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Items: 1 to 50 of 67

1.

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response.

de Moel EC, Derksen VFAM, Trouw LA, Bang H, Collée G, Lard LR, Ramiro S, Huizinga TWJ, Allaart CF, Toes REM, van der Woude D.

Arthritis Res Ther. 2019 Jan 18;21(1):28. doi: 10.1186/s13075-019-1815-0.

2.

Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis.

van der Woude D, van der Helm-van Mil AHM.

Best Pract Res Clin Rheumatol. 2018 Apr;32(2):174-187. doi: 10.1016/j.berh.2018.10.005. Epub 2018 Nov 16. Review.

PMID:
30527425
3.

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

de Moel EC, Rozeman EA, Kapiteijn EH, Verdegaal EME, Grummels A, Bakker JA, Huizinga TWJ, Haanen JB, Toes REM, van der Woude D.

Cancer Immunol Res. 2019 Jan;7(1):6-11. doi: 10.1158/2326-6066.CIR-18-0245. Epub 2018 Nov 13.

PMID:
30425107
4.

Autoantibody status is not associated with early treatment response to first-line methotrexate in patients with early rheumatoid arthritis.

Dekkers JS, Bergstra SA, Chopra A, Tikly M, Fonseca JE, Salomon-Escoto K, Huizinga TWJ, van der Woude D.

Rheumatology (Oxford). 2019 Jan 1;58(1):149-153. doi: 10.1093/rheumatology/key263.

PMID:
30204896
5.

Secretory form of rheumatoid arthritis-associated autoantibodies in serum are mainly of the IgM isotype, suggesting a continuous reactivation of autoantibody responses at mucosal surfaces.

van Delft MAM, van der Woude D, Toes REM, Trouw LA.

Ann Rheum Dis. 2019 Jan;78(1):146-148. doi: 10.1136/annrheumdis-2018-213724. Epub 2018 Aug 14. No abstract available.

PMID:
30108046
6.

Anti-Carbamylated Protein Antibodies and Higher Baseline Disease Activity in Rheumatoid Arthritis-A Replication Study in Three Cohorts: Comment on the Article by Truchetet et al.

Derksen VFAM, Trouw LA, Huizinga TWJ, van der Helm-van Mil AHM, Knevel R, Westerlind H, Saevarsdottir S, Ajeganova S, van der Woude D.

Arthritis Rheumatol. 2018 Dec;70(12):2096-2097. doi: 10.1002/art.40678. Epub 2018 Oct 27. No abstract available.

PMID:
30058116
7.

In RA, becoming seronegative over the first year of treatment does not translate to better chances of drug-free remission.

de Moel EC, Derksen VFAM, Trouw LA, Bang H, Goekoop-Ruiterman YPM, Steup-Beekman GM, Huizinga TWJ, Allaart CF, Toes REM, van der Woude D.

Ann Rheum Dis. 2018 Dec;77(12):1836-1838. doi: 10.1136/annrheumdis-2018-213823. Epub 2018 Jul 25. No abstract available.

PMID:
30045852
8.

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals.

Verheul MK, Böhringer S, van Delft MAM, Jones JD, Rigby WFC, Gan RW, Holers VM, Edison JD, Deane KD, Janssen KMJ, Westra J, Brink M, Rantapää-Dahlqvist S, Huizinga TWJ, van der Helm-van Mil AHM, van der Woude D, Toes REM, Trouw LA.

Arthritis Rheumatol. 2018 Nov;70(11):1721-1731. doi: 10.1002/art.40562. Epub 2018 Sep 16.

PMID:
29781231
9.

Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis".

Volkov M, Dekkers J, Loos BG, Bizzarro S, Huizinga TWJ, Praetorius HA, Toes REM, van der Woude D.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaan8349. doi: 10.1126/scitranslmed.aan8349.

PMID:
29563322
10.

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.

de Moel EC, Derksen VFAM, Stoeken G, Trouw LA, Bang H, Goekoop RJ, Speyer I, Huizinga TWJ, Allaart CF, Toes REM, van der Woude D.

Arthritis Res Ther. 2018 Feb 26;20(1):33. doi: 10.1186/s13075-018-1520-4.

11.

The distribution of total vitamin B12, holotranscobalamin, and the active vitamin B12 fraction in the first 5 weeks postpartum.

van der Woude DAA, Pijnenborg JMA, de Vries J, van Wijk EM.

Int J Lab Hematol. 2018 Feb;40(1):72-76. doi: 10.1111/ijlh.12730. Epub 2017 Sep 4.

PMID:
28868811
12.

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients.

van Delft MAM, Verheul MK, Burgers LE, Derksen VFAM, van der Helm-van Mil AHM, van der Woude D, Huizinga TWJ, Toes REM, Trouw LA.

