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Items: 1 to 50 of 61

1.

HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.

Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaay7205. doi: 10.1126/scitranslmed.aay7205.

PMID:
31915304
2.

Impact of EMpagliflozin on cardiac function and biomarkers of heart failure in patients with acute MYocardial infarction-The EMMY trial.

Tripolt NJ, Kolesnik E, Pferschy PN, Verheyen N, Ablasser K, Sailer S, Alber H, Berger R, Kaulfersch C, Leitner K, Lichtenauer M, Mader A, Moertl D, Oulhaj A, Reiter C, Rieder T, Saely CH, Siller-Matula J, Weidinger F, Zechner PM, von Lewinski D, Sourij H; EMMY study group.

Am Heart J. 2019 Dec 12;221:39-47. doi: 10.1016/j.ahj.2019.12.004. [Epub ahead of print]

PMID:
31901799
3.

Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.

Berulava T, Buchholz E, Elerdashvili V, Pena T, Islam MR, Lbik D, Mohamed BA, Renner A, von Lewinski D, Sacherer M, Bohnsack KE, Bohnsack MT, Jain G, Capece V, Cleve N, Burkhardt S, Hasenfuss G, Fischer A, Toischer K.

Eur J Heart Fail. 2019 Dec 17. doi: 10.1002/ejhf.1672. [Epub ahead of print]

PMID:
31849158
4.

Haemodynamic Balance in Acute and Advanced Heart Failure: An Expert Perspective on the Role of Levosimendan.

Agostoni P, Farmakis DT, García-Pinilla JM, Harjola VP, Karason K, von Lewinski D, Parissis J, Pollesello P, Pölzl G, Recio-Mayoral A, Reinecke A, Yerly P, Zima E.

Card Fail Rev. 2019 Nov 4;5(3):155-161. doi: 10.15420/cfr.2019.01.R1. eCollection 2019 Nov. Review.

5.

A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement.

Dangas GD, Tijssen JGP, Wöhrle J, Søndergaard L, Gilard M, Möllmann H, Makkar RR, Herrmann HC, Giustino G, Baldus S, De Backer O, Guimarães AHC, Gullestad L, Kini A, von Lewinski D, Mack M, Moreno R, Schäfer U, Seeger J, Tchétché D, Thomitzek K, Valgimigli M, Vranckx P, Welsh RC, Wildgoose P, Volkl AA, Zazula A, van Amsterdam RGM, Mehran R, Windecker S; GALILEO Investigators.

N Engl J Med. 2020 Jan 9;382(2):120-129. doi: 10.1056/NEJMoa1911425. Epub 2019 Nov 16.

PMID:
31733180
6.

A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus.

Farmakis D, Agostoni P, Baholli L, Bautin A, Comin-Colet J, Crespo-Leiro MG, Fedele F, García-Pinilla JM, Giannakoulas G, Grigioni F, Gruchała M, Gustafsson F, Harjola VP, Hasin T, Herpain A, Iliodromitis EK, Karason K, Kivikko M, Liaudet L, Ljubas-Maček J, Marini M, Masip J, Mebazaa A, Nikolaou M, Ostadal P, Põder P, Pollesello P, Polyzogopoulou E, Pölzl G, Tschope C, Varpula M, von Lewinski D, Vrtovec B, Yilmaz MB, Zima E, Parissis J.

Int J Cardiol. 2019 Dec 15;297:83-90. doi: 10.1016/j.ijcard.2019.09.005. Epub 2019 Sep 6.

7.

Effects of Serelaxin in Patients with Acute Heart Failure.

