year following their fracture.
      Pharmacological OP treatments included bisphosphonates (n = 21), strontium
      ranelate (n = 14), hormone replacement therapy (n = 4), or raloxifene (n = 3).
      General practitioners prescribed 75% of initial OP treatments. Despite the
      guidelines published in 2006 and the numerous initiatives to promote
      post-fracture OP treatment, OP treatment initiation rate in women who were
      hospitalized for a fragility fracture remained low in 2009-2011 in France.
FAU - Viprey, Marie
AU  - Viprey M
AD  - Pole Information Medicale, Evaluation, Recherche, Hospices Civils de Lyon, Lyon, 
      France.
AD  - Faculte de Medecine Lyon Est, Universite Claude Bernard Lyon 1, Lyon, France.
FAU - Caillet, Pascal
AU  - Caillet P
AD  - Pole Information Medicale, Evaluation, Recherche, Hospices Civils de Lyon, Lyon, 
      France.
AD  - Faculte de Medecine Lyon Est, Universite Claude Bernard Lyon 1, Lyon, France.
AD  - Departement d'epidemiologie, hygiene hospitaliere et sante publique, Centre
      Hospitalier Universitaire d'Amiens, Amiens, France.
AD  - INSERM U1033, Lyon, France.
FAU - Canat, Guillaume
AU  - Canat G
AD  - Pole Information Medicale, Evaluation, Recherche, Hospices Civils de Lyon, Lyon, 
      France.
AD  - Departement de l'Information Medicale, Groupe Hospitalier Sud Reunion, Centre
      Hospitalier Universitaire de la Reunion, Saint Pierre, France.
FAU - Jaglal, Susan
AU  - Jaglal S
AD  - Department of Physical Therapy, Toronto Rehabilitation Institute-UHN Chair,
      University of Toronto, Toronto, Canada.
FAU - Haesebaert, Julie
AU  - Haesebaert J
AD  - Pole Information Medicale, Evaluation, Recherche, Hospices Civils de Lyon, Lyon, 
      France.
FAU - Chapurlat, Roland
AU  - Chapurlat R
AD  - Faculte de Medecine Lyon Est, Universite Claude Bernard Lyon 1, Lyon, France.
AD  - INSERM U1033, Lyon, France.
AD  - Service de Rhumatologie et de Pathologie Osseuse, Groupement Hospitalier Edouard 
      Herriot, Hospices Civils de Lyon, Lyon, France.
FAU - Schott, Anne-Marie
AU  - Schott AM
AD  - Pole Information Medicale, Evaluation, Recherche, Hospices Civils de Lyon, Lyon, 
      France.
AD  - Faculte de Medecine Lyon Est, Universite Claude Bernard Lyon 1, Lyon, France.
AD  - INSERM U1033, Lyon, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20151202
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - *Database Management Systems
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Osteoporosis/complications/*therapy
MH  - Radius Fractures/complications/*therapy
MH  - Shoulder Fractures/complications/*therapy
PMC - PMC4667917
EDAT- 2015/12/03 06:00
MHDA- 2016/06/25 06:00
CRDT- 2015/12/03 06:00
PHST- 2015/05/11 00:00 [received]
PHST- 2015/11/10 00:00 [accepted]
PHST- 2015/12/03 06:00 [entrez]
PHST- 2015/12/03 06:00 [pubmed]
PHST- 2016/06/25 06:00 [medline]
AID - 10.1371/journal.pone.0143842 [doi]
AID - PONE-D-15-19905 [pii]
PST - epublish
SO  - PLoS One. 2015 Dec 2;10(12):e0143842. doi: 10.1371/journal.pone.0143842.
      eCollection 2015.