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Items: 50

1.

Glycans and Glycan-Binding Proteins in Atherosclerosis.

Eckardt V, Weber C, von Hundelshausen P.

Thromb Haemost. 2019 Aug;119(8):1265-1273. doi: 10.1055/s-0039-1692720. Epub 2019 Jul 2.

PMID:
31266083
2.

PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.

Bianchini M, Duchêne J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA.

Sci Immunol. 2019 Jun 21;4(36). pii: eaar3054. doi: 10.1126/sciimmunol.aar3054.

PMID:
31227596
3.

CANTOS Trial Validates the Inflammatory Pathogenesis of Atherosclerosis: Setting the Stage for a New Chapter in Therapeutic Targeting.

Weber C, von Hundelshausen P.

Circ Res. 2017 Oct 27;121(10):1119-1121. doi: 10.1161/CIRCRESAHA.117.311984. Review. No abstract available.

PMID:
29074528
4.

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaah6650. doi: 10.1126/scitranslmed.aah6650.

PMID:
28381538
5.

Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice.

Zhao Z, Vajen T, Karshovska E, Dickhout A, Schmitt MM, Megens RTA, von Hundelshausen P, Koeppel TA, Hackeng TM, Weber C, Koenen RR.

J Cell Mol Med. 2017 Aug;21(8):1523-1531. doi: 10.1111/jcmm.13083. Epub 2017 Feb 17.

6.

Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.

Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O.

EBioMedicine. 2017 Feb;16:204-211. doi: 10.1016/j.ebiom.2017.01.006. Epub 2017 Jan 7.

7.

Probing Functional Heteromeric Chemokine Protein-Protein Interactions through Conformation-Assisted Oxime Ligation.

Agten SM, Koenen RR, Ippel H, Eckardt V, von Hundelshausen P, Mayo KH, Weber C, Hackeng TM.

Angew Chem Int Ed Engl. 2016 Nov 21;55(48):14963-14966. doi: 10.1002/anie.201607036. Epub 2016 Oct 27.

8.

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5.

Alard JE, Ortega-Gomez A, Wichapong K, Bongiovanni D, Horckmans M, Megens RT, Leoni G, Ferraro B, Rossaint J, Paulin N, Ng J, Ippel H, Suylen D, Hinkel R, Blanchet X, Gaillard F, D'Amico M, von Hundelshausen P, Zarbock A, Scheiermann C, Hackeng TM, Steffens S, Kupatt C, Nicolaes GA, Weber C, Soehnlein O.

Sci Transl Med. 2015 Dec 9;7(317):317ra196. doi: 10.1126/scitranslmed.aad5330.

PMID:
26659570
9.

Immune-mediated and lipid-mediated platelet function in atherosclerosis.

Ahmadsei M, Lievens D, Weber C, von Hundelshausen P, Gerdes N.

Curr Opin Lipidol. 2015 Oct;26(5):438-48. doi: 10.1097/MOL.0000000000000212. Review.

PMID:
26270811
10.

Platelet-derived chemokines in atherosclerosis.

Duchene J, von Hundelshausen P.

Hamostaseologie. 2015;35(2):137-41. doi: 10.5482/HAMO-14-11-0058. Epub 2015 Jan 16. Review.

PMID:
25592448
11.

Platelet-derived MIF: a novel platelet chemokine with distinct recruitment properties.

Wirtz TH, Tillmann S, Strüßmann T, Kraemer S, Heemskerk JW, Grottke O, Gawaz M, von Hundelshausen P, Bernhagen J.

Atherosclerosis. 2015 Mar;239(1):1-10. doi: 10.1016/j.atherosclerosis.2014.12.039. Epub 2014 Dec 24.

PMID:
25561410
12.

Recurrent spontaneous coronary dissections in a patient with a de novo fibrillin-1 mutation without Marfan syndrome.

von Hundelshausen P, Oexle K, Bidzhekov K, Schmitt MM, Hristov M, Blanchet X, Kaemmerer H, Matyas G, Meitinger T, Weber C.

Thromb Haemost. 2015 Mar;113(3):668-70. doi: 10.1160/TH14-11-0913. Epub 2014 Dec 18. No abstract available.

