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Pneumococcal vaccination rates in immunocompromised patients-A cohort study based on claims data from more than 200,000 patients in Germany.

Schmedt N, Schiffner-Rohe J, Sprenger R, Walker J, von Eiff C, Häckl D.

PLoS One. 2019 Aug 8;14(8):e0220848. doi: 10.1371/journal.pone.0220848. eCollection 2019.


In Vitro Activity of the Bacteriophage Endolysin HY-133 against Staphylococcus aureus Small-Colony Variants and Their Corresponding Wild Types.

Schleimer N, Kaspar U, Knaack D, von Eiff C, Molinaro S, Grallert H, Idelevich EA, Becker K.

Int J Mol Sci. 2019 Feb 7;20(3). pii: E716. doi: 10.3390/ijms20030716.


The Energy-Coupling Factor Transporter Module EcfAA'T, a Novel Candidate for the Genetic Basis of Fatty Acid-Auxotrophic Small-Colony Variants of Staphylococcus aureus.

Schleimer N, Kaspar U, Drescher M, Seggewiß J, von Eiff C, Proctor RA, Peters G, Kriegeskorte A, Becker K.

Front Microbiol. 2018 Aug 14;9:1863. doi: 10.3389/fmicb.2018.01863. eCollection 2018.


In Vitro Susceptibility of Clinical Staphylococcus aureus Small-Colony Variants to β-Lactam and Non-β-Lactam Antibiotics.

Idelevich EA, Kriegeskorte A, Schleimer N, Peters G, von Eiff C, Becker K.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02532-17. doi: 10.1128/AAC.02532-17. Print 2018 Apr.


Serum S100B Protein is Specifically Related to White Matter Changes in Schizophrenia.

Milleit B, Smesny S, Rothermundt M, Preul C, Schroeter ML, von Eiff C, Ponath G, Milleit C, Sauer H, Gaser C.

Front Cell Neurosci. 2016 Mar 8;10:33. doi: 10.3389/fncel.2016.00033. eCollection 2016.


Efficacy of PPV23 in Preventing Pneumococcal Pneumonia in Adults at Increased Risk--A Systematic Review and Meta-Analysis.

Schiffner-Rohe J, Witt A, Hemmerling J, von Eiff C, Leverkus FW.

PLoS One. 2016 Jan 13;11(1):e0146338. doi: 10.1371/journal.pone.0146338. eCollection 2016. Review.


Tigecycline in the Treatment of Patients with Necrotizing Skin and Soft Tissue Infections Due to Multiresistant Bacteria.

Eckmann C, Heizmann W, Bodmann KF, von Eiff C, Petrik C, Loeschmann PA.

Surg Infect (Larchmt). 2015 Oct;16(5):618-25. doi: 10.1089/sur.2014.089. Epub 2015 Jun 26.


Evolution of Staphylococcus aureus under vancomycin selective pressure: the role of the small-colony variant phenotype.

Lenhard JR, von Eiff C, Hong IS, Holden PN, Bear MD, Suen A, Bulman ZP, Tsuji BT.

Antimicrob Agents Chemother. 2015 Feb;59(2):1347-51. doi: 10.1128/AAC.04508-14. Epub 2014 Dec 1.


Staphylococcus aureus small colony variants show common metabolic features in central metabolism irrespective of the underlying auxotrophism.

Kriegeskorte A, Grubmüller S, Huber C, Kahl BC, von Eiff C, Proctor RA, Peters G, Eisenreich W, Becker K.

Front Cell Infect Microbiol. 2014 Oct 21;4:141. doi: 10.3389/fcimb.2014.00141. eCollection 2014.


Clinical efficacy of tigecycline used as monotherapy or in combination regimens for complicated infections with documented involvement of multiresistant bacteria.

Heizmann WR, Löschmann PA, Eckmann C, von Eiff C, Bodmann KF, Petrik C.

Infection. 2015 Feb;43(1):37-43. doi: 10.1007/s15010-014-0691-4. Epub 2014 Nov 4.


Decreased susceptibility of Staphylococcus aureus small-colony variants toward human antimicrobial peptides.

Gläser R, Becker K, von Eiff C, Meyer-Hoffert U, Harder J.

J Invest Dermatol. 2014 Sep;134(9):2347-2350. doi: 10.1038/jid.2014.176. Epub 2014 Apr 9.


Small changes in environmental parameters lead to alterations in antibiotic resistance, cell morphology and membrane fatty acid composition in Staphylococcus lugdunensis.

Crompton MJ, Dunstan RH, Macdonald MM, Gottfries J, von Eiff C, Roberts TK.

PLoS One. 2014 Apr 8;9(4):e92296. doi: 10.1371/journal.pone.0092296. eCollection 2014.


