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Items: 1 to 50 of 97

1.

Glutaraldehyde - A Subtle Tool in the Investigation of Healthy and Pathologic Red Blood Cells.

Abay A, Simionato G, Chachanidze R, Bogdanova A, Hertz L, Bianchi P, van den Akker E, von Lindern M, Leonetti M, Minetti G, Wagner C, Kaestner L.

Front Physiol. 2019 May 14;10:514. doi: 10.3389/fphys.2019.00514. eCollection 2019.

2.

The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation.

Cantú I, van de Werken HJG, Gillemans N, Stadhouders R, Heshusius S, Maas A, Esteghamat F, Ozgur Z, van IJcken WFJ, Grosveld F, von Lindern M, Philipsen S, van Dijk TB.

PLoS One. 2019 Mar 28;14(3):e0208659. doi: 10.1371/journal.pone.0208659. eCollection 2019.

3.

Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.

Lopez-Yrigoyen M, Yang CT, Fidanza A, Cassetta L, Taylor AH, McCahill A, Sellink E, von Lindern M, van den Akker E, Mountford JC, Pollard JW, Forrester LM.

Nat Commun. 2019 Feb 20;10(1):881. doi: 10.1038/s41467-019-08705-0.

4.

Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets.

van Oorschot R, Hansen M, Koornneef JM, Marneth AE, Bergevoet SM, van Bergen MGJM, van Alphen FPJ, van der Zwaan C, Martens JHA, Vermeulen M, Jansen PWTC, Baltissen MPA, Gorkom BAPL, Janssen H, Jansen JH, von Lindern M, Meijer AB, van den Akker E, van der Reijden BA.

Haematologica. 2019 Jul;104(7):1460-1472. doi: 10.3324/haematol.2018.194555. Epub 2019 Jan 17.

5.

Strap associates with Csde1 and affects expression of select Csde1-bound transcripts.

Moore KS, Yagci N, van Alphen F, Meijer AB, 't Hoen PAC, von Lindern M.

PLoS One. 2018 Aug 23;13(8):e0201690. doi: 10.1371/journal.pone.0201690. eCollection 2018.

6.

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific.

Nicolet BP, Engels S, Aglialoro F, van den Akker E, von Lindern M, Wolkers MC.

Nucleic Acids Res. 2018 Sep 19;46(16):8168-8180. doi: 10.1093/nar/gky721.

7.

RNA Binding Proteins and Regulation of mRNA Translation in Erythropoiesis.

Moore KS, von Lindern M.

Front Physiol. 2018 Jul 24;9:910. doi: 10.3389/fphys.2018.00910. eCollection 2018. Review.

8.

TGFBI Expressed by Bone Marrow Niche Cells and Hematopoietic Stem and Progenitor Cells Regulates Hematopoiesis.

Klamer SE, Dorland YL, Kleijer M, Geerts D, Lento WE, van der Schoot CE, von Lindern M, Voermans C.

Stem Cells Dev. 2018 Nov 1;27(21):1494-1506. doi: 10.1089/scd.2018.0124. Epub 2018 Sep 6.

9.

The Shape Shifting Story of Reticulocyte Maturation.

Ovchynnikova E, Aglialoro F, von Lindern M, van den Akker E.

Front Physiol. 2018 Jul 11;9:829. doi: 10.3389/fphys.2018.00829. eCollection 2018. Review.

10.

Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.

Salerno F, Engels S, van den Biggelaar M, van Alphen FPJ, Guislain A, Zhao W, Hodge DL, Bell SE, Medema JP, von Lindern M, Turner M, Young HA, Wolkers MC.

Nat Immunol. 2018 Aug;19(8):828-837. doi: 10.1038/s41590-018-0155-6. Epub 2018 Jul 9.

PMID:
29988089
11.

Efficient production of erythroid, megakaryocytic and myeloid cells, using single cell-derived iPSC colony differentiation.

Hansen M, Varga E, Aarts C, Wust T, Kuijpers T, von Lindern M, van den Akker E.

Stem Cell Res. 2018 May;29:232-244. doi: 10.1016/j.scr.2018.04.016. Epub 2018 Apr 28.

12.

Ribosome profiling uncovers selective mRNA translation associated with eIF2 phosphorylation in erythroid progenitors.

Paolini NA, Moore KS, di Summa FM, Fokkema IFAC, 't Hoen PAC, von Lindern M.

PLoS One. 2018 Apr 10;13(4):e0193790. doi: 10.1371/journal.pone.0193790. eCollection 2018.

13.

Csde1 binds transcripts involved in protein homeostasis and controls their expression in an erythroid cell line.

Moore KS, Yagci N, van Alphen F, Paolini NA, Horos R, Held NM, Houtkooper RH, van den Akker E, Meijer AB, 't Hoen PAC, von Lindern M.

