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Items: 1 to 50 of 164

1.

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.

van den Berg BM, Wang G, Boels MGS, Avramut MC, Jansen E, Sol WMPJ, Lebrin F, Jan van Zonneveld A, de Koning EJP, Vink H, Gröne HJ, Carmeliet P, van der Vlag J, Rabelink TJ.

J Am Soc Nephrol. 2019 Jul 15. pii: ASN.2019020192. doi: 10.1681/ASN.2019020192. [Epub ahead of print]

PMID:
31308073
2.

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions.

Kuppe C, Leuchtle K, Wagner A, Kabgani N, Saritas T, Puelles VG, Smeets B, Hakroush S, van der Vlag J, Boor P, Schiffer M, Gröne HJ, Fogo A, Floege J, Moeller MJ.

Kidney Int. 2019 Jul;96(1):80-93. doi: 10.1016/j.kint.2019.01.037. Epub 2019 Feb 27.

PMID:
31029503
3.

C3 glomerulopathy - understanding a rare complement-driven renal disease.

Smith RJH, Appel GB, Blom AM, Cook HT, D'Agati VD, Fakhouri F, Fremeaux-Bacchi V, Józsi M, Kavanagh D, Lambris JD, Noris M, Pickering MC, Remuzzi G, de Córdoba SR, Sethi S, Van der Vlag J, Zipfel PF, Nester CM.

Nat Rev Nephrol. 2019 Mar;15(3):129-143. doi: 10.1038/s41581-018-0107-2. Review.

PMID:
30692664
4.

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M.

Cell Death Differ. 2019 Mar;26(3):395-408. doi: 10.1038/s41418-018-0261-x. Epub 2019 Jan 8. Review.

PMID:
30622307
5.

Vascular bioengineering of scaffolds derived from human discarded transplant kidneys using human pluripotent stem cell-derived endothelium.

Leuning DG, Witjas FMR, Maanaoui M, de Graaf AMA, Lievers E, Geuens T, Avramut CM, Wiersma LE, van den Berg CW, Sol WMPJ, de Boer H, Wang G, LaPointe VLS, van der Vlag J, van Kooten C, van den Berg BM, Little MH, Engelse MA, Rabelink TJ.

Am J Transplant. 2019 May;19(5):1328-1343. doi: 10.1111/ajt.15200. Epub 2019 Jan 10.

6.

Differential binding of chemokines CXCL1, CXCL2 and CCL2 to mouse glomerular endothelial cells reveals specificity for distinct heparan sulfate domains.

van Gemst JJ, Kouwenberg M, Rops ALWMM, van Kuppevelt TH, Berden JH, Rabelink TJ, Loeven MA, van der Vlag J.

PLoS One. 2018 Sep 24;13(9):e0201560. doi: 10.1371/journal.pone.0201560. eCollection 2018.

7.

Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development.

Uijtdewilligen PJE, Versteeg EM, van de Westerlo EMA, van der Vlag J, Daamen WF, van Kuppevelt TH.

Biomed Res Int. 2018 Aug 29;2018:9873471. doi: 10.1155/2018/9873471. eCollection 2018.

8.

Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation.

Pieterse E, Rother N, Yanginlar C, Gerretsen J, Boeltz S, Munoz LE, Herrmann M, Pickkers P, Hilbrands LB, van der Vlag J.

Ann Rheum Dis. 2018 Dec;77(12):1790-1798. doi: 10.1136/annrheumdis-2018-213223. Epub 2018 Aug 17.

PMID:
30120096
9.

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy.

Luo W, Olaru F, Miner JH, Beck LH Jr, van der Vlag J, Thurman JM, Borza DB.

Front Immunol. 2018 Jun 22;9:1433. doi: 10.3389/fimmu.2018.01433. eCollection 2018.

10.

The Calcium-Dependent Protease Calpain-1 Links TRPC6 Activity to Podocyte Injury.

Verheijden KAT, Sonneveld R, Bakker-van Bebber M, Wetzels JFM, van der Vlag J, Nijenhuis T.

J Am Soc Nephrol. 2018 Aug;29(8):2099-2109. doi: 10.1681/ASN.2016111248. Epub 2018 Jun 28.

PMID:
29954830
11.

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus.

Biermann MHC, Boeltz S, Pieterse E, Knopf J, Rech J, Bilyy R, van der Vlag J, Tincani A, Distler JHW, Krönke G, Schett GA, Herrmann M, Muñoz LE.

Front Immunol. 2018 May 7;9:989. doi: 10.3389/fimmu.2018.00989. eCollection 2018.

12.

Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity.

