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Items: 1 to 50 of 81

1.

Influence of different isoflurane anesthesia protocols on murine cerebral hemodynamics measured with pseudo-continuous arterial spin labeling.

Munting LP, Derieppe MPP, Suidgeest E, Denis de Senneville B, Wells JA, van der Weerd L.

NMR Biomed. 2019 Jun 7:e4105. doi: 10.1002/nbm.4105. [Epub ahead of print]

PMID:
31172591
2.

Osteopontin and phospho-SMAD2/3 are associated with calcification of vessels in D-CAA, an hereditary cerebral amyloid angiopathy.

Grand Moursel L, van der Graaf LM, Bulk M, van Roon-Mom WMC, van der Weerd L.

Brain Pathol. 2019 Mar 13. doi: 10.1111/bpa.12721. [Epub ahead of print]

PMID:
30868685
3.

Imaging beta amyloid aggregation and iron accumulation in Alzheimer's disease using quantitative susceptibility mapping MRI.

Gong NJ, Dibb R, Bulk M, van der Weerd L, Liu C.

Neuroimage. 2019 May 1;191:176-185. doi: 10.1016/j.neuroimage.2019.02.019. Epub 2019 Feb 7.

PMID:
30739060
4.

Normal Aging Brain Collection Amsterdam (NABCA): A comprehensive collection of postmortem high-field imaging, neuropathological and morphometric datasets of non-neurological controls.

Jonkman LE, Graaf YG, Bulk M, Kaaij E, Pouwels PJW, Barkhof F, Rozemuller AJM, van der Weerd L, Geurts JJG, van de Berg WDJ.

Neuroimage Clin. 2019;22:101698. doi: 10.1016/j.nicl.2019.101698. Epub 2019 Jan 29.

5.

7T MRI allows detection of disturbed cortical lamination of the medial temporal lobe in patients with Alzheimer's disease.

Kenkhuis B, Jonkman LE, Bulk M, Buijs M, Boon BDC, Bouwman FH, Geurts JJG, van de Berg WDJ, van der Weerd L.

Neuroimage Clin. 2019;21:101665. doi: 10.1016/j.nicl.2019.101665. Epub 2019 Jan 5.

6.

Natriuretic Peptides in Post-mortem Brain Tissue and Cerebrospinal Fluid of Non-demented Humans and Alzheimer's Disease Patients.

Mahinrad S, Bulk M, van der Velpen I, Mahfouz A, van Roon-Mom W, Fedarko N, Yasar S, Sabayan B, van Heemst D, van der Weerd L.

Front Neurosci. 2018 Nov 26;12:864. doi: 10.3389/fnins.2018.00864. eCollection 2018.

7.

Cerebral Amyloid Angiopathy With Vascular Iron Accumulation and Calcification.

Bulk M, Moursel LG, van der Graaf LM, van Veluw SJ, Greenberg SM, van Duinen SG, van Buchem MA, van Rooden S, van der Weerd L.

Stroke. 2018 Sep;49(9):2081-2087. doi: 10.1161/STROKEAHA.118.021872.

PMID:
30354978
8.

Voluntary exercise improves muscle function and does not exacerbate muscle and heart pathology in aged Duchenne muscular dystrophy mice.

Kogelman B, Putker K, Hulsker M, Tanganyika-de Winter C, van der Weerd L, Aartsma-Rus A, van Putten M.

J Mol Cell Cardiol. 2018 Dec;125:29-38. doi: 10.1016/j.yjmcc.2018.10.008. Epub 2018 Oct 16.

9.

Multicenter reproducibility of quantitative susceptibility mapping in a gadolinium phantom using MEDI+0 automatic zero referencing.

Deh K, Kawaji K, Bulk M, Van Der Weerd L, Lind E, Spincemaille P, McCabe Gillen K, Van Auderkerke J, Wang Y, Nguyen TD.

Magn Reson Med. 2019 Feb;81(2):1229-1236. doi: 10.1002/mrm.27410. Epub 2018 Oct 4.

PMID:
30284727
10.

Postmortem T2*- Weighted MRI Imaging of Cortical Iron Reflects Severity of Alzheimer's Disease.

