PMID- 30791131
OWN - NLM
STAT- In-Data-Review
LR  - 20190413
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
VI  - 36
IP  - 5
DP  - 2019 May
TI  - Decision aids for people with Type 2 diabetes mellitus: an effectiveness rapid
      review and meta-analysis.
PG  - 557-568
LID - 10.1111/dme.13939 [doi]
AB  - AIMS: To perform a rapid review and meta-analysis of randomized controlled trials
      (RCTs) evaluating patient decision aids (PtDAs) for people with Type 2 diabetes
      mellitus. METHODS: We searched Medline and the Cochrane Library for RCTs
      assessing PtDAs in people with Type 2 diabetes. PtDAs were defined as tools
      designed to help people engage in decision-making about healthcare options, such 
      as making treatment choices or setting therapeutic goals. The study selection
      process was facilitated by an automated screening tool to identify RCTs. We
      classified outcomes into seven domains and conducted meta-analyses using random
      effects models. RESULTS: We included a total of 15 studies, nine of which were
      cluster RCTs, that evaluated 10 PtDAs. Thirteen trials compared a PtDA with usual
      care or usual care plus educational material, whereas two RCTs compared
      individually tailored vs. non-tailored PtDAs. Meta-analyses showed a favourable
      effect of PtDAs compared with usual care in reducing decisional conflict
      [weighted mean difference (WMD) -4.66, 95% confidence interval (CI) -7.93 to
      -1.39] and in improving knowledge (WMD 20.46, 95% CI 9.13 to 3.77). Use of PtDAs 
      resulted in more active involvement in decision-making during the consultation,
      although no effect was evident in terms of glycaemic control or self-reported
      medication adherence. CONCLUSIONS: PtDAs for people with Type 2 diabetes can
      improve the quality of decision-making and increase knowledge transfer.
      Interpretation of our findings is attenuated due to limitations related to the
      rapid review approach, including searching only two databases and performing data
      extraction and risk of bias assessment by a single reviewer.
CI  - (c) 2019 Diabetes UK.
FAU - Karagiannis, T
AU  - Karagiannis T
AUID- ORCID: https://orcid.org/0000-0001-5242-0574
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
FAU - Andreadis, P
AU  - Andreadis P
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
FAU - Manolopoulos, A
AU  - Manolopoulos A
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
FAU - Malandris, K
AU  - Malandris K
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
FAU - Avgerinos, I
AU  - Avgerinos I
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
FAU - Karagianni, A
AU  - Karagianni A
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
FAU - Tsapas, A
AU  - Tsapas A
AD  - Clinical Research and Evidence-Based Medicine Unit, Aristotle University of
      Thessaloniki, Thessaloniki, Greece.
AD  - Harris Manchester College, University of Oxford, Oxford, UK.
LA  - eng
GR  - European Foundation for the Study of Diabetes (EFSD) award supported by
      AstraZeneca
PT  - Journal Article
PT  - Review
DEP - 20190312
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/19 00:00 [accepted]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
PHST- 2019/02/22 06:00 [entrez]
AID - 10.1111/dme.13939 [doi]
PST - ppublish
SO  - Diabet Med. 2019 May;36(5):557-568. doi: 10.1111/dme.13939. Epub 2019 Mar 12.

PMID- 30791130
OWN - NLM
STAT- Publisher
LR  - 20190313
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
DP  - 2019 Feb 21
TI  - Trends in cardiovascular management of people with diabetes by primary healthcare
      nurses in Auckland, New Zealand.
LID - 10.1111/dme.13940 [doi]
AB  - AIMS: The study aim was to re-examine current work practices and evaluate time
      trends in the cardiovascular management of people with diabetes consulted by
      primary healthcare nurses in New Zealand. METHODS: Primary healthcare nurses in
      the Auckland region were surveyed in 2006-2008 and 2016, with about one-third of 
      practice, home care and specialist nurses randomly selected to participate.
      Nurses completed a self-administered questionnaire about demographic and
      workplace details, and a telephone interview about clinical care provided for
      people with diabetes during nursing consultations. Information was collected on a
      representative sample of people with diabetes consulted on one randomly selected 
      work-day in the previous week. RESULTS: Of all people with diabetes consulted by 
      nurses, practice nurses consulted significantly more in 2016 (83%) compared with 
      60% in 2006-2008, whereas specialist nurse consultations decreased from 23% to 8%
      (P = 0.01). In 2016, in people with diabetes, BMI was higher, and total
      cholesterol lower, yet the proportions of those receiving lifestyle advice
      (dietary and activity) remained unchanged from 2006-2008 levels. Smoking
      prevalence in people with diabetes was unchanged between the two surveys,
      although more people were asked if they wished to stop in 2016 compared with
      2006-2008 (98% vs. 73%). In 2016, hours of nurses' diabetes education were
      associated with increased routine assessments of risk factors in people with
      diabetes and checking laboratory results. CONCLUSIONS: Practice nurses are
      undertaking an increasing proportion of diabetes consultations. Although BMI in
      people with diabetes is increasing, the proportion of nurses offering lifestyle
      advice remains unchanged. Increasing diabetes education could strengthen the
      management of people with diabetes by community nurses.
CI  - (c) 2019 Diabetes UK.
FAU - Daly, B M
AU  - Daly BM
AUID- ORCID: https://orcid.org/0000-0003-0329-4633
AD  - School of Nursing, University of Auckland, Auckland, New Zealand.
FAU - Arroll, B
AU  - Arroll B
AUID- ORCID: https://orcid.org/0000-0002-0451-9462
AD  - School of Population Health, University of Auckland, Auckland, New Zealand.
FAU - Scragg, R K R
AU  - Scragg RKR
AUID- ORCID: https://orcid.org/0000-0003-0013-2620
AD  - School of Population Health, University of Auckland, Auckland, New Zealand.
LA  - eng
GR  - Charitable trust of the Auckland Faculty of the Royal New Zealand College of
      General Practitioners
GR  - Novo Nordisk
GR  - New Zealand Ministry of Health
GR  - Faculty of Medical and Health Science, University of Auckland
PT  - Journal Article
DEP - 20190221
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/19 00:00 [accepted]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
PHST- 2019/02/22 06:00 [entrez]
AID - 10.1111/dme.13940 [doi]
PST - aheadofprint
SO  - Diabet Med. 2019 Feb 21. doi: 10.1111/dme.13940.

