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Items: 42


Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health.

Ostrander EA, Wang GD, Larson G, vonHoldt BM, Davis BW, Jagannathan V, Hitte C, Wayne RK, Zhang YP; Dog10K Consortium .

Natl Sci Rev. 2019 Jul;6(4):810-824. doi: 10.1093/nsr/nwz049. Epub 2019 Apr 10.


Dog10K: the International Consortium of Canine Genome Sequencing.

Wang GD, Larson G, Kidd JM, vonHoldt BM, Ostrander EA, Zhang YP.

Natl Sci Rev. 2019 Jul;6(4):611-613. doi: 10.1093/nsr/nwz068. Epub 2019 May 29. No abstract available.


Highly heritable and functionally relevant breed differences in dog behaviour.

MacLean EL, Snyder-Mackler N, vonHoldt BM, Serpell JA.

Proc Biol Sci. 2019 Oct 9;286(1912):20190716. doi: 10.1098/rspb.2019.0716. Epub 2019 Oct 2.


Homozygosity for Mobile Element Insertions Associated with WBSCR17 Could Predict Success in Assistance Dog Training Programs.

Tandon D, Ressler K, Petticord D, Papa A, Jiranek J, Wilkinson R, Kartzinel RY, Ostrander EA, Burney N, Borden C, Udell MAR, VonHoldt BM.

Genes (Basel). 2019 Jun 9;10(6). pii: E439. doi: 10.3390/genes10060439.


Urban colonization through multiple genetic lenses: The city-fox phenomenon revisited.

DeCandia AL, Brzeski KE, Heppenheimer E, Caro CV, Camenisch G, Wandeler P, Driscoll C, vonHoldt BM.

Ecol Evol. 2019 Jan 31;9(4):2046-2060. doi: 10.1002/ece3.4898. eCollection 2019 Feb.


High genomic diversity and candidate genes under selection associated with range expansion in eastern coyote (Canis latrans) populations.

Heppenheimer E, Brzeski KE, Hinton JW, Patterson BR, Rutledge LY, DeCandia AL, Wheeldon T, Fain SR, Hohenlohe PA, Kays R, White BN, Chamberlain MJ, vonHoldt BM.

Ecol Evol. 2018 Dec 4;8(24):12641-12655. doi: 10.1002/ece3.4688. eCollection 2018 Dec.


Rediscovery of Red Wolf Ghost Alleles in a Canid Population Along the American Gulf Coast.

Heppenheimer E, Brzeski KE, Wooten R, Waddell W, Rutledge LY, Chamberlain MJ, Stahler DR, Hinton JW, vonHoldt BM.

Genes (Basel). 2018 Dec 10;9(12). pii: E618. doi: 10.3390/genes9120618.


Growth factor gene IGF1 is associated with bill size in the black-bellied seedcracker Pyrenestes ostrinus.

vonHoldt BM, Kartzinel RY, Huber CD, Le Underwood V, Zhen Y, Ruegg K, Lohmueller KE, Smith TB.

Nat Commun. 2018 Nov 19;9(1):4855. doi: 10.1038/s41467-018-07374-9.


Natural re-colonization and admixture of wolves (Canis lupus) in the US Pacific Northwest: challenges for the protection and management of rare and endangered taxa.

Hendricks SA, Schweizer RM, Harrigan RJ, Pollinger JP, Paquet PC, Darimont CT, Adams JR, Waits LP, vonHoldt BM, Hohenlohe PA, Wayne RK.

Heredity (Edinb). 2019 Feb;122(2):133-149. doi: 10.1038/s41437-018-0094-x. Epub 2018 Jun 7.


Widespread, long-term admixture between grey wolves and domestic dogs across Eurasia and its implications for the conservation status of hybrids.

Pilot M, Greco C, vonHoldt BM, Randi E, Jędrzejewski W, Sidorovich VE, Konopiński MK, Ostrander EA, Wayne RK.

Evol Appl. 2018 Mar 8;11(5):662-680. doi: 10.1111/eva.12595. eCollection 2018 Jun.


Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome.

vonHoldt BM, Ji SS, Aardema ML, Stahler DR, Udell MAR, Sinsheimer JS.

Genome Biol Evol. 2018 Jun 1;10(6):1546-1553. doi: 10.1093/gbe/evy112.


Toward an integrative molecular approach to wildlife disease.

DeCandia AL, Dobson AP, vonHoldt BM.

Conserv Biol. 2018 Aug;32(4):798-807. doi: 10.1111/cobi.13083. Epub 2018 Mar 13.


Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs.

vonHoldt BM, Shuldiner E, Koch IJ, Kartzinel RY, Hogan A, Brubaker L, Wanser S, Stahler D, Wynne CDL, Ostrander EA, Sinsheimer JS, Udell MAR.

Sci Adv. 2017 Jul 19;3(7):e1700398. doi: 10.1126/sciadv.1700398. eCollection 2017 Jul.


Response to Hohenlohe et al.

vonHoldt BM, Cahill JA, Gronau I, Shapiro B, Wall J, Wayne RK.

Sci Adv. 2017 Jun 7;3(6):e1701233. doi: 10.1126/sciadv.1701233. eCollection 2017 Jun.


A Statistical Framework to Identify Deviation from Time Linearity in Epigenetic Aging.

Snir S, vonHoldt BM, Pellegrini M.

PLoS Comput Biol. 2016 Nov 11;12(11):e1005183. doi: 10.1371/journal.pcbi.1005183. eCollection 2016 Nov.


Whole-genome sequence analysis shows that two endemic species of North American wolf are admixtures of the coyote and gray wolf.

vonHoldt BM, Cahill JA, Fan Z, Gronau I, Robinson J, Pollinger JP, Shapiro B, Wall J, Wayne RK.

Sci Adv. 2016 Jul 27;2(7):e1501714. doi: 10.1126/sciadv.1501714. eCollection 2016 Jul.


Pervasive Effects of Aging on Gene Expression in Wild Wolves.

Charruau P, Johnston RA, Stahler DR, Lea A, Snyder-Mackler N, Smith DW, vonHoldt BM, Cole SW, Tung J, Wayne RK.

Mol Biol Evol. 2016 Aug;33(8):1967-78. doi: 10.1093/molbev/msw072. Epub 2016 Apr 15.


The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves.

Janowitz Koch I, Clark MM, Thompson MJ, Deere-Machemer KA, Wang J, Duarte L, Gnanadesikan GE, McCoy EL, Rubbi L, Stahler DR, Pellegrini M, Ostrander EA, Wayne RK, Sinsheimer JS, vonHoldt BM.

Mol Ecol. 2016 Apr;25(8):1838-55. doi: 10.1111/mec.13480. Epub 2016 Jan 18.


Genomic Flatlining in the Endangered Island Fox.

Robinson JA, Ortega-Del Vecchyo D, Fan Z, Kim BY, vonHoldt BM, Marsden CD, Lohmueller KE, Wayne RK.

Curr Biol. 2016 May 9;26(9):1183-9. doi: 10.1016/j.cub.2016.02.062. Epub 2016 Apr 21.


Admixture mapping identifies introgressed genomic regions in North American canids.

vonHoldt BM, Kays R, Pollinger JP, Wayne RK.

Mol Ecol. 2016 Jun;25(11):2443-53. doi: 10.1111/mec.13667. Epub 2016 May 12.


Epigenetics in ecology and evolution: what we know and what we need to know.

Verhoeven KJ, vonHoldt BM, Sork VL.

Mol Ecol. 2016 Apr;25(8):1631-8. doi: 10.1111/mec.13617. No abstract available.


Genetic subdivision and candidate genes under selection in North American grey wolves.

Schweizer RM, vonHoldt BM, Harrigan R, Knowles JC, Musiani M, Coltman D, Novembre J, Wayne RK.

