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Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method.

Zhao W, Michalik D, Ferguson S, Hofstetter W, Lemaître J, von Rechenberg B, Bowen P.

Nat Commun. 2019 May 2;10(1):2062. doi: 10.1038/s41467-019-09673-1.


Proof of concept: hip joint damage occurs at the zone of femoroacetabular impingement (FAI) in an experimental FAI sheep model.

Zurmühle CA, Schmaranzer F, Nuss K, Wolfer N, Ryan MK, Zheng G, von Rechenberg B, Tannast M.

Osteoarthritis Cartilage. 2019 Jul;27(7):1075-1083. doi: 10.1016/j.joca.2019.04.001. Epub 2019 Apr 13.


Do dGEMRIC and T2 Imaging Correlate With Histologic Cartilage Degeneration in an Experimental Ovine FAI Model?

Schmaranzer F, Arendt L, Liechti EF, Nuss K, von Rechenberg B, Kircher PR, Tannast M.

Clin Orthop Relat Res. 2019 May;477(5):990-1003. doi: 10.1097/CORR.0000000000000593.


Comparison of hock- and footpad-injection as a prostate adenocarcinoma model in rats.

Richter H, Karol A, Nuss K, Lenisa A, Bruellmann E, Maudens SS, Hoffmann H, von Rechenberg B, Kircher PR.

BMC Vet Res. 2018 Nov 6;14(1):327. doi: 10.1186/s12917-018-1659-x.


Inhibition of calpain delays early muscle atrophy after rotator cuff tendon release in sheep.

Ruoss S, Kindt P, Oberholzer L, Rohner M, Jungck L, Abdel-Aziz S, Fitze D, Rosskopf AB, Klein K, von Rechenberg B, Gerber C, Wieser K, Flück M.

Physiol Rep. 2018 Nov;6(21):e13833. doi: 10.14814/phy2.13833.


Neurectomy preserves fast fibers when combined with tenotomy of infraspinatus muscle via upregulation of myogenesis.

Flück M, Valdivieso P, Ruoss S, von Rechenberg B, Benn MC, Meyer DC, Wieser K, Gerber C.

Muscle Nerve. 2019 Jan;59(1):100-107. doi: 10.1002/mus.26316. Epub 2018 Dec 4.


Vascular supply of the femoral head in sheep-Implications for the ovine femoroacetabular impingement model.

Tannast M, Wolfer N, Ryan MK, Nuss KM, von Rechenberg B, Steppacher SD.

J Orthop Res. 2018 Sep;36(9):2340-2348. doi: 10.1002/jor.23897. Epub 2018 Apr 24.


Recovery of low volumes of wear debris from rat stifle joint tissues using a novel particle isolation method.

Patel J, Lal S, Nuss K, Wilshaw SP, von Rechenberg B, Hall RM, Tipper JL.

Acta Biomater. 2018 Apr 15;71:339-350. doi: 10.1016/j.actbio.2018.02.030. Epub 2018 Mar 2.


Femoral osteochondroplasty can be performed effectively without the risk of avascular necrosis or femoral neck fractures in an experimental ovine FAI model.

Schmaranzer F, Arendt L, Lerch TD, Steppacher SD, Nuss K, Wolfer N, Dawson HE, von Rechenberg B, Kircher PR, Tannast M.

Osteoarthritis Cartilage. 2018 Jan;26(1):128-137. doi: 10.1016/j.joca.2017.10.009. Epub 2017 Oct 20.


Local effect of zoledronic acid on new bone formation in posterolateral spinal fusion with demineralized bone matrix in a murine model.

Zwolak P, Farei-Campagna J, Jentzsch T, von Rechenberg B, Werner CM.

Arch Orthop Trauma Surg. 2018 Jan;138(1):13-18. doi: 10.1007/s00402-017-2818-4. Epub 2017 Oct 10.


Costamere protein expression and tissue composition of rotator cuff muscle after tendon release in sheep.