[Persistent and recurrent skin and soft tissue infections by Staphylococcus aureus. Impact of the small colony-variant (SCV) phenotype and of Panton-Valentine leukocidin (PVL)-positive S. aureus isolates].

Becker K, Kriegeskorte A, Sunderkötter C, Löffler B, von Eiff C.

Hautarzt. 2014 Jan;65(1):15-25. doi: 10.1007/s00105-013-2636-8. German.


Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011).

Schaumburg F, Idelevich EA, Peters G, Mellmann A, von Eiff C, Becker K; Study Group.

Clin Microbiol Infect. 2014 Sep;20(9):O554-7. doi: 10.1111/1469-0691.12519. Epub 2014 Jan 23.


Staphylococcal disease in Africa: another neglected 'tropical' disease.

Herrmann M, Abdullah S, Alabi A, Alonso P, Friedrich AW, Fuhr G, Germann A, Kern WV, Kremsner PG, Mandomando I, Mellmann AC, Pluschke G, Rieg S, Ruffing U, Schaumburg F, Tanner M, Peters G, von Briesen H, von Eiff C, von Müller L, Grobusch MP.

Future Microbiol. 2013 Jan;8(1):17-26. doi: 10.2217/fmb.12.126. Review.


Streptococcus pneumoniae colonization in remote African Pygmies.

Schaumburg F, Alabi A, von Eiff C, Flamen A, Traore H, Grobusch MP, Peters G, Kremsner PG, van der Linden M.

Trans R Soc Trop Med Hyg. 2013 Feb;107(2):105-9. doi: 10.1093/trstmh/trs018. Epub 2012 Nov 14.


Therapy of 1,025 severely ill patients with complicated infections in a German multicenter study: safety profile and efficacy of tigecycline in different treatment modalities.

Bodmann KF, Heizmann WR, von Eiff C, Petrik C, Löschmann PA, Eckmann C.

Chemotherapy. 2012;58(4):282-94. doi: 10.1159/000342451. Epub 2012 Oct 4.


Susceptibility of Staphylococcus aureus bacteremia strains to different skin-derived antimicrobial proteins.

Köten B, Becker K, Podschun R, von Eiff C, Meyer-Hoffert U, Harder J, Gläser R.

Arch Dermatol Res. 2012 Oct;304(8):633-7. doi: 10.1007/s00403-012-1284-7. Epub 2012 Sep 6.


Nasal carriage as a source of agr-defective Staphylococcus aureus bacteremia.

Smyth DS, Kafer JM, Wasserman GA, Velickovic L, Mathema B, Holzman RS, Knipe TA, Becker K, von Eiff C, Peters G, Chen L, Kreiswirth BN, Novick RP, Shopsin B.

J Infect Dis. 2012 Oct;206(8):1168-77. Epub 2012 Aug 2.


Population dynamics among methicillin-resistant Staphylococcus aureus isolates in Germany during a 6-year period.

Schaumburg F, Köck R, Mellmann A, Richter L, Hasenberg F, Kriegeskorte A, Friedrich AW, Gatermann S, Peters G, von Eiff C, Becker K; study group.

J Clin Microbiol. 2012 Oct;50(10):3186-92. doi: 10.1128/JCM.01174-12. Epub 2012 Jul 18.


Catheter colonization and abscess formation due to Staphylococcus epidermidis with normal and small-colony-variant phenotype is mouse strain dependent.

Sander G, Börner T, Kriegeskorte A, von Eiff C, Becker K, Mahabir E.

PLoS One. 2012;7(5):e36602. doi: 10.1371/journal.pone.0036602. Epub 2012 May 7.


Effect of low temperature on growth and ultra-structure of Staphylococcus spp.

Onyango LA, Dunstan RH, Gottfries J, von Eiff C, Roberts TK.

PLoS One. 2012;7(1):e29031. doi: 10.1371/journal.pone.0029031. Epub 2012 Jan 24.


Auxotrophic mutant of Staphylococcus aureus interferes with nasal colonization by the wild type.

Barbagelata MS, Alvarez L, Gordiola M, Tuchscherr L, von Eiff C, Becker K, Sordelli D, Buzzola F.

Microbes Infect. 2011 Nov;13(12-13):1081-90. doi: 10.1016/j.micinf.2011.06.010. Epub 2011 Jul 13.


Prospective, non-interventional, multi-centre trial of tigecycline in the treatment of severely ill patients with complicated infections: new insights into clinical results and treatment practice.

Eckmann C, Heizmann WR, Leitner E, von Eiff C, Bodmann KF.

Chemotherapy. 2011;57(4):275-84. doi: 10.1159/000329406. Epub 2011 Jul 21.


In vitro activity against Staphylococcus aureus of a novel antimicrobial agent, PRF-119, a recombinant chimeric bacteriophage endolysin.

