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Items: 1 to 50 of 103

1.

Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases.

Khadka N, Farquhar ER, Hill HE, Shi W, von Lintig J, Kiser PD.

J Biol Chem. 2019 Jul 5;294(27):10596-10606. doi: 10.1074/jbc.RA119.007535. Epub 2019 May 28.

PMID:
31138651
2.

Characterization of the novel role of NinaB orthologs from Bombyx mori and Tribolium castaneum.

Chai C, Xu X, Sun W, Zhang F, Ye C, Ding G, Li J, Zhong G, Xiao W, Liu B, von Lintig J, Lu C.

Insect Biochem Mol Biol. 2019 Jun;109:106-115. doi: 10.1016/j.ibmb.2019.03.004. Epub 2019 Mar 11.

PMID:
30871993
3.

News and views about carotenoids: Red-hot and true.

von Lintig J, Eggersdorfer M, Wyss A.

Arch Biochem Biophys. 2018 Nov 1;657:74-77. doi: 10.1016/j.abb.2018.09.010. Epub 2018 Sep 15. No abstract available.

PMID:
30227112
4.

Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.

Sui X, Farquhar ER, Hill HE, von Lintig J, Shi W, Kiser PD.

J Biol Inorg Chem. 2018 Aug;23(6):887-901. doi: 10.1007/s00775-018-1586-0. Epub 2018 Jun 26.

5.

The Biochemical Basis of Vitamin A Production from the Asymmetric Carotenoid β-Cryptoxanthin.

Kelly ME, Ramkumar S, Sun W, Colon Ortiz C, Kiser PD, Golczak M, von Lintig J.

ACS Chem Biol. 2018 Aug 17;13(8):2121-2129. doi: 10.1021/acschembio.8b00290. Epub 2018 Jun 15.

6.

Protective role of carotenoids in the visual cycle.

Widjaja-Adhi MAK, Ramkumar S, von Lintig J.

FASEB J. 2018 Jun 8:fj201800467R. doi: 10.1096/fj.201800467R. [Epub ahead of print]

PMID:
29882710
7.

Dietary vitamin A impacts DNA methylation patterns of adipogenesis-related genes in suckling rats.

Arreguín A, Ribot J, Mušinović H, von Lintig J, Palou A, Bonet ML.

Arch Biochem Biophys. 2018 Jul 15;650:75-84. doi: 10.1016/j.abb.2018.05.009. Epub 2018 May 11.

PMID:
29758201
8.

Tomato Powder Inhibits Hepatic Steatosis and Inflammation Potentially Through Restoring SIRT1 Activity and Adiponectin Function Independent of Carotenoid Cleavage Enzymes in Mice.

Li CC, Liu C, Fu M, Hu KQ, Aizawa K, Takahashi S, Hiroyuki S, Cheng J, von Lintig J, Wang XD.

Mol Nutr Food Res. 2018 Apr;62(8):e1700738. doi: 10.1002/mnfr.201700738. Epub 2018 Mar 22.

PMID:
29266812
9.

Transcription factor ISX mediates the cross talk between diet and immunity.

Widjaja-Adhi MAK, Palczewski G, Dale K, Knauss EA, Kelly ME, Golczak M, Levine AD, von Lintig J.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11530-11535. doi: 10.1073/pnas.1714963114. Epub 2017 Oct 9.

10.

Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.

Pyakurel A, Balmer D, Saba-El-Leil MK, Kizilyaprak C, Daraspe J, Humbel BM, Voisin L, Le YZ, von Lintig J, Meloche S, Roduit R.

Mol Cell Biol. 2017 Nov 28;37(24). pii: e00295-17. doi: 10.1128/MCB.00295-17. Print 2017 Dec 15.

11.

Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center.

Sui X, Weitz AC, Farquhar ER, Badiee M, Banerjee S, von Lintig J, Tochtrop GP, Palczewski K, Hendrich MP, Kiser PD.

Biochemistry. 2017 Jun 6;56(22):2836-2852. doi: 10.1021/acs.biochem.7b00251. Epub 2017 May 19.

12.

Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.