Ruoss S, Möhl CB, Benn MC, von Rechenberg B, Wieser K, Meyer DC, Gerber C, Flück M.

J Orthop Res. 2018 Jan;36(1):272-281. doi: 10.1002/jor.23624. Epub 2017 Aug 23.


Evaluation of the Modern Luque Trolley Construct for the Treatment of Early-onset Scoliosis Using a Gliding Implant in an Immature Animal Model.

Ouellet JA, Ferland CE, Klein K, Racloz G, Klein K, Richter H, Steffen T, von Rechenberg B.

Clin Spine Surg. 2017 May;30(4):E460-E465. doi: 10.1097/BSD.0000000000000260.


Muscle Degeneration Associated With Rotator Cuff Tendon Release and/or Denervation in Sheep.

Gerber C, Meyer DC, Flück M, Valdivieso P, von Rechenberg B, Benn MC, Wieser K.

Am J Sports Med. 2017 Mar;45(3):651-658. doi: 10.1177/0363546516677254. Epub 2016 Dec 13.


Neer Award 2016: reduced muscle degeneration and decreased fatty infiltration after rotator cuff tear in a poly(ADP-ribose) polymerase 1 (PARP-1) knock-out mouse model.

Kuenzler MB, Nuss K, Karol A, Schär MO, Hottiger M, Raniga S, Kenkel D, von Rechenberg B, Zumstein MA.

J Shoulder Elbow Surg. 2017 May;26(5):733-744. doi: 10.1016/j.jse.2016.11.009. Epub 2017 Jan 25.


Ethical use of animal models in musculoskeletal research.

Allen MJ, Hankenson KD, Goodrich L, Boivin GP, von Rechenberg B.

J Orthop Res. 2017 Apr;35(4):740-751. doi: 10.1002/jor.23485. Epub 2017 Jan 17.


Dynamic Stabilization of Simple Fractures With Active Plates Delivers Stronger Healing Than Conventional Compression Plating.

Bottlang M, Tsai S, Bliven EK, von Rechenberg B, Kindt P, Augat P, Henschel J, Fitzpatrick DC, Madey SM.

J Orthop Trauma. 2017 Feb;31(2):71-77. doi: 10.1097/BOT.0000000000000732.


Regenerative Potential of Tissue-Engineered Nasal Chondrocytes in Goat Articular Cartilage Defects.

Mumme M, Steinitz A, Nuss KM, Klein K, Feliciano S, Kronen P, Jakob M, von Rechenberg B, Martin I, Barbero A, Pelttari K.

Tissue Eng Part A. 2016 Nov;22(21-22):1286-1295. Epub 2016 Oct 11.


Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep.

Flück M, Ruoss S, Möhl CB, Valdivieso P, Benn MC, von Rechenberg B, Laczko E, Hu J, Wieser K, Meyer DC, Gerber C.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):382-395. doi: 10.1016/j.jsbmb.2016.08.005. Epub 2016 Aug 12.


Measuring Rabbit (Oryctolagus cuniculus) Tooth Growth and Eruption by Fluorescence Markers and Bur Marks.

Wyss F, Müller J, Clauss M, Kircher P, Geyer H, von Rechenberg B, Hatt JM.

J Vet Dent. 2016 Mar;33(1):39-46.


Dynamic Stabilization with Active Locking Plates Delivers Faster, Stronger, and More Symmetric Fracture-Healing.

Bottlang M, Tsai S, Bliven EK, von Rechenberg B, Klein K, Augat P, Henschel J, Fitzpatrick DC, Madey SM.

J Bone Joint Surg Am. 2016 Mar 16;98(6):466-74. doi: 10.2106/JBJS.O.00705.


Anabolic Steroids Reduce Muscle Degeneration Associated With Rotator Cuff Tendon Release in Sheep.

Gerber C, Meyer DC, Flück M, Benn MC, von Rechenberg B, Wieser K.

