PMID- 26274629
OWN - NLM
STAT- MEDLINE
DCOM- 20160609
LR  - 20150916
IS  - 1531-8257 (Electronic)
IS  - 0885-3185 (Linking)
VI  - 30
IP  - 11
DP  - 2015 Sep 15
TI  - Advances in functional neurosurgery for Parkinson's disease.
PG  - 1461-70
LID - 10.1002/mds.26338 [doi]
AB  - Functional neurosurgery for Parkinson's disease has become a mainstream concept
      with DBS as the prime modality. This article reviews the latest and, in the eyes 
      of the authors, the most important developments in DBS, lesioning and gene
      therapy. In DBS, emerging advances have focused on the timing of surgery relative
      to disease duration and severity, and new targets, technologies, and equipment.
      For lesions, new ultrasound techniques are emerging based on successes in other
      movement disorders. Gene and cellular therapies, including stem cells, remain
      only in the research realm.
CI  - (c) 2015 International Parkinson and Movement Disorder Society.
FAU - Metman, Leo Verhagen
AU  - Metman LV
AD  - Department of Neurological Sciences, Rush University, Chicago, Illinois, USA.
FAU - Slavin, Konstantin V
AU  - Slavin KV
AD  - Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois,
      USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20150814
PL  - United States
TA  - Mov Disord
JT  - Movement disorders : official journal of the Movement Disorder Society
JID - 8610688
SB  - IM
MH  - Brain/*physiology
MH  - Deep Brain Stimulation/*methods
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Neurosurgical Procedures/*methods
MH  - Parkinson Disease/*therapy
MH  - Tomography, X-Ray Computed
OTO - NOTNLM
OT  - DBS
OT  - Parkinson
OT  - closed loop
OT  - current steering
OT  - focused ultrasound
OT  - frameless
OT  - functional neurosurgery
OT  - gene therapy
OT  - intra-operative CT
OT  - intra-operative MRI
OT  - surgery
EDAT- 2015/08/15 06:00
MHDA- 2016/06/10 06:00
CRDT- 2015/08/15 06:00
PHST- 2015/06/15 00:00 [received]
PHST- 2015/06/23 00:00 [accepted]
PHST- 2015/08/15 06:00 [entrez]
PHST- 2015/08/15 06:00 [pubmed]
PHST- 2016/06/10 06:00 [medline]
AID - 10.1002/mds.26338 [doi]
PST - ppublish
SO  - Mov Disord. 2015 Sep 15;30(11):1461-70. doi: 10.1002/mds.26338. Epub 2015 Aug 14.