Büll C, Boltje TJ, Balneger N, Weischer SM, Wassink M, van Gemst JJ, Bloemendal VR, Boon L, van der Vlag J, Heise T, den Brok MH, Adema GJ.

Cancer Res. 2018 Jul 1;78(13):3574-3588. doi: 10.1158/0008-5472.CAN-17-3376. Epub 2018 Apr 27.

13.

Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.

Rops ALWMM, Jansen E, van der Schaaf A, Pieterse E, Rother N, Hofstra J, Dijkman HBPM, van de Logt AE, Wetzels J, van der Vlag J, van Spriel AB.

Kidney Int. 2018 Jun;93(6):1356-1366. doi: 10.1016/j.kint.2018.01.005. Epub 2018 Mar 16.

PMID:
29551516
14.

IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene.

Thiyagarajan D, Pedersen HL, Seredkina N, Horvei KD, Arranz L, Sonneveld R, Nijenhuis T, van der Vlag J, Rekvig OP.

Front Cell Dev Biol. 2018 Feb 6;6:7. doi: 10.3389/fcell.2018.00007. eCollection 2018.

15.

A Novel Choroidal Endothelial Cell Line Has a Decreased Affinity for the Age-Related Macular Degeneration-Associated Complement Factor H Variant 402H.

Loeven MA, van Gemst JJ, Schophuizen CMS, Tilakaratna V, van den Heuvel LP, Day AJ, Klevering BJ, van der Vlag J.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):722-730. doi: 10.1167/iovs.IOVS-17-22893.

PMID:
29392318
16.

Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.

Goetz L, Laskowski J, Renner B, Pickering MC, Kulik L, Klawitter J, Stites E, Christians U, van der Vlag J, Ravichandran K, Holers VM, Thurman JM.

Eur J Immunol. 2018 May;48(5):791-802. doi: 10.1002/eji.201747240. Epub 2018 Feb 22.

17.

CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis.

Eymael J, Sharma S, Loeven MA, Wetzels JF, Mooren F, Florquin S, Deegens JK, Willemsen BK, Sharma V, van Kuppevelt TH, Bakker MA, Ostendorf T, Moeller MJ, Dijkman HB, Smeets B, van der Vlag J.

Kidney Int. 2018 Mar;93(3):626-642. doi: 10.1016/j.kint.2017.09.020. Epub 2017 Dec 21.

PMID:
29276101
18.

Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice.

de Groot T, Damen L, Kosse L, Alsady M, Doty R, Baumgarten R, Sheehan S, van der Vlag J, Korstanje R, Deen PMT.

PLoS One. 2017 Dec 15;12(12):e0189485. doi: 10.1371/journal.pone.0189485. eCollection 2017.

19.

Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis.

Rother N, Pieterse E, Lubbers J, Hilbrands L, van der Vlag J.

Front Immunol. 2017 Sep 14;8:1136. doi: 10.3389/fimmu.2017.01136. eCollection 2017.

20.

Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.

Boels MGS, Koudijs A, Avramut MC, Sol WMPJ, Wang G, van Oeveren-Rietdijk AM, van Zonneveld AJ, de Boer HC, van der Vlag J, van Kooten C, Eulberg D, van den Berg BM, IJpelaar DHT, Rabelink TJ.

Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22.

21.

Leukocyte Bim deficiency does not impact atherogenesis in ldlr -/- mice, despite a pronounced induction of autoimmune inflammation.

Temmerman L, Westra MM, Bot I, van Vlijmen BJM, van Bree N, Bot M, Habets KLL, Keulers TGH, van der Vlag J, Cotter TG, van Berkel TJC, Biessen EAL.

Sci Rep. 2017 Jun 8;7(1):3086. doi: 10.1038/s41598-017-02771-4.

22.

Neutrophil Extracellular Traps Drive Endothelial-to-Mesenchymal Transition.

Pieterse E, Rother N, Garsen M, Hofstra JM, Satchell SC, Hoffmann M, Loeven MA, Knaapen HK, van der Heijden OWH, Berden JHM, Hilbrands LB, van der Vlag J.

Arterioscler Thromb Vasc Biol. 2017 Jul;37(7):1371-1379. doi: 10.1161/ATVBAHA.117.309002. Epub 2017 May 11.

PMID:
28495931
23.

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.

Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB.

PLoS One. 2017 Feb 24;12(2):e0168981. doi: 10.1371/journal.pone.0168981. eCollection 2017.

24.

Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.

Rabelink TJ, van den Berg BM, Garsen M, Wang G, Elkin M, van der Vlag J.

Nat Rev Nephrol. 2017 Apr;13(4):201-212. doi: 10.1038/nrneph.2017.6. Epub 2017 Feb 6. Review.

PMID:
28163306
25.

