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Items: 12


The role of neuraminidase 1 and 2 in glycoprotein Ibα-mediated integrin αIIbβ3 activation.

van der Wal DE, Davis AM, Mach M, Marks DC.

Haematologica. 2019 Jul 4. pii: haematol.2019.215830. doi: 10.3324/haematol.2019.215830. [Epub ahead of print]


Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia.

Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai ZM, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H.

Nat Commun. 2015 Jul 17;6:7737. doi: 10.1038/ncomms8737.


Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia.

Urbanus RT, van der Wal DE, Koekman CA, Huisman A, van den Heuvel DJ, Gerritsen HC, Deckmyn H, Akkerman JW, Schutgens RE, Gitz E.

Haematologica. 2013 Jul;98(7):e70-2. doi: 10.3324/haematol.2013.087874. Epub 2013 May 28. No abstract available.


Fc-independent phagocytosis: implications for IVIG and other therapies in immune-mediated thrombocytopenia.

Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H.

Cardiovasc Hematol Disord Drug Targets. 2013 Mar 1;13(1):50-8. Review.


Arachidonic acid depletion extends survival of cold-stored platelets by interfering with the [glycoprotein Ibα--14-3-3ζ] association.

van der Wal DE, Gitz E, Du VX, Lo KS, Koekman CA, Versteeg S, Akkerman JW.

Haematologica. 2012 Oct;97(10):1514-22. doi: 10.3324/haematol.2011.059956. Epub 2012 Feb 27.


Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies.

Zeng Q, Zhu L, Tao L, Bao J, Yang M, Simpson EK, Li C, van der Wal DE, Chen P, Spring CM, Wang M, Zhang L, Ruan C, Hou M, Xia R, Ni H.

Am J Hematol. 2012 Feb;87(2):206-8. doi: 10.1002/ajh.22211. Epub 2011 Dec 3.


The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.

Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H.

J Clin Invest. 2011 Nov;121(11):4537-47. doi: 10.1172/JCI57850. Epub 2011 Oct 24.


Platelet apoptosis by cold-induced glycoprotein Ibα clustering.

van der Wal DE, DU VX, Lo KS, Rasmussen JT, Verhoef S, Akkerman JW.

J Thromb Haemost. 2010 Nov;8(11):2554-62. doi: 10.1111/j.1538-7836.2010.04043.x.


Role of glycoprotein Ibalpha mobility in platelet function.

van der Wal DE, Verhoef S, Schutgens RE, Peters M, Wu Y, Akkerman JW.

Thromb Haemost. 2010 May;103(5):1033-43. doi: 10.1160/TH09-11-0751. Epub 2010 Mar 9.


Downregulation of platelet responsiveness upon contact with LDL by the protein-tyrosine phosphatases SHP-1 and SHP-2.

Korporaal SJ, Koekman CA, Verhoef S, van der Wal DE, Bezemer M, Van Eck M, Akkerman JW.

Arterioscler Thromb Vasc Biol. 2009 Mar;29(3):372-9. doi: 10.1161/ATVBAHA.108.173278. Epub 2008 Dec 18.


Myosin heavy chain fibre type composition in foals: analyses at the mRNA and protein level.

Eizema K, van der Wal DE, van den Burg MM, Dingboom EG, Everts ME.

Equine Vet J Suppl. 2006 Aug;(36):316-21.


Differential expression of calcineurin and SR Ca2+ handling proteins in equine muscle fibers during early postnatal growth.

Eizema K, van der Wal DE, van den Burg MM, de Jonge HW, Everts ME.

J Histochem Cytochem. 2007 Mar;55(3):247-54. Epub 2006 Nov 13.


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