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Items: 28


Microproteomics and Immunohistochemistry Reveal Differences in Aldo-Keto Reductase Family 1 Member C3 in Tissue Specimens of Ulcerative Colitis and Crohn's Disease.

Arafah K, Kriegsmann M, Renner M, Lasitschka F, Fresnais M, Kriegsmann K, von Winterfeld M, Goeppert B, Kriegsmann J, Casadonte R, Kazdal D, Bulet P, Longuespée R.

Proteomics Clin Appl. 2020 Jan 31:e1900110. doi: 10.1002/prca.201900110. [Epub ahead of print]


Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.

Arnold A, Daum S, von Winterfeld M, Berg E, Hummel M, Horst D, Rau B, Stein U, Treese C.

Pathol Res Pract. 2019 Nov;215(11):152662. doi: 10.1016/j.prp.2019.152662. Epub 2019 Sep 19.


RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples.

Kirchner M, Neumann O, Volckmar AL, Stögbauer F, Allgäuer M, Kazdal D, Budczies J, Rempel E, Brandt R, Talla SB, von Winterfeld M, Leichsenring J, Bochtler T, Krämer A, Springfeld C, Schirmacher P, Penzel R, Endris V, Stenzinger A.

Cancers (Basel). 2019 Sep 5;11(9). pii: E1309. doi: 10.3390/cancers11091309.


Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts.

Kazdal D, Endris V, Allgäuer M, Kriegsmann M, Leichsenring J, Volckmar AL, Harms A, Kirchner M, Kriegsmann K, Neumann O, Brandt R, Talla SB, Rempel E, Ploeger C, von Winterfeld M, Christopoulos P, Merino DM, Stewart M, Allen J, Bischoff H, Meister M, Muley T, Herth F, Penzel R, Warth A, Winter H, Fröhling S, Peters S, Swanton C, Thomas M, Schirmacher P, Budczies J, Stenzinger A.

J Thorac Oncol. 2019 Nov;14(11):1935-1947. doi: 10.1016/j.jtho.2019.07.006. Epub 2019 Jul 23.


Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases.

Volckmar AL, Leichsenring J, Kirchner M, Christopoulos P, Neumann O, Budczies J, Morais de Oliveira CM, Rempel E, Buchhalter I, Brandt R, Allgäuer M, Talla SB, von Winterfeld M, Herpel E, Goeppert B, Lier A, Winter H, Brummer T, Fröhling S, Faehling M, Fischer JR, Heußel CP, Herth F, Lasitschka F, Schirmacher P, Thomas M, Endris V, Penzel R, Stenzinger A.

Int J Cancer. 2019 Aug 1;145(3):649-661. doi: 10.1002/ijc.32133. Epub 2019 Feb 19.


Implementing tumor mutational burden (TMB) analysis in routine diagnostics-a primer for molecular pathologists and clinicians.

Allgäuer M, Budczies J, Christopoulos P, Endris V, Lier A, Rempel E, Volckmar AL, Kirchner M, von Winterfeld M, Leichsenring J, Neumann O, Fröhling S, Penzel R, Thomas M, Schirmacher P, Stenzinger A.

Transl Lung Cancer Res. 2018 Dec;7(6):703-715. doi: 10.21037/tlcr.2018.08.14. Review.


Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real-life analysis of three larger gene panels.

Endris V, Buchhalter I, Allgäuer M, Rempel E, Lier A, Volckmar AL, Kirchner M, von Winterfeld M, Leichsenring J, Neumann O, Penzel R, Weichert W, Glimm H, Fröhling S, Winter H, Herth F, Thomas M, Schirmacher P, Budczies J, Stenzinger A.

Int J Cancer. 2019 May 1;144(9):2303-2312. doi: 10.1002/ijc.32002. Epub 2019 Feb 4.


Size matters: Dissecting key parameters for panel-based tumor mutational burden analysis.

Buchhalter I, Rempel E, Endris V, Allgäuer M, Neumann O, Volckmar AL, Kirchner M, Leichsenring J, Lier A, von Winterfeld M, Penzel R, Christopoulos P, Thomas M, Fröhling S, Schirmacher P, Budczies J, Stenzinger A.

Int J Cancer. 2019 Feb 15;144(4):848-858. doi: 10.1002/ijc.31878. Epub 2018 Dec 4.


Next generation sequencing of the cellular and liquid fraction of pancreatic cyst fluid supports discrimination of IPMN from pseudocysts and reveals cases with multiple mutated driver clones: First findings from the prospective ZYSTEUS biomarker study.