Bulk M, Kenkhuis B, van der Graaf LM, Goeman JJ, Natté R, van der Weerd L.

J Alzheimers Dis. 2018;65(4):1125-1137. doi: 10.3233/JAD-180317.

11.

Quantitative comparison of different iron forms in the temporal cortex of Alzheimer patients and control subjects.

Bulk M, van der Weerd L, Breimer W, Lebedev N, Webb A, Goeman JJ, Ward RJ, Huber M, Oosterkamp TH, Bossoni L.

Sci Rep. 2018 May 2;8(1):6898. doi: 10.1038/s41598-018-25021-7.

12.

Brain Transcriptomic Analysis of Hereditary Cerebral Hemorrhage With Amyloidosis-Dutch Type.

Grand Moursel L, van Roon-Mom WMC, Kiełbasa SM, Mei H, Buermans HPJ, van der Graaf LM, Hettne KM, de Meijer EJ, van Duinen SG, Laros JFJ, van Buchem MA, 't Hoen PAC, van der Maarel SM, van der Weerd L.

Front Aging Neurosci. 2018 Apr 13;10:102. doi: 10.3389/fnagi.2018.00102. eCollection 2018.

13.

Postmortem MRI and histology demonstrate differential iron accumulation and cortical myelin organization in early- and late-onset Alzheimer's disease.

Bulk M, Abdelmoula WM, Nabuurs RJA, van der Graaf LM, Mulders CWH, Mulder AA, Jost CR, Koster AJ, van Buchem MA, Natté R, Dijkstra J, van der Weerd L.

Neurobiol Aging. 2018 Feb;62:231-242. doi: 10.1016/j.neurobiolaging.2017.10.017. Epub 2017 Oct 28.

PMID:
29195086
14.

9.4T and 17.6T MRI of Retinoblastoma: Ex Vivo evaluation of microstructural anatomy and disease extent compared with histopathology.

de Jong MC, de Graaf P, Pouwels PJW, Beenakker JW, Jansen RW, Geurts JJG, Moll AC, Castelijns JA, van der Valk P, van der Weerd L.

J Magn Reson Imaging. 2018 Jun;47(6):1487-1497. doi: 10.1002/jmri.25913. Epub 2017 Nov 28.

PMID:
29193569
15.

Transit time mapping in the mouse brain using time-encoded pCASL.

Hirschler L, Munting LP, Khmelinskii A, Teeuwisse WM, Suidgeest E, Warnking JM, van der Weerd L, Barbier EL, van Osch MJP.

NMR Biomed. 2018 Feb;31(2). doi: 10.1002/nbm.3855. Epub 2017 Nov 21.

PMID:
29160952
16.

Cortical Iron Reflects Severity of Alzheimer's Disease.

van Duijn S, Bulk M, van Duinen SG, Nabuurs RJA, van Buchem MA, van der Weerd L, Natté R.

J Alzheimers Dis. 2017;60(4):1533-1545. doi: 10.3233/JAD-161143.

17.

Human-brain ferritin studied by muon spin rotation: a pilot study.

Bossoni L, Grand Moursel L, Bulk M, Simon BG, Webb A, van der Weerd L, Huber M, Carretta P, Lascialfari A, Oosterkamp TH.

J Phys Condens Matter. 2017 Oct 18;29(41):415801. doi: 10.1088/1361-648X/aa80b3. Epub 2017 Sep 5.

PMID:
28872048
18.

TGFβ pathway deregulation and abnormal phospho-SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis-Dutch type.

Grand Moursel L, Munting LP, van der Graaf LM, van Duinen SG, Goumans MTH, Ueberham U, Natté R, van Buchem MA, van Roon-Mom WMC, van der Weerd L.

Brain Pathol. 2018 Jul;28(4):495-506. doi: 10.1111/bpa.12533. Epub 2017 Jun 12.

PMID:
28557134
19.

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes.

Casewell NR, Visser JC, Baumann K, Dobson J, Han H, Kuruppu S, Morgan M, Romilio A, Weisbecker V, Mardon K, Ali SA, Debono J, Koludarov I, Que I, Bird GC, Cooke GM, Nouwens A, Hodgson WC, Wagstaff SC, Cheney KL, Vetter I, van der Weerd L, Richardson MK, Fry BG.