Xu M, Xie YA, Abouzeid H, Gordon CT, Fiorentino A, Sun Z, Lehman A, Osman IS, Dharmat R, Riveiro-Alvarez R, Bapst-Wicht L, Babino D, Arno G, Busetto V, Zhao L, Li H, Lopez-Martinez MA, Azevedo LF, Hubert L, Pontikos N, Eblimit A, Lorda-Sanchez I, Kheir V, Plagnol V, Oufadem M, Soens ZT, Yang L, Bole-Feysot C, Pfundt R, Allaman-Pillet N, Nitschké P, Cheetham ME, Lyonnet S, Agrawal SA, Li H, Pinton G, Michaelides M, Besmond C, Li Y, Yuan Z, von Lintig J, Webster AR, Le Hir H, Stoilov P; UK Inherited Retinal Dystrophy Consortium, Amiel J, Hardcastle AJ, Ayuso C, Sui R, Chen R, Allikmets R, Schorderet DF.

Am J Hum Genet. 2017 Apr 6;100(4):592-604. doi: 10.1016/j.ajhg.2017.02.008. Epub 2017 Mar 9.

13.

Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice.

Wu L, Guo X, Hartson SD, Davis MA, He H, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, von Lintig J, Lin D.

Mol Nutr Food Res. 2017 May;61(5). doi: 10.1002/mnfr.201600576. Epub 2017 Feb 9.

14.

Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family.

Hofmann L, Tsybovsky Y, Alexander NS, Babino D, Leung NY, Montell C, Banerjee S, von Lintig J, Palczewski K.

Biochemistry. 2016 Nov 29;55(47):6545-6557. Epub 2016 Nov 16.

15.

Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism.

Palczewski G, Widjaja-Adhi MA, Amengual J, Golczak M, von Lintig J.

J Lipid Res. 2016 Sep;57(9):1684-95. doi: 10.1194/jlr.M069021. Epub 2016 Jul 7.

16.

Transport of vitamin A across blood-tissue barriers is facilitated by STRA6.

Kelly M, Widjaja-Adhi MA, Palczewski G, von Lintig J.

FASEB J. 2016 Aug;30(8):2985-95. doi: 10.1096/fj.201600446R. Epub 2016 May 17.

17.

The Biochemical Basis of Vitamin A3 Production in Arthropod Vision.

Babino D, Golczak M, Kiser PD, Wyss A, Palczewski K, von Lintig J.

ACS Chem Biol. 2016 Apr 15;11(4):1049-57. doi: 10.1021/acschembio.5b00967. Epub 2016 Feb 2.

18.

Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.

Chen H, Babino D, Schoenbichler SA, Arkhipova V, Töchterle S, Martin F, Huck CW, von Lintig J, Meyer D.

PLoS One. 2015 Nov 30;10(11):e0143825. doi: 10.1371/journal.pone.0143825. eCollection 2015.

19.

Utilization of Dioxygen by Carotenoid Cleavage Oxygenases.

Sui X, Golczak M, Zhang J, Kleinberg KA, von Lintig J, Palczewski K, Kiser PD.

J Biol Chem. 2015 Dec 18;290(51):30212-23. doi: 10.1074/jbc.M115.696799. Epub 2015 Oct 23.

20.

STRA6: role in cellular retinol uptake and efflux.

Kelly M, von Lintig J.

Hepatobiliary Surg Nutr. 2015 Aug;4(4):229-42. doi: 10.3978/j.issn.2304-3881.2015.01.12. Review.

21.

Characterization of the Role of β-Carotene 9,10-Dioxygenase in Macular Pigment Metabolism.

Babino D, Palczewski G, Widjaja-Adhi MA, Kiser PD, Golczak M, von Lintig J.

J Biol Chem. 2015 Oct 9;290(41):24844-57. doi: 10.1074/jbc.M115.668822. Epub 2015 Aug 25.

22.

Retinylamine Benefits Early Diabetic Retinopathy in Mice.

Liu H, Tang J, Du Y, Lee CA, Golczak M, Muthusamy A, Antonetti DA, Veenstra AA, Amengual J, von Lintig J, Palczewski K, Kern TS.

J Biol Chem. 2015 Aug 28;290(35):21568-79. doi: 10.1074/jbc.M115.655555. Epub 2015 Jul 2.

23.

A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption.

Widjaja-Adhi MA, Lobo GP, Golczak M, Von Lintig J.

Hum Mol Genet. 2015 Jun 1;24(11):3206-19. doi: 10.1093/hmg/ddv072. Epub 2015 Feb 20.

24.

Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice.

Ip BC, Liu C, Lichtenstein AH, von Lintig J, Wang XD.

J Nutr. 2015 Feb;145(2):268-76. doi: 10.3945/jn.114.200238. Epub 2014 Dec 10.

