PMID- 26341891
OWN - NLM
STAT- MEDLINE
DCOM- 20160824
LR  - 20160215
IS  - 1522-9645 (Electronic)
IS  - 0195-668X (Linking)
VI  - 37
IP  - 7
DP  - 2016 Feb 14
TI  - Sudden unexpected death in children with congenital heart defects.
PG  - 621-6
LID - 10.1093/eurheartj/ehv478 [doi]
AB  - AIMS: Congenital heart defects (CHDs) are the most common birth defects and are
      an important cause of death in children. The fear of sudden unexpected death has 
      led to restrictions of physical activity and competitive sports. The aim of the
      present study was to investigate the rate of sudden unexpected deaths unrelated
      to surgery in children 2-18 years old with CHDs and, secondarily, to determine
      whether these deaths were related to cardiac disease, comorbidity, or physical
      activity. METHODS AND RESULTS: To identify children with CHDs and to determine
      the number of deaths, data concerning all 9 43 871 live births in Norway in
      1994-2009 were retrieved from the Medical Birth Registry of Norway, the
      Cardiovascular Disease in Norway project, the Oslo University Hospital's Clinical
      Registry for Congenital Heart Defects and the Norwegian Cause of Death Registry. 
      Survivors were followed through 2012, and information for the deceased children
      was retrieved from medical records at Norwegian hospitals. Among 11 272 children 
      with CHDs, we identified 19 (0.2%) children 2-18 years old who experienced sudden
      unexpected deaths unrelated to cardiac surgery. A cardiac cause of death was
      identified in seven of these cases. None of the children died during physical
      activity, whereas two children survived cardiac arrest during sports. CONCLUSION:
      Sudden unexpected death was infrequent among children with CHDs who survived 2
      years of age. Comorbidity was common among the children who died. This study
      indicates that sudden unexpected death in children with CHDs rarely occurs during
      physical activity.
CI  - Published on behalf of the European Society of Cardiology. All rights reserved.
      (c) The Author 2015. For permissions please email: journals.permissions@oup.com.
FAU - Jortveit, Jarle
AU  - Jortveit J
AD  - Department of Cardiology, Sorlandet Hospital, PO Box 783, Stoa, 4809 Arendal,
      Norway Institute of Clinical Medicine, University of Oslo, Oslo, Norway
      jarle.jortveit@sshf.no.
FAU - Eskedal, Leif
AU  - Eskedal L
AD  - Research Department, Sorlandet Hospital, Kristiansand, Norway.
FAU - Hirth, Asle
AU  - Hirth A
AD  - Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
FAU - Fomina, Tatiana
AU  - Fomina T
AD  - Department of Global Public Health and Primary Care, University of Bergen,
      Bergen, Norway.
FAU - Dohlen, Gaute
AU  - Dohlen G
AD  - Women's and Children's Department, Oslo University Hospital, Oslo, Norway.
FAU - Hagemo, Petter
AU  - Hagemo P
AD  - Women's and Children's Department, Oslo University Hospital, Oslo, Norway.
FAU - Tell, Grethe S
AU  - Tell GS
AD  - Department of Global Public Health and Primary Care, University of Bergen,
      Bergen, Norway Division of Epidemiology, Norwegian Institute of Public Health,
      Bergen, Norway.
FAU - Birkeland, Sigurd
AU  - Birkeland S
AD  - Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway.
FAU - Oyen, Nina
AU  - Oyen N
AD  - Department of Global Public Health and Primary Care, University of Bergen,
      Bergen, Norway Center for Medical Genetics and Molecular Medicine, Haukeland
      University Hospital, Bergen, Norway.
FAU - Holmstrom, Henrik
AU  - Holmstrom H
AD  - Institute of Clinical Medicine, University of Oslo, Oslo, Norway Women's and
      Children's Department, Oslo University Hospital, Oslo, Norway.
LA  - eng
PT  - Comment
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150904
PL  - England
TA  - Eur Heart J
JT  - European heart journal
JID - 8006263
SB  - IM
CON - Eur Heart J. 2016 Feb 14;37(7):627-9. PMID: 26491107
MH  - Cardiac Surgical Procedures
MH  - *Cause of Death
MH  - Child
MH  - Death, Sudden
MH  - *Heart Defects, Congenital
MH  - Humans
MH  - Registries
OTO - NOTNLM
OT  - Cardiology
OT  - Congenital heart defect
OT  - Mortality
OT  - Sport
OT  - Sudden unexpected death
EDAT- 2015/09/06 06:00
MHDA- 2016/08/25 06:00
CRDT- 2015/09/06 06:00
PHST- 2015/03/23 00:00 [received]
PHST- 2015/08/24 00:00 [accepted]
PHST- 2015/09/06 06:00 [entrez]
PHST- 2015/09/06 06:00 [pubmed]
PHST- 2016/08/25 06:00 [medline]
AID - ehv478 [pii]
AID - 10.1093/eurheartj/ehv478 [doi]
PST - ppublish
SO  - Eur Heart J. 2016 Feb 14;37(7):621-6. doi: 10.1093/eurheartj/ehv478. Epub 2015
      Sep 4.