PMID:
25519456
13.

Hyperreactivity of junctional adhesion molecule A-deficient platelets accelerates atherosclerosis in hyperlipidemic mice.

Karshovska E, Zhao Z, Blanchet X, Schmitt MM, Bidzhekov K, Soehnlein O, von Hundelshausen P, Mattheij NJ, Cosemans JM, Megens RT, Koeppel TA, Schober A, Hackeng TM, Weber C, Koenen RR.

Circ Res. 2015 Feb 13;116(4):587-99. doi: 10.1161/CIRCRESAHA.116.304035. Epub 2014 Dec 3.

PMID:
25472975
14.

Inflammatory role and prognostic value of platelet chemokines in acute coronary syndrome.

Blanchet X, Cesarek K, Brandt J, Herwald H, Teupser D, Küchenhoff H, Karshovska E, Mause SF, Siess W, Wasmuth H, Soehnlein O, Koenen RR, Weber C, von Hundelshausen P.

Thromb Haemost. 2014 Dec;112(6):1277-87. doi: 10.1160/TH14-02-0139. Epub 2014 Aug 28.

PMID:
25183015
15.

Platelets and their chemokines in atherosclerosis-clinical applications.

von Hundelshausen P, Schmitt MM.

Front Physiol. 2014 Aug 8;5:294. doi: 10.3389/fphys.2014.00294. eCollection 2014. Review.

16.

Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.

Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit MJ, Blanchet X, von Hundelshausen P, Weber C, Forssmann WG, Henschler R.

Stem Cells Dev. 2014 Aug 15;23(16):1959-74. doi: 10.1089/scd.2013.0524. Epub 2014 May 27.

17.

Platelet-derived PF4 reduces neutrophil apoptosis following arterial occlusion.

Hartwig H, Drechsler M, Lievens D, Kramp B, von Hundelshausen P, Lutgens E, Weber C, Döring Y, Soehnlein O.

Thromb Haemost. 2014 Mar 3;111(3):562-4. doi: 10.1160/TH13-08-0699. Epub 2013 Nov 21. No abstract available.

PMID:
24258616
18.

[Chronic inflammation and atherosclerosis].

von Hundelshausen P, Weber C.

Dtsch Med Wochenschr. 2013 Sep;138(37):1839-44. doi: 10.1055/s-0033-1349426. Epub 2013 Sep 4. Review. German.

PMID:
24006166
19.

Exchange of extracellular domains of CCR1 and CCR5 reveals confined functions in CCL5-mediated cell recruitment.

Kramp BK, Megens RT, Sarabi A, Winkler S, Projahn D, Weber C, Koenen RR, von Hundelshausen P.

Thromb Haemost. 2013 Oct;110(4):795-806. doi: 10.1160/TH13-05-0420. Epub 2013 Aug 8.

PMID:
23925484
20.

Platelets are a previously unrecognised source of MIF.

Strüßmann T, Tillmann S, Wirtz T, Bucala R, von Hundelshausen P, Bernhagen J.

Thromb Haemost. 2013 Nov;110(5):1004-13. doi: 10.1160/TH13-01-0049. Epub 2013 Jul 11.

PMID:
23846621
21.

Platelet chemokines in health and disease.

Karshovska E, Weber C, von Hundelshausen P.

Thromb Haemost. 2013 Nov;110(5):894-902. doi: 10.1160/TH13-04-0341. Epub 2013 Jun 20. Review.

PMID:
23783401
22.

Neutrophil-derived cathelicidin promotes adhesion of classical monocytes.

Wantha S, Alard JE, Megens RT, van der Does AM, Döring Y, Drechsler M, Pham CT, Wang MW, Wang JM, Gallo RL, von Hundelshausen P, Lindbom L, Hackeng T, Weber C, Soehnlein O.

Circ Res. 2013 Mar 1;112(5):792-801. doi: 10.1161/CIRCRESAHA.112.300666. Epub 2013 Jan 2.

23.

Touch of chemokines.

Blanchet X, Langer M, Weber C, Koenen RR, von Hundelshausen P.