Metra M, Teerlink JR, Cotter G, Davison BA, Felker GM, Filippatos G, Greenberg BH, Pang PS, Ponikowski P, Voors AA, Adams KF, Anker SD, Arias-Mendoza A, Avendaño P, Bacal F, Böhm M, Bortman G, Cleland JGF, Cohen-Solal A, Crespo-Leiro MG, Dorobantu M, Echeverría LE, Ferrari R, Goland S, Goncalvesová E, Goudev A, Køber L, Lema-Osores J, Levy PD, McDonald K, Manga P, Merkely B, Mueller C, Pieske B, Silva-Cardoso J, Špinar J, Squire I, Stępińska J, Van Mieghem W, von Lewinski D, Wikström G, Yilmaz MB, Hagner N, Holbro T, Hua TA, Sabarwal SV, Severin T, Szecsödy P, Gimpelewicz C; RELAX-AHF-2 Committees Investigators.

N Engl J Med. 2019 Aug 22;381(8):716-726. doi: 10.1056/NEJMoa1801291.

PMID:
31433919
8.

Incidence, predictors, and prognosis of premature discontinuation or switch of prasugrel or ticagrelor: the ATLANTIS - SWITCH study.

Winter MP, von Lewinski D, Wallner M, Prüller F, Kolesnik E, Hengstenberg C, Siller-Matula JM.

Sci Rep. 2019 Jun 3;9(1):8194. doi: 10.1038/s41598-019-44673-7.

9.

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment.

Schanstra JP, Luong TT, Makridakis M, Van Linthout S, Lygirou V, Latosinska A, Alesutan I, Boehme B, Schelski N, Von Lewinski D, Mullen W, Nicklin S, Delles C, Feuillet G, Denis C, Lang F, Pieske B, Bascands JL, Mischak H, Saulnier-Blache JS, Voelkl J, Vlahou A, Klein J.

JCI Insight. 2019 May 16;4(10). pii: 125638. doi: 10.1172/jci.insight.125638. eCollection 2019 May 16.

10.

Obstructive sleep apnea is associated with pulmonary artery thrombus load, disease severity, and survival in acute pulmonary embolism.

Geissenberger F, Schwarz F, Probst M, Haberl S, Parkhe A, Faul C, von Lewinski D, Kroencke T, Schwaiblmair M, von Scheidt W, Berghaus TM.

Clin Res Cardiol. 2020 Jan;109(1):13-21. doi: 10.1007/s00392-019-01479-x. Epub 2019 Apr 23.

PMID:
31016383
11.

Platelet reactivity patterns in patients treated with dual antiplatelet therapy.

Winter MP, Schneeweiss T, Cremer R, Biesinger B, Hengstenberg C, Prüller F, Wallner M, Kolesnik E, von Lewinski D, Lang IM, Siller-Matula JM.

Eur J Clin Invest. 2019 Mar 18:e13102. doi: 10.1111/eci.13102. [Epub ahead of print]

12.

Use of levosimendan in acute heart failure.

Harjola VP, Giannakoulas G, von Lewinski D, Matskeplishvili S, Mebazaa A, Papp Z, Schwinger RHG, Pollesello P, Parissis JT.

Eur Heart J Suppl. 2018 Dec;20(Suppl I):I2-I10. doi: 10.1093/eurheartj/suy039. Epub 2018 Dec 11.

13.

Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.

Koyani CN, Trummer C, Shrestha N, Scheruebel S, Bourgeois B, Plastira I, Kickmaier S, Sourij H, Rainer PP, Madl T, Sattler W, Pelzmann B, Malle E, von Lewinski D.

Front Physiol. 2018 Nov 14;9:1622. doi: 10.3389/fphys.2018.01622. eCollection 2018.

14.

Cangrelor Induces More Potent Platelet Inhibition without Increasing Bleeding in Resuscitated Patients.

Prüller F, Bis L, Milke OL, Fruhwald F, Pätzold S, Altmanninger-Sock S, Siller-Matula J, von Lewinski F, Ablasser K, Sacherer M, von Lewinski D.

J Clin Med. 2018 Nov 15;7(11). pii: E442. doi: 10.3390/jcm7110442.

15.

Diabetic Cardiomyopathy: Current and Future Therapies. Beyond Glycemic Control.

Borghetti G, von Lewinski D, Eaton DM, Sourij H, Houser SR, Wallner M.