Sci Rep. 2018 Feb 8;8(1):2628. doi: 10.1038/s41598-018-20518-7.

14.

Generation and characterization of human iPSC lines SANi001-A and SANi002-A from mobilized peripheral blood derived megakaryoblasts.

Hansen M, Varga E, Wüst T, Mellink C, van der Kevie-Kersemaekers AM, von Lindern M, van den Akker E.

Stem Cell Res. 2017 Dec;25:42-45. doi: 10.1016/j.scr.2017.10.002. Epub 2017 Oct 12.

15.

Generation and characterization of a human iPSC line SANi005-A containing the gray platelet associated heterozygous mutation p.Q287* in GFI1B.

Hansen M, Varga E, Wüst T, Mellink C, van der Kevie-Kersemaekers AM, Marneth AE, von Lindern M, van der Reijden B, van den Akker E.

Stem Cell Res. 2017 Dec;25:34-37. doi: 10.1016/j.scr.2017.10.008. Epub 2017 Oct 12.

16.

Generation of human erythroblast-derived iPSC line using episomal reprogramming system.

Varga E, Hansen M, Wüst T, von Lindern M, van den Akker E.

Stem Cell Res. 2017 Dec;25:30-33. doi: 10.1016/j.scr.2017.10.001. Epub 2017 Oct 12.

17.

Trichothiodystrophy causative TFIIEβ mutation affects transcription in highly differentiated tissue.

Theil AF, Mandemaker IK, van den Akker E, Swagemakers SMA, Raams A, Wüst T, Marteijn JA, Giltay JC, Colombijn RM, Moog U, Kotzaeridou U, Ghazvini M, von Lindern M, Hoeijmakers JHJ, Jaspers NGJ, van der Spek PJ, Vermeulen W.

Hum Mol Genet. 2017 Dec 1;26(23):4689-4698. doi: 10.1093/hmg/ddx351.

18.

Distinct PKC-mediated posttranscriptional events set cytokine production kinetics in CD8+ T cells.

Salerno F, Paolini NA, Stark R, von Lindern M, Wolkers MC.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9677-9682. doi: 10.1073/pnas.1704227114. Epub 2017 Aug 23.

19.

DARC extracellular domain remodeling in maturating reticulocytes explains Plasmodium vivax tropism.

Ovchynnikova E, Aglialoro F, Bentlage AEH, Vidarsson G, Salinas ND, von Lindern M, Tolia NH, van den Akker E.

Blood. 2017 Sep 21;130(12):1441-1444. doi: 10.1182/blood-2017-03-774364. Epub 2017 Jul 28.

20.

Generation and characterization of human iPSC line MML-6838-Cl2 from mobilized peripheral blood derived megakaryoblasts.

Hansen M, Varga E, Wüst T, Brouwer N, Beauchemin H, Mellink C, van der Kevie-Kersemaekers AM, Möröy T, van der Reijden B, von Lindern M, van den Akker E.

Stem Cell Res. 2017 Jan;18:26-28. doi: 10.1016/j.scr.2016.12.004. Epub 2016 Dec 10.

21.

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism.

Paolini NA, Attwood M, Sondalle SB, Vieira CMDS, van Adrichem AM, di Summa FM, O'Donohue MF, Gleizes PE, Rachuri S, Briggs JW, Fischer R, Ratcliffe PJ, Wlodarski MW, Houtkooper RH, von Lindern M, Kuijpers TW, Dinman JD, Baserga SJ, Cockman ME, MacInnes AW.

Am J Hum Genet. 2017 Mar 2;100(3):506-522. doi: 10.1016/j.ajhg.2017.01.034.

22.

Cdk6 contributes to cytoskeletal stability in erythroid cells.

Uras IZ, Scheicher RM, Kollmann K, Glösmann M, Prchal-Murphy M, Tigan AS, Fux DA, Altamura S, Neves J, Muckenthaler MU, Bennett KL, Kubicek S, Hinds PW, von Lindern M, Sexl V.

Haematologica. 2017 Jun;102(6):995-1005. doi: 10.3324/haematol.2016.159947. Epub 2017 Mar 2.

23.

Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia.

van Attekum MHA, Terpstra S, Slinger E, von Lindern M, Moerland PD, Jongejan A, Kater AP, Eldering E.

Oncogene. 2017 Jun 29;36(26):3651-3660. doi: 10.1038/onc.2016.515. Epub 2017 Feb 13.

24.

Different Balance of Wnt Signaling in Adult and Fetal Bone Marrow-Derived Mesenchymal Stromal Cells.

Paciejewska MM, Maijenburg MW, Gilissen C, Kleijer M, Vermeul K, Weijer K, Veltman JA, von Lindern M, van der Schoot CE, Voermans C.

