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Items: 14

1.

Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1.

Hayashi A, Giakoumakis NN, Heidebrecht T, Ishii T, Panagopoulos A, Caillat C, Takahara M, Hibbert RG, Suenaga N, Stadnik-Spiewak M, Takahashi T, Shiomi Y, Taraviras S, von Castelmur E, Lygerou Z, Perrakis A, Nishitani H.

Life Sci Alliance. 2018 Dec 31;1(6):e201800238. doi: 10.26508/lsa.201800238. eCollection 2018 Dec.

2.

PLA2G16 represents a switch between entry and clearance of Picornaviridae.

Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR.

Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11.

PMID:
28077878
3.

Structural advances on titin: towards an atomic understanding of multi-domain functions in myofilament mechanics and scaffolding.

Zacharchenko T, von Castelmur E, Rigden DJ, Mayans O.

Biochem Soc Trans. 2015 Oct;43(5):850-5. doi: 10.1042/BST20150084. Review.

PMID:
26517893
4.

CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling.

Hiruma Y, Sacristan C, Pachis ST, Adamopoulos A, Kuijt T, Ubbink M, von Castelmur E, Perrakis A, Kops GJ.

Science. 2015 Jun 12;348(6240):1264-7. doi: 10.1126/science.aaa4055. Epub 2015 Jun 11.

5.

Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1.

Franke B, Gasch A, Rodriguez D, Chami M, Khan MM, Rudolf R, Bibby J, Hanashima A, Bogomolovas J, von Castelmur E, Rigden DJ, Uson I, Labeit S, Mayans O.

Open Biol. 2014 Mar 26;4:130172. doi: 10.1098/rsob.130172.

6.

A TPR domain-containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B.

Nijenhuis W, von Castelmur E, Littler D, De Marco V, Tromer E, Vleugel M, van Osch MH, Snel B, Perrakis A, Kops GJ.

J Cell Biol. 2013 Apr 15;201(2):217-31. doi: 10.1083/jcb.201210033. Epub 2013 Apr 8.

7.

Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.

von Castelmur E, Strümpfer J, Franke B, Bogomolovas J, Barbieri S, Qadota H, Konarev PV, Svergun DI, Labeit S, Benian GM, Schulten K, Mayans O.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13608-13. doi: 10.1073/pnas.1200697109. Epub 2012 Aug 6.

8.

Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

Heidebrecht T, Fish A, von Castelmur E, Johnson KA, Zaccai G, Borst P, Perrakis A.

J Am Chem Soc. 2012 Aug 15;134(32):13357-65. doi: 10.1021/ja303423t. Epub 2012 Jul 31.

PMID:
22775585
9.

The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.

Suijkerbuijk SJ, van Dam TJ, Karagöz GE, von Castelmur E, Hubner NC, Duarte AM, Vleugel M, Perrakis A, Rüdiger SG, Snel B, Kops GJ.

Dev Cell. 2012 Jun 12;22(6):1321-9. doi: 10.1016/j.devcel.2012.03.009.

10.

Tertiary and secondary structure elasticity of a six-Ig titin chain.

Lee EH, Hsin J, von Castelmur E, Mayans O, Schulten K.

Biophys J. 2010 Mar 17;98(6):1085-95. doi: 10.1016/j.bpj.2009.12.4192.

11.

Structural analysis of B-Box 2 from MuRF1: identification of a novel self-association pattern in a RING-like fold.

Mrosek M, Meier S, Ucurum-Fotiadis Z, von Castelmur E, Hedbom E, Lustig A, Grzesiek S, Labeit D, Labeit S, Mayans O.

Biochemistry. 2008 Oct 7;47(40):10722-30. doi: 10.1021/bi800733z. Epub 2008 Sep 17.

PMID:
18795805
12.

Ultralow-resolution ab initio phasing of filamentous proteins: crystals from a six-Ig fragment of titin as a case study.

Urzhumtsev A, von Castelmur E, Mayans O.

Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):478-86. doi: 10.1107/S0907444908003442. Epub 2008 Apr 19.

PMID:
18453683
13.

A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain.

von Castelmur E, Marino M, Svergun DI, Kreplak L, Ucurum-Fotiadis Z, Konarev PV, Urzhumtsev A, Labeit D, Labeit S, Mayans O.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1186-91. doi: 10.1073/pnas.0707163105. Epub 2008 Jan 22.

14.

Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin.

Mrosek M, Labeit D, Witt S, Heerklotz H, von Castelmur E, Labeit S, Mayans O.

FASEB J. 2007 May;21(7):1383-92. Epub 2007 Jan 10.

PMID:
17215480

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