Idelevich EA, von Eiff C, Friedrich AW, Iannelli D, Xia G, Peters G, Peschel A, Wanninger I, Becker K.

Antimicrob Agents Chemother. 2011 Sep;55(9):4416-9. doi: 10.1128/AAC.00217-11. Epub 2011 Jul 11.


Functional assessment of a promoter polymorphism in S100B, a putative risk variant for bipolar disorder.

Dagdan E, Morris DW, Campbell M, Hill M, Rothermundt M, Kästner F, Hohoff C, von Eiff C, Krakowitzky P, Gill M, McKeon P, Roche S.

Am J Med Genet B Neuropsychiatr Genet. 2011 Sep;156B(6):691-9. doi: 10.1002/ajmg.b.31211. Epub 2011 Jun 28.


Small colony variants of Staphylococcus aureus reveal distinct protein profiles.

Kriegeskorte A, König S, Sander G, Pirkl A, Mahabir E, Proctor RA, von Eiff C, Peters G, Becker K.

Proteomics. 2011 Jun;11(12):2476-90. doi: 10.1002/pmic.201000796. Epub 2011 May 18.


Genomic and proteomic characterization of Staphylococcus aureus mastitis isolates of bovine origin.

Wolf C, Kusch H, Monecke S, Albrecht D, Holtfreter S, von Eiff C, Petzl W, Rainard P, Bröker BM, Engelmann S.

Proteomics. 2011 Jun;11(12):2491-502. doi: 10.1002/pmic.201000698. Epub 2011 May 18.


Population structure of Staphylococcus aureus from remote African Babongo Pygmies.

Schaumburg F, Köck R, Friedrich AW, Soulanoudjingar S, Ngoa UA, von Eiff C, Issifou S, Kremsner PG, Herrmann M, Peters G, Becker K.

PLoS Negl Trop Dis. 2011 May 10;5(5):e1150. doi: 10.1371/journal.pntd.0001150.


Resistance trends and in vitro activity of tigecycline and 17 other antimicrobial agents against Gram-positive and Gram-negative organisms, including multidrug-resistant pathogens, in Germany.

Kresken M, Becker K, Seifert H, Leitner E, Körber-Irrgang B, von Eiff C, Löschmann PA; Study Group.

Eur J Clin Microbiol Infect Dis. 2011 Sep;30(9):1095-103. doi: 10.1007/s10096-011-1197-y. Epub 2011 Feb 24.


Intra- and extracellular activities of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with a small-colony-variant phenotype in an in vitro model of THP-1 macrophages and an in vivo mouse peritonitis model.

Sandberg A, Lemaire S, Van Bambeke F, Tulkens PM, Hughes D, von Eiff C, Frimodt-Møller N.

Antimicrob Agents Chemother. 2011 Apr;55(4):1443-52. doi: 10.1128/AAC.00205-10. Epub 2011 Jan 31.


Staphylococcus aureus small-colony variants are adapted phenotypes for intracellular persistence.

Tuchscherr L, Heitmann V, Hussain M, Viemann D, Roth J, von Eiff C, Peters G, Becker K, Löffler B.

J Infect Dis. 2010 Oct 1;202(7):1031-40. doi: 10.1086/656047.


The matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS)-based protein peaks of 4448 and 5302 Da are not associated with the presence of Panton-Valentine leukocidin.

Szabados F, Becker K, von Eiff C, Kaase M, Gatermann S.

Int J Med Microbiol. 2011 Jan;301(1):58-63. doi: 10.1016/j.ijmm.2010.05.005. Epub 2010 Aug 11.


Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.

Werth N, Beerlage C, Rosenberger C, Yazdi AS, Edelmann M, Amr A, Bernhardt W, von Eiff C, Becker K, Schäfer A, Peschel A, Kempf VA.

PLoS One. 2010 Jul 14;5(7):e11576. doi: 10.1371/journal.pone.0011576.


Staphylococcus aureus invades the epithelium in nasal polyposis and induces IL-6 in nasal epithelial cells in vitro.

Sachse F, Becker K, von Eiff C, Metze D, Rudack C.

Allergy. 2010 Nov;65(11):1430-7. doi: 10.1111/j.1398-9995.2010.02381.x.


Candida albicans and its metabolite gliotoxin inhibit platelet function via interaction with thiols.

Bertling A, Niemann S, Uekötter A, Fegeler W, Lass-Flörl C, von Eiff C, Kehrel BE.

Thromb Haemost. 2010 Aug;104(2):270-8. doi: 10.1160/TH09-11-0769. Epub 2010 Apr 29.


Redox sensing by a Rex-family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus.

Pagels M, Fuchs S, Pané-Farré J, Kohler C, Menschner L, Hecker M, McNamarra PJ, Bauer MC, von Wachenfeldt C, Liebeke M, Lalk M, Sander G, von Eiff C, Proctor RA, Engelmann S.

