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Items: 1 to 50 of 121

1.

Simultaneous Determination of Biliary and Intestinal Cholesterol Secretion Reveals That CETP (Cholesteryl Ester Transfer Protein) Alters Elimination Route in Mice.

Li J, Pijut SS, Wang Y, Ji A, Kaur R, Temel RE, van der Westhuyzen DR, Graf GA.

Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):1986-1995. doi: 10.1161/ATVBAHA.119.312952. Epub 2019 Aug 29.

PMID:
31462090
2.

Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice.

Kim MH, de Beer MC, Wroblewski JM, Charnigo RJ, Ji A, Webb NR, de Beer FC, van der Westhuyzen DR.

J Lipid Res. 2016 Jun;57(6):969-79. doi: 10.1194/jlr.M062174. Epub 2016 Mar 27.

3.

GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice.

Wang Y, Su K, Sabeva NS, Ji A, van der Westhuyzen DR, Foufelle F, Gao X, Graf GA.

Metabolism. 2015 Nov;64(11):1435-43. doi: 10.1016/j.metabol.2015.08.005. Epub 2015 Aug 15.

4.

Impact of phospholipid transfer protein on nascent high-density lipoprotein formation and remodeling.

Ji A, Wroblewski JM, Webb NR, van der Westhuyzen DR.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1910-6. doi: 10.1161/ATVBAHA.114.303533. Epub 2014 Jul 24.

5.

Minimally oxidized LDL inhibits macrophage selective cholesteryl ester uptake and native LDL-induced foam cell formation.

Meyer JM, Ji A, Cai L, van der Westhuyzen DR.

J Lipid Res. 2014 Aug;55(8):1648-56. doi: 10.1194/jlr.M044644. Epub 2014 Jun 2.

6.

Deficiency of endogenous acute phase serum amyloid A does not affect atherosclerotic lesions in apolipoprotein E-deficient mice.

De Beer MC, Wroblewski JM, Noffsinger VP, Rateri DL, Howatt DA, Balakrishnan A, Ji A, Shridas P, Thompson JC, van der Westhuyzen DR, Tannock LR, Daugherty A, Webb NR, De Beer FC.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):255-61. doi: 10.1161/ATVBAHA.113.302247. Epub 2013 Nov 21.

7.

New developments in selective cholesteryl ester uptake.

Meyer JM, Graf GA, van der Westhuyzen DR.

Curr Opin Lipidol. 2013 Oct;24(5):386-92. doi: 10.1097/MOL.0b013e3283638042. Review.

8.

The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A.

de Beer MC, Wroblewski JM, Noffsinger VP, Ji A, Meyer JM, van der Westhuyzen DR, de Beer FC, Webb NR.

J Lipids. 2013;2013:283486. doi: 10.1155/2013/283486. Epub 2013 Jan 30.

9.

High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation.

Meyer JM, Ji A, Cai L, van der Westhuyzen DR.

J Lipid Res. 2012 Oct;53(10):2081-91. doi: 10.1194/jlr.M026534. Epub 2012 Jul 25.

10.

The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation.

Su K, Sabeva NS, Liu J, Wang Y, Bhatnagar S, van der Westhuyzen DR, Graf GA.

J Biol Chem. 2012 Aug 17;287(34):28564-75. doi: 10.1074/jbc.M112.360081. Epub 2012 Jun 19.

11.

Scavenger receptor CD36 expression contributes to adipose tissue inflammation and cell death in diet-induced obesity.

Cai L, Wang Z, Ji A, Meyer JM, van der Westhuyzen DR.

PLoS One. 2012;7(5):e36785. doi: 10.1371/journal.pone.0036785. Epub 2012 May 16.

12.

Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages.

Cai L, Wang Z, Meyer JM, Ji A, van der Westhuyzen DR.

J Lipid Res. 2012 Aug;53(8):1472-81. doi: 10.1194/jlr.M023234. Epub 2012 May 15.

13.

Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI.

Ji A, Wroblewski JM, Cai L, de Beer MC, Webb NR, van der Westhuyzen DR.

J Lipid Res. 2012 Mar;53(3):446-55. doi: 10.1194/jlr.M017079. Epub 2011 Dec 20.

14.

Nascent HDL formation by hepatocytes is reduced by the concerted action of serum amyloid A and endothelial lipase.

Wroblewski JM, Jahangiri A, Ji A, de Beer FC, van der Westhuyzen DR, Webb NR.

J Lipid Res. 2011 Dec;52(12):2255-61. doi: 10.1194/jlr.M017681. Epub 2011 Sep 27.

15.

Scavenger receptor SR-BI in macrophage lipid metabolism.

Ji A, Meyer JM, Cai L, Akinmusire A, de Beer MC, Webb NR, van der Westhuyzen DR.

Atherosclerosis. 2011 Jul;217(1):106-12. doi: 10.1016/j.atherosclerosis.2011.03.017. Epub 2011 Apr 9.