PMID- 30785642
OWN - NLM
STAT- Publisher
LR  - 20190403
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
DP  - 2019 Feb 20
TI  - Comment on the consensus report on the management of hyperglycaemia in Type 2
      diabetes by the American Diabetes Association and the European Association for
      the Study of Diabetes.
LID - 10.1111/dme.13934 [doi]
FAU - Skinner, T
AU  - Skinner T
AUID- ORCID: https://orcid.org/0000-0002-0018-6963
AD  - University of Copenhagen, Denmark.
AD  - Steno Diabetes Centre Copenhagen, Denmark.
FAU - Byrne, M
AU  - Byrne M
AD  - School of Psychology, National University of Ireland, Galway, Ireland.
FAU - Dickinson, J K
AU  - Dickinson JK
AD  - Diabetes Education and Management, Teachers College Columbia University, New
      York, NY, USA.
FAU - Fisher, L
AU  - Fisher L
AUID- ORCID: https://orcid.org/0000-0001-9481-9727
AD  - Family and Community Medicine, University of California San Francisco, San
      Francisco, LA, USA.
FAU - Funnell, M
AU  - Funnell M
AD  - University of Michigan Medical School, Ann Arbor, MI, USA.
FAU - Guzman, S
AU  - Guzman S
AD  - Behavioural Diabetes Institute, San Diego, CA, USA.
FAU - Hendrieckx, C
AU  - Hendrieckx C
AD  - Australian Centre for Behavioural Research in Diabetes, Melbourne, Victoria,
      Australia.
AD  - Deakin University, Australia.
FAU - Hermanns, N
AU  - Hermanns N
AUID- ORCID: https://orcid.org/0000-0002-9610-0975
AD  - Jazindiabetes, (Diabetes & Me), Slovenia.
FAU - Kanc, K
AU  - Kanc K
AD  - Forschungsinstitut Diabetes-Akademie, Bad Mergentheim, Germany.
FAU - Lloyd, C
AU  - Lloyd C
AUID- ORCID: https://orcid.org/0000-0002-8863-3069
AD  - Open University, Milton Keynes, UK.
FAU - Mocan, A
AU  - Mocan A
AD  - Emergency Clinical County Hospital, Cluj-Napoca, Romania.
FAU - Nouwen, A
AU  - Nouwen A
AUID- ORCID: https://orcid.org/0000-0002-0609-4082
AD  - Middlesex University, London, UK.
FAU - Pouwer, F
AU  - Pouwer F
AD  - University of Southern Denmark, Odense, Denmark.
FAU - Saleh-Stattin, N
AU  - Saleh-Stattin N
AD  - Academic Primary Health Care Centre, Stockholm, Sweden.
FAU - Snoek, F
AU  - Snoek F
AD  - Amsterdam UMC, Amsterdam, Netherlands.
FAU - Speight, J
AU  - Speight J
AUID- ORCID: https://orcid.org/0000-0002-1204-6896
AD  - Australian Centre for Behavioural Research in Diabetes, Melbourne, Victoria,
      Australia.
AD  - Deakin University, Australia.
FAU - Sturt, J
AU  - Sturt J
AD  - Florence Nightingale Faculty of Nursing and Midwifery, Kings College London,
      London, UK.
FAU - Vallis, M
AU  - Vallis M
AUID- ORCID: https://orcid.org/0000-0002-0165-5936
AD  - Dalhousie University, Halifax, Canada.
FAU - Wagner, J
AU  - Wagner J
AD  - Behavioral Sciences and Community Health, University of Connecticut Health
      Center, Farmington, CT, USA.
FAU - Willaing, I
AU  - Willaing I
AD  - Steno Diabetes Centre Copenhagen, Denmark.
FAU - Young-Hyman, D
AU  - Young-Hyman D
AD  - National Institute of Health, Bethesda, MD, USA.
FAU - Zoffmann, V
AU  - Zoffmann V
AD  - University of Copenhagen, Denmark.
LA  - eng
PT  - Letter
DEP - 20190220
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/21 06:00
MHDA- 2019/02/21 06:00
CRDT- 2019/02/21 06:00
PHST- 2019/02/21 06:00 [pubmed]
PHST- 2019/02/21 06:00 [medline]
PHST- 2019/02/21 06:00 [entrez]
AID - 10.1111/dme.13934 [doi]
PST - aheadofprint
SO  - Diabet Med. 2019 Feb 20. doi: 10.1111/dme.13934.