Curr Biol. 2017 May 22;27(10):1549-1550. doi: 10.1016/j.cub.2017.05.009. No abstract available.

20.

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes.

Casewell NR, Visser JC, Baumann K, Dobson J, Han H, Kuruppu S, Morgan M, Romilio A, Weisbecker V, Mardon K, Ali SA, Debono J, Koludarov I, Que I, Bird GC, Cooke GM, Nouwens A, Hodgson WC, Wagstaff SC, Cheney KL, Vetter I, van der Weerd L, Richardson MK, Fry BG.

Curr Biol. 2017 Apr 24;27(8):1184-1191. doi: 10.1016/j.cub.2017.02.067. Epub 2017 Mar 30. Erratum in: Curr Biol. 2017 May 22;27(10):1549-1550.

21.

A novel approach to quantify different iron forms in ex-vivo human brain tissue.

Kumar P, Bulk M, Webb A, van der Weerd L, Oosterkamp TH, Huber M, Bossoni L.

Sci Rep. 2016 Dec 12;6:38916. doi: 10.1038/srep38916.

22.

Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds.

Nabuurs RJ, Kapoerchan VV, Metaxas A, Hafith S, de Backer M, Welling MM, Jiskoot W, van den Nieuwendijk AM, Windhorst AD, Overkleeft HS, van Buchem MA, Overhand M, van der Weerd L.

Bioorg Med Chem. 2016 Dec 1;24(23):6139-6148. doi: 10.1016/j.bmc.2016.05.022. Epub 2016 May 18.

PMID:
27838168
23.

Continuous infusion of manganese improves contrast and reduces side effects in manganese-enhanced magnetic resonance imaging studies.

Poole DS, Doorenweerd N, Plomp JJ, Mahfouz A, Reinders MJT, van der Weerd L.

Neuroimage. 2017 Feb 15;147:1-9. doi: 10.1016/j.neuroimage.2016.09.030. Epub 2016 Oct 21.

PMID:
27777173
24.

The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation.

Rutten JW, Klever RR, Hegeman IM, Poole DS, Dauwerse HG, Broos LA, Breukel C, Aartsma-Rus AM, Verbeek JS, van der Weerd L, van Duinen SG, van den Maagdenberg AM, Lesnik Oberstein SA.

Acta Neuropathol Commun. 2015 Dec 29;3:89. doi: 10.1186/s40478-015-0268-1.

25.

Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.

Dorresteijn B, Rotman M, Faber D, Schravesande R, Suidgeest E, van der Weerd L, van der Maarel SM, Verrips CT, El Khattabi M.

FEBS J. 2015 Sep;282(18):3618-31. doi: 10.1111/febs.13367. Epub 2015 Jul 22.

26.

Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.

Rotman M, Welling MM, van den Boogaard ML, Moursel LG, van der Graaf LM, van Buchem MA, van der Maarel SM, van der Weerd L.

Nucl Med Biol. 2015 Aug;42(8):695-702. doi: 10.1016/j.nucmedbio.2015.03.003. Epub 2015 Mar 18.

27.

Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease.

Rotman M, Welling MM, Bunschoten A, de Backer ME, Rip J, Nabuurs RJ, Gaillard PJ, van Buchem MA, van der Maarel SM, van der Weerd L.

J Control Release. 2015 Apr 10;203:40-50. doi: 10.1016/j.jconrel.2015.02.012. Epub 2015 Feb 7.

PMID:
25668771
28.

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease.

Leonhard WN, Zandbergen M, Veraar K, van den Berg S, van der Weerd L, Breuning M, de Heer E, Peters DJ.

J Am Soc Nephrol. 2015 Jun;26(6):1322-33. doi: 10.1681/ASN.2013080864. Epub 2014 Oct 31.

29.

Interactive local super-resolution reconstruction of whole-body MRI mouse data: a pilot study with applications to bone and kidney metastases.

Dzyubachyk O, Khmelinskii A, Plenge E, Kok P, Snoeks TJ, Poot DH, Löwik CW, Botha CP, Niessen WJ, van der Weerd L, Meijering E, Lelieveldt BP.