Arthritis Res Ther. 2017 Aug 15;19(1):190. doi: 10.1186/s13075-017-1392-z.

13.

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

Scally SW, Law SC, Ting YT, Heemst JV, Sokolove J, Deutsch AJ, Bridie Clemens E, Moustakas AK, Papadopoulos GK, van der Woude D, Smolik I, Hitchon CA, Robinson DB, Ferucci ED, Bernstein CN, Meng X, Anaparti V, Huizinga T, Kedzierska K, Reid HH, Raychaudhuri S, Toes RE, Rossjohn J, El-Gabalawy H, Thomas R.

Ann Rheum Dis. 2017 Nov;76(11):1915-1923. doi: 10.1136/annrheumdis-2017-211300. Epub 2017 Aug 11.

PMID:
28801345
14.

Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies.

Hermans MPJ, van der Velden D, Montero Cabezas JM, Putter H, Huizinga TWJ, Kuiper J, Toes REM, Schalij MJ, Wouter Jukema J, van der Woude D.

Int J Cardiol. 2017 Aug 1;240:20-24. doi: 10.1016/j.ijcard.2017.04.046. Epub 2017 Apr 25.

PMID:
28487154
15.

The role of autoantibodies in the pathophysiology of rheumatoid arthritis.

Derksen VFAM, Huizinga TWJ, van der Woude D.

Semin Immunopathol. 2017 Jun;39(4):437-446. doi: 10.1007/s00281-017-0627-z. Epub 2017 Apr 27. Review.

16.

Rheumatoid arthritis phenotype at presentation differs depending on the number of autoantibodies present.

Derksen VF, Ajeganova S, Trouw LA, van der Helm-van Mil AH, Hafström I, Huizinga TW, Toes RE, Svensson B, van der Woude D.

Ann Rheum Dis. 2017 Apr;76(4):716-720. doi: 10.1136/annrheumdis-2016-209794. Epub 2016 Nov 9.

PMID:
28283528
17.

The contribution of autoantibodies to post-translationally modified proteins to inflammatory arthritis.

van der Woude D, Toes RE.

Curr Opin Rheumatol. 2017 Mar;29(2):195-200. doi: 10.1097/BOR.0000000000000371. Review.

PMID:
27977623
18.

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

van Wesemael TJ, Ajeganova S, Humphreys J, Terao C, Muhammad A, Symmons DP, MacGregor AJ, Hafström I, Trouw LA, van der Helm-van Mil AH, Huizinga TW, Mimori T, Toes RE, Matsuda F, Svensson B, Verstappen SM, van der Woude D.

Arthritis Res Ther. 2016 Dec 1;18(1):285.

19.

The target of ACPA.

van der Woude D, van der Helm-van Mil AH.

Rheumatology (Oxford). 2016 Oct;55(10):1711-3. doi: 10.1093/rheumatology/kew270. Epub 2016 Jun 30. No abstract available.

PMID:
27371696
20.

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation.

Verheul MK, van Erp SJ, van der Woude D, Levarht EW, Mallat MJ, Verspaget HW, Stolk J, Toes RE, van der Meulen-de Jong AE, Hiemstra PS, van Kooten C, Trouw LA.

Ann Rheum Dis. 2016 Aug;75(8):1575-6. doi: 10.1136/annrheumdis-2016-209248. Epub 2016 Apr 29. No abstract available.

PMID:
27130909
21.

HLA and anti-citrullinated protein antibodies: Building blocks in RA.

van der Woude D, Catrina AI.

Best Pract Res Clin Rheumatol. 2015 Dec;29(6):692-705. doi: 10.1016/j.berh.2016.02.006. Epub 2016 Mar 16. Review.

PMID:
27107507
22.

The role of anticitrullinated protein antibodies in the early stages of rheumatoid arthritis.

Dekkers J, Toes RE, Huizinga TW, van der Woude D.

Curr Opin Rheumatol. 2016 May;28(3):275-81. doi: 10.1097/BOR.0000000000000277. Review.

PMID:
26945334
23.

Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA.

van Heemst J, Hensvold AH, Jiang X, van Steenbergen H, Klareskog L, Huizinga TW, van der Helm-van Mil A, Catrina AI, Toes RE, Lundberg K, van der Woude D.

Ann Rheum Dis. 2016 Oct;75(10):1891-8. doi: 10.1136/annrheumdis-2015-207802. Epub 2015 Dec 29.

PMID:
26715653
24.

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

van Heemst J, Trouw LA, Nogueira L, van Steenbergen HW, van der Helm-van Mil AH, Allaart CF, Serre G, Holmdahl R, Huizinga TW, Toes RE, van der Woude D.

Arthritis Res Ther. 2015 Oct 5;17:276. doi: 10.1186/s13075-015-0786-z.