PMID- 30785640
OWN - NLM
STAT- Publisher
LR  - 20190313
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
DP  - 2019 Feb 20
TI  - Dietary intakes of women with Type 1 diabetes before and during pregnancy: a
      pre-specified secondary subgroup analysis among CONCEPTT participants.
LID - 10.1111/dme.13937 [doi]
AB  - AIM: To describe the dietary intakes of women with Type 1 diabetes before and
      during pregnancy. METHODS: This was a pre-specified subgroup analysis of CONCEPTT
      involving 63 women planning pregnancy and 93 pregnant women from 14 sites in
      England, Scotland and Ireland. Two hundred and forty-six 3-day food diaries (104 
      planning pregnancy, 142 pregnant) were matched to data source and food reference 
      codes, and analysed using dietary software. Participants were informed that food 
      diaries would be de-identified and used only for research purposes. RESULTS: Mean
      (sd) daily energy intake was 1588 (346) kcal and 1673 (384) kcal in women
      planning pregnancy and pregnant women respectively. Total carbohydrate intake was
      consistent with dietary guideline recommendations [180 (52) g planning pregnancy,
      198 (54) g pregnant], but non-recommended sources (e.g. sugars, preserves,
      confectionery, biscuits, cakes) contributed to 46% of total daily carbohydrate
      intake. Fat consumption exceeded guideline recommendations [70 (21) g planning
      pregnancy, 72 (21) g pregnant]. Fibre [15.5 (5.3) g planning pregnancy, 15.4
      (5.1) g pregnant], fruit and vegetable intakes [3.5 (2.2) and 3.1 (1.8)
      serves/day] were inadequate. Twelve women planning pregnancy (19%) and 24
      pregnant women (26%) did not meet micronutrient requirements. CONCLUSIONS: The
      diets of pregnant women from England, Scotland and Ireland are characterized by
      high fat, low fibre and poor-quality carbohydrate intakes. Fruit and vegetable
      consumption is inadequate, with one in four women at risk of micronutrient
      deficiencies. Further research is needed to optimize maternal nutrition for
      glycaemic control and for maternal and offspring health.
CI  - (c) 2019 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on
      behalf of Diabetes UK.
FAU - Neoh, S L
AU  - Neoh SL
AUID- ORCID: https://orcid.org/0000-0001-9387-7079
AD  - Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
FAU - Grisoni, J A
AU  - Grisoni JA
AD  - Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
FAU - Feig, D S
AU  - Feig DS
AUID- ORCID: https://orcid.org/0000-0001-8561-7584
AD  - Mount Sinai Hospital, Toronto, Canada.
AD  - Lunenfeld-Tanenbaum Research Institute, Toronto, Canada.
AD  - Department of Medicine, Division of Endocrinology, University of Toronto,
      Toronto, Canada.
FAU - Murphy, H R
AU  - Murphy HR
AUID- ORCID: https://orcid.org/0000-0001-6876-8727
AD  - Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
AD  - Department of Women and Children's Health, St Thomas' Hospital, London, UK.
AD  - Department of Medicine, University of East Anglia, Norwich, UK.
CN  - CONCEPTT Collaborative Group
LA  - eng
GR  - 80-2010-585/JDRF/United States
GR  - 17-2011-533/JDRF/United States
GR  - Gates Cambridge Scholarship
GR  - National Institute for Health Research
GR  - Tommy's charity
PT  - Journal Article
DEP - 20190220
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/21 06:00
MHDA- 2019/02/21 06:00
CRDT- 2019/02/21 06:00
PHST- 2019/02/18 00:00 [accepted]
PHST- 2019/02/21 06:00 [pubmed]
PHST- 2019/02/21 06:00 [medline]
PHST- 2019/02/21 06:00 [entrez]
AID - 10.1111/dme.13937 [doi]
PST - aheadofprint
SO  - Diabet Med. 2019 Feb 20. doi: 10.1111/dme.13937.

PMID- 30785639
OWN - NLM
STAT- In-Data-Review
LR  - 20190413
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
VI  - 36
IP  - 5
DP  - 2019 May
TI  - Systematic review of randomized controlled trials on antibiotic treatment for
      osteomyelitis in diabetes.
PG  - 546-556
LID - 10.1111/dme.13935 [doi]
AB  - AIM: To evaluate the efficacy of antibiotic therapy in osteomyelitis treatment
      among people with diabetes. METHODS: A systematic search of PubMed, EMBASE, AMED,
      Web of Science, the WHO trial registry, Cochrane library databases, and
      ClinicalTrials.gov, in addition to hand-searching, was undertaken in July 2018.
      Two reviewers independently extracted data. The studies' methodological quality
      was assessed using the modified Jadad scale. Descriptive analysis was performed. 
      RESULTS: Seven randomized controlled trials, with 393 participants in total, were
      included. The antibiotic regimens, treatments and follow-up durations varied
      among the trials. The total scores showed that the overall methodological quality
      of the seven studies was high, despite two studies showing some flaws in
      double-blinding and withdrawals/drop-outs. Of four studies comparing different
      antibiotic regimens, three implied a similar remission effect, while one implied 
      that ertapenem +/- vancomycin treatment showed a higher remission rate than
      tigecycline treatment; this conclusion was not robust because of low power and
      small sample size. In the other three studies, which included two different doses
      of ciprofloxacin, an antibiotics group and a conservative surgical group, and two
      durations of the same antibiotic strategy, no significant differences in
      remission were reported between the groups. No difference was observed in the
      analyses of microbiological outcomes, superinfections and relapse, except adverse
      events. CONCLUSIONS: There is no definitive evidence supporting the superiority
      of any particular antibiotic agent, dose, or administration duration in the
      treatment of osteomyelitis in diabetes. As the included studies had some flaws
      and limitations, further research is necessary.
CI  - (c) 2019 Diabetes UK.
FAU - Xing, K
AU  - Xing K
AD  - Department of Orthopaedic Oncology, Honghui Hospital, Xi'an Jiaotong University, 
      College of Medicine, Xi'an, Shaanxi, China.
FAU - Huang, G
AU  - Huang G
AD  - Department of Orthopaedic Oncology, Honghui Hospital, Xi'an Jiaotong University, 
      College of Medicine, Xi'an, Shaanxi, China.
FAU - Hua, S
AU  - Hua S
AD  - Department of Rheumatism and Immunity Branch, Xi an No. 5 Hospital, Xi'an,
      Shaanxi, China.
FAU - Xu, G
AU  - Xu G
AD  - Department of Neurosurgery, First Affiliated Hospital of Xi'an Medical
      University, Xi'an, Shaanxi, China.
FAU - Li, M
AU  - Li M
AUID- ORCID: https://orcid.org/0000-0002-7815-0565
AD  - Department of Paediatric Orthopedics, Honghui Hospital, Xi'an Jiaotong
      University, College of Medicine, Xi'an, Shaanxi, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190313
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/21 06:00
MHDA- 2019/02/21 06:00
CRDT- 2019/02/21 06:00
PHST- 2019/02/18 00:00 [accepted]
PHST- 2019/02/21 06:00 [pubmed]
PHST- 2019/02/21 06:00 [medline]
PHST- 2019/02/21 06:00 [entrez]
AID - 10.1111/dme.13935 [doi]
PST - ppublish
SO  - Diabet Med. 2019 May;36(5):546-556. doi: 10.1111/dme.13935. Epub 2019 Mar 13.