Front Immunol. 2012 Jul 12;3:175. doi: 10.3389/fimmu.2012.00175. eCollection 2012.

24.

Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury.

Grommes J, Alard JE, Drechsler M, Wantha S, Mörgelin M, Kuebler WM, Jacobs M, von Hundelshausen P, Markart P, Wygrecka M, Preissner KT, Hackeng TM, Koenen RR, Weber C, Soehnlein O.

Am J Respir Crit Care Med. 2012 Mar 15;185(6):628-36. doi: 10.1164/rccm.201108-1533OC. Epub 2012 Jan 12.

25.

Platelets in atherosclerosis.

Lievens D, von Hundelshausen P.

Thromb Haemost. 2011 Nov;106(5):827-38. doi: 10.1160/TH11-08-0592. Epub 2011 Oct 20. Review.

PMID:
22012554
26.

CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment.

Sarabi A, Kramp BK, Drechsler M, Hackeng TM, Soehnlein O, Weber C, Koenen RR, Von Hundelshausen P.

J Thromb Haemost. 2011 Jan;9(1):209-19. doi: 10.1111/j.1538-7836.2010.04119.x.

27.

Circulating monocyte subsets and cardiovascular risk factors in coronary artery disease.

Hristov M, Leyendecker T, Schuhmann C, von Hundelshausen P, Heussen N, Kehmeier E, Krötz F, Sohn HY, Klauss V, Weber C.

Thromb Haemost. 2010 Aug;104(2):412-4. doi: 10.1160/TH10-01-0069. Epub 2010 Apr 29. No abstract available.

PMID:
20431842
28.

CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis.

Zaldivar MM, Pauels K, von Hundelshausen P, Berres ML, Schmitz P, Bornemann J, Kowalska MA, Gassler N, Streetz KL, Weiskirchen R, Trautwein C, Weber C, Wasmuth HE.

Hepatology. 2010 Apr;51(4):1345-53. doi: 10.1002/hep.23435.

PMID:
20162727
29.

An optimized flow cytometry protocol for analysis of angiogenic monocytes and endothelial progenitor cells in peripheral blood.

Hristov M, Schmitz S, Schuhmann C, Leyendecker T, von Hundelshausen P, Krötz F, Sohn HY, Nauwelaers FA, Weber C.

Cytometry A. 2009 Oct;75(10):848-53. doi: 10.1002/cyto.a.20772.

30.

The basic residue cluster (55)KKWVR(59) in CCL5 is required for in vivo biologic function.

Segerer S, Johnson Z, Rek A, Baltus T, von Hundelshausen P, Kungl AJ, Proudfoot AE, Weber C, Nelson PJ.

Mol Immunol. 2009 Aug;46(13):2533-8. doi: 10.1016/j.molimm.2009.05.015. Epub 2009 Jun 12.

PMID:
19524301
31.

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice.

Koenen RR, von Hundelshausen P, Nesmelova IV, Zernecke A, Liehn EA, Sarabi A, Kramp BK, Piccinini AM, Paludan SR, Kowalska MA, Kungl AJ, Hackeng TM, Mayo KH, Weber C.

Nat Med. 2009 Jan;15(1):97-103. doi: 10.1038/nm.1898. Epub 2009 Jan 4.

PMID:
19122657
32.

Platelet-mediated enhancement of leukocyte adhesion.

von Hundelshausen P, Koenen RR, Weber C.

Microcirculation. 2009 Jan;16(1):84-96. doi: 10.1080/10739680802564787. Review.

PMID:
19115139
33.

Platelet chemokines in vascular disease.

Gleissner CA, von Hundelshausen P, Ley K.

Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):1920-7. doi: 10.1161/ATVBAHA.108.169417. Epub 2008 Aug 21. Review.

34.

Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.

Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A.

J Immunol. 2007 Jun 15;178(12):8064-72.

35.

Platelet-derived chemokines in vascular biology.

von Hundelshausen P, Petersen F, Brandt E.

Thromb Haemost. 2007 May;97(5):704-13. Review.

PMID:
17479180
36.