Direct Observation of Enhanced Nitric Oxide in a Murine Model of Diabetic Nephropathy.

Boels MG, van Faassen EE, Avramut MC, van der Vlag J, van den Berg BM, Rabelink TJ.

PLoS One. 2017 Jan 19;12(1):e0170065. doi: 10.1371/journal.pone.0170065. eCollection 2017.

26.

Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals.

Pieterse E, Jeremic I, Czegley C, Weidner D, Biermann MH, Veissi S, Maueröder C, Schauer C, Bilyy R, Dumych T, Hoffmann M, Munoz LE, Bengtsson AA, Schett G, van der Vlag J, Herrmann M.

Sci Rep. 2016 Dec 5;6:38229. doi: 10.1038/srep38229.

27.

RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues.

van Gemst JJ, Loeven MA, de Graaf MJ, Berden JH, Rabelink TJ, Smit CH, van der Vlag J.

PLoS One. 2016 Nov 29;11(11):e0167336. doi: 10.1371/journal.pone.0167336. eCollection 2016.

28.

Sildenafil Prevents Podocyte Injury via PPAR-γ-Mediated TRPC6 Inhibition.

Sonneveld R, Hoenderop JG, Isidori AM, Henique C, Dijkman HB, Berden JH, Tharaux PL, van der Vlag J, Nijenhuis T.

J Am Soc Nephrol. 2017 May;28(5):1491-1505. doi: 10.1681/ASN.2015080885. Epub 2016 Nov 28.

29.

Neutrophils Discriminate between Lipopolysaccharides of Different Bacterial Sources and Selectively Release Neutrophil Extracellular Traps.

Pieterse E, Rother N, Yanginlar C, Hilbrands LB, van der Vlag J.

Front Immunol. 2016 Nov 4;7:484. eCollection 2016.

30.

Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis.

Dieker J, Berden JH, Bakker M, Briand JP, Muller S, Voll R, Sjöwall C, Herrmann M, Hilbrands LB, van der Vlag J.

PLoS One. 2016 Oct 25;11(10):e0165373. doi: 10.1371/journal.pone.0165373. eCollection 2016.

31.

Urinary MicroRNA as Biomarker in Renal Transplantation.

van de Vrie M, Deegens JK, Eikmans M, van der Vlag J, Hilbrands LB.

Am J Transplant. 2017 May;17(5):1160-1166. doi: 10.1111/ajt.14082. Epub 2016 Nov 10. Review.

32.

Cathepsin L is crucial for the development of early experimental diabetic nephropathy.

Garsen M, Rops AL, Dijkman H, Willemsen B, van Kuppevelt TH, Russel FG, Rabelink TJ, Berden JH, Reinheckel T, van der Vlag J.

Kidney Int. 2016 Nov;90(5):1012-1022. doi: 10.1016/j.kint.2016.06.035. Epub 2016 Aug 26.

PMID:
27575559
33.

Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype.

Kouwenberg M, Jacobs CW, van der Vlag J, Hilbrands LB.

PLoS One. 2016 Aug 15;11(8):e0159986. doi: 10.1371/journal.pone.0159986. eCollection 2016.

34.

Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria.

Garsen M, Rops AL, Li J, van Beneden K, van den Branden C, Berden JH, Rabelink TJ, van der Vlag J.

PLoS One. 2016 Aug 9;11(8):e0160894. doi: 10.1371/journal.pone.0160894. eCollection 2016.

35.

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.

Boels MG, Avramut MC, Koudijs A, Dane MJ, Lee DH, van der Vlag J, Koster AJ, van Zonneveld AJ, van Faassen E, Gröne HJ, van den Berg BM, Rabelink TJ.

Diabetes. 2016 Aug;65(8):2429-39. doi: 10.2337/db15-1413. Epub 2016 Mar 25.

36.

Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx.

Garsen M, Lenoir O, Rops AL, Dijkman HB, Willemsen B, van Kuppevelt TH, Rabelink TJ, Berden JH, Tharaux PL, van der Vlag J.

J Am Soc Nephrol. 2016 Dec;27(12):3545-3551. Epub 2016 Mar 29.

37.

Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis.

Garsen M, Benner M, Dijkman HB, van Kuppevelt TH, Li JP, Rabelink TJ, Vlodavsky I, Berden JH, Rops AL, Elkin M, van der Vlag J.

Am J Pathol. 2016 Apr;186(4):805-15. doi: 10.1016/j.ajpath.2015.12.008. Epub 2016 Feb 9.

PMID:
26873445
38.

1,25-Vitamin D3 Deficiency Induces Albuminuria.