Am J Sports Med. 2015 Oct;43(10):2393-400. doi: 10.1177/0363546515596411. Epub 2015 Aug 24.


Titanium and hydroxyapatite coating of polyetheretherketone and carbon fiber-reinforced polyetheretherketone: A pilot study in sheep.

Stübinger S, Drechsler A, Bürki A, Klein K, Kronen P, von Rechenberg B.

J Biomed Mater Res B Appl Biomater. 2016 Aug;104(6):1182-91. doi: 10.1002/jbm.b.33471. Epub 2015 Jun 11.


In vitro investigations of a novel wound dressing concept based on biodegradable polyurethane.

Rottmar M, Richter M, Mäder X, Grieder K, Nuss K, Karol A, von Rechenberg B, Zimmermann E, Buser S, Dobmann A, Blume J, Bruinink A.

Sci Technol Adv Mater. 2015 May 20;16(3):034606. eCollection 2015 Jun.


Dynamization at the near cortex in locking plate osteosynthesis by means of dynamic locking screws: an experimental study of transverse tibial osteotomies in sheep.

Richter H, Plecko M, Andermatt D, Frigg R, Kronen PW, Klein K, Nuss K, Ferguson SJ, Stöckle U, von Rechenberg B.

J Bone Joint Surg Am. 2015 Feb 4;97(3):208-15. doi: 10.2106/JBJS.M.00529.


Osseointegration of titanium implants functionalised with phosphoserine-tethered poly(epsilon-lysine) dendrons: a comparative study with traditional surface treatments in sheep.

Stübinger S, Nuss K, Bürki A, Mosch I, le Sidler M, Meikle ST, von Rechenberg B, Santin M.

J Mater Sci Mater Med. 2015 Feb;26(2):87. doi: 10.1007/s10856-015-5433-3. Epub 2015 Feb 3.


Preliminary study on carprofen concentration measurements after transcutaneous treatment with Vetdrop® in a microfracture joint defect model in sheep.

Sidler M, Fouché N, Meth I, von Hahn F, von Rechenberg B, Kronen PW.

BMC Vet Res. 2014 Dec 9;10:268. doi: 10.1186/s12917-014-0268-6.


Effect of grain size and microporosity on the in vivo behaviour of β-tricalcium phosphate scaffolds.

Lapczyna H, Galea L, Wüst S, Bohner M, Jerban S, Sweedy A, Doebelin N, van Garderen N, Hofmann S, Baroud G, Müller R, von Rechenberg B.

Eur Cell Mater. 2014 Oct 23;28:299-319.


A novel multi-phosphonate surface treatment of titanium dental implants: a study in sheep.

von Salis-Soglio M, Stübinger S, Sidler M, Klein K, Ferguson SJ, Kämpf K, Zlinszky K, Buchini S, Curno R, Péchy P, Aronsson BO, von Rechenberg B.

J Funct Biomater. 2014 Sep 11;5(3):135-57. doi: 10.3390/jfb5030135.


Biochemical MRI predicts hip osteoarthritis in an experimental ovine femoroacetabular impingement model.

Siebenrock KA, Kienle KP, Steppacher SD, Tannast M, Mamisch TC, von Rechenberg B.

Clin Orthop Relat Res. 2015 Apr;473(4):1318-24. doi: 10.1007/s11999-014-3849-6.


Adult human neural crest-derived cells for articular cartilage repair.

Pelttari K, Pippenger B, Mumme M, Feliciano S, Scotti C, Mainil-Varlet P, Procino A, von Rechenberg B, Schwamborn T, Jakob M, Cillo C, Barbero A, Martin I.

Sci Transl Med. 2014 Aug 27;6(251):251ra119. doi: 10.1126/scitranslmed.3009688.


Evaluation of local cancellous bone amelioration by poly-L-DL-lactide copolymers to improve primary stability of dental implants: a biomechanical study in sheep.