25.

Marginal genetic effects estimation in family and twin studies using random-effects models.

Tsonaka R, van der Woude D, Houwing-Duistermaat J.

Biometrics. 2015 Dec;71(4):1130-8. doi: 10.1111/biom.12350. Epub 2015 Jul 6.

PMID:
26148843
26.

Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis.

van Heemst J, Jansen DT, Polydorides S, Moustakas AK, Bax M, Feitsma AL, Bontrop-Elferink DG, Baarse M, van der Woude D, Wolbink GJ, Rispens T, Koning F, de Vries RR, Papadopoulos GK, Archontis G, Huizinga TW, Toes RE.

Nat Commun. 2015 May 5;6:6681. doi: 10.1038/ncomms7681.

PMID:
25942574
27.

Fine-mapping the human leukocyte antigen locus in rheumatoid arthritis and other rheumatic diseases: identifying causal amino acid variants?

van Heemst J, Huizinga TJ, van der Woude D, Toes RE.

Curr Opin Rheumatol. 2015 May;27(3):256-61. doi: 10.1097/BOR.0000000000000165. Review.

PMID:
25760279
28.

Health status and quality of life in postpartum women: a systematic review of associated factors.

Van der Woude DA, Pijnenborg JM, de Vries J.

Eur J Obstet Gynecol Reprod Biol. 2015 Feb;185:45-52. doi: 10.1016/j.ejogrb.2014.11.041. Epub 2014 Dec 5. Review.

PMID:
25522118
29.

How undifferentiated arthritis evolves into chronic arthritis.

van der Woude D, Toes RE, Scherer HU.

Best Pract Res Clin Rheumatol. 2014 Aug;28(4):551-64. doi: 10.1016/j.berh.2014.10.013. Epub 2014 Nov 18. Review.

PMID:
25481549
30.

Health status and fatigue of postpartum anemic women: a prospective cohort study.

Van Der Woude D, Pijnenborg JM, Verzijl JM, Van Wijk EM, De Vries J.

Eur J Obstet Gynecol Reprod Biol. 2014 Oct;181:119-23. doi: 10.1016/j.ejogrb.2014.07.028. Epub 2014 Aug 1.

PMID:
25150948
31.

A randomized controlled trial examining the addition of folic acid to iron supplementation in the treatment of postpartum anemia.

Van Der Woude DA, De Vries J, Van Wijk EM, Verzijl JM, Pijnenborg JM.

Int J Gynaecol Obstet. 2014 Aug;126(2):101-5. doi: 10.1016/j.ijgo.2014.02.013. Epub 2014 Apr 13.

PMID:
24839916
32.

HLA and rheumatoid arthritis: how do they connect?

van Heemst J, van der Woude D, Huizinga TW, Toes RE.

Ann Med. 2014 Aug;46(5):304-10. doi: 10.3109/07853890.2014.907097. Epub 2014 May 9. Review.

PMID:
24813459
33.

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

Jiang X, Trouw LA, van Wesemael TJ, Shi J, Bengtsson C, Källberg H, Malmström V, Israelsson L, Hreggvidsdottir H, Verduijn W, Klareskog L, Alfredsson L, Huizinga TW, Toes RE, Lundberg K, van der Woude D.

Ann Rheum Dis. 2014 Oct;73(10):1761-8. doi: 10.1136/annrheumdis-2013-205109. Epub 2014 May 8.

PMID:
24812286
34.

Family studies in the information age.

van der Woude D, Gröndal G, Huizinga TW.

Arthritis Rheum. 2013 Nov;65(11):2762-4. doi: 10.1002/art.38096. No abstract available.

35.

Patients with early arthritis consume less alcohol than controls, regardless of the type of arthritis.

Huidekoper AL, van der Woude D, Knevel R, van der Helm-van Mil AH, Cannegieter SC, Rosendaal FR, Kloppenburg M, Huizinga TW.

Rheumatology (Oxford). 2013 Sep;52(9):1701-7. doi: 10.1093/rheumatology/ket212. Epub 2013 Jun 20.

PMID:
23793744
36.

Pathogenic relevance of anti-citrullinated vimentin antibodies: comment on the article by Montes et al.

van der Woude D, Scherer HU, Huizinga TW, Toes RE.

Arthritis Rheum. 2013 Feb;65(2):541-2. doi: 10.1002/art.37744. No abstract available.

37.

Combining family and twin data in association studies to estimate the noninherited maternal antigens effect.

Balliu B, Tsonaka R, van der Woude D, Boehringer S, Houwing-Duistermaat JJ.

Genet Epidemiol. 2012 Dec;36(8):811-9. doi: 10.1002/gepi.21667. Epub 2012 Jul 31.

PMID:
22851506
38.