Sonneveld R, Hoenderop JG, Stavenuiter AW, Ferrantelli E, Baltissen MP, Dijkman HB, Florquin S, Rops AL, Wetzels JF, Berden JH, van der Vlag J, Nijenhuis T.

Am J Pathol. 2016 Apr;186(4):794-804. doi: 10.1016/j.ajpath.2015.11.015. Epub 2016 Feb 3.

PMID:
26851346
39.

Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro.

Loeven MA, Rops AL, Lehtinen MJ, van Kuppevelt TH, Daha MR, Smith RJ, Bakker M, Berden JH, Rabelink TJ, Jokiranta TS, van der Vlag J.

J Biol Chem. 2016 Mar 4;291(10):4974-81. doi: 10.1074/jbc.M115.702506. Epub 2016 Jan 4.

40.

Cracking the pathogenesis of cocaine-induced vasculitis.

Pieterse E, van der Vlag J.

Rheumatology (Oxford). 2017 Apr 1;56(4):503-505. doi: 10.1093/rheumatology/kew381. No abstract available.

PMID:
28339525
41.

Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus.

Rother N, van der Vlag J.

Front Immunol. 2015 Nov 30;6:610. doi: 10.3389/fimmu.2015.00610. eCollection 2015. Review.

42.

Reactivity in ELISA with DNA-loaded nucleosomes in patients with proliferative lupus nephritis.

Dieker J, Schlumberger W, McHugh N, Hamann P, van der Vlag J, Berden JH.

Mol Immunol. 2015 Nov;68(1):20-4. doi: 10.1016/j.molimm.2015.06.004.

PMID:
26597199
43.

Circulating Apoptotic Microparticles in Systemic Lupus Erythematosus Patients Drive the Activation of Dendritic Cell Subsets and Prime Neutrophils for NETosis.

Dieker J, Tel J, Pieterse E, Thielen A, Rother N, Bakker M, Fransen J, Dijkman HB, Berden JH, de Vries JM, Hilbrands LB, van der Vlag J.

Arthritis Rheumatol. 2016 Feb;68(2):462-72. doi: 10.1002/art.39417.

44.

Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology.

Lensen JF, van der Vlag J, Versteeg EM, Wetzels JF, van den Heuvel LP, Berden JH, van Kuppevelt TH, Rops AL.

PLoS One. 2015 Aug 31;10(9):e0134946. doi: 10.1371/journal.pone.0134946. eCollection 2015.

45.

Increased expression of lysosome membrane protein 2 in glomeruli of patients with idiopathic membranous nephropathy.

Rood IM, Merchant ML, Wilkey DW, Zhang T, Zabrouskov V, van der Vlag J, Dijkman HB, Willemsen BK, Wetzels JF, Klein JB, Deegens JK.

Proteomics. 2015 Nov;15(21):3722-30. doi: 10.1002/pmic.201500127. Epub 2015 Sep 28.

PMID:
26304790
46.

Vitamin D attenuates proteinuria by inhibition of heparanase expression in the podocyte.

Garsen M, Sonneveld R, Rops AL, Huntink S, van Kuppevelt TH, Rabelink TJ, Hoenderop JG, Berden JH, Nijenhuis T, van der Vlag J.

J Pathol. 2015 Dec;237(4):472-81. doi: 10.1002/path.4593. Epub 2015 Aug 31.

PMID:
26202309
47.

Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice.

Dieker J, Hilbrands L, Thielen A, Dijkman H, Berden JH, van der Vlag J.

Arthritis Res Ther. 2015 Apr 16;17:103. doi: 10.1186/s13075-015-0617-2.

48.

A microscopic view on the renal endothelial glycocalyx.

Dane MJ, van den Berg BM, Lee DH, Boels MG, Tiemeier GL, Avramut MC, van Zonneveld AJ, van der Vlag J, Vink H, Rabelink TJ.

Am J Physiol Renal Physiol. 2015 May 1;308(9):F956-66. doi: 10.1152/ajprenal.00532.2014. Epub 2015 Feb 11. Review.

49.

The role of heparan sulfate as determining pathogenic factor in complement factor H-associated diseases.

Loeven MA, Rops AL, Berden JH, Daha MR, Rabelink TJ, van der Vlag J.

Mol Immunol. 2015 Feb;63(2):203-8. doi: 10.1016/j.molimm.2014.08.005. Epub 2014 Sep 20. Review.

PMID:
25246018
50.

TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy.

Hofstra JM, Coenen MJ, Schijvenaars MM, Berden JH, van der Vlag J, Hoefsloot LH, Knoers NV, Wetzels JF, Nijenhuis T.

PLoS One. 2014 Jul 14;9(7):e102065. doi: 10.1371/journal.pone.0102065. eCollection 2014.

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