16.

ATP binding cassette G1-dependent cholesterol efflux during inflammation.

de Beer MC, Ji A, Jahangiri A, Vaughan AM, de Beer FC, van der Westhuyzen DR, Webb NR.

J Lipid Res. 2011 Feb;52(2):345-53. doi: 10.1194/jlr.M012328. Epub 2010 Dec 7.

17.

Impact of serum amyloid A on high density lipoprotein composition and levels.

de Beer MC, Webb NR, Wroblewski JM, Noffsinger VP, Rateri DL, Ji A, van der Westhuyzen DR, de Beer FC.

J Lipid Res. 2010 Nov;51(11):3117-25. doi: 10.1194/jlr.M005413. Epub 2010 Jul 27.

18.

Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E.

Neyen C, Plüddemann A, Roversi P, Thomas B, Cai L, van der Westhuyzen DR, Sim RB, Gordon S.

Biochemistry. 2009 Dec 22;48(50):11858-71. doi: 10.1021/bi9013769.

19.

SR-BI selective lipid uptake: subsequent metabolism of acute phase HDL.

de Beer MC, Webb NR, Whitaker NL, Wroblewski JM, Jahangiri A, van der Westhuyzen DR, de Beer FC.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1298-303. doi: 10.1161/ATVBAHA.109.186502. Epub 2009 Mar 19.

20.

Mammalian Wnt3a is released on lipoprotein particles.

Neumann S, Coudreuse DY, van der Westhuyzen DR, Eckhardt ER, Korswagen HC, Schmitz G, Sprong H.

Traffic. 2009 Mar;10(3):334-43. doi: 10.1111/j.1600-0854.2008.00872.x.

21.

Syndecan-4 mediates macrophage uptake of group V secretory phospholipase A2-modified LDL.

Boyanovsky BB, Shridas P, Simons M, van der Westhuyzen DR, Webb NR.

J Lipid Res. 2009 Apr;50(4):641-50. doi: 10.1194/jlr.M800450-JLR200. Epub 2008 Dec 3.

22.

HDL remodeling during the acute phase response.

Jahangiri A, de Beer MC, Noffsinger V, Tannock LR, Ramaiah C, Webb NR, van der Westhuyzen DR, de Beer FC.

Arterioscler Thromb Vasc Biol. 2009 Feb;29(2):261-7. doi: 10.1161/ATVBAHA.108.178681. Epub 2008 Nov 13.

23.

Adiponectin reduces plasma triglyceride by increasing VLDL triglyceride catabolism.

Qiao L, Zou C, van der Westhuyzen DR, Shao J.

Diabetes. 2008 Jul;57(7):1824-33. doi: 10.2337/db07-0435. Epub 2008 Mar 28.

24.

SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance.

Cai L, Ji A, de Beer FC, Tannock LR, van der Westhuyzen DR.

J Clin Invest. 2008 Jan;118(1):364-75.

25.

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI.

Sun B, Boyanovsky BB, Connelly MA, Shridas P, van der Westhuyzen DR, Webb NR.

J Lipid Res. 2007 Dec;48(12):2560-70. Epub 2007 Sep 17.

26.

HDL cholesterol transport during inflammation.

van der Westhuyzen DR, de Beer FC, Webb NR.

Curr Opin Lipidol. 2007 Apr;18(2):147-51. Review.

PMID:
17353662
27.

Human serum amyloid A protein inhibits hepatitis C virus entry into cells.

Cai Z, Cai L, Jiang J, Chang KS, van der Westhuyzen DR, Luo G.

J Virol. 2007 Jun;81(11):6128-33. Epub 2007 Feb 28.

28.

Phosphatidylinositol-3-kinase regulates scavenger receptor class B type I subcellular localization and selective lipid uptake in hepatocytes.

Shetty S, Eckhardt ER, Post SR, van der Westhuyzen DR.

Arterioscler Thromb Vasc Biol. 2006 Sep;26(9):2125-31. Epub 2006 Jun 22.

PMID:
16794223
29.

Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts.

Sun B, Eckhardt ER, Shetty S, van der Westhuyzen DR, Webb NR.

J Lipid Res. 2006 Aug;47(8):1700-13. Epub 2006 May 16.

30.

SR-BI-mediated high density lipoprotein (HDL) endocytosis leads to HDL resecretion facilitating cholesterol efflux.

Pagler TA, Rhode S, Neuhofer A, Laggner H, Strobl W, Hinterndorfer C, Volf I, Pavelka M, Eckhardt ER, van der Westhuyzen DR, Schütz GJ, Stangl H.

J Biol Chem. 2006 Apr 21;281(16):11193-204. Epub 2006 Feb 16.

31.

High density lipoprotein endocytosis by scavenger receptor SR-BII is clathrin-dependent and requires a carboxyl-terminal dileucine motif.

Eckhardt ER, Cai L, Shetty S, Zhao Z, Szanto A, Webb NR, Van der Westhuyzen DR.