PMID- 30784109
OWN - NLM
STAT- Publisher
LR  - 20190313
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
DP  - 2019 Feb 19
TI  - Effect of age at menarche on microvascular complications among women with Type 1 
      diabetes.
LID - 10.1111/dme.13936 [doi]
AB  - AIM: To test the hypothesis that delayed menarche is associated with an increased
      microvascular complication risk among women with Type 1 diabetes. METHODS: We
      studied the female participants of an ongoing prospective study of
      childhood-onset Type 1 diabetes diagnosed during the period 1950-1980. Of 325
      women, we included data from 315 who had reached menarche by the study baseline
      (1986-1988) and who self-reported their age at menarche. Both cross-sectional and
      prospective analyses over the 25-year follow-up were used to assess the
      relationship of age at menarche with the prevalence, incidence and cumulative
      incidence of microvascular complications, comprising overt nephropathy,
      proliferative retinopathy and confirmed distal symmetric polyneuropathy. RESULTS:
      In cross-sectional analyses at baseline, the odds of overt nephropathy increased 
      1.24 times (P=0.02) with each annual increase in age at menarche, and 3.2 times
      (P=0.009) in those with delayed menarche compared with women with normal menarche
      onset, after adjustment. Similarly, the cumulative incidence of overt nephropathy
      increased 1.16 times (P=0.01) with each older year of menarche and women with
      delayed menarche were at twofold increased risk of overt nephropathy (hazard
      ratio 2.30, P=0.001) compared with women with normal menarche onset. However, age
      at menarche was not significantly associated with either proliferative
      retinopathy or confirmed distal symmetric polyneuropathy after adjusting for
      covariates. CONCLUSIONS: Age at menarche was significantly associated with the
      prevalence and cumulative incidence of overt nephropathy, but not with
      proliferative retinopathy or confirmed distal symmetric polyneuropathy in Type 1 
      diabetes. Women with delayed menarche may therefore be targeted for early
      screening and timely interventions to prevent the development of nephropathy.
CI  - (c) 2019 Diabetes UK.
FAU - Yi, Y
AU  - Yi Y
AD  - Department of Epidemiology, Graduate School of Public Health, University of
      Pittsburgh, Pittsburgh, PA, USA.
FAU - Denic-Roberts, H
AU  - Denic-Roberts H
AD  - Department of Epidemiology, Graduate School of Public Health, University of
      Pittsburgh, Pittsburgh, PA, USA.
FAU - Rubinstein, D
AU  - Rubinstein D
AD  - Department of Epidemiology, Graduate School of Public Health, University of
      Pittsburgh, Pittsburgh, PA, USA.
FAU - Orchard, T J
AU  - Orchard TJ
AD  - Department of Epidemiology, Graduate School of Public Health, University of
      Pittsburgh, Pittsburgh, PA, USA.
FAU - Costacou, T
AU  - Costacou T
AUID- ORCID: https://orcid.org/0000-0001-9303-3810
AD  - Department of Epidemiology, Graduate School of Public Health, University of
      Pittsburgh, Pittsburgh, PA, USA.
LA  - eng
GR  - Rossi Memorial Fund
GR  - DK34818/National Institute of Health
GR  - R01 DK034818/DK/NIDDK NIH HHS/United States
PT  - Journal Article
DEP - 20190219
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/21 06:00
MHDA- 2019/02/21 06:00
CRDT- 2019/02/21 06:00
PHST- 2019/02/18 00:00 [accepted]
PHST- 2019/02/21 06:00 [pubmed]
PHST- 2019/02/21 06:00 [medline]
PHST- 2019/02/21 06:00 [entrez]
AID - 10.1111/dme.13936 [doi]
PST - aheadofprint
SO  - Diabet Med. 2019 Feb 19. doi: 10.1111/dme.13936.

PMID- 30773681
OWN - NLM
STAT- In-Data-Review
LR  - 20190413
IS  - 1464-5491 (Electronic)
IS  - 0742-3071 (Linking)
VI  - 36
IP  - 5
DP  - 2019 May
TI  - A Type 1 diabetes technology pathway: consensus statement for the use of
      technology in Type 1 diabetes.
PG  - 531-538
LID - 10.1111/dme.13933 [doi]
AB  - In both adults and children with diabetes, technologies such as continuous
      subcutaneous insulin infusion using insulin pumps and continuous glucose
      monitoring can help improve diabetes control, reduce hypoglycaemia and improve
      quality of life. Access to these technologies in the UK is very variable. Some
      technologies are recommended by the National Institute for Health and Care
      Excellence, while others have not been appraised, and new technologies are
      emerging all the time. Additionally, different guidelines for adults and children
      further complicate access to diabetes technology in the transition from
      paediatric to adult care. Against this background, Diabetes UK and NHS England
      have brought together a multidisciplinary group of experts, including clinicians 
      and people with diabetes, to develop this consensus guideline, combining the
      different technologies into a common pathway to aid clinical and policy
      decision-making. We created a pathway that supports the incremental addition of
      technology as monotherapy and then dual therapy in the same way that we
      incrementally add in therapeutic agents to support people with Type 2 diabetes to
      achieve their personalized glycaemic targets. The pathway emphasizes the
      importance of structured education, specialist support and appropriate access to 
      psychological therapies, as essential pillars for optimized use of
      diabetes-related technology, and recommends the re-evaluation of its use when the
      individual is unable either to use the technology appropriately or to achieve the
      intended outcomes. This pathway is endorsed by UK-wide clinical and patient
      associations and we recommend that providers and commissioners use it to ensure
      the right individual with diabetes has access to the right technology in a timely
      way to help achieve better outcomes.
CI  - (c) 2019 Diabetes UK.
FAU - Choudhary, P
AU  - Choudhary P
AUID- ORCID: https://orcid.org/0000-0001-7635-4735
AD  - Diabetes Research Group, London, UK.
FAU - Campbell, F
AU  - Campbell F
AD  - St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
FAU - Joule, N
AU  - Joule N
AUID- ORCID: https://orcid.org/0000-0002-3827-8724
AD  - Diabetes, UK.
FAU - Kar, P
AU  - Kar P
AD  - Diabetes, NHS England, London, UK.
CN  - Diabetes UK
LA  - eng
PT  - Journal Article
DEP - 20190403
PL  - England
TA  - Diabet Med
JT  - Diabetic medicine : a journal of the British Diabetic Association
JID - 8500858
EDAT- 2019/02/19 06:00
MHDA- 2019/02/19 06:00
CRDT- 2019/02/19 06:00
PHST- 2019/02/14 00:00 [accepted]
PHST- 2019/02/19 06:00 [pubmed]
PHST- 2019/02/19 06:00 [medline]
PHST- 2019/02/19 06:00 [entrez]
AID - 10.1111/dme.13933 [doi]
PST - ppublish
SO  - Diabet Med. 2019 May;36(5):531-538. doi: 10.1111/dme.13933. Epub 2019 Apr 3.

