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Items: 1 to 50 of 157

1.

Postnatal morphological lung development of wild type and CD26/DPP4 deficient rat pups in dependency of LPS exposure.

Wagener I, Jungen M, von Hörsten S, Stephan M, Schmiedl A.

Ann Anat. 2019 Oct 22:151423. doi: 10.1016/j.aanat.2019.151423. [Epub ahead of print]

PMID:
31654734
2.

Silhouette-Length-Scaled Gait Parameters for Motor Functional Analysis in Mice and Rats.

Timotius IK, Moceri S, Plank AC, Habermeyer J, Canneva F, Winkler J, Klucken J, Casadei N, Riess O, Eskofier B, von Hörsten S.

eNeuro. 2019 Nov 1;6(6). pii: ENEURO.0100-19.2019. doi: 10.1523/ENEURO.0100-19.2019. Print 2019 Nov/Dec.

3.

Systematic data analysis and data mining in CatWalk gait analysis by heat mapping exemplified in rodent models for neurodegenerative diseases.

Timotius IK, Canneva F, Minakaki G, Moceri S, Plank AC, Casadei N, Riess O, Winkler J, Klucken J, Eskofier B, von Hörsten S.

J Neurosci Methods. 2019 Oct 1;326:108367. doi: 10.1016/j.jneumeth.2019.108367. Epub 2019 Jul 24. Review.

PMID:
31351096
4.

Dipeptidyl-peptidase-4 as a marker of activated fibroblasts and a potential target for the treatment of fibrosis in Systemic Sclerosis.

Soare A, Györfi HA, Matei AE, Dees C, Rauber S, Wohlfahrt T, Chen CW, Ludolph I, Horch RE, Bäuerle T, von Hörsten S, Mihai C, Distler O, Ramming A, Schett G, Distler JHW.

Arthritis Rheumatol. 2019 Jul 26. doi: 10.1002/art.41058. [Epub ahead of print]

PMID:
31350829
5.

Structural changes within the bifunctional cryptochrome/photolyase CraCRY upon blue light excitation.

Franz-Badur S, Penner A, Straß S, von Horsten S, Linne U, Essen LO.

Sci Rep. 2019 Jul 9;9(1):9896. doi: 10.1038/s41598-019-45885-7.

6.

Differential Levels and Phosphorylation of Type 1 Inositol 1,4,5-Trisphosphate Receptor in Four Different Murine Models of Huntington Disease.

Post JI, Leergaard TB, Ratz V, Walaas SI, von Hörsten S, Nissen-Meyer LSH.

J Huntingtons Dis. 2019;8(3):271-289. doi: 10.3233/JHD-180301.

PMID:
31256144
7.

Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer's disease.

Hartlage-Rübsamen M, Ratz V, Zeitschel U, Finzel L, Machner L, Köppen J, Schulze A, Demuth HU, von Hörsten S, Höfling C, Roßner S.

Acta Neuropathol Commun. 2019 May 20;7(1):79. doi: 10.1186/s40478-019-0726-2.

8.

Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats.

Uzuneser TC, Speidel J, Kogias G, Wang AL, de Souza Silva MA, Huston JP, Zoicas I, von Hörsten S, Kornhuber J, Korth C, Müller CP.

Front Psychiatry. 2019 Apr 9;10:222. doi: 10.3389/fpsyt.2019.00222. eCollection 2019.

9.

Differential severity of LPS-induced lung injury in CD26/DPP4 positive and deficient F344 rats.

Zientara A, Stephan M, von Hörsten S, Schmiedl A.

Histol Histopathol. 2019 Oct;34(10):1151-1171. doi: 10.14670/HH-18-117. Epub 2019 Apr 12.

PMID:
30977110
10.

Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy.

Minakaki G, Canneva F, Chevessier F, Bode F, Menges S, Timotius IK, Kalinichenko LS, Meixner H, Müller CP, Eskofier BM, Casadei N, Riess O, Schröder R, Winkler J, Xiang W, von Hörsten S, Klucken J.

Behav Brain Res. 2019 May 2;363:199-215. doi: 10.1016/j.bbr.2018.11.035. Epub 2018 Dec 30.

PMID:
30599154
11.