Mol Microbiol. 2010 Jun 1;76(5):1142-61. doi: 10.1111/j.1365-2958.2010.07105.x. Epub 2010 Mar 30.


A poke into the diversity and associations within human anterior nare microbial communities.

Wos-Oxley ML, Plumeier I, von Eiff C, Taudien S, Platzer M, Vilchez-Vargas R, Becker K, Pieper DH.

ISME J. 2010 Jul;4(7):839-51. doi: 10.1038/ismej.2010.15. Epub 2010 Feb 25.


Identification of differentially expressed small non-protein-coding RNAs in Staphylococcus aureus displaying both the normal and the small-colony variant phenotype.

Abu-Qatouseh LF, Chinni SV, Seggewiss J, Proctor RA, Brosius J, Rozhdestvensky TS, Peters G, von Eiff C, Becker K.

J Mol Med (Berl). 2010 Jun;88(6):565-75. doi: 10.1007/s00109-010-0597-2. Epub 2010 Feb 12.


Reduction of periprosthetic infection with silver-coated megaprostheses in patients with bone sarcoma.

Hardes J, von Eiff C, Streitbuerger A, Balke M, Budny T, Henrichs MP, Hauschild G, Ahrens H.

J Surg Oncol. 2010 Apr 1;101(5):389-95. doi: 10.1002/jso.21498.


Immunomodulation of nasal epithelial cells by Staphylococcus aureus-derived serine proteases.

Rudack C, Sachse F, Albert N, Becker K, von Eiff C.

J Immunol. 2009 Dec 1;183(11):7592-601. doi: 10.4049/jimmunol.0803902. Epub 2009 Nov 16.


ATIII attenuates endotoxemia induced healing impairment in the colon.

Diller R, Stratmann U, Minin E, von Eiff C, Bäumer G, Huismans H, Helmschmied T, Becker K, Spiegel HU.

J Surg Res. 2009 Nov;157(1):4-13. doi: 10.1016/j.jss.2008.10.008. Epub 2008 Nov 6.


Vancomycin and daptomycin pharmacodynamics differ against a site-directed Staphylococcus epidermidis mutant displaying the small-colony-variant phenotype.

Wu M, von Eiff C, Al Laham N, Tsuji BT.

Antimicrob Agents Chemother. 2009 Sep;53(9):3992-5. doi: 10.1128/AAC.01597-08. Epub 2009 Jun 29.


Energy-dependent stimulatory and inhibitory effects of extracorporeal shock waves on bacteria and on gentamicin activity.

Horn C, Gerdesmeyer L, von Eiff C, Gradinger R, Gollwitzer H.

Med Sci Monit. 2009 Jun;15(6):MT77-83.


Risk variants in the S100B gene predict elevated S100B serum concentrations in healthy individuals.

Hohoff C, Ponath G, Freitag CM, Kästner F, Krakowitzky P, Domschke K, Koelkebeck K, Kipp F, von Eiff C, Deckert J, Rothermundt M.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):291-7. doi: 10.1002/ajmg.b.30950.


Incidence and risk factors for community-acquired acute gastroenteritis in north-west Germany in 2004.

Karsten C, Baumgarte S, Friedrich AW, von Eiff C, Becker K, Wosniok W, Ammon A, Bockemühl J, Karch H, Huppertz HI.

Eur J Clin Microbiol Infect Dis. 2009 Aug;28(8):935-43. doi: 10.1007/s10096-009-0729-1. Epub 2009 Mar 25.


Daptomycin pharmacodynamics against Staphylococcus aureus hemB mutants displaying the small colony variant phenotype.

Begic D, von Eiff C, Tsuji BT.

J Antimicrob Chemother. 2009 May;63(5):977-81. doi: 10.1093/jac/dkp069. Epub 2009 Mar 19.


Capsule expression and genotypic differences among Staphylococcus aureus isolates from patients with chronic or acute osteomyelitis.

Lattar SM, Tuchscherr LP, Caccuri RL, Centrón D, Becker K, Alonso CA, Barberis C, Miranda G, Buzzola FR, von Eiff C, Sordelli DO.

Infect Immun. 2009 May;77(5):1968-75. doi: 10.1128/IAI.01214-08. Epub 2009 Mar 9.


Cross-border comparison of the admission prevalence and clonal structure of meticillin-resistant Staphylococcus aureus.

Köck R, Brakensiek L, Mellmann A, Kipp F, Henderikx M, Harmsen D, Daniels-Haardt I, von Eiff C, Becker K, Hendrix MG, Friedrich AW.

J Hosp Infect. 2009 Apr;71(4):320-6. doi: 10.1016/j.jhin.2008.12.001. Epub 2009 Feb 6.


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