PMID- 30787070
OWN - NLM
STAT- In-Data-Review
LR  - 20190311
IS  - 1939-327X (Electronic)
IS  - 0012-1797 (Linking)
VI  - 68
IP  - 3
DP  - 2019 Mar
TI  - Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin 
      Bierman Award Lecture.
PG  - 479-489
LID - 10.2337/dbi18-0036 [doi]
AB  - The past decade has witnessed an exponential increase in our ability to search
      the genome for genetic factors predisposing to cardiovascular disease (CVD) and
      in particular coronary heart disease (CHD). Identifying these genes could lead to
      the development of innovative strategies to prevent the cardiovascular
      complications of diabetes by allowing us to 1) create predictive algorithms for
      the identification of patients at especially high risk of CVD so that these
      individuals can undergo preventive interventions early in the natural history of 
      the disease; 2) discover as yet unknown disease pathways linking diabetes to
      atherosclerosis, which can be used as targets for the development of new
      CVD-preventing drugs specifically directed at subjects with diabetes; and 3)
      devise personalized programs increasing the cost-effectiveness of preventive
      interventions by tailoring them to the genetic background of each patient.
      Substantial progress has been made in each of these three areas as exemplified by
      the recent development of a CHD genetic risk score improving CHD prediction among
      subjects with type 2 diabetes, the discovery of a diabetes-specific CHD locus on 
      1q25 pointing to glutamine synthase (GLUL) and the gamma-glutamyl cycle as key
      regulators of CHD risk in diabetes, and the identification of two genetic loci
      allowing the selection of patients with type 2 diabetes who may especially
      benefit from intensive glycemic control. Translating these discoveries into
      clinical practice will not be without challenges, but the potential rewards, from
      the perspective of public health as well as that of persons with diabetes, make
      this goal worth pursuing.
CI  - (c) 2019 by the American Diabetes Association.
FAU - Doria, Alessandro
AU  - Doria A
AUID- ORCID: http://orcid.org/0000-0002-3830-4304
AD  - Research Division, Joslin Diabetes Center, Boston, MA
      alessandro.doria@joslin.harvard.edu.
AD  - Department of Medicine, Harvard Medical School, Boston, MA
      alessandro.doria@joslin.harvard.edu.
AD  - Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA
      alessandro.doria@joslin.harvard.edu.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Diabetes
JT  - Diabetes
JID - 0372763
PMC - PMC6385753
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PMCR- 2020/03/01 00:00
PHST- 2020/03/01 00:00 [pmc-release]
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 68/3/479 [pii]
AID - 10.2337/dbi18-0036 [doi]
PST - ppublish
SO  - Diabetes. 2019 Mar;68(3):479-489. doi: 10.2337/dbi18-0036.

PMID- 30787069
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1939-327X (Electronic)
IS  - 0012-1797 (Linking)
VI  - 68
IP  - 3
DP  - 2019 Mar
TI  - Targeting the Brain to Cure Type 2 Diabetes.
PG  - 476-478
LID - 10.2337/dbi18-0051 [doi]
FAU - Thorens, Bernard
AU  - Thorens B
AD  - Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland
      bernard.thorens@unil.ch.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Diabetes
JT  - Diabetes
JID - 0372763
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 68/3/476 [pii]
AID - 10.2337/dbi18-0051 [doi]
PST - ppublish
SO  - Diabetes. 2019 Mar;68(3):476-478. doi: 10.2337/dbi18-0051.

PMID- 30787068
OWN - NLM
STAT- In-Data-Review
LR  - 20190311
IS  - 1939-327X (Electronic)
IS  - 0012-1797 (Linking)
VI  - 68
IP  - 3
DP  - 2019 Mar
TI  - Linking Coronary Microvascular and Cardiac Diastolic Dysfunction in Diabetes: Are
      Women More Vulnerable?
PG  - 474-475
LID - 10.2337/dbi18-0053 [doi]
FAU - Bender, Shawn B
AU  - Bender SB
AUID- ORCID: http://orcid.org/0000-0003-4709-1387
AD  - Biomedical Sciences, University of Missouri, Columbia, MO benders@missouri.edu.
AD  - Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO
      benders@missouri.edu.
AD  - Research Service, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO
      benders@missouri.edu.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Diabetes
JT  - Diabetes
JID - 0372763
PMC - PMC6385759
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PMCR- 2020/03/01 00:00
PHST- 2020/03/01 00:00 [pmc-release]
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 68/3/474 [pii]
AID - 10.2337/dbi18-0053 [doi]
PST - ppublish
SO  - Diabetes. 2019 Mar;68(3):474-475. doi: 10.2337/dbi18-0053.