Volckmar AL, Endris V, Gaida MM, Leichsenring J, Stögbauer F, Allgäuer M, von Winterfeld M, Penzel R, Kirchner M, Brandt R, Neumann O, Sültmann H, Schirmacher P, Rudi J, Schmitz D, Stenzinger A.

Genes Chromosomes Cancer. 2019 Jan;58(1):3-11. doi: 10.1002/gcc.22682. Epub 2018 Oct 17.


High protein and mRNA expression levels of TUBB3 (class III ß-tubulin) are associated with aggressive tumor features in esophageal adenocarcinomas.

Loeser H, Schallenberg S, von Winterfeld M, Tharun L, Alakus H, Hölscher A, Bollschweiler E, Buettner R, Zander T, Quaas A.

Oncotarget. 2017 Dec 11;8(70):115179-115189. doi: 10.18632/oncotarget.23112. eCollection 2017 Dec 29.


Predictive value of peritoneal cancer index for survival in patients with mucinous peritoneal malignancies treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a single centre experience.

Brandl A, Weiss S, von Winterfeld M, Krannich A, Feist M, Pratschke J, Raue W, Rau B.

Int J Hyperthermia. 2018 Aug;34(5):512-517. doi: 10.1080/02656736.2017.1351627. Epub 2017 Jul 26.


The association between microsatellite instability and lymph node count in colorectal cancer.

Arnold A, Kloor M, Jansen L, Chang-Claude J, Brenner H, von Winterfeld M, Hoffmeister M, Bläker H.

Virchows Arch. 2017 Jul;471(1):57-64. doi: 10.1007/s00428-017-2150-y. Epub 2017 May 23.


DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.

Mamlouk S, Childs LH, Aust D, Heim D, Melching F, Oliveira C, Wolf T, Durek P, Schumacher D, Bläker H, von Winterfeld M, Gastl B, Möhr K, Menne A, Zeugner S, Redmer T, Lenze D, Tierling S, Möbs M, Weichert W, Folprecht G, Blanc E, Beule D, Schäfer R, Morkel M, Klauschen F, Leser U, Sers C.

Nat Commun. 2017 Jan 25;8:14093. doi: 10.1038/ncomms14093.


Mutations in genes encoding PI3K-AKT and MAPK signaling define anogenital papillary hidradenoma.

Pfarr N, Sinn HP, Klauschen F, Flechtenmacher C, Bockmayr M, Ridinger K, von Winterfeld M, Warth A, Lorenz K, Budczies J, Penzel R, Lennerz JK, Endris V, Weichert W, Stenzinger A.

Genes Chromosomes Cancer. 2016 Feb;55(2):113-9. doi: 10.1002/gcc.22315. Epub 2015 Oct 23.


Personalized Therapy for Generalized Lymphatic Anomaly/Gorham-Stout Disease With a Combination of Sunitinib and Taxol.

Rössler J, Saueressig U, Kayser G, von Winterfeld M, Klement GL.

J Pediatr Hematol Oncol. 2015 Nov;37(8):e481-5. doi: 10.1097/MPH.0000000000000436. Review.


Inflammatory bowel disease (IBD)-like disease in a case of a 33-year old man with glycogenosis 1b.

Volz MS, Nassir M, Treese C, von Winterfeld M, Plöckinger U, Epple HJ, Siegmund B.

BMC Gastroenterol. 2015 Apr 8;15:45. doi: 10.1186/s12876-015-0271-9.


High Impact of Histopathological Remission for Prognosis after Perioperative Chemotherapy with ECF and ECF-Like Regimens for Gastric and Gastroesophageal Adenocarcinoma.

Bichev D, Treese C, von Winterfeld M, Breithaupt K, Dogan Y, Schmidt SC, Daum S, Thuss-Patience PC.

Oncology. 2015;89(2):95-102. doi: 10.1159/000376550. Epub 2015 Mar 21.


The landscape of metastatic progression patterns across major human cancers.

Budczies J, von Winterfeld M, Klauschen F, Bockmayr M, Lennerz JK, Denkert C, Wolf T, Warth A, Dietel M, Anagnostopoulos I, Weichert W, Wittschieber D, Stenzinger A.

Oncotarget. 2015 Jan 1;6(1):570-83.


Frequency of therapy-relevant staging shifts in colorectal cancer through the introduction of pN1c in the 7th TNM edition.

von Winterfeld M, Hoffmeister M, Ingold-Heppner B, Jansen L, Tao S, Herpel E, Schirmacher P, Dietel M, Chang-Claude J, Autschbach F, Brenner H, Bläker H.

