PMID- 25635882
OWN - NLM
STAT- MEDLINE
DCOM- 20151006
LR  - 20180813
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 10
IP  - 1
DP  - 2015
TI  - Serum levels of 25-hydroxyvitamin D and functional outcome among postmenopausal
      women with hip fracture.
PG  - e0116375
LID - 10.1371/journal.pone.0116375 [doi]
AB  - OBJECTIVE: The main objective of the current study was to assess the distribution
      and its prognostic value of serum 25-hydroxyvitamin D (25[OH] D) levels assessed 
      at admission in Chinese postmenopausal women with hip fracture. METHODS: From
      January 1, 2012 to December 31, 2013, all postmenopausal women with first-ever
      hip fracture were recruited to participate in the study. Serum 25[OH] D levels
      were measured at admission. The functional evaluation at the time of discharge
      was performed by the Barthel Index (BI). The prognostic value of 25[OH] D to
      predict the functional outcome within discharge was analyzed by logistic
      regression analysis, after adjusting for the possible confounders. RESULTS: In
      our study, 261 patients were included and assessed. In the 76 patients with an
      unfavorable functional outcome, serum 25(OH) D levels were lower compared with
      those in patients with a favorable outcome [11.8(IQR, 9.9-16.1) ng/ml; 16.8(IQR, 
      13.6-21.4) ng/ml, respectively; P<0.0001]. In multivariate analysis, there was an
      increased risk of unfavorable outcome associated with serum 25(OH) D levels </=
      20 ng/ml (OR 5.24, 95%CI: 3.11-8.15; P<0.0001) after adjusting for possible
      confounders. CONCLUSIONS: Our data support an association between serum 25[OH] D 
      levels and prognosis in Chinese postmenopausal women with hip fracture.
FAU - Liu, Lan-Mei
AU  - Liu LM
AD  - Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province,
      People's Republic of China.
FAU - Wang, Shuai-Hua
AU  - Wang SH
AD  - Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province,
      People's Republic of China.
FAU - Fu, Chuan-Sheng
AU  - Fu CS
AD  - Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province,
      People's Republic of China.
FAU - Han, Xiang-Zhen
AU  - Han XZ
AD  - Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province,
      People's Republic of China.
FAU - Wei, Bao-Fu
AU  - Wei BF
AD  - Hand and Foot Surgery Department, Shandong Provincial Hospital, Jinan, Shandong
      province, People's Republic of China.
LA  - eng
SI  - figshare/10.6084/M9.FIGSHARE.1259245
PT  - Journal Article
DEP - 20150130
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
RN  - 1406-16-2 (Vitamin D)
RN  - A288AR3C9H (25-hydroxyvitamin D)
SB  - IM
MH  - Aged
MH  - Case-Control Studies
MH  - Female
MH  - Hip Fractures/*blood/therapy
MH  - Humans
MH  - Middle Aged
MH  - Osteoporosis, Postmenopausal/blood
MH  - Postmenopause
MH  - Prognosis
MH  - Recovery of Function
MH  - Treatment Outcome
MH  - Vitamin D/*analogs & derivatives/blood
PMC - PMC4312033
EDAT- 2015/01/31 06:00
MHDA- 2015/10/07 06:00
CRDT- 2015/01/31 06:00
PHST- 2014/09/13 00:00 [received]
PHST- 2014/12/04 00:00 [accepted]
PHST- 2015/01/31 06:00 [entrez]
PHST- 2015/01/31 06:00 [pubmed]
PHST- 2015/10/07 06:00 [medline]
AID - 10.1371/journal.pone.0116375 [doi]
AID - PONE-D-14-41268 [pii]
PST - epublish
SO  - PLoS One. 2015 Jan 30;10(1):e0116375. doi: 10.1371/journal.pone.0116375.
      eCollection 2015.