PMID- 30787066
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1939-327X (Electronic)
IS  - 0012-1797 (Linking)
VI  - 68
IP  - 3
DP  - 2019 Mar
TI  - In This Issue of Diabetes.
PG  - 469-470
LID - 10.2337/db19-ti03 [doi]
LA  - eng
PT  - Editorial
PL  - United States
TA  - Diabetes
JT  - Diabetes
JID - 0372763
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 68/3/469 [pii]
AID - 10.2337/db19-ti03 [doi]
PST - ppublish
SO  - Diabetes. 2019 Mar;68(3):469-470. doi: 10.2337/db19-ti03.

PMID- 30787065
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - Comment on Warren et al. Diabetes and Trajectories of Estimated Glomerular
      Filtration Rate: A Prospective Cohort Analysis of the Atherosclerosis Risk in
      Communities Study. Diabetes Care 2018;41:1646-1653.
PG  - e51-e52
LID - 10.2337/dc18-2288 [doi]
FAU - Kang, Ying-Xiu
AU  - Kang YX
AD  - Department of Endocrinology and Metabolism, The Second Affiliated Hospital,
      Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Lin, Xi-Ling
AU  - Lin XL
AD  - Department of Endocrinology and Metabolism, The Second Affiliated Hospital,
      Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Ding, Yue
AU  - Ding Y
AD  - Department of Endocrinology and Metabolism, The Second Affiliated Hospital,
      Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Pan, Xiao-Wen
AU  - Pan XW
AD  - Department of Endocrinology and Metabolism, The Second Affiliated Hospital,
      Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
FAU - He, Shu-Xia
AU  - He SX
AD  - Department of Endocrinology and Metabolism, The Second Affiliated Hospital,
      Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Shan, Peng-Fei
AU  - Shan PF
AUID- ORCID: http://orcid.org/0000-0002-6684-9395
AD  - Department of Endocrinology and Metabolism, The Second Affiliated Hospital,
      Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
      pengfeishan@zju.edu.cn.
LA  - eng
PT  - Letter
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/e51 [pii]
AID - 10.2337/dc18-2288 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):e51-e52. doi: 10.2337/dc18-2288.

PMID- 30787064
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - Response to Comment on Pongrac Barlovic et al. The Association of Severe Diabetic
      Retinopathy With Cardiovascular Outcomes in Long-standing Type 1 Diabetes: A
      Longitudinal Follow-up. Diabetes Care 2018;41:2487-2494.
PG  - e49-e50
LID - 10.2337/dci18-0058 [doi]
FAU - Pongrac Barlovic, Drazenka
AU  - Pongrac Barlovic D
AUID- ORCID: http://orcid.org/0000-0003-1975-0816
AD  - University Medical Center Ljubljana, Ljubljana, Slovenia.
AD  - Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
FAU - Harjutsalo, Valma
AU  - Harjutsalo V
AUID- ORCID: http://orcid.org/0000-0003-3568-9779
AD  - Folkhalsan Institute of Genetics, Folkhalsan Research Center, Helsinki, Finland.
AD  - Abdominal Center Nephrology, University of Helsinki and Helsinki University
      Central Hospital, Helsinki, Finland.
AD  - Diabetes and Obesity, Research Programs Unit, University of Helsinki, Helsinki,
      Finland.
AD  - The Chronic Disease Prevention Unit, National Institute for Health and Welfare,
      Helsinki, Finland.
FAU - Groop, Per-Henrik
AU  - Groop PH
AUID- ORCID: http://orcid.org/0000-0003-4055-6954
AD  - Folkhalsan Institute of Genetics, Folkhalsan Research Center, Helsinki, Finland
      per-henrik.groop@helsinki.fi.
AD  - Abdominal Center Nephrology, University of Helsinki and Helsinki University
      Central Hospital, Helsinki, Finland.
AD  - Diabetes and Obesity, Research Programs Unit, University of Helsinki, Helsinki,
      Finland.
AD  - Department of Diabetes, Central Clinical School, Monash University, Melbourne,
      Victoria, Australia.
LA  - eng
PT  - Letter
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/e49 [pii]
AID - 10.2337/dci18-0058 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):e49-e50. doi: 10.2337/dci18-0058.

PMID- 30787063
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - Comment on Pongrac Barlovic et al. The Association of Severe Diabetic Retinopathy
      With Cardiovascular Outcomes in Long-standing Type 1 Diabetes: A Longitudinal
      Follow-up. Diabetes Care 2018;41:2487-2494.
PG  - e48
LID - 10.2337/dc18-2202 [doi]
FAU - Camoin, Marion
AU  - Camoin M
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Delyfer, Marie-Noelle
AU  - Delyfer MN
AD  - Ophthalmology Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Korobelnik, Jean-Francois
AU  - Korobelnik JF
AD  - Ophthalmology Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Mohammedi, Kamel
AU  - Mohammedi K
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Blanco, Laurence
AU  - Blanco L
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Foussard, Ninon
AU  - Foussard N
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Poupon, Pauline
AU  - Poupon P
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Monlun, Marie
AU  - Monlun M
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Haissaguerre, Magalie
AU  - Haissaguerre M
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France.
FAU - Rigalleau, Vincent
AU  - Rigalleau V
AUID- ORCID: http://orcid.org/0000-0002-5175-6479
AD  - Endocrinology-Nutrition Department, Centre Hospitalier Universitaire de Bordeaux,
      Universite de Bordeaux, Bordeaux, France vincent.rigalleau@chu-bordeaux.fr.
LA  - eng
PT  - Letter
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/e48 [pii]
AID - 10.2337/dc18-2202 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):e48. doi: 10.2337/dc18-2202.