25.

The role of 11-cis-retinyl esters in vertebrate cone vision.

Babino D, Perkins BD, Kindermann A, Oberhauser V, von Lintig J.

FASEB J. 2015 Jan;29(1):216-26. doi: 10.1096/fj.14-261693. Epub 2014 Oct 17.

26.

Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice.

Ip BC, Liu C, Ausman LM, von Lintig J, Wang XD.

Cancer Prev Res (Phila). 2014 Dec;7(12):1219-27. doi: 10.1158/1940-6207.CAPR-14-0154. Epub 2014 Oct 7.

27.

β-Carotene during the suckling period is absorbed intact and induces retinoic acid dependent responses similar to preformed vitamin A in intestine and liver, but not adipose tissue of young rats.

Mušinović H, Bonet ML, Granados N, Amengual J, von Lintig J, Ribot J, Palou A.

Mol Nutr Food Res. 2014 Nov;58(11):2157-65. doi: 10.1002/mnfr.201400457. Epub 2014 Sep 22.

PMID:
25164272
28.

A mouse model for studying cone photoreceptor pathologies.

Samardzija M, Caprara C, Heynen SR, Willcox DeParis S, Meneau I, Traber G, Agca C, von Lintig J, Grimm C.

Invest Ophthalmol Vis Sci. 2014 Jul 17;55(8):5304-13. doi: 10.1167/iovs.14-14789.

PMID:
25034607
29.

Evidence for compartmentalization of mammalian carotenoid metabolism.

Palczewski G, Amengual J, Hoppel CL, von Lintig J.

FASEB J. 2014 Oct;28(10):4457-69. doi: 10.1096/fj.14-252411. Epub 2014 Jul 7.

30.

STRA6 is critical for cellular vitamin A uptake and homeostasis.

Amengual J, Zhang N, Kemerer M, Maeda T, Palczewski K, Von Lintig J.

Hum Mol Genet. 2014 Oct 15;23(20):5402-17. doi: 10.1093/hmg/ddu258. Epub 2014 May 22.

31.

Analysis of carotenoid isomerase activity in a prototypical carotenoid cleavage enzyme, apocarotenoid oxygenase (ACO).

Sui X, Kiser PD, Che T, Carey PR, Golczak M, Shi W, von Lintig J, Palczewski K.

J Biol Chem. 2014 May 2;289(18):12286-99. doi: 10.1074/jbc.M114.552836. Epub 2014 Mar 19.

32.

Two carotenoid oxygenases contribute to mammalian provitamin A metabolism.

Amengual J, Widjaja-Adhi MA, Rodriguez-Santiago S, Hessel S, Golczak M, Palczewski K, von Lintig J.

J Biol Chem. 2013 Nov 22;288(47):34081-96. doi: 10.1074/jbc.M113.501049. Epub 2013 Oct 8.

33.

Carotenoids.

von Lintig J, Sies H.

Arch Biochem Biophys. 2013 Nov 15;539(2):99-101. doi: 10.1016/j.abb.2013.09.014. Epub 2013 Sep 25. No abstract available.

PMID:
24076362
34.

Diabetes-induced impairment in visual function in mice: contributions of p38 MAPK, rage, leukocytes, and aldose reductase.

Lee CA, Li G, Patel MD, Petrash JM, Benetz BA, Veenstra A, Amengual J, von Lintig J, Burant CJ, Tang J, Kern TS.

Invest Ophthalmol Vis Sci. 2014 May 2;55(5):2904-10. doi: 10.1167/iovs.13-11659.

35.

Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme.

Kowatz T, Babino D, Kiser P, Palczewski K, von Lintig J.

Arch Biochem Biophys. 2013 Nov 15;539(2):214-22. doi: 10.1016/j.abb.2013.05.007. Epub 2013 May 29.

36.

Genetic ablation of the fatty acid-binding protein FABP5 suppresses HER2-induced mammary tumorigenesis.

Levi L, Lobo G, Doud MK, von Lintig J, Seachrist D, Tochtrop GP, Noy N.

Cancer Res. 2013 Aug 1;73(15):4770-80. doi: 10.1158/0008-5472.CAN-13-0384. Epub 2013 May 30.

37.

Identification of nonvisual photomotor response cells in the vertebrate hindbrain.