An added value for the hemoglobin content in reticulocytes (CHr) and the mean corpuscular volume (MCV) in the diagnosis of iron deficiency in postpartum anemic women.

Ramakers C, van der Woude DA, Verzijl JM, Pijnenborg JM, van Wijk EM.

Int J Lab Hematol. 2012 Oct;34(5):510-6. doi: 10.1111/j.1751-553X.2012.01423.x. Epub 2012 May 1.

PMID:
22548729
39.

Sustained drug-free remission in rheumatoid arthritis after DAS-driven or non-DAS-driven therapy: a comparison of two cohort studies.

van der Woude D, Visser K, Klarenbeek NB, Ronday HK, Peeters AJ, Kerstens PJ, Dijkmans BA, Huizinga TW, van der Helm-van Mil AH, Allaart CF.

Rheumatology (Oxford). 2012 Jun;51(6):1120-8. doi: 10.1093/rheumatology/ker516. Epub 2012 Feb 15.

PMID:
22337939
40.

ACPA (anti-citrullinated protein antibodies) and rheumatoid arthritis.

Toes RE, van der Woude D.

Acta Reumatol Port. 2011 Jul-Sep;36(3):205-7.

41.

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis.

Scherer HU, van der Woude D, Willemze A, Trouw LA, Knevel R, Syversen SW, van der Linden MP, Lie B, Huizinga TW, van der Heijde DM, van der Helm-van Mil AH, Kvien TK, Toes RE.

Ann Rheum Dis. 2011 Aug;70(8):1461-4. doi: 10.1136/ard.2010.146506. Epub 2011 Jun 10.

PMID:
21666230
42.

The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens.

Willemze A, van der Woude D, Ghidey W, Levarht EW, Stoeken-Rijsbergen G, Verduyn W, de Vries RR, Houwing-Duistermaat JJ, Huizinga TW, Trouw LA, Toes RE.

Arthritis Rheum. 2011 Jul;63(7):1823-32. doi: 10.1002/art.30409.

43.

Genetics of ACPA-positive rheumatoid arthritis: the beginning of the end?

de Vries RR, van der Woude D, Houwing JJ, Toes RE.

Ann Rheum Dis. 2011 Mar;70 Suppl 1:i51-4. doi: 10.1136/ard.2010.138040. Review.

PMID:
21339219
44.

Coiling of a vulvar arterio-venous malformation.

Van der Woude DA, Stegeman M, Seelen JL.

BMJ Case Rep. 2011 Dec 1;2011. pii: bcr0320113972. doi: 10.1136/bcr.03.2011.3972.

45.

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens.

Suwannalai P, Scherer HU, van der Woude D, Ioan-Facsinay A, Jol-van der Zijde CM, van Tol MJ, Drijfhout JW, Huizinga TW, Toes RE, Trouw LA.

Ann Rheum Dis. 2011 Feb;70(2):373-9. doi: 10.1136/ard.2010.135509. Epub 2010 Nov 10.

PMID:
21068094
46.

Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis.

van der Woude D, Alemayehu WG, Verduijn W, de Vries RR, Houwing-Duistermaat JJ, Huizinga TW, Toes RE.

Nat Genet. 2010 Oct;42(10):814-6; author reply 816. doi: 10.1038/ng1010-814. No abstract available.

PMID:
20877316
47.

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities.

Ioan-Facsinay A, el-Bannoudi H, Scherer HU, van der Woude D, Ménard HA, Lora M, Trouw LA, Huizinga TW, Toes RE.

Ann Rheum Dis. 2011 Jan;70(1):188-93. doi: 10.1136/ard.2010.131102. Epub 2010 Aug 24.

PMID:
20736390
48.

Long-term impact of delay in assessment of patients with early arthritis.

van der Linden MP, le Cessie S, Raza K, van der Woude D, Knevel R, Huizinga TW, van der Helm-van Mil AH.

Arthritis Rheum. 2010 Dec;62(12):3537-46. doi: 10.1002/art.27692.

49.

Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis.

van der Woude D, Rantapää-Dahlqvist S, Ioan-Facsinay A, Onnekink C, Schwarte CM, Verpoort KN, Drijfhout JW, Huizinga TW, Toes RE, Pruijn GJ.

Ann Rheum Dis. 2010 Aug;69(8):1554-61. doi: 10.1136/ard.2009.124537. Epub 2010 May 6.

PMID:
20448290
50.

The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis.

van der Woude D, Syversen SW, van der Voort EI, Verpoort KN, Goll GL, van der Linden MP, van der Helm-van Mil AH, van der Heijde DM, Huizinga TW, Kvien TK, Toes RE.

Ann Rheum Dis. 2010 Jun;69(6):1110-6. doi: 10.1136/ard.2009.116384. Epub 2010 May 3.

PMID:
20439289

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