Stübinger S, Waser J, Hefti T, Drechsler A, Sidler M, Klein K, von Rechenberg B, Schlottig F.

Clin Oral Implants Res. 2015 May;26(5):572-80. doi: 10.1111/clr.12445. Epub 2014 Jul 2.


Comparison of two dental implant surface modifications on implants with same macrodesign: an experimental study in the pelvic sheep model.

Ernst S, Stübinger S, Schüpbach P, Sidler M, Klein K, Ferguson SJ, von Rechenberg B.

Clin Oral Implants Res. 2015 Aug;26(8):898-908. doi: 10.1111/clr.12411. Epub 2014 May 21.


Therapeutic potential of adipose-derived stromal cells in age-related osteoporosis.

Mirsaidi A, Genelin K, Vetsch JR, Stanger S, Theiss F, Lindtner RA, von Rechenberg B, Blauth M, Müller R, Kuhn GA, Hofmann Boss S, Ebner HL, Richards PJ.

Biomaterials. 2014 Aug;35(26):7326-35. doi: 10.1016/j.biomaterials.2014.05.016. Epub 2014 Jun 2.


Tendon response to pharmaco-mechanical stimulation of the chronically retracted rotator cuff in sheep.

Wieser K, Farshad M, Meyer DC, Conze P, von Rechenberg B, Gerber C.

Knee Surg Sports Traumatol Arthrosc. 2015 Feb;23(2):577-84. doi: 10.1007/s00167-014-3037-y. Epub 2014 May 4.


[Osteoconductive behaviour of beta-tricalcium phosphate ceramics in osteoporotic, metaphyseal bone defects of the distal radius].

Hainich J, von Rechenberg B, Jakubietz RG, Jakubietz MG, Giovanoli P, Grünert JG.

Handchir Mikrochir Plast Chir. 2014 Feb;46(1):12-7. doi: 10.1055/s-0034-1366999. Epub 2014 Feb 26. German.


Histological remodelling of demineralised bone matrix allograft in posterolateral fusion of the spine--an ex vivo study.

Bouaicha S, von Rechenberg B, Osterhoff G, Wanner GA, Simmen HP, Werner CM.

BMC Surg. 2013 Dec 13;13:58. doi: 10.1186/1471-2482-13-58.


Osteoanabolic effect of alendronate and zoledronate on bone marrow stromal cells (BMSCs) isolated from aged female osteoporotic patients and its implications for their mode of action in the treatment of age-related bone loss.

Lindtner RA, Tiaden AN, Genelin K, Ebner HL, Manzl C, Klawitter M, Sitte I, von Rechenberg B, Blauth M, Richards PJ.

Osteoporos Int. 2014 Mar;25(3):1151-61. doi: 10.1007/s00198-013-2494-3. Epub 2013 Aug 22.


Remodeling of tissue-engineered bone structures in vivo.

Hofmann S, Hilbe M, Fajardo RJ, Hagenmüller H, Nuss K, Arras M, Müller R, von Rechenberg B, Kaplan DL, Merkle HP, Meinel L.

Eur J Pharm Biopharm. 2013 Sep;85(1):119-29. doi: 10.1016/j.ejpb.2013.02.011.


Biocompatibility and osteoconduction of macroporous silk fibroin implants in cortical defects in sheep.

Uebersax L, Apfel T, Nuss KM, Vogt R, Kim HY, Meinel L, Kaplan DL, Auer JA, Merkle HP, von Rechenberg B.

Eur J Pharm Biopharm. 2013 Sep;85(1):107-18. doi: 10.1016/j.ejpb.2013.05.008.


Impact of IGF-I release kinetics on bone healing: a preliminary study in sheep.

Luginbuehl V, Zoidis E, Meinel L, von Rechenberg B, Gander B, Merkle HP.