J Biol Chem. 2006 Feb 17;281(7):4348-53. Epub 2005 Dec 19.

32.

Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I.

van der Westhuyzen DR, Cai L, de Beer MC, de Beer FC.

J Biol Chem. 2005 Oct 28;280(43):35890-5. Epub 2005 Aug 23.

33.

SR-BI-mediated selective lipid uptake segregates apoA-I and apoA-II catabolism.

de Beer MC, van der Westhuyzen DR, Whitaker NL, Webb NR, de Beer FC.

J Lipid Res. 2005 Oct;46(10):2143-50. Epub 2005 Aug 1.

34.
35.

Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice.

Out R, Hoekstra M, de Jager SC, de Vos P, van der Westhuyzen DR, Webb NR, Van Eck M, Biessen EA, Van Berkel TJ.

J Lipid Res. 2005 Jun;46(6):1172-81. Epub 2005 Mar 16.

36.

Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptake.

Cai L, de Beer MC, de Beer FC, van der Westhuyzen DR.

J Biol Chem. 2005 Jan 28;280(4):2954-61. Epub 2004 Nov 23.

37.

Low-density lipoprotein from apolipoprotein E-deficient mice induces macrophage lipid accumulation in a CD36 and scavenger receptor class A-dependent manner.

Zhao Z, de Beer MC, Cai L, Asmis R, de Beer FC, de Villiers WJ, van der Westhuyzen DR.

Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):168-73. Epub 2004 Oct 28.

PMID:
15514202
38.

Remodeling of HDL remnants generated by scavenger receptor class B type I.

Webb NR, de Beer MC, Asztalos BF, Whitaker N, van der Westhuyzen DR, de Beer FC.

J Lipid Res. 2004 Sep;45(9):1666-73. Epub 2004 Jun 21.

39.

ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36.

de Beer MC, Castellani LW, Cai L, Stromberg AJ, de Beer FC, van der Westhuyzen DR.

J Lipid Res. 2004 Apr;45(4):706-15. Epub 2004 Jan 16.

40.

Soluble LDL-R are formed by cell surface cleavage in response to phorbol esters.

Begg MJ, Sturrock ED, van der Westhuyzen DR.

Eur J Biochem. 2004 Feb;271(3):524-33.

41.

High density lipoprotein uptake by scavenger receptor SR-BII.

Eckhardt ER, Cai L, Sun B, Webb NR, van der Westhuyzen DR.

J Biol Chem. 2004 Apr 2;279(14):14372-81. Epub 2004 Jan 15.

42.

Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells.

Cai L, Eckhardt ER, Shi W, Zhao Z, Nasser M, de Villiers WJ, van der Westhuyzen DR.

J Lipid Res. 2004 Feb;45(2):253-62. Epub 2003 Nov 16.

43.

ApoB-containing lipoproteins in apoE-deficient mice are not metabolized by the class B scavenger receptor BI.

Webb NR, de Beer MC, de Beer FC, van der Westhuyzen DR.

J Lipid Res. 2004 Feb;45(2):272-80. Epub 2003 Oct 16.

44.

Macrophage-expressed group IIA secretory phospholipase A2 increases atherosclerotic lesion formation in LDL receptor-deficient mice.

Webb NR, Bostrom MA, Szilvassy SJ, van der Westhuyzen DR, Daugherty A, de Beer FC.

Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):263-8.

PMID:
12588769
45.

Lack of a direct role for macrosialin in oxidized LDL metabolism.

de Beer MC, Zhao Z, Webb NR, van der Westhuyzen DR, de Villiers WJ.

J Lipid Res. 2003 Apr;44(4):674-85. Epub 2003 Jan 16.

46.

The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake.

Webb NR, Cai L, Ziemba KS, Yu J, Kindy MS, van der Westhuyzen DR, de Beer FC.

J Lipid Res. 2002 Nov;43(11):1890-8.

47.

Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice.

Webb NR, de Beer MC, Yu J, Kindy MS, Daugherty A, van der Westhuyzen DR, de Beer FC.

J Lipid Res. 2002 Sep;43(9):1421-8.

48.

CD36 does not play a direct role in HDL or LDL metabolism.

de Villiers WJ, Cai L, Webb NR, de Beer MC, van der Westhuyzen DR, de Beer FC.

J Lipid Res. 2001 Aug;42(8):1231-8.

49.

Apolipoprotein A-II modulates the binding and selective lipid uptake of reconstituted high density lipoprotein by scavenger receptor BI.

de Beer MC, Durbin DM, Cai L, Mirocha N, Jonas A, Webb NR, de Beer FC, van Der Westhuyzen DR.

J Biol Chem. 2001 May 11;276(19):15832-9. Epub 2001 Feb 9.

50.

Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E.

Goti D, Hrzenjak A, Levak-Frank S, Frank S, van der Westhuyzen DR, Malle E, Sattler W.

J Neurochem. 2001 Jan;76(2):498-508.

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