Arabidopsis phytochrome A nuclear translocation is mediated by a far-red elongated hypocotyl 1-importin complex.

Helizon H, Rösler-Dalton J, Gasch P, von Horsten S, Essen LO, Zeidler M.

Plant J. 2018 Dec;96(6):1255-1268. doi: 10.1111/tpj.14107. Epub 2018 Oct 26.

PMID:
30256472
12.

Schizophrenia dimension-specific antipsychotic drug action and failure in amphetamine-sensitized psychotic-like rats.

Uzuneser TC, Schindehütte M, Dere E, von Hörsten S, Kornhuber J, Grömer TW, Müller CP.

Eur Neuropsychopharmacol. 2018 Dec;28(12):1382-1393. doi: 10.1016/j.euroneuro.2018.09.005. Epub 2018 Sep 20.

PMID:
30243682
13.

Role of hypothalamus-pituitary-adrenal axis modulation in the stress-resilient phenotype of DPP4-deficient rats.

Golub Y, Schildbach EM, Touma C, Kratz O, Moll GH, von Hörsten S, Canneva F.

Behav Brain Res. 2019 Jan 1;356:243-249. doi: 10.1016/j.bbr.2018.08.029. Epub 2018 Aug 31.

PMID:
30176267
14.

Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition.

Siebzehnrübl FA, Raber KA, Urbach YK, Schulze-Krebs A, Canneva F, Moceri S, Habermeyer J, Achoui D, Gupta B, Steindler DA, Stephan M, Nguyen HP, Bonin M, Riess O, Bauer A, Aigner L, Couillard-Despres S, Paucar MA, Svenningsson P, Osmand A, Andreew A, Zabel C, Weiss A, Kuhn R, Moussaoui S, Blockx I, Van der Linden A, Cheong RY, Roybon L, Petersén Å, von Hörsten S.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8765-E8774. doi: 10.1073/pnas.1807962115. Epub 2018 Aug 27.

15.

A dopaminergic mechanism of antipsychotic drug efficacy, failure, and failure reversal: the role of the dopamine transporter.

Amato D, Canneva F, Cumming P, Maschauer S, Groos D, Dahlmanns JK, Grömer TW, Chiofalo L, Dahlmanns M, Zheng F, Kornhuber J, Prante O, Alzheimer C, von Hörsten S, Müller CP.

Mol Psychiatry. 2018 Jul 23. doi: 10.1038/s41380-018-0114-5. [Epub ahead of print]

PMID:
30038229
16.

Dynamic footprints of α-synucleinopathic mice recorded by CatWalk gait analysis.

Timotius IK, Canneva F, Minakaki G, Pasluosta C, Moceri S, Casadei N, Riess O, Winkler J, Klucken J, von Hörsten S, Eskofier B.

Data Brief. 2018 Jan 3;17:189-193. doi: 10.1016/j.dib.2017.12.067. eCollection 2018 Apr.

17.

Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease.

Plank AC, Canneva F, Raber KA, Urbach YK, Dobner J, Puchades M, Bjaalie JG, Gillmann C, Bäuerle T, Riess O, Nguyen HHP, von Hörsten S.

Front Neurosci. 2018 Jan 25;12:11. doi: 10.3389/fnins.2018.00011. eCollection 2018.

18.

Dynamic footprint based locomotion sway assessment in α-synucleinopathic mice using Fast Fourier Transform and Low Pass Filter.

Timotius IK, Canneva F, Minakaki G, Pasluosta C, Moceri S, Casadei N, Riess O, Winkler J, Klucken J, von Hörsten S, Eskofier B.

J Neurosci Methods. 2018 Feb 15;296:1-11. doi: 10.1016/j.jneumeth.2017.12.004. Epub 2017 Dec 16.

PMID:
29253577
19.

Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.

Thangaratnarajah C, Dinger K, Vohlen C, Klaudt C, Nawabi J, Lopez Garcia E, Kwapiszewska G, Dobner J, Nüsken KD, van Koningsbruggen-Rietschel S, von Hörsten S, Dötsch J, Alejandre Alcázar MA.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L491-L506. doi: 10.1152/ajplung.00432.2016. Epub 2017 Jun 1.

20.

Structural communication between the chromophore-binding pocket and the N-terminal extension in plant phytochrome phyB.