Eur J Pharm Biopharm. 2013 Sep;85(1):99-106. doi: 10.1016/j.ejpb.2013.03.004.


A new-generation, low-permeability flow diverting device for treatment of saccular aneurysms.

Mallik AS, Nuss K, Kronen PW, Klein K, Karol A, von Rechenberg B, Rüfenacht DA, Wanke I, Kulcsár Z.

Eur Radiol. 2014 Jan;24(1):12-8. doi: 10.1007/s00330-013-2970-3. Epub 2013 Jul 24.


Bone augmentation for cancellous bone- development of a new animal model.

Klein K, Zamparo E, Kronen PW, Kämpf K, Makara M, Steffen T, von Rechenberg B.

BMC Musculoskelet Disord. 2013 Jul 2;14:200. doi: 10.1186/1471-2474-14-200.


Evaluation of four biodegradable, injectable bone cements in an experimental drill hole model in sheep.

von Rechenberg B, Génot OR, Nuss K, Galuppo L, Fulmer M, Jacobson E, Kronen P, Zlinszky K, Auer JA.

Eur J Pharm Biopharm. 2013 Sep;85(1):130-8. doi: 10.1016/j.ejpb.2013.04.013. Epub 2013 May 13.


Histological and biomechanical analysis of porous additive manufactured implants made by direct metal laser sintering: a pilot study in sheep.

Stübinger S, Mosch I, Robotti P, Sidler M, Klein K, Ferguson SJ, von Rechenberg B.

J Biomed Mater Res B Appl Biomater. 2013 Oct;101(7):1154-63. doi: 10.1002/jbm.b.32925. Epub 2013 Apr 6.


Transcutaneous treatment with vetdrop(®) sustains the adjacent cartilage in a microfracturing joint defect model in sheep.

Sidler M, Fouché N, Meth I, von Hahn F, von Rechenberg B, Kronen P.

Open Orthop J. 2013;7:57-66. doi: 10.2174/1874325001307010057. Epub 2013 Mar 5.


Experimentally induced cam impingement in the sheep hip.

Siebenrock KA, Fiechter R, Tannast M, Mamisch TC, von Rechenberg B.

J Orthop Res. 2013 Apr;31(4):580-7. doi: 10.1002/jor.22273. Epub 2012 Nov 28.


Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells.

Waselau M, Patrikoski M, Juntunen M, Kujala K, Kääriäinen M, Kuokkanen H, Sándor GK, Vapaavuori O, Suuronen R, Mannerström B, von Rechenberg B, Miettinen S.

J Tissue Eng. 2012;3(1):2041731412467789. doi: 10.1177/2041731412467789. Epub 2012 Nov 23.


The dynamisation of locking plate osteosynthesis by means of dynamic locking screws (DLS)-an experimental study in sheep.

Plecko M, Lagerpusch N, Andermatt D, Frigg R, Koch R, Sidler M, Kronen P, Klein K, Nuss K, Bürki A, Ferguson SJ, Stoeckle U, Auer JA, von Rechenberg B.

Injury. 2013 Oct;44(10):1346-57. doi: 10.1016/j.injury.2012.10.022. Epub 2012 Nov 24.


Rotator cuff muscles lose responsiveness to anabolic steroids after tendon tear and musculotendinous retraction: an experimental study in sheep.

Gerber C, Meyer DC, Von Rechenberg B, Hoppeler H, Frigg R, Farshad M.

Am J Sports Med. 2012 Nov;40(11):2454-61. doi: 10.1177/0363546512460646. Epub 2012 Sep 28.


Correction of metabolic acidosis with potassium citrate in renal transplant patients and its effect on bone quality.

Starke A, Corsenca A, Kohler T, Knubben J, Kraenzlin M, Uebelhart D, Wüthrich RP, von Rechenberg B, Müller R, Ambühl PM.

Clin J Am Soc Nephrol. 2012 Sep;7(9):1461-72. Epub 2012 Jul 5.

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