Inflammatory blues turns velvet skin into rawhide: monocyte rolling on modified endothelial PSGL-1.

Koenen RR, von Hundelshausen P, Weber C.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):990-2. No abstract available.

PMID:
17442895
37.

Platelets as immune cells: bridging inflammation and cardiovascular disease.

von Hundelshausen P, Weber C.

Circ Res. 2007 Jan 5;100(1):27-40. Review.

PMID:
17204662
38.

Indium-111 oxine labelling affects the cellular integrity of haematopoietic progenitor cells.

Nowak B, Weber C, Schober A, Zeiffer U, Liehn EA, von Hundelshausen P, Reinartz P, Schaefer WM, Buell U.

Eur J Nucl Med Mol Imaging. 2007 May;34(5):715-721. doi: 10.1007/s00259-006-0275-3. Epub 2006 Nov 10.

PMID:
17096094
39.

Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice.

Zernecke A, Liehn EA, Fraemohs L, von Hundelshausen P, Koenen RR, Corada M, Dejana E, Weber C.

Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):e10-3. Epub 2005 Nov 23.

PMID:
16306427
40.

Differential and additive effects of platelet-derived chemokines on monocyte arrest on inflamed endothelium under flow conditions.

Baltus T, von Hundelshausen P, Mause SF, Buhre W, Rossaint R, Weber C.

J Leukoc Biol. 2005 Aug;78(2):435-41. Epub 2005 May 17.

PMID:
15899984
41.

Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium.

Mause SF, von Hundelshausen P, Zernecke A, Koenen RR, Weber C.

Arterioscler Thromb Vasc Biol. 2005 Jul;25(7):1512-8. Epub 2005 May 12.

PMID:
15890969
42.

SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells.

Zernecke A, Schober A, Bot I, von Hundelshausen P, Liehn EA, Möpps B, Mericskay M, Gierschik P, Biessen EA, Weber C.

Circ Res. 2005 Apr 15;96(7):784-91. Epub 2005 Mar 10.

PMID:
15761195
43.

Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets.

Schober A, Zernecke A, Liehn EA, von Hundelshausen P, Knarren S, Kuziel WA, Weber C.

Circ Res. 2004 Nov 26;95(11):1125-33. Epub 2004 Nov 4.

PMID:
15528472
44.

Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium.

von Hundelshausen P, Koenen RR, Sack M, Mause SF, Adriaens W, Proudfoot AE, Hackeng TM, Weber C.

Blood. 2005 Feb 1;105(3):924-30. Epub 2004 Sep 30.

45.

Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury.

Schober A, Manka D, von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ, Ley K, Weber C.

Circulation. 2002 Sep 17;106(12):1523-9.

PMID:
12234959
46.

Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage.

Neuzil J, Schröder A, von Hundelshausen P, Zernecke A, Weber T, Gellert N, Weber C.

Biochemistry. 2001 Apr 17;40(15):4686-92.

PMID:
11294636
47.

RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.

von Hundelshausen P, Weber KS, Huo Y, Proudfoot AE, Nelson PJ, Ley K, Weber C.

Circulation. 2001 Apr 3;103(13):1772-7.

PMID:
11282909
48.

Differential chemokine receptor expression and function in human monocyte subpopulations.

Weber C, Belge KU, von Hundelshausen P, Draude G, Steppich B, Mack M, Frankenberger M, Weber KS, Ziegler-Heitbrock HW.

J Leukoc Biol. 2000 May;67(5):699-704.

PMID:
10811011
49.

Distinct scavenger receptor expression and function in the human CD14(+)/CD16(+) monocyte subset.

Draude G, von Hundelshausen P, Frankenberger M, Ziegler-Heitbrock HW, Weber C.

Am J Physiol. 1999 Apr;276(4):H1144-9. doi: 10.1152/ajpheart.1999.276.4.H1144.

PMID:
10199836
50.

Differential immobilization and hierarchical involvement of chemokines in monocyte arrest and transmigration on inflamed endothelium in shear flow.

Weber KS, von Hundelshausen P, Clark-Lewis I, Weber PC, Weber C.

Eur J Immunol. 1999 Feb;29(2):700-12.

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