PMID- 30787061
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - Metformin for Gestational Diabetes Mellitus: Progeny, Perspective, and a
      Personalized Approach.
PG  - 396-399
LID - 10.2337/dci18-0055 [doi]
FAU - Barbour, Linda A
AU  - Barbour LA
AUID- ORCID: http://orcid.org/0000-0001-8656-3995
AD  - Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, and
      Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology,
      University of Colorado, Anschutz Medical Campus, Aurora, CO
      lynn.barbour@ucdenver.edu.
FAU - Feig, Denice S
AU  - Feig DS
AUID- ORCID: http://orcid.org/0000-0001-8561-7584
AD  - Department of Medicine, Division of Endocrinology and Metabolism, University of
      Toronto, Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/396 [pii]
AID - 10.2337/dci18-0055 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):396-399. doi: 10.2337/dci18-0055.

PMID- 30787059
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - Lois Jovanovic, MD, MACE: Pioneer in the Field of Diabetes and Pregnancy and
      Beyond.
PG  - 359-363
LID - 10.2337/dci18-0056 [doi]
FAU - Pettitt, David J
AU  - Pettitt DJ
AD  - Sansum Diabetes Research Institute, Santa Barbara, CA djpettittret@gmail.com.
FAU - Wollitzer, Alison Okada
AU  - Wollitzer AO
AD  - Sansum Diabetes Research Institute, Santa Barbara, CA.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/359 [pii]
AID - 10.2337/dci18-0056 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):359-363. doi: 10.2337/dci18-0056.

PMID- 30787058
OWN - NLM
STAT- In-Data-Review
LR  - 20190417
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - 2018 Health Care & Education Presidential Address: The American Diabetes
      Association in the Era of Health Care Transformation.
PG  - 352-358
LID - 10.2337/dci18-0051 [doi]
AB  - This address was delivered by Felicia Hill-Briggs, PhD, ABPP, President, Health
      Care & Education of the American Diabetes Association (ADA) at the ADA's 78th
      Scientific Sessions in Orlando, FL, on 23 June 2018. Diabetes has become a
      high-priority condition in the current era of health care transformation due to
      diabetes and prediabetes prevalence rates, suboptimal diabetes outcomes at the
      health care system and population levels, and high health care and public health 
      costs attributed to diabetes. Population health is the path forward for the ADA
      to facilitate diabetes health care and public health improvement nationally.
      Population health management initiatives underway at the ADA include Diabetes
      INSIDE for health care systems and a Mental Health Provider Training Program and 
      referral directory. Population health improvement initiatives include the
      prediabetes Risk Test Campaign, National Diabetes Prevention Program (DPP)
      dissemination in underserved states and populations, a DPP Express information
      technology platform, and a social determinants of health scientific review and
      recommendations. Dr. Hill-Briggs is a professor of medicine; physical medicine
      and rehabilitation; health, behavior, and society; and acute and chronic care at 
      Johns Hopkins University in Baltimore, MD. She is a core faculty member of the
      Welch Center for Prevention, Epidemiology & Clinical Research and colead of
      behavioral, social, and systems science for the Johns Hopkins Institute for
      Clinical and Translational Research. Dr. Hill-Briggs has been elected to the
      National Academy of Medicine of The National Academies of Science, Engineering,
      and Medicine and is the 2018 recipient of the Rachmiel Levine Medal for
      Leadership from the ADA.
CI  - (c) 2019 by the American Diabetes Association.
FAU - Hill-Briggs, Felicia
AU  - Hill-Briggs F
AD  - Department of Medicine, Division of General Internal Medicine, Johns Hopkins
      School of Medicine; Department of Health, Behavior, and Society, Johns Hopkins
      Bloomberg School of Public Health; Department of Acute and Chronic Care, Johns
      Hopkins School of Nursing; and Welch Center for Prevention, Epidemiology &
      Clinical Research, Baltimore, MD fbriggs3@jhmi.edu.
LA  - eng
GR  - UL1 TR001079/TR/NCATS NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
PMC - PMC6385700
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PMCR- 2020/03/01 00:00
PHST- 2020/03/01 00:00 [pmc-release]
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/352 [pii]
AID - 10.2337/dci18-0051 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):352-358. doi: 10.2337/dci18-0051.

PMID- 30787057
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - Therapeutic Inertia and the Legacy of Dysglycemia on the Microvascular and
      Macrovascular Complications of Diabetes.
PG  - 349-351
LID - 10.2337/dci18-0030 [doi]
FAU - Khunti, Kamlesh
AU  - Khunti K
AUID- ORCID: http://orcid.org/0000-0003-2343-7099
AD  - Diabetes Research Centre, University of Leicester, Leicester General Hospital,
      Leicester, U.K. kk22@le.ac.uk.
FAU - Seidu, Samuel
AU  - Seidu S
AD  - Diabetes Research Centre, University of Leicester, Leicester General Hospital,
      Leicester, U.K.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/349 [pii]
AID - 10.2337/dci18-0030 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):349-351. doi: 10.2337/dci18-0030.

PMID- 30787055
OWN - NLM
STAT- In-Data-Review
LR  - 20190221
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 3
DP  - 2019 Mar
TI  - In This Issue of Diabetes Care.
PG  - 343-344
LID - 10.2337/dc19-ti03 [doi]
LA  - eng
PT  - Editorial
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
EDAT- 2019/02/23 06:00
MHDA- 2019/02/23 06:00
CRDT- 2019/02/22 06:00
PHST- 2019/02/22 06:00 [entrez]
PHST- 2019/02/23 06:00 [pubmed]
PHST- 2019/02/23 06:00 [medline]
AID - 42/3/343 [pii]
AID - 10.2337/dc19-ti03 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Mar;42(3):343-344. doi: 10.2337/dc19-ti03.