Mol Ecol. 2016 Jan;25(1):380-402. doi: 10.1111/mec.13364. Epub 2015 Nov 5.


Mexican Wolves Are a Valid Subspecies and an Appropriate Conservation Target.

Fredrickson RJ, Hedrick PW, Wayne RK, vonHoldt BM, Phillips MK.

J Hered. 2015 Jul-Aug;106(4):415-6. doi: 10.1093/jhered/esv028. Epub 2015 May 11. No abstract available.


Galaxy tools to study genome diversity.

Bedoya-Reina OC, Ratan A, Burhans R, Kim HL, Giardine B, Riemer C, Li Q, Olson TL, Loughran TP Jr, Vonholdt BM, Perry GH, Schuster SC, Miller W.

Gigascience. 2013 Dec 30;2(1):17. doi: 10.1186/2047-217X-2-17.


Genome-wide signatures of population bottlenecks and diversifying selection in European wolves.

Pilot M, Greco C, vonHoldt BM, Jędrzejewska B, Randi E, Jędrzejewski W, Sidorovich VE, Ostrander EA, Wayne RK.

Heredity (Edinb). 2014 Apr;112(4):428-42. doi: 10.1038/hdy.2013.122. Epub 2013 Dec 18.


Artificial selection on brain-expressed genes during the domestication of dog.

Li Y, Vonholdt BM, Reynolds A, Boyko AR, Wayne RK, Wu DD, Zhang YP.

Mol Biol Evol. 2013 Aug;30(8):1867-76. doi: 10.1093/molbev/mst088. Epub 2013 May 8.


A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.

Karyadi DM, Karlins E, Decker B, vonHoldt BM, Carpintero-Ramirez G, Parker HG, Wayne RK, Ostrander EA.

PLoS Genet. 2013 Mar;9(3):e1003409. doi: 10.1371/journal.pgen.1003409. Epub 2013 Mar 28.


Identification of recent hybridization between gray wolves and domesticated dogs by SNP genotyping.

vonHoldt BM, Pollinger JP, Earl DA, Parker HG, Ostrander EA, Wayne RK.

Mamm Genome. 2013 Feb;24(1-2):80-8. doi: 10.1007/s00335-012-9432-0. Epub 2012 Oct 12.


Recent retrotransposon insertions are methylated and phylogenetically clustered in japonica rice (Oryza sativa spp. japonica).

Vonholdt BM, Takuno S, Gaut BS.

Mol Biol Evol. 2012 Oct;29(10):3193-203. Epub 2012 May 15.


Evolutionary genomics of dog domestication.

Wayne RK, vonHoldt BM.

Mamm Genome. 2012 Feb;23(1-2):3-18. doi: 10.1007/s00335-011-9386-7. Epub 2012 Jan 22. Review.


Breed-specific ancestry studies and genome-wide association analysis highlight an association between the MYH9 gene and heat tolerance in Alaskan sprint racing sled dogs.

Huson HJ, vonHoldt BM, Rimbault M, Byers AM, Runstadler JA, Parker HG, Ostrander EA.

Mamm Genome. 2012 Feb;23(1-2):178-94. doi: 10.1007/s00335-011-9374-y. Epub 2011 Nov 22.


Kin encounter rate and inbreeding avoidance in canids.

Geffen E, Kam M, Hefner R, Hersteinsson P, Angerbjörn A, Dalèn L, Fuglei E, Norèn K, Adams JR, Vucetich J, Meier TJ, Mech LD, Vonholdt BM, Stahler DR, Wayne RK.

Mol Ecol. 2011 Dec;20(24):5348-58. doi: 10.1111/j.1365-294X.2011.05358.x. Epub 2011 Nov 11.


A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids.

vonHoldt BM, Pollinger JP, Earl DA, Knowles JC, Boyko AR, Parker H, Geffen E, Pilot M, Jedrzejewski W, Jedrzejewska B, Sidorovich V, Greco C, Randi E, Musiani M, Kays R, Bustamante CD, Ostrander EA, Novembre J, Wayne RK.