Stem Cells Dev. 2016 Jun 15;25(12):934-47. doi: 10.1089/scd.2015.0263.

PMID:
27154244
25.

Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs.

In K, Zaini MA, Müller C, Warren AJ, von Lindern M, Calkhoven CF.

Nucleic Acids Res. 2016 May 19;44(9):4134-46. doi: 10.1093/nar/gkw005. Epub 2016 Jan 13.

26.

CD14+ cells from peripheral blood positively regulate hematopoietic stem and progenitor cell survival resulting in increased erythroid yield.

Heideveld E, Masiello F, Marra M, Esteghamat F, Yağcı N, von Lindern M, Migliaccio AR, van den Akker E.

Haematologica. 2015 Nov;100(11):1396-406. doi: 10.3324/haematol.2015.125492. Epub 2015 Aug 20.

27.

Selective mRNA translation in erythropoiesis.

Thiadens KA, von Lindern M.

Biochem Soc Trans. 2015 Jun;43(3):343-7. doi: 10.1042/BST20150009. Review.

PMID:
26009174
28.

Assessing the translational landscape of myogenic differentiation by ribosome profiling.

de Klerk E, Fokkema IF, Thiadens KA, Goeman JJ, Palmblad M, den Dunnen JT, von Lindern M, 't Hoen PA.

Nucleic Acids Res. 2015 May 19;43(9):4408-28. doi: 10.1093/nar/gkv281. Epub 2015 Apr 14.

29.

ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation.

Alemdehy MF, Haanstra JR, de Looper HW, van Strien PM, Verhagen-Oldenampsen J, Caljouw Y, Sanders MA, Hoogenboezem R, de Ru AH, Janssen GM, Smetsers SE, Bierings MB, van Veelen PA, von Lindern M, Touw IP, Erkeland SJ.

Blood. 2015 Jun 18;125(25):3937-48. doi: 10.1182/blood-2014-11-612507. Epub 2015 Mar 16.

30.

Transfusion-independent β(0)-thalassemia after bone marrow transplantation failure: proposed involvement of high parental HbF and an epigenetic mechanism.

Paciaroni K, Lucarelli G, Martelli F, Migliaccio AR, von Lindern M, Borg J, Gillemans N, van Dijk TB, Philipsen S.

Am J Blood Res. 2014 Sep 5;4(1):27-32. eCollection 2014.

31.

Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment.

Nieradka A, Ufer C, Thiadens K, Grech G, Horos R, van Coevorden-Hameete M, van den Akker E, Sofi S, Kuhn H, von Lindern M.

PLoS One. 2014 Sep 3;9(9):e104631. doi: 10.1371/journal.pone.0104631. eCollection 2014.

32.

MEIS1 regulates early erythroid and megakaryocytic cell fate.

Zeddies S, Jansen SB, di Summa F, Geerts D, Zwaginga JJ, van der Schoot CE, von Lindern M, Thijssen-Timmer DC.

Haematologica. 2014 Oct;99(10):1555-64. doi: 10.3324/haematol.2014.106567. Epub 2014 Aug 8.

33.

Red cell distribution width as predictor for mortality in critically ill patients.

Meynaar IA, Knook AH, Coolen S, Le H, Bos MM, van der Dijs F, von Lindern M, Steyerberg EW.

Neth J Med. 2013 Nov;71(9):488-93.

34.

BIGH3 modulates adhesion and migration of hematopoietic stem and progenitor cells.

Klamer SE, Kuijk CG, Hordijk PL, van der Schoot CE, von Lindern M, van Hennik PB, Voermans C.

Cell Adh Migr. 2013 Sep-Oct;7(5):434-49. doi: 10.4161/cam.26596. Epub 2013 Oct 8.

35.

Locus-specific proteomics by TChP: targeted chromatin purification.

Pourfarzad F, Aghajanirefah A, de Boer E, Ten Have S, Bryn van Dijk T, Kheradmandkia S, Stadhouders R, Thongjuea S, Soler E, Gillemans N, von Lindern M, Demmers J, Philipsen S, Grosveld F.

Cell Rep. 2013 Aug 15;4(3):589-600. doi: 10.1016/j.celrep.2013.07.004. Epub 2013 Aug 1.

36.

Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.

Esteghamat F, Gillemans N, Bilic I, van den Akker E, Cantù I, van Gent T, Klingmüller U, van Lom K, von Lindern M, Grosveld F, Bryn van Dijk T, Busslinger M, Philipsen S.

Blood. 2013 Mar 28;121(13):2553-62. doi: 10.1182/blood-2012-06-434530. Epub 2013 Jan 29.

37.

Abnormal properties of red blood cells suggest a role in the pathophysiology of Gaucher disease.

Franco M, Collec E, Connes P, van den Akker E, Billette de Villemeur T, Belmatoug N, von Lindern M, Ameziane N, Hermine O, Colin Y, Le Van Kim C, Mignot C.