Velázquez Escobar F, Buhrke D, Fernandez Lopez M, Shenkutie SM, von Horsten S, Essen LO, Hughes J, Hildebrandt P.

FEBS Lett. 2017 May;591(9):1258-1265. doi: 10.1002/1873-3468.12642. Epub 2017 Apr 16.

21.

Capturing schizophrenia-like prodromal symptoms in a spinocerebellar ataxia-17 transgenic rat.

Amato D, Canneva F, Nguyen HP, Bauer P, Riess O, von Hörsten S, Müller CP.

J Psychopharmacol. 2017 Apr;31(4):461-473. doi: 10.1177/0269881116675510. Epub 2016 Nov 10.

PMID:
27856682
22.

Impaired Decision Making and Loss of Inhibitory-Control in a Rat Model of Huntington Disease.

El Massioui N, Lamirault C, Yagüe S, Adjeroud N, Garces D, Maillard A, Tallot L, Yu-Taeger L, Riess O, Allain P, Nguyen HP, von Hörsten S, Doyère V.

Front Behav Neurosci. 2016 Oct 26;10:204. eCollection 2016.

23.

Mapping light-driven conformational changes within the photosensory module of plant phytochrome B.

von Horsten S, Straß S, Hellwig N, Gruth V, Klasen R, Mielcarek A, Linne U, Morgner N, Essen LO.

Sci Rep. 2016 Oct 3;6:34366. doi: 10.1038/srep34366.

24.

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.

Höfling C, Morawski M, Zeitschel U, Zanier ER, Moschke K, Serdaroglu A, Canneva F, von Hörsten S, De Simoni MG, Forloni G, Jäger C, Kremmer E, Roßner S, Lichtenthaler SF, Kuhn PH.

Aging Cell. 2016 Oct;15(5):953-63. doi: 10.1111/acel.12508. Epub 2016 Jul 29.

25.

Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1-30 fragment.

Wagner L, Björkqvist M, Lundh SH, Wolf R, Börgel A, Schlenzig D, Ludwig HH, Rahfeld JU, Leavitt B, Demuth HU, Petersén Å, von Hörsten S.

J Neurochem. 2016 Jun;137(5):820-37. doi: 10.1111/jnc.13624.

26.

Identifying neuropeptide Y (NPY) as the main stress-related substrate of dipeptidyl peptidase 4 (DPP4) in blood circulation.

Wagner L, Kaestner F, Wolf R, Stiller H, Heiser U, Manhart S, Hoffmann T, Rahfeld JU, Demuth HU, Rothermundt M, von Hörsten S.

Neuropeptides. 2016 Jun;57:21-34. doi: 10.1016/j.npep.2016.02.007. Epub 2016 Feb 27.

PMID:
26988064
27.

Cut to the chase: a review of CD26/dipeptidyl peptidase-4's (DPP4) entanglement in the immune system.

Klemann C, Wagner L, Stephan M, von Hörsten S.

Clin Exp Immunol. 2016 Jul;185(1):1-21. doi: 10.1111/cei.12781. Epub 2016 May 13. Review.

28.

Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma.

Golub Y, Canneva F, Funke R, Frey S, Distler J, von Hörsten S, Freitag CM, Kratz O, Moll GH, Solati J.

Dev Neurobiol. 2016 Nov;76(11):1254-1265. doi: 10.1002/dneu.22387. Epub 2016 Mar 9.

29.

Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homologue (DASH) proteins.

Wagner L, Klemann C, Stephan M, von Hörsten S.

Clin Exp Immunol. 2016 Jun;184(3):265-83. doi: 10.1111/cei.12757. Epub 2016 Mar 2. Review.

30.

In situ enzymatic activity of transglutaminase isoforms on brain tissue sections of rodents: A new approach to monitor differences in post-translational protein modifications during neurodegeneration.

Schulze-Krebs A, Canneva F, Schnepf R, Dobner J, Dieterich W, von Hörsten S.

Brain Res. 2016 Jan 15;1631:22-33. doi: 10.1016/j.brainres.2015.11.027. Epub 2015 Nov 23.

PMID:
26616340
31.

Myofibrillar instability exacerbated by acute exercise in filaminopathy.