Genome Res. 2011 Aug;21(8):1294-305. doi: 10.1101/gr.116301.110. Epub 2011 May 12.


A novel assessment of population structure and gene flow in grey wolf populations of the Northern Rocky Mountains of the United States.

vonHoldt BM, Stahler DR, Bangs EE, Smith DW, Jimenez MD, Mack CM, Niemeyer CC, Pollinger JP, Wayne RK.

Mol Ecol. 2010 Oct;19(20):4412-27. doi: 10.1111/j.1365-294X.2010.04769.x. Epub 2010 Aug 16.


A simple genetic architecture underlies morphological variation in dogs.

Boyko AR, Quignon P, Li L, Schoenebeck JJ, Degenhardt JD, Lohmueller KE, Zhao K, Brisbin A, Parker HG, vonHoldt BM, Cargill M, Auton A, Reynolds A, Elkahloun AG, Castelhano M, Mosher DS, Sutter NB, Johnson GS, Novembre J, Hubisz MJ, Siepel A, Wayne RK, Bustamante CD, Ostrander EA.

PLoS Biol. 2010 Aug 10;8(8):e1000451. doi: 10.1371/journal.pbio.1000451.


Heterozygosity of the Yellowstone wolves.

Jankovic I, vonHoldt BM, Rosenberg NA.

Mol Ecol. 2010 Aug;19(16):3246-9. doi: 10.1111/j.1365-294X.2010.04746.x. Epub 2010 Jul 28. No abstract available.


Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication.

Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, Degenhardt JD, Boyko AR, Earl DA, Auton A, Reynolds A, Bryc K, Brisbin A, Knowles JC, Mosher DS, Spady TC, Elkahloun A, Geffen E, Pilot M, Jedrzejewski W, Greco C, Randi E, Bannasch D, Wilton A, Shearman J, Musiani M, Cargill M, Jones PG, Qian Z, Huang W, Ding ZL, Zhang YP, Bustamante CD, Ostrander EA, Novembre J, Wayne RK.

Nature. 2010 Apr 8;464(7290):898-902. doi: 10.1038/nature08837. Epub 2010 Mar 17.


Coat variation in the domestic dog is governed by variants in three genes.

Cadieu E, Neff MW, Quignon P, Walsh K, Chase K, Parker HG, Vonholdt BM, Rhue A, Boyko A, Byers A, Wong A, Mosher DS, Elkahloun AG, Spady TC, André C, Lark KG, Cargill M, Bustamante CD, Wayne RK, Ostrander EA.

Science. 2009 Oct 2;326(5949):150-3. doi: 10.1126/science.1177808. Epub 2009 Aug 27.


An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs.

Parker HG, VonHoldt BM, Quignon P, Margulies EH, Shao S, Mosher DS, Spady TC, Elkahloun A, Cargill M, Jones PG, Maslen CL, Acland GM, Sutter NB, Kuroki K, Bustamante CD, Wayne RK, Ostrander EA.

Science. 2009 Aug 21;325(5943):995-8. doi: 10.1126/science.1173275. Epub 2009 Jul 16.


Molecular and evolutionary history of melanism in North American gray wolves.

Anderson TM, vonHoldt BM, Candille SI, Musiani M, Greco C, Stahler DR, Smith DW, Padhukasahasram B, Randi E, Leonard JA, Bustamante CD, Ostrander EA, Tang H, Wayne RK, Barsh GS.

Science. 2009 Mar 6;323(5919):1339-43. doi: 10.1126/science.1165448. Epub 2009 Feb 5.


The genealogy and genetic viability of reintroduced Yellowstone grey wolves.

Vonholdt BM, Stahler DR, Smith DW, Earl DA, Pollinger JP, Wayne RK.

Mol Ecol. 2008 Jan;17(1):252-74. Epub 2007 Sep 18.


The singular history of a canine transmissible tumor.

VonHoldt BM, Ostrander EA.

Cell. 2006 Aug 11;126(3):445-7. Review.

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