Kokel D, Dunn TW, Ahrens MB, Alshut R, Cheung CY, Saint-Amant L, Bruni G, Mateus R, van Ham TJ, Shiraki T, Fukada Y, Kojima D, Yeh JR, Mikut R, von Lintig J, Engert F, Peterson RT.

J Neurosci. 2013 Feb 27;33(9):3834-43. doi: 10.1523/JNEUROSCI.3689-12.2013.

38.

Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.

Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J.

J Biol Chem. 2013 Mar 29;288(13):9017-27. doi: 10.1074/jbc.M112.444240. Epub 2013 Feb 7.

39.

Vitamin A supplementation in early life affects later response to an obesogenic diet in rats.

Granados N, Amengual J, Ribot J, Musinovic H, Ceresi E, von Lintig J, Palou A, Bonet ML.

Int J Obes (Lond). 2013 Sep;37(9):1169-76. doi: 10.1038/ijo.2012.190. Epub 2012 Dec 4.

PMID:
23207406
40.

Provitamin A metabolism and functions in mammalian biology.

von Lintig J.

Am J Clin Nutr. 2012 Nov;96(5):1234S-44S. doi: 10.3945/ajcn.112.034629. Epub 2012 Oct 10. Review.

41.

BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway.

Lobo GP, Isken A, Hoff S, Babino D, von Lintig J.

Development. 2012 Aug;139(16):2966-77. doi: 10.1242/dev.079632. Epub 2012 Jul 4.

42.

Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein.

Amengual J, Golczak M, Palczewski K, von Lintig J.

J Biol Chem. 2012 Jul 13;287(29):24216-27. doi: 10.1074/jbc.M112.353979. Epub 2012 May 27.

43.

The Drosophila visual cycle and de novo chromophore synthesis depends on rdhB.

Wang X, Wang T, Ni JD, von Lintig J, Montell C.

J Neurosci. 2012 Mar 7;32(10):3485-91. doi: 10.1523/JNEUROSCI.5350-11.2012.

44.

Differential expression of the demosponge (Suberites domuncula) carotenoid oxygenases in response to light: protection mechanism against the self-produced toxic protein (Suberitine).

Müller WE, Wang X, Binder M, von Lintig J, Wiens M, Schröder HC.

Mar Drugs. 2012 Jan;10(1):177-99. doi: 10.3390/md10010177. Epub 2012 Jan 18.

45.

Metabolism of carotenoids and retinoids related to vision.

von Lintig J.

J Biol Chem. 2012 Jan 13;287(3):1627-34. doi: 10.1074/jbc.R111.303990. Epub 2011 Nov 10. Review.

46.

Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1.

Müller WE, Binder M, von Lintig J, Guo YW, Wang X, Kaandorp JA, Wiens M, Schröder HC.

Biochim Biophys Acta. 2011 Dec;1810(12):1178-94. doi: 10.1016/j.bbagen.2011.09.006. Epub 2011 Sep 16.

PMID:
21952113
47.

Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis.

Maeda T, Perusek L, Amengual J, Babino D, Palczewski K, von Lintig J.

Mol Pharmacol. 2011 Nov;80(5):943-52. doi: 10.1124/mol.111.074732. Epub 2011 Aug 23.

48.

Gene expression response of mouse lung, liver and white adipose tissue to β-carotene supplementation, knockout of Bcmo1 and sex.

van Helden YG, Godschalk RW, von Lintig J, Lietz G, Landrier JF, Bonet ML, van Schooten FJ, Keijer J.

Mol Nutr Food Res. 2011 Oct;55(10):1466-74. doi: 10.1002/mnfr.201100194. Epub 2011 Jul 19. Erratum in: Mol Nutr Food Res. 2018 Apr;62(8):e1870051.

PMID:
21770050
49.

Beta-carotene reduces body adiposity of mice via BCMO1.

Amengual J, Gouranton E, van Helden YG, Hessel S, Ribot J, Kramer E, Kiec-Wilk B, Razny U, Lietz G, Wyss A, Dembinska-Kiec A, Palou A, Keijer J, Landrier JF, Bonet ML, von Lintig J.

PLoS One. 2011;6(6):e20644. doi: 10.1371/journal.pone.0020644. Epub 2011 Jun 1.

50.

Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis.

Lobo GP, Amengual J, Palczewski G, Babino D, von Lintig J.

Biochim Biophys Acta. 2012 Jan;1821(1):78-87. doi: 10.1016/j.bbalip.2011.04.010. Epub 2011 May 4. Review.

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