Chevessier F, Schuld J, Orfanos Z, Plank AC, Wolf L, Maerkens A, Unger A, Schlötzer-Schrehardt U, Kley RA, Von Hörsten S, Marcus K, Linke WA, Vorgerd M, van der Ven PF, Fürst DO, Schröder R.

Hum Mol Genet. 2015 Dec 20;24(25):7207-20. doi: 10.1093/hmg/ddv421. Epub 2015 Oct 15.

PMID:
26472074
32.

Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and Periphery.

Wagner L, Wolf R, Zeitschel U, Rossner S, Petersén Å, Leavitt BR, Kästner F, Rothermundt M, Gärtner UT, Gündel D, Schlenzig D, Frerker N, Schade J, Manhart S, Rahfeld JU, Demuth HU, von Hörsten S.

J Neurochem. 2015 Dec;135(5):1019-37. doi: 10.1111/jnc.13378. Epub 2015 Nov 16.

33.

IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes.

Becker A, Eichentopf R, Sedlmeier R, Waniek A, Cynis H, Koch B, Stephan A, Bäuscher C, Kohlmann S, Hoffmann T, Kehlen A, Berg S, Freyse EJ, Osmand A, Plank AC, Roßner S, von Hörsten S, Graubner S, Demuth HU, Schilling S.

Biol Chem. 2016 Jan;397(1):45-55. doi: 10.1515/hsz-2015-0192.

PMID:
26351917
34.

FDG μPET Fails to Detect a Disease-Specific Phenotype in Rats Transgenic for Huntington's Disease – A 15 Months Follow-up Study.

Reilmann R, Lippross V, Hölzner E, Gigengack F, Bohlen S, Kugel H, Deppe M, Osada N, Lücke M, Riess O, Nguyen HP, Von Hörsten S, Schäfers K, Schäfers M, Jacobs AH, Hermann S.

J Huntingtons Dis. 2015;4(1):37-47.

PMID:
26333256
35.

Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington's disease is accompanied by striatal invasion of neuroblasts.

Kandasamy M, Rosskopf M, Wagner K, Klein B, Couillard-Despres S, Reitsamer HA, Stephan M, Nguyen HP, Riess O, Bogdahn U, Winkler J, von Hörsten S, Aigner L.

PLoS One. 2015 Feb 26;10(2):e0116069. doi: 10.1371/journal.pone.0116069. eCollection 2015.

36.

DPP4-deficient congenic rats display blunted stress, improved fear extinction and increased central NPY.

Canneva F, Golub Y, Distler J, Dobner J, Meyer S, von Hörsten S.

Psychoneuroendocrinology. 2015 Mar;53:195-206. doi: 10.1016/j.psyneuen.2015.01.007. Epub 2015 Jan 19.

PMID:
25635612
37.

Differential OVA-induced pulmonary inflammation and unspecific reaction in Dark Agouti (DA) rats contingent on CD26/DPPIV deficiency.

Tasic T, Stephan M, von Hörsten S, Pabst R, Schmiedl A.

Immunobiology. 2014 Nov;219(11):888-900. doi: 10.1016/j.imbio.2014.07.007. Epub 2014 Jul 22.

PMID:
25108564
38.

Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro.

Dimitrijević M, Aleksić I, Vujić V, Stanojević S, Pilipović I, von Hörsten S, Leposavić G.

Age (Dordr). 2014;36(4):9696. doi: 10.1007/s11357-014-9696-2. Epub 2014 Aug 1.

39.

DPP4 inhibitors increase differentially the expression of surfactant proteins in Fischer 344 rats.

Schmiedl A, Grützner D, Hoffmann T, von Hörsten S, Stephan M.

Acta Physiol (Oxf). 2014 Nov;212(3):248-61. doi: 10.1111/apha.12350. Epub 2014 Sep 15.

PMID:
25069535
40.

Automated phenotyping and advanced data mining exemplified in rats transgenic for Huntington's disease.

Urbach YK, Raber KA, Canneva F, Plank AC, Andreasson T, Ponten H, Kullingsjö J, Nguyen HP, Riess O, von Hörsten S.

J Neurosci Methods. 2014 Aug 30;234:38-53. doi: 10.1016/j.jneumeth.2014.06.017. Epub 2014 Jul 11.

