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Items: 42

1.

Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease.

Burggraaf MJ, Speer A, Meijers AS, Ummels R, van der Sar AM, Korotkov KV, Bitter W, Kuijl C.

MBio. 2019 Oct 29;10(5). pii: e01951-19. doi: 10.1128/mBio.01951-19.

2.

CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity.

Majolée J, Pronk MCA, Jim KK, van Bezu JSM, van der Sar AM, Hordijk PL, Kovačević I.

Sci Rep. 2019 May 31;9(1):8131. doi: 10.1038/s41598-019-44595-4.

3.

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF.

Phan TH, van Leeuwen LM, Kuijl C, Ummels R, van Stempvoort G, Rubio-Canalejas A, Piersma SR, Jiménez CR, van der Sar AM, Houben ENG, Bitter W.

PLoS Pathog. 2018 Aug 13;14(8):e1007247. doi: 10.1371/journal.ppat.1007247. eCollection 2018 Aug.

4.

Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry.

Bruinen AL, Fisher GL, Balez R, van der Sar AM, Ooi L, Heeren RMA.

J Am Soc Mass Spectrom. 2018 Aug;29(8):1571-1581. doi: 10.1007/s13361-018-1979-x. Epub 2018 Jun 12.

5.

Mycobacteria employ two different mechanisms to cross the blood-brain barrier.

van Leeuwen LM, Boot M, Kuijl C, Picavet DI, van Stempvoort G, van der Pol SMA, de Vries HE, van der Wel NN, van der Kuip M, van Furth AM, van der Sar AM, Bitter W.

Cell Microbiol. 2018 Sep;20(9):e12858. doi: 10.1111/cmi.12858. Epub 2018 May 30.

6.

A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5.

van Leeuwen LM, Evans RJ, Jim KK, Verboom T, Fang X, Bojarczuk A, Malicki J, Johnston SA, van der Sar AM.

Biol Open. 2018 Feb 2;7(2). pii: bio030494. doi: 10.1242/bio.030494.

7.

Correction: First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).

Yoon S, Mitra S, Wyse C, Alnabulsi A, Zou J, Weerdenburg EM, van der Sar AM, Wang D, Secombes CJ, Bird S.

PLoS One. 2016 Dec 21;11(12):e0169149. doi: 10.1371/journal.pone.0169149. eCollection 2016.

8.

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model.

Jim KK, Engelen-Lee J, van der Sar AM, Bitter W, Brouwer MC, van der Ende A, Veening JW, van de Beek D, Vandenbroucke-Grauls CM.

J Neuroinflammation. 2016 Aug 19;13(1):188. doi: 10.1186/s12974-016-0655-y.

9.

Prophylactic administration of chicken cathelicidin-2 boosts zebrafish embryonic innate immunity.

Schneider VA, van Dijk A, van der Sar AM, Kraaij MD, Veldhuizen EJ, Haagsman HP.

Dev Comp Immunol. 2016 Jul;60:108-14. doi: 10.1016/j.dci.2016.02.023. Epub 2016 Feb 23.

10.

First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio).

Yoon S, Mitra S, Wyse C, Alnabulsi A, Zou J, Weerdenburg EM, van der Sar AM, Wang D, Secombes CJ, Bird S.

PLoS One. 2015 Jun 17;10(6):e0126378. doi: 10.1371/journal.pone.0126378. eCollection 2015. Erratum in: PLoS One. 2016 Dec 21;11(12 ):e0169149.

11.

Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts.

Weerdenburg EM, Abdallah AM, Rangkuti F, Abd El Ghany M, Otto TD, Adroub SA, Molenaar D, Ummels R, Ter Veen K, van Stempvoort G, van der Sar AM, Ali S, Langridge GC, Thomson NR, Pain A, Bitter W.

Infect Immun. 2015 May;83(5):1778-88. doi: 10.1128/IAI.03050-14