PLoS One. 2014 Sep 29;9(9):e108730. doi: 10.1371/journal.pone.0108730. eCollection 2014.

30.

In vivo bioluminescence imaging of vascular remodeling after stroke.

Adamczak JM, Schneider G, Nelles M, Que I, Suidgeest E, van der Weerd L, Löwik C, Hoehn M.

Front Cell Neurosci. 2014 Sep 5;8:274. doi: 10.3389/fncel.2014.00274. eCollection 2014.

31.

Three-dimensional inversion recovery manganese-enhanced MRI of mouse brain using super-resolution reconstruction to visualize nuclei involved in higher brain function.

Poole DS, Plenge E, Poot DH, Lakke EA, Niessen WJ, Meijering E, van der Weerd L.

NMR Biomed. 2014 Jul;27(7):749-59. doi: 10.1002/nbm.3108. Epub 2014 May 10.

PMID:
24817644
32.

Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands.

Nabuurs RJ, Kapoerchan VV, Metaxas A, de Jongh S, de Backer M, Welling MM, Jiskoot W, Windhorst AD, Overkleeft HS, van Buchem MA, Overhand M, van der Weerd L.

Bioorg Med Chem. 2014 Apr 15;22(8):2469-81. doi: 10.1016/j.bmc.2014.02.054. Epub 2014 Mar 7.

PMID:
24657049
33.

Potential role of antimicrobial peptides in the early onset of Alzheimer's disease.

Welling MM, Nabuurs RJ, van der Weerd L.

Alzheimers Dement. 2015 Jan;11(1):51-7. doi: 10.1016/j.jalz.2013.12.020. Epub 2014 Mar 15.

PMID:
24637300
34.

Low dystrophin levels in heart can delay heart failure in mdx mice.

van Putten M, van der Pijl EM, Hulsker M, Verhaart IE, Nadarajah VD, van der Weerd L, Aartsma-Rus A.

J Mol Cell Cardiol. 2014 Apr;69:17-23. doi: 10.1016/j.yjmcc.2014.01.009. Epub 2014 Jan 29.

35.

Mouse models to study the effect of cardiovascular risk factors on brain structure and cognition.

Bink DI, Ritz K, Aronica E, van der Weerd L, Daemen MJ.

J Cereb Blood Flow Metab. 2013 Nov;33(11):1666-84. doi: 10.1038/jcbfm.2013.140. Epub 2013 Aug 21. Review.

36.

Cardiac dysfunction in pneumovirus-induced lung injury in mice.

Bem RA, van den Berg E, Suidgeest E, van der Weerd L, van Woensel JB, Grotenhuis HB.

Pediatr Crit Care Med. 2013 Jun;14(5):e243-9. doi: 10.1097/PCC.0b013e31828a7f9b.

PMID:
23867445
37.

Scavenger receptor-AI-targeted iron oxide nanoparticles for in vivo MRI detection of atherosclerotic lesions.

Segers FM, den Adel B, Bot I, van der Graaf LM, van der Veer EP, Gonzalez W, Raynal I, de Winther M, Wodzig WK, Poelmann RE, van Berkel TJ, van der Weerd L, Biessen EA.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1812-9. doi: 10.1161/ATVBAHA.112.300707. Epub 2013 Jun 6.

PMID:
23744990
38.

Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles.

Fry BG, Undheim EA, Ali SA, Jackson TN, Debono J, Scheib H, Ruder T, Morgenstern D, Cadwallader L, Whitehead D, Nabuurs R, van der Weerd L, Vidal N, Roelants K, Hendrikx I, Gonzalez SP, Koludarov I, Jones A, King GF, Antunes A, Sunagar K.

Mol Cell Proteomics. 2013 Jul;12(7):1881-99. doi: 10.1074/mcp.M112.023143. Epub 2013 Apr 1.

39.

Self-gated CINE MRI for combined contrast-enhanced imaging and wall-stiffness measurements of murine aortic atherosclerotic lesions.

den Adel B, van der Graaf LM, Strijkers GJ, Lamb HJ, Poelmann RE, van der Weerd L.

PLoS One. 2013;8(3):e57299. doi: 10.1371/journal.pone.0057299. Epub 2013 Mar 5.