Eur J Cancer. 2014 Nov;50(17):2958-65. doi: 10.1016/j.ejca.2014.09.002. Epub 2014 Sep 30.


Lymph node count and prognosis in colorectal cancer: the influence of examination quality.

Bläker H, Hildebrandt B, Riess H, von Winterfeld M, Ingold-Heppner B, Roth W, Kloor M, Schirmacher P, Dietel M, Tao S, Jansen L, Chang-Claude J, Ulrich A, Brenner H, Hoffmeister M.

Int J Cancer. 2015 Apr 15;136(8):1957-66. doi: 10.1002/ijc.29221. Epub 2014 Sep 24.


Comprehensive analysis of clinico-pathological data reveals heterogeneous relations between atherosclerosis and cancer.

Budczies J, von Winterfeld M, Klauschen F, Kimmritz AC, Daniel JM, Warth A, Endris V, Denkert C, Pfeiffer H, Weichert W, Dietel M, Wittschieber D, Stenzinger A.

J Clin Pathol. 2014 Jun;67(6):482-90. doi: 10.1136/jclinpath-2013-202148. Epub 2014 Feb 11.


Who is at risk for diagnostic discrepancies? Comparison of pre- and postmortal diagnoses in 1800 patients of 3 medical decades in East and West Berlin.

Wittschieber D, Klauschen F, Kimmritz AC, von Winterfeld M, Kamphues C, Scholman HJ, Erbersdobler A, Pfeiffer H, Denkert C, Dietel M, Weichert W, Budczies J, Stenzinger A.

PLoS One. 2012;7(5):e37460. doi: 10.1371/journal.pone.0037460. Epub 2012 May 22.


Quantitative analysis of diagnostic guidelines for HER2-status assessment.

Stenzinger A, von Winterfeld M, Aulmann S, Warth A, Weichert W, Denkert C, Rüschoff J, Dietel M, Klauschen F.

J Mol Diagn. 2012 May-Jun;14(3):199-205. doi: 10.1016/j.jmoldx.2012.01.012.


High extracellular matrix metalloproteinase inducer/CD147 expression is strongly and independently associated with poor prognosis in colorectal cancer.

Stenzinger A, Wittschieber D, von Winterfeld M, Goeppert B, Kamphues C, Weichert W, Dietel M, Rabien A, Klauschen F.

Hum Pathol. 2012 Sep;43(9):1471-81. doi: 10.1016/j.humpath.2011.10.023. Epub 2012 Mar 12.


Reversion-inducing cysteine-rich protein with Kazal motif (RECK) expression: an independent prognostic marker of survival in colorectal cancer.

Stenzinger A, von Winterfeld M, Rabien A, Warth A, Kamphues C, Dietel M, Weichert W, Klauschen F, Wittschieber D.

Hum Pathol. 2012 Aug;43(8):1314-21. doi: 10.1016/j.humpath.2011.10.012. Epub 2012 Mar 6.


High nuclear poly-(ADP-ribose)-polymerase expression is prognostic of improved survival in pancreatic cancer.

Klauschen F, von Winterfeld M, Stenzinger A, Sinn BV, Budczies J, Kamphues C, Bahra M, Wittschieber D, Weichert W, Striefler J, Riess H, Dietel M, Denkert C.

Histopathology. 2012 Sep;61(3):409-16. doi: 10.1111/j.1365-2559.2012.04225.x. Epub 2012 Mar 2.


Hemodynamic support by left ventricular assist devices reduces cardiomyocyte DNA content in the failing human heart.

Wohlschlaeger J, Levkau B, Brockhoff G, Schmitz KJ, von Winterfeld M, Takeda A, Takeda N, Stypmann J, Vahlhaus C, Schmid C, Pomjanski N, Böcking A, Baba HA.

Circulation. 2010 Mar 2;121(8):989-96. doi: 10.1161/CIRCULATIONAHA.108.808071. Epub 2010 Feb 16.


Decreased myocardial chromogranin a expression and colocalization with brain natriuretic peptide during reverse cardiac remodeling after ventricular unloading.

Wohlschlaeger J, von Winterfeld M, Milting H, El Banayosy A, Schmitz KJ, Takeda A, Takeda N, Azhari P, Schmid C, August C, Schmid KW, Baba HA.

J Heart Lung Transplant. 2008 Apr;27(4):442-9. doi: 10.1016/j.healun.2008.01.017.


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