Front Physiol. 2018 Oct 30;9:1514. doi: 10.3389/fphys.2018.01514. eCollection 2018. Review.

16.

Levosimendan in Acute and Advanced Heart Failure: an Expert Perspective on Posology and Therapeutic Application.

Bouchez S, Fedele F, Giannakoulas G, Gustafsson F, Harjola VP, Karason K, Kivikko M, von Lewinski D, Oliva F, Papp Z, Parissis J, Pollesello P, Pölzl G, Tschöpe C.

Cardiovasc Drugs Ther. 2018 Dec;32(6):617-624. doi: 10.1007/s10557-018-6838-2. Review.

17.

Revisiting the Diabetes-Heart Failure Connection.

Wallner M, Eaton DM, von Lewinski D, Sourij H.

Curr Diab Rep. 2018 Oct 20;18(12):134. doi: 10.1007/s11892-018-1116-z. Review.

18.

Heart rate-reducing therapy with add-on ivabradine and bisoprolol before coronary computed tomographic angiography in a fast-track ambulatory setting.

Muster V, Wallner M, Schmidt A, Kapl M, von Lewinski F, Rainer P, Reittner P, Tillich M, Brader P, Szolar DH, von Lewinski D.

J Int Med Res. 2018 Jun;46(6):2249-2257. doi: 10.1177/0300060518761302. Epub 2018 Apr 3.

19.

Thermic sealing in femoral catheterization: First experience with the Secure Device.

Sacherer M, Kolesnik E, von Lewinski F, Verheyen N, Brandner K, Wallner M, Eaton DM, Luha O, Zweiker R, von Lewinski D.

Cardiol J. 2019;26(3):233-240. doi: 10.5603/CJ.a2018.0035. Epub 2018 Apr 3.

20.

The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients.

Schneider C, Wallner M, Kolesnik E, Herbst V, Mächler H, Pichler M, von Lewinski D, Sedej S, Rainer PP.

Sci Rep. 2018 Mar 28;8(1):5295. doi: 10.1038/s41598-018-23630-w.

21.

Impaired aspirin-mediated platelet function inhibition in resuscitated patients with acute myocardial infarction treated with therapeutic hypothermia: a prospective, observational, non-randomized single-centre study.

Prüller F, Milke OL, Bis L, Fruhwald F, Scherr D, Eller P, Pätzold S, Altmanninger-Sock S, Rainer P, Siller-Matula J, von Lewinski D.

Ann Intensive Care. 2018 Feb 21;8(1):28. doi: 10.1186/s13613-018-0366-x.

22.

A Feline HFpEF Model with Pulmonary Hypertension and Compromised Pulmonary Function.

Wallner M, Eaton DM, Berretta RM, Borghetti G, Wu J, Baker ST, Feldsott EA, Sharp TE 3rd, Mohsin S, Oyama MA, von Lewinski D, Post H, Wolfson MR, Houser SR.

Sci Rep. 2017 Nov 29;7(1):16587. doi: 10.1038/s41598-017-15851-2.

23.

Revisiting the tryptophan-serotonin deficiency and the inflammatory hypotheses of major depression in a biopsychosocial approach.

Baranyi A, Amouzadeh-Ghadikolai O, von Lewinski D, Breitenecker RJ, Rothenhäusler HB, Robier C, Baranyi M, Theokas S, Meinitzer A.

PeerJ. 2017 Nov 2;5:e3968. doi: 10.7717/peerj.3968. eCollection 2017.

24.

In-Hospital Outcome Comparing Bivalirudin to Heparin in Real-World Primary Percutaneous Coronary Intervention.

Hasun M, Dörler J, Edlinger M, Alber H, Von Lewinski D, Eber B, Roithinger FX, Berger R, Siostrzonek P, Grimm G, Benzer W, Wintersteller W, Huber K, Schuchlenz H, Weidinger F; Austrian Acute PCI Investigators.