40.

Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice.

van Putten M, Hulsker M, Young C, Nadarajah VD, Heemskerk H, van der Weerd L, 't Hoen PA, van Ommen GJ, Aartsma-Rus AM.

FASEB J. 2013 Jun;27(6):2484-95. doi: 10.1096/fj.12-224170. Epub 2013 Mar 4.

41.

Molecular Magnetic Resonance Imaging for the Detection of Vulnerable Plaques: Is It Possible?: Retracted.

den Adel B, Daemen MJ, Poelmann RE, van der Weerd L.

Arterioscler Thromb Vasc Biol. 2013 Apr 10. [Epub ahead of print] Retraction in: Arterioscler Thromb Vasc Biol. 2013 May;33(5):e117.

PMID:
23413424
42.

MR microscopy of human amyloid-β deposits: characterization of parenchymal amyloid, diffuse plaques, and vascular amyloid.

Nabuurs RJ, Natté R, de Ronde FM, Hegeman-Kleinn I, Dijkstra J, van Duinen SG, Webb AG, Rozemuller AJ, van Buchem MA, van der Weerd L.

J Alzheimers Dis. 2013;34(4):1037-49. doi: 10.3233/JAD-122215.

PMID:
23340037
43.

Contrast enhancement by lipid-based MRI contrast agents in mouse atherosclerotic plaques; a longitudinal study.

den Adel B, van der Graaf LM, Que I, Strijkers GJ, Löwik CW, Poelmann RE, van der Weerd L.

Contrast Media Mol Imaging. 2013 Jan-Feb;8(1):63-71. doi: 10.1002/cmmi.1496.

PMID:
23109394
44.

Histological validation of iron-oxide and gadolinium based MRI contrast agents in experimental atherosclerosis: the do's and don't's.

den Adel B, Bovens SM, te Boekhorst B, Strijkers GJ, Poelmann RE, van der Weerd L, Pasterkamp G.

Atherosclerosis. 2012 Dec;225(2):274-80. doi: 10.1016/j.atherosclerosis.2012.07.028. Epub 2012 Jul 27. Review.

PMID:
22882907
45.

In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease.

Nabuurs RJ, Rutgers KS, Welling MM, Metaxas A, de Backer ME, Rotman M, Bacskai BJ, van Buchem MA, van der Maarel SM, van der Weerd L.

PLoS One. 2012;7(6):e38284. doi: 10.1371/journal.pone.0038284. Epub 2012 Jun 4.

46.

Super-resolution methods in MRI: can they improve the trade-off between resolution, signal-to-noise ratio, and acquisition time?

Plenge E, Poot DH, Bernsen M, Kotek G, Houston G, Wielopolski P, van der Weerd L, Niessen WJ, Meijering E.

Magn Reson Med. 2012 Dec;68(6):1983-93. doi: 10.1002/mrm.24187. Epub 2012 Feb 1.

47.

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.

Verhaart IE, van Duijn RJ, den Adel B, Roest AA, Verschuuren JJ, Aartsma-Rus A, van der Weerd L.

Neuromuscul Disord. 2012 May;22(5):418-26. doi: 10.1016/j.nmd.2011.10.025. Epub 2011 Dec 29.

48.

Pretreatment with interferon-γ enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis.

Duijvestein M, Wildenberg ME, Welling MM, Hennink S, Molendijk I, van Zuylen VL, Bosse T, Vos AC, de Jonge-Muller ES, Roelofs H, van der Weerd L, Verspaget HW, Fibbe WE, te Velde AA, van den Brink GR, Hommes DW.

Stem Cells. 2011 Oct;29(10):1549-58. doi: 10.1002/stem.698.

49.

MRI in animal models of psychiatric disorders.

Poole DS, Oitzl MS, van der Weerd L.

Methods Mol Biol. 2011;771:309-35. doi: 10.1007/978-1-61779-219-9_17.

PMID:
21874486
50.

Volumetry and other quantitative measurements to assess the rodent brain.

Scheenstra A, Dijkstra J, van der Weerd L.

Methods Mol Biol. 2011;771:277-91. doi: 10.1007/978-1-61779-219-9_15.

PMID:
21874484

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