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Items: 18

1.

Clinical Development of Aducanumab, an Anti-Aβ Human Monoclonal Antibody Being Investigated for the Treatment of Early Alzheimer's Disease.

Budd Haeberlein S, O'Gorman J, Chiao P, Bussière T, von Rosenstiel P, Tian Y, Zhu Y, von Hehn C, Gheuens S, Skordos L, Chen T, Sandrock A.

J Prev Alzheimers Dis. 2017;4(4):255-263. doi: 10.14283/jpad.2017.39.

PMID:
29181491
2.

Immune response to vaccines is maintained in patients treated with dimethyl fumarate.

von Hehn C, Howard J, Liu S, Meka V, Pultz J, Mehta D, Prada C, Ray S, Edwards MR, Sheikh SI.

Neurol Neuroimmunol Neuroinflamm. 2017 Nov 15;5(1):e409. doi: 10.1212/NXI.0000000000000409. eCollection 2018 Jan.

3.

Gastrointestinal Tolerability of Delayed-Release Dimethyl Fumarate in a Multicenter, Open-Label Study of Patients with Relapsing Forms of Multiple Sclerosis (MANAGE).

Fox EJ, Vasquez A, Grainger W, Ma TS, von Hehn C, Walsh J, Li J, Zambrano J.

Int J MS Care. 2016 Jan-Feb;18(1):9-18. doi: 10.7224/1537-2073.2014-101.

4.

Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.

Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, Agac B, Haworth O, Seki H, Penninger JM, Kuchroo VK, Bean BP, Levy BD, Woolf CJ.

Neuron. 2015 Jul 15;87(2):341-54. doi: 10.1016/j.neuron.2015.06.007. Epub 2015 Jun 25.

5.

Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.

Brenneis C, Kistner K, Puopolo M, Jo S, Roberson D, Sisignano M, Segal D, Cobos EJ, Wainger BJ, Labocha S, Ferreirós N, von Hehn C, Tran J, Geisslinger G, Reeh PW, Bean BP, Woolf CJ.

Br J Pharmacol. 2014 Jan;171(2):438-51. doi: 10.1111/bph.12466.

6.

Bacteria activate sensory neurons that modulate pain and inflammation.

Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ.

Nature. 2013 Sep 5;501(7465):52-7. doi: 10.1038/nature12479. Epub 2013 Aug 21.

7.

Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology.

Chiu IM, von Hehn CA, Woolf CJ.

Nat Neurosci. 2012 Jul 26;15(8):1063-7. doi: 10.1038/nn.3144.

8.

5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals.

Sisignano M, Park CK, Angioni C, Zhang DD, von Hehn C, Cobos EJ, Ghasemlou N, Xu ZZ, Kumaran V, Lu R, Grant A, Fischer MJ, Schmidtko A, Reeh P, Ji RR, Woolf CJ, Geisslinger G, Scholich K, Brenneis C.

J Neurosci. 2012 May 2;32(18):6364-72. doi: 10.1523/JNEUROSCI.5793-11.2012.

9.

Deconstructing the neuropathic pain phenotype to reveal neural mechanisms.

von Hehn CA, Baron R, Woolf CJ.

Neuron. 2012 Feb 23;73(4):638-52. doi: 10.1016/j.neuron.2012.02.008. Review.

10.

Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases.

Bessac BF, Sivula M, von Hehn CA, Caceres AI, Escalera J, Jordt SE.

FASEB J. 2009 Apr;23(4):1102-14. doi: 10.1096/fj.08-117812. Epub 2008 Nov 26.

11.

Amino-termini isoforms of the Slack K+ channel, regulated by alternative promoters, differentially modulate rhythmic firing and adaptation.

Brown MR, Kronengold J, Gazula VR, Spilianakis CG, Flavell RA, von Hehn CA, Bhattacharjee A, Kaczmarek LK.

J Physiol. 2008 Nov 1;586(21):5161-79. doi: 10.1113/jphysiol.2008.160861. Epub 2008 Sep 11.

12.

TRPA1 mediates the noxious effects of natural sesquiterpene deterrents.

Escalera J, von Hehn CA, Bessac BF, Sivula M, Jordt SE.

J Biol Chem. 2008 Aug 29;283(35):24136-44. doi: 10.1074/jbc.M710280200. Epub 2008 Jun 11.

13.

TRPA1 is a major oxidant sensor in murine airway sensory neurons.

Bessac BF, Sivula M, von Hehn CA, Escalera J, Cohn L, Jordt SE.

J Clin Invest. 2008 May;118(5):1899-910. doi: 10.1172/JCI34192.

14.

Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia.

Chen H, von Hehn C, Kaczmarek LK, Ment LR, Pober BR, Hisama FM.

Neurogenetics. 2007 Apr;8(2):131-5. Epub 2006 Nov 29.

15.

Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels.

Kaczmarek LK, Bhattacharjee A, Desai R, Gan L, Song P, von Hehn CA, Whim MD, Yang B.

Hear Res. 2005 Aug;206(1-2):133-45. Review.

PMID:
16081004
16.

Localization of the Na+-activated K+ channel Slick in the rat central nervous system.

Bhattacharjee A, von Hehn CA, Mei X, Kaczmarek LK.

J Comp Neurol. 2005 Mar 28;484(1):80-92.

PMID:
15717307
17.
18.

Modulation of the kv3.1b potassium channel isoform adjusts the fidelity of the firing pattern of auditory neurons.

Macica CM, von Hehn CA, Wang LY, Ho CS, Yokoyama S, Joho RH, Kaczmarek LK.

J Neurosci. 2003 Feb 15;23(4):1133-41.

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