Am J Cardiol. 2017 Dec 15;120(12):2135-2140. doi: 10.1016/j.amjcard.2017.08.037. Epub 2017 Sep 20.

PMID:
29103603
25.

Implementation of buffy-coat-derived pooled platelet concentrates for internal quality control of light transmission aggregometry: a proof of concept study.

Prüller F, Rosskopf K, Mangge H, Mahla E, von Lewinski D, Weiss EC, Riegler A, Enko D.

J Thromb Haemost. 2017 Dec;15(12):2443-2450. doi: 10.1111/jth.13870. Epub 2017 Nov 22.

26.

Effect of eplerenone on markers of bone turnover in patients with primary hyperparathyroidism - The randomized, placebo-controlled EPATH trial.

Verheyen N, Grübler MR, Meinitzer A, Trummer C, Schwetz V, Amrein K, Dimai HP, März W, Catena C, von Lewinski D, Voelkl J, Alesutan I, Fahrleitner-Pammer A, Brussee H, Pilz S, Tomaschitz A.

Bone. 2017 Dec;105:212-217. doi: 10.1016/j.bone.2017.08.030. Epub 2017 Sep 14.

PMID:
28918310
27.

New Antihyperglycemic Drugs and Heart Failure: Synopsis of Basic and Clinical Data.

von Lewinski D, Kolesnik E, Wallner M, Resl M, Sourij H.

Biomed Res Int. 2017;2017:1253425. doi: 10.1155/2017/1253425. Epub 2017 Aug 15. Review.

28.

Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.

Koyani CN, Kolesnik E, Wölkart G, Shrestha N, Scheruebel S, Trummer C, Zorn-Pauly K, Hammer A, Lang P, Reicher H, Maechler H, Groschner K, Mayer B, Rainer PP, Sourij H, Sattler W, Malle E, Pelzmann B, von Lewinski D.

Biochem Pharmacol. 2017 Dec 1;145:64-80. doi: 10.1016/j.bcp.2017.08.021. Epub 2017 Aug 30.

29.

Plasma parathyroid hormone and cardiovascular disease in treatment-naive patients with primary hyperparathyroidism: The EPATH trial.

Wetzel J, Pilz S, Grübler MR, Fahrleitner-Pammer A, Dimai HP, von Lewinski D, Kolesnik E, Perl S, Trummer C, Schwetz V, Meinitzer A, Belyavskiy E, Völkl J, Catena C, Brandenburg V, März W, Pieske B, Brussee H, Tomaschitz A, Verheyen ND.

J Clin Hypertens (Greenwich). 2017 Nov;19(11):1173-1180. doi: 10.1111/jch.13064. Epub 2017 Aug 20.

30.

Role of STIM1 (Stromal Interaction Molecule 1) in Hypertrophy-Related Contractile Dysfunction.

Troupes CD, Wallner M, Borghetti G, Zhang C, Mohsin S, von Lewinski D, Berretta RM, Kubo H, Chen X, Soboloff J, Houser S.

Circ Res. 2017 Jul 7;121(2):125-136. doi: 10.1161/CIRCRESAHA.117.311094. Epub 2017 Jun 7.

31.

Repetitive use of levosimendan in advanced heart failure: need for stronger evidence in a field in dire need of a useful therapy.

Pölzl G, Altenberger J, Baholli L, Beltrán P, Borbély A, Comin-Colet J, Delgado JF, Fedele F, Fontana A, Fruhwald F, Giamouzis G, Giannakoulas G, Garcia-González MJ, Gustafsson F, Kaikkonen K, Kivikko M, Kubica J, von Lewinski D, Löfman I, Malfatto G, Manito N, Martínez-Sellés M, Masip J, Merkely B, Morandi F, Mølgaard H, Oliva F, Pantev E, Papp Z, Perna GP, Pfister R, Piazza V, Bover R, Rangel-Sousa D, Recio-Mayoral A, Reinecke A, Rieth A, Sarapohja T, Schmidt G, Seidel M, Störk S, Vrtovec B, Wikström G, Yerly P, Pollesello P.