PMID- 30327356
OWN - NLM
STAT- MEDLINE
DCOM- 20190218
LR  - 20190219
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Linking)
VI  - 41
IP  - 12
DP  - 2018 Dec
TI  - Prediabetes Is Associated With Structural Brain Abnormalities: The Maastricht
      Study.
PG  - 2535-2543
LID - 10.2337/dc18-1132 [doi]
AB  - OBJECTIVE: Structural brain abnormalities are key risk factors for brain
      diseases, such as dementia, stroke, and depression, in type 2 diabetes. It is
      unknown whether structural brain abnormalities already occur in prediabetes.
      Therefore, we investigated whether both prediabetes and type 2 diabetes are
      associated with lacunar infarcts (LIs), white matter hyperintensities (WMHs),
      cerebral microbleeds (CMBs), and brain atrophy. RESEARCH DESIGN AND METHODS: We
      used data from 2,228 participants (1,373 with normal glucose metabolism [NGM],
      347 with prediabetes, and 508 with type 2 diabetes (oversampled); mean age 59.2
      +/- 8.2 years; 48.3% women) of the Maastricht Study, a population-based cohort
      study. Diabetes status was determined with an oral glucose tolerance test. Brain 
      imaging was performed with 3 Tesla MRI. Results were analyzed with multivariable 
      logistic and linear regression analyses. RESULTS: Prediabetes and type 2 diabetes
      were associated with the presence of LIs (odds ratio 1.61 [95% CI 0.98-2.63] and 
      1.67 [1.04-2.68], respectively; P trend = 0.027), larger WMH (beta 0.07
      log10-transformed mL [log-mL] [95% CI 0.00-0.15] and 0.21 log-mL [0.14-0.28],
      respectively; P trend <0.001), and smaller white matter volumes (beta -4.0 mL
      [-7.3 to -0.6] and -7.2 mL [-10.4 to -4.0], respectively; P trend <0.001)
      compared with NGM. Prediabetes was not associated with gray matter volumes or the
      presence of CMBs. CONCLUSIONS: Prediabetes is associated with structural brain
      abnormalities, with further deterioration in type 2 diabetes. These results
      indicate that, in middle-aged populations, structural brain abnormalities already
      occur in prediabetes, which may suggest that the treatment of early dysglycemia
      may contribute to the prevention of brain diseases.
CI  - (c) 2018 by the American Diabetes Association.
FAU - van Agtmaal, Marnix J M
AU  - van Agtmaal MJM
AUID- ORCID: 0000-0002-0379-872X
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands marnix.van.agtmaal@mumc.nl.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - Houben, Alfons J H M
AU  - Houben AJHM
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - de Wit, Vera
AU  - de Wit V
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
FAU - Henry, Ronald M A
AU  - Henry RMA
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
AD  - Heart and Vascular Center, Maastricht University Medical Center+, Maastricht, the
      Netherlands.
FAU - Schaper, Nicolaas C
AU  - Schaper NC
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - Dagnelie, Pieter C
AU  - Dagnelie PC
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - Care and Public Health Research Institute, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - Department of Epidemiology, Maastricht University Medical Center+, Maastricht,
      the Netherlands.
FAU - van der Kallen, Carla J
AU  - van der Kallen CJ
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - Koster, Annemarie
AU  - Koster A
AD  - Care and Public Health Research Institute, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - Department of Social Medicine, Maastricht University Medical Center+, Maastricht,
      the Netherlands.
FAU - Sep, Simone J
AU  - Sep SJ
AD  - Care and Public Health Research Institute, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - Department of Rehabilitation Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
FAU - Kroon, Abraham A
AU  - Kroon AA
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - Jansen, Jacobus F A
AU  - Jansen JFA
AD  - Department of Radiology and Nuclear Medicine, Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - Hofman, Paul A
AU  - Hofman PA
AD  - Department of Radiology and Nuclear Medicine, Maastricht University Medical
      Center+, Maastricht, the Netherlands.
FAU - Backes, Walter H
AU  - Backes WH
AD  - Department of Radiology and Nuclear Medicine, Maastricht University Medical
      Center+, Maastricht, the Netherlands.
AD  - School for Mental Health and Neuroscience, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
FAU - Schram, Miranda T
AU  - Schram MT
AUID- ORCID: 0000-0001-8113-7604
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
AD  - Heart and Vascular Center, Maastricht University Medical Center+, Maastricht, the
      Netherlands.
FAU - Stehouwer, Coen D A
AU  - Stehouwer CDA
AD  - Department of Internal Medicine, Maastricht University Medical Center+,
      Maastricht, the Netherlands.
AD  - School for Cardiovascular Diseases (CARIM), Maastricht University Medical
      Center+, Maastricht, the Netherlands.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20181016
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
SB  - IM
MH  - Adult
MH  - Aged
MH  - Atrophy/diagnosis/epidemiology/etiology/pathology
MH  - Brain/diagnostic imaging/*pathology
MH  - Brain Diseases/*diagnosis/epidemiology/etiology/pathology
MH  - Cohort Studies
MH  - Diabetes Mellitus, Type 2/complications/diagnosis/epidemiology/pathology
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Netherlands/epidemiology
MH  - Prediabetic State/*complications/diagnosis/epidemiology/pathology
MH  - Risk Factors
MH  - Stroke/diagnosis/epidemiology/etiology/pathology
EDAT- 2018/10/18 06:00
MHDA- 2019/02/20 06:00
CRDT- 2018/10/18 06:00
PHST- 2018/05/24 00:00 [received]
PHST- 2018/09/15 00:00 [accepted]
PHST- 2018/10/18 06:00 [pubmed]
PHST- 2019/02/20 06:00 [medline]
PHST- 2018/10/18 06:00 [entrez]
AID - dc18-1132 [pii]
AID - 10.2337/dc18-1132 [doi]
PST - ppublish
SO  - Diabetes Care. 2018 Dec;41(12):2535-2543. doi: 10.2337/dc18-1132. Epub 2018 Oct
      16.