Blood. 2013 Jan 17;121(3):546-55. doi: 10.1182/blood-2012-07-442467. Epub 2012 Dec 3.

38.

Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity.

Pourfarzad F, von Lindern M, Azarkeivan A, Hou J, Kia SK, Esteghamat F, van Ijcken W, Philipsen S, Najmabadi H, Grosveld F.

Haematologica. 2013 May;98(5):696-704. doi: 10.3324/haematol.2012.074492. Epub 2012 Oct 25.

39.

KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients.

Borg J, Phylactides M, Bartsakoulia M, Tafrali C, Lederer C, Felice AE, Papachatzopoulou A, Kourakli A, Stavrou EF, Christou S, Hou J, Karkabouna S, Lappa-Manakou C, Ozgur Z, van Ijcken W, von Lindern M, Grosveld FG, Georgitsi M, Kleanthous M, Philipsen S, Patrinos GP.

Pharmacogenomics. 2012 Oct;13(13):1487-500. doi: 10.2217/pgs.12.125.

PMID:
23057549
40.

Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia.

Horos R, von Lindern M.

Br J Haematol. 2012 Dec;159(5):514-27. doi: 10.1111/bjh.12058. Epub 2012 Sep 27. Review.

PMID:
23016900
41.

Loss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors.

Verhagen-Oldenampsen JH, Haanstra JR, van Strien PM, Valkhof M, Touw IP, von Lindern M.

Anemia. 2012;2012:783068. doi: 10.1155/2012/783068. Epub 2012 Jun 3.

42.

The role of translation initiation regulation in haematopoiesis.

Grech G, von Lindern M.

Comp Funct Genomics. 2012;2012:576540. doi: 10.1155/2012/576540. Epub 2012 May 9.

43.

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts.

Horos R, Ijspeert H, Pospisilova D, Sendtner R, Andrieu-Soler C, Taskesen E, Nieradka A, Cmejla R, Sendtner M, Touw IP, von Lindern M.

Blood. 2012 Jan 5;119(1):262-72. doi: 10.1182/blood-2011-06-358200. Epub 2011 Nov 4.

44.

The DNA binding factor Hmg20b is a repressor of erythroid differentiation.

Esteghamat F, van Dijk TB, Braun H, Dekker S, van der Linden R, Hou J, Fanis P, Demmers J, van IJcken W, Ozgür Z, Horos R, Pourfarzad F, von Lindern M, Philipsen S.

Haematologica. 2011 Sep;96(9):1252-60. doi: 10.3324/haematol.2011.045211. Epub 2011 May 23.

45.

Fetal globin expression is regulated by Friend of Prmt1.

van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S.

Blood. 2010 Nov 18;116(20):4349-52. doi: 10.1182/blood-2010-03-274399. Epub 2010 Aug 5.

46.

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin.

Borg J, Papadopoulos P, Georgitsi M, Gutiérrez L, Grech G, Fanis P, Phylactides M, Verkerk AJ, van der Spek PJ, Scerri CA, Cassar W, Galdies R, van Ijcken W, Ozgür Z, Gillemans N, Hou J, Bugeja M, Grosveld FG, von Lindern M, Felice AE, Patrinos GP, Philipsen S.

Nat Genet. 2010 Sep;42(9):801-5. doi: 10.1038/ng.630. Epub 2010 Aug 1.

47.

The miR-144/451 locus is required for erythroid homeostasis.

Rasmussen KD, Simmini S, Abreu-Goodger C, Bartonicek N, Di Giacomo M, Bilbao-Cortes D, Horos R, Von Lindern M, Enright AJ, O'Carroll D.

J Exp Med. 2010 Jul 5;207(7):1351-8. doi: 10.1084/jem.20100458. Epub 2010 May 31.

48.

EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence.

Kheradmand Kia S, Solaimani Kartalaei P, Farahbakhshian E, Pourfarzad F, von Lindern M, Verrijzer CP.

Epigenetics Chromatin. 2009 Dec 2;2(1):16. doi: 10.1186/1756-8935-2-16.

49.

Tissue-specific splicing factor gene expression signatures.

Grosso AR, Gomes AQ, Barbosa-Morais NL, Caldeira S, Thorne NP, Grech G, von Lindern M, Carmo-Fonseca M.

Nucleic Acids Res. 2008 Sep;36(15):4823-32. doi: 10.1093/nar/gkn463. Epub 2008 Jul 24.

50.

Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation.

Grech G, Blázquez-Domingo M, Kolbus A, Bakker WJ, Müllner EW, Beug H, von Lindern M.

Blood. 2008 Oct 1;112(7):2750-60. doi: 10.1182/blood-2008-01-133140. Epub 2008 Jul 14.

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