PMID- 26046556
OWN - NLM
STAT- MEDLINE
DCOM- 20160104
LR  - 20170220
IS  - 1600-0404 (Electronic)
IS  - 0001-6314 (Linking)
VI  - 132
IP  - 199
DP  - 2015
TI  - Time trends in the incidence and prevalence of multiple sclerosis in Norway
      during eight decades.
PG  - 29-36
LID - 10.1111/ane.12428 [doi]
AB  - Norway has been subjected to numerous epidemiological investigations on the
      prevalence and incidence of multiple sclerosis (MS), dating back to 1935. The
      objective of this study was to review the studies on the prevalence and incidence
      of MS in Norway, provide an update on the prevalence of MS in Norway, and
      describe the time trends in the prevalence and incidence of MS in relation to
      risk factors, case ascertainment, and data. We performed a systematic search on
      PubMed and MEDLINE up to November 2014 using the search string 'multiple
      sclerosis prevalence in Norway' or 'multiple sclerosis incidence in Norway'. In
      addition, we scrutinized the reference lists of the publications identified for
      relevant citations. We retrieved data on the distribution of MS in Norway on
      December 31, 2013 from the Norwegian Multiple Sclerosis Registry and Biobank and 
      the Norwegian Patient Registry. We identified 29 articles. From 1961 to 2014, the
      reported prevalence of MS increased from 20 to 203 per 100,000 inhabitants, and
      the incidence increased from 1.9 to 8.0 per 100,000. The nationwide crude
      prevalence in Norway, based on the Norwegian Patient Registry, was 208 per
      100,000 on December 31, 2013. The reported prevalence of MS in Norway has
      increased 10-fold, with several possible causes. During eight decades,
      neurological health services have generally become more accessible to the
      population, and transforming diagnostic criteria has made the diagnosis of MS
      more precise and valid. There have also been changes in lifestyle behavior and
      known risk factors, such as vitamin D and smoking, that might have contributed to
      the increased incidence of MS. A possible role of increased survival in MS needs 
      to be examined further.
CI  - (c) 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Grytten, N
AU  - Grytten N
AD  - KG Jebsen MS Research Centre, Department of Clinical Medicine, University of
      Bergen, Bergen, Norway.
AD  - Norwegian Multiple Sclerosis Competence Centre, Department of Neurology,
      Haukeland University Hospital, Bergen, Norway.
FAU - Torkildsen, O
AU  - Torkildsen O
AD  - KG Jebsen MS Research Centre, Department of Clinical Medicine, University of
      Bergen, Bergen, Norway.
AD  - Norwegian Multiple Sclerosis Competence Centre, Department of Neurology,
      Haukeland University Hospital, Bergen, Norway.
FAU - Myhr, K-M
AU  - Myhr KM
AD  - KG Jebsen MS Research Centre, Department of Clinical Medicine, University of
      Bergen, Bergen, Norway.
AD  - Norwegian Multiple Sclerosis Registry and Biobank, Department of Neurology,
      Haukeland University Hospital, Bergen, Norway.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PL  - Denmark
TA  - Acta Neurol Scand
JT  - Acta neurologica Scandinavica
JID - 0370336
SB  - IM
CIN - Acta Neurol Scand. 2015 Nov;132(5):368-9. PMID: 26369381
CIN - Acta Neurol Scand. 2015 Nov;132(5):364-7. PMID: 26423981
MH  - Biological Specimen Banks
MH  - Emigration and Immigration
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Multiple Sclerosis/*epidemiology
MH  - Norway/epidemiology
MH  - Prevalence
MH  - Sex Ratio
PMC - PMC4657466
OTO - NOTNLM
OT  - environmental risk factors
OT  - incidence
OT  - multiple sclerosis
OT  - prevalence
OT  - time trends
EDAT- 2015/06/06 06:00
MHDA- 2016/01/05 06:00
CRDT- 2015/06/06 06:00
PHST- 2015/04/10 00:00 [accepted]
PHST- 2015/06/06 06:00 [entrez]
PHST- 2015/06/06 06:00 [pubmed]
PHST- 2016/01/05 06:00 [medline]
AID - 10.1111/ane.12428 [doi]
PST - ppublish
SO  - Acta Neurol Scand. 2015;132(199):29-36. doi: 10.1111/ane.12428.