Int J Cardiol. 2017 Sep 15;243:389-395. doi: 10.1016/j.ijcard.2017.05.081. Epub 2017 May 23. Review.

32.

Branched-Chain Amino Acids as New Biomarkers of Major Depression - A Novel Neurobiology of Mood Disorder.

Baranyi A, Amouzadeh-Ghadikolai O, von Lewinski D, Rothenhäusler HB, Theokas S, Robier C, Mangge H, Reicht G, Hlade P, Meinitzer A.

PLoS One. 2016 Aug 4;11(8):e0160542. doi: 10.1371/journal.pone.0160542. eCollection 2016.

33.

Staphylococcus lugdunensis Endocarditis in a 35-Year-Old Woman in Her 24th Week of Pregnancy.

Khafaga M, Kresoja KP, Urlesberger B, Knez I, Klaritsch P, Lumenta DB, Krause R, von Lewinski D.

Case Rep Obstet Gynecol. 2016;2016:7030382. doi: 10.1155/2016/7030382. Epub 2016 Mar 9.

34.

Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium.

Wallner M, Kolesnik E, Ablasser K, Khafaga M, Wakula P, Ljubojevic S, Thon-Gutschi EM, Sourij H, Kapl M, Edmunds NJ, Kuzmiski JB, Griffith DA, Knez I, Pieske B, von Lewinski D.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):365-75. doi: 10.1016/j.yjmcc.2015.09.018. Epub 2015 Oct 1.

PMID:
26432951
35.

Massive fistulization into the left ventricle of a transplanted heart.

Wallner M, Zweiker R, Maier R, Strunk D, von Lewinski D.

Herz. 2015 Mar;40 Suppl 1:56-8. doi: 10.1007/s00059-014-4077-2. Epub 2014 Apr 26. No abstract available.

PMID:
24763436
36.

Mild hypothermia attenuates circulatory and pulmonary dysfunction during experimental endotoxemia.

Schwarzl M, Seiler S, Wallner M, von Lewinski D, Huber S, Maechler H, Steendijk P, Zelzer S, Truschnig-Wilders M, Obermayer-Pietsch B, Lueger A, Pieske BM, Post H.

Crit Care Med. 2013 Dec;41(12):e401-10. doi: 10.1097/CCM.0b013e31829791da.

PMID:
23963130
37.

Bile acids induce arrhythmias in human atrial myocardium--implications for altered serum bile acid composition in patients with atrial fibrillation.

Rainer PP, Primessnig U, Harenkamp S, Doleschal B, Wallner M, Fauler G, Stojakovic T, Wachter R, Yates A, Groschner K, Trauner M, Pieske BM, von Lewinski D.

Heart. 2013 Nov;99(22):1685-92. doi: 10.1136/heartjnl-2013-304163. Epub 2013 Jul 26.

PMID:
23894089
38.

Relevance of stretch-induced phosphorylation of MAPK and p90rsk in human myocardium.

Kockskamper A, von Lewinski D, Zhu D, Kockskamper J, Khafaga M, Schmidt AG, Post H, Pieske B.

Front Biosci (Elite Ed). 2013 Jun 1;5:883-92.

PMID:
23747903
39.

Fungal endocarditis of a bioprosthetic aortic valve. Pharmacological treatment of a Candida parapsilosis endocarditis.

Wallner M, Steyer G, Krause R, Gstettner C, von Lewinski D.

Herz. 2013 Jun;38(4):431-4. doi: 10.1007/s00059-012-3715-9. Epub 2012 Dec 23.

PMID:
23263246
40.

Efficacy and safety of glucose control with Space GlucoseControl in the medical intensive care unit--an open clinical investigation.

Amrein K, Ellmerer M, Hovorka R, Kachel N, Fries H, von Lewinski D, Smolle K, Pieber TR, Plank J.

Diabetes Technol Ther. 2012 Aug;14(8):690-5. doi: 10.1089/dia.2012.0021. Epub 2012 Jun 13.