PMID:
25020253
41.

Soluble DPP4 originates in part from bone marrow cells and not from the kidney.

Wang Z, Grigo C, Steinbeck J, von Hörsten S, Amann K, Daniel C.

Peptides. 2014 Jul;57:109-17. doi: 10.1016/j.peptides.2014.05.006. Epub 2014 May 27.

PMID:
24874705
42.

Maternal deprivation decelerates postnatal morphological lung development of F344 rats.

Hupa KL, Schmiedl A, Pabst R, Von Hörsten S, Stephan M.

Anat Rec (Hoboken). 2014 Feb;297(2):317-26. doi: 10.1002/ar.22848. Epub 2013 Dec 19.

43.

Effects of dipeptidyl peptidase-4 inhibition in an animal model of experimental asthma: a matter of dose, route, and time.

Stephan M, Suhling H, Schade J, Wittlake M, Tasic T, Klemann C, Pabst R, Jurawitz MC, Raber KA, Hoymann HG, Braun A, Glaab T, Hoffmann T, Schmiedl A, von Hörsten S.

Physiol Rep. 2013 Oct;1(5):e00095. doi: 10.1002/phy2.95. Epub 2013 Oct 2.

44.

Modified impact of emotion on temporal discrimination in a transgenic rat model of Huntington disease.

Faure A, Es-Seddiqi M, Brown BL, Nguyen HP, Riess O, von Hörsten S, Le Blanc P, Desvignes N, Bozon B, El Massioui N, Doyère V.

Front Behav Neurosci. 2013 Sep 26;7:130. doi: 10.3389/fnbeh.2013.00130. eCollection 2013.

45.

Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration.

Becker A, Kohlmann S, Alexandru A, Jagla W, Canneva F, Bäuscher C, Cynis H, Sedlmeier R, Graubner S, Schilling S, Demuth HU, von Hörsten S.

BMC Neurosci. 2013 Oct 1;14:108. doi: 10.1186/1471-2202-14-108.

46.

Transgenic Rat Models of Huntington's Disease.

Carreira JC, Jahanshahi A, Zeef D, Kocabicak E, Vlamings R, von Hörsten S, Temel Y.

Curr Top Behav Neurosci. 2015;22:135-47. doi: 10.1007/7854_2013_245. Review.

PMID:
24013873
47.

From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction.

Hassan Z, Muzaimi M, Navaratnam V, Yusoff NH, Suhaimi FW, Vadivelu R, Vicknasingam BK, Amato D, von Hörsten S, Ismail NI, Jayabalan N, Hazim AI, Mansor SM, Müller CP.

Neurosci Biobehav Rev. 2013 Feb;37(2):138-51. doi: 10.1016/j.neubiorev.2012.11.012. Epub 2012 Dec 1. Review.

PMID:
23206666
48.

Early deficits in declarative and procedural memory dependent behavioral function in a transgenic rat model of Huntington's disease.

Kirch RD, Meyer PT, Geisler S, Braun F, Gehrig S, Langen KJ, von Hörsten S, Nikkhah G, Cassel JC, Döbrössy MD.

Behav Brain Res. 2013 Feb 15;239:15-26. doi: 10.1016/j.bbr.2012.10.048. Epub 2012 Nov 5.

PMID:
23137697
49.

Altered hypothalamic protein expression in a rat model of Huntington's disease.

Cong WN, Cai H, Wang R, Daimon CM, Maudsley S, Raber K, Canneva F, von Hörsten S, Martin B.

PLoS One. 2012;7(10):e47240. doi: 10.1371/journal.pone.0047240. Epub 2012 Oct 18. Erratum in: PLoS One. 2012;7(11). doi:10.1371/annotation/677c26e3-ce52-4837-853a-63c4ed7d72c0.

50.

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats.

Vlamings R, Benazzouz A, Chetrit J, Janssen ML, Kozan R, Visser-Vandewalle V, Steinbusch HW, von Hörsten S, Temel Y.

Neurobiol Dis. 2012 Dec;48(3):488-94. doi: 10.1016/j.nbd.2012.07.006. Epub 2012 Jul 17.

PMID:
22813864

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