PMID- 25241203
OWN - NLM
STAT- MEDLINE
DCOM- 20150703
LR  - 20150406
IS  - 1872-8952 (Electronic)
IS  - 1388-2457 (Linking)
VI  - 126
IP  - 5
DP  - 2015 May
TI  - Heart rate variability evaluation of Emfit sleep mattress breathing categories in
      NREM sleep.
PG  - 967-74
LID - 10.1016/j.clinph.2014.08.012 [doi]
LID - S1388-2457(14)00468-4 [pii]
AB  - OBJECTIVE: Heart rate variability (HRV) analysis of obstructive sleep apnea
      patients reveals an increase in sympathetic activity. Sleep disordered breathing 
      (SDB) can be also assessed with sleep mattress sensors, as the Emfit sensor, by
      dividing the signal into different breathing categories. In addition to normal
      breathing (NB) and periodic apneas/hypopneas (POB), the sleep mattress unveils a 
      breathing category consisting of sustained partial obstruction (increased
      respiratory resistance, IRR). The aim of our study was to evaluate HRV during
      these three breathing categories in NREM sleep. METHODS: 53 patients with
      suspected SDB underwent an overnight polysomnography with an Emfit mattress. The 
      Emfit signal was scored in 3-min epochs according to the established rules. The
      NB, POB, and IRR epochs were combined to as long NB, POB and IRR periods as
      possible and HRV was calculated from at least 6-min epochs. RESULTS: The meanHR
      did not differ between the breathing categories. HRV parameters revealed an
      increase in sympathetic activity during POB. The mean LF/HF ratio was highest
      during POB (3.0) and lowest during IRR (1.3). During NB it was 1.7 (all p-values 
      0.001). Interestingly sympathetic activity decreased and parasympathetic activity
      increased during IRR as compared to NB (the mean HF power was 1113.8 ms(2) during
      IRR and 928.4 ms(2) during NB). CONCLUSIONS: The HRV findings during POB
      resembled HRV results of sleep apnea patients but during sustained prolonged
      partial obstruction a shift towards parasympathetic activity was achieved.
      SIGNIFICANCE: The findings encourage the use of sleep mattresses in SDB
      diagnostics. In addition the findings suggest that sustained partial obstruction 
      represents its own SDB entity.
CI  - Copyright (c) 2014 International Federation of Clinical Neurophysiology.
      Published by Elsevier Ireland Ltd. All rights reserved.
FAU - Tenhunen, Mirja
AU  - Tenhunen M
AD  - Department of Clinical Neurophysiology, Tampere University Hospital, Medical
      Imaging Centre and Hospital Pharmacy, Pirkanmaa Hospital District, Tampere,
      Finland; Department of Electronics and Communication Engineering and BioMediTech,
      Tampere University of Technology, Tampere, Finland. Electronic address:
      mirja.tenhunen@pshp.fi.
FAU - Hyttinen, Jari
AU  - Hyttinen J
AD  - Department of Electronics and Communication Engineering and BioMediTech, Tampere 
      University of Technology, Tampere, Finland.
FAU - Lipponen, Jukka A
AU  - Lipponen JA
AD  - Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
FAU - Virkkala, Jussi
AU  - Virkkala J
AD  - Department of Clinical Neurophysiology, Tampere University Hospital, Medical
      Imaging Centre and Hospital Pharmacy, Pirkanmaa Hospital District, Tampere,
      Finland.
FAU - Kuusimaki, Sonja
AU  - Kuusimaki S
AD  - Department of Clinical Physiology and Nuclear Medicine, Kuopio University
      Hospital, Kuopio, Finland.
FAU - Tarvainen, Mika P
AU  - Tarvainen MP
AD  - Department of Applied Physics, University of Eastern Finland, Kuopio, Finland;
      Department of Clinical Physiology and Nuclear Medicine, Kuopio University
      Hospital, Kuopio, Finland.
FAU - Karjalainen, Pasi A
AU  - Karjalainen PA
AD  - Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
FAU - Himanen, Sari-Leena
AU  - Himanen SL
AD  - Department of Clinical Neurophysiology, Tampere University Hospital, Medical
      Imaging Centre and Hospital Pharmacy, Pirkanmaa Hospital District, Tampere,
      Finland; School of Medicine, University of Tampere, Tampere, Finland.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140906
PL  - Netherlands
TA  - Clin Neurophysiol
JT  - Clinical neurophysiology : official journal of the International Federation of
      Clinical Neurophysiology
JID - 100883319
SB  - IM
MH  - Adult
MH  - Female
MH  - *Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Polysomnography
MH  - Sleep Apnea Syndromes/diagnosis/*physiopathology
MH  - *Sleep Stages
OTO - NOTNLM
OT  - Emfit sensor
OT  - Flow limitation
OT  - Heart rate variability
OT  - Sleep
OT  - Sleep mattress sensors
OT  - Sleep-disordered breathing
EDAT- 2014/09/23 06:00
MHDA- 2015/07/04 06:00
CRDT- 2014/09/22 06:00
PHST- 2013/11/28 00:00 [received]
PHST- 2014/08/18 00:00 [revised]
PHST- 2014/08/20 00:00 [accepted]
PHST- 2014/09/22 06:00 [entrez]
PHST- 2014/09/23 06:00 [pubmed]
PHST- 2015/07/04 06:00 [medline]
AID - S1388-2457(14)00468-4 [pii]
AID - 10.1016/j.clinph.2014.08.012 [doi]
PST - ppublish
SO  - Clin Neurophysiol. 2015 May;126(5):967-74. doi: 10.1016/j.clinph.2014.08.012.
      Epub 2014 Sep 6.