PMID:
22694176
41.

JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.

Sacherer M, Sedej S, Wakuła P, Wallner M, Vos MA, Kockskämper J, Stiegler P, Sereinigg M, von Lewinski D, Antoons G, Pieske BM, Heinzel FR; CONTICA investigators.

Br J Pharmacol. 2012 Oct;167(3):493-504. doi: 10.1111/j.1476-5381.2012.01995.x.

42.

Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes.

Rainer PP, Doleschal B, Kirk JA, Sivakumaran V, Saad Z, Groschner K, Maechler H, Hoefler G, Bauernhofer T, Samonigg H, Hutterer G, Kass DA, Pieske B, von Lewinski D, Pichler M.

BJU Int. 2012 Nov;110(10):1455-62. doi: 10.1111/j.1464-410X.2012.11134.x. Epub 2012 Apr 17.

43.

AMPK - Activated Protein Kinase and its Role in Energy Metabolism of the Heart.

Heidrich F, Schotola H, Popov AF, Sohns C, Schuenemann J, Friedrich M, Coskun KO, von Lewinski D, Hinz J, Bauer M, Mokashi SA, Sossalla S, Schmitto JD.

Curr Cardiol Rev. 2010 Nov;6(4):337-42. doi: 10.2174/157340310793566073.

44.

Stretch-induced Slow Force Response in Mammalian Ventricular Myocardium.

von Lewinski D, Kockskämper J, Pieske B.

In: Kamkin A, Kiseleva I, editors. Mechanosensitivity in Cells and Tissues. Moscow: Academia; 2005.

45.

Serotonin syndrome with severe hyperthermia after ingestion of tranylcypromine combined with serotonin reuptake inhibitors and tyramine-rich food in a case of suicide.

Degner D, Porzig J, Rüther E, von Lewinski D.

Pharmacopsychiatry. 2010 Nov;43(7):284-5. doi: 10.1055/s-0030-1263176. Epub 2010 Sep 9. No abstract available.

PMID:
20830665
46.

Functional effects of glucose transporters in human ventricular myocardium.

von Lewinski D, Gasser R, Rainer PP, Huber MS, Wilhelm B, Roessl U, Haas T, Wasler A, Grimm M, Bisping E, Pieske B.

Eur J Heart Fail. 2010 Feb;12(2):106-13. doi: 10.1093/eurjhf/hfp191.

47.

Glucose-transporter-mediated positive inotropic effects in human myocardium of diabetic and nondiabetic patients.

von Lewinski D, Rainer PP, Gasser R, Huber MS, Khafaga M, Wilhelm B, Haas T, Mächler H, Rössl U, Pieske B.

Metabolism. 2010 Jul;59(7):1020-8. doi: 10.1016/j.metabol.2009.10.025. Epub 2009 Dec 31.

PMID:
20045149
48.

Reduced stretch-induced force response in failing human myocardium caused by impaired Na(+)-contraction coupling.

von Lewinski D, Kockskämper J, Zhu D, Post H, Elgner A, Pieske B.

Circ Heart Fail. 2009 Jan;2(1):47-55. doi: 10.1161/CIRCHEARTFAILURE.108.794065.

PMID:
19808315
49.

Direct pro-arrhythmogenic effects of angiotensin II can be suppressed by AT1 receptor blockade in human atrial myocardium.

von Lewinski D, Kockskämper J, Rübertus SU, Zhu D, Schmitto JD, Schöndube FA, Hasenfuss G, Pieske B.

Eur J Heart Fail. 2008 Dec;10(12):1172-6. doi: 10.1016/j.ejheart.2008.09.014. Epub 2008 Nov 7.

50.

Frequency-dependence of the slow force response.

von Lewinski D, Zhu D, Khafaga M, Kockskamper J, Maier LS, Hasenfuss G, Pieske B.

Front Biosci. 2008 May 1;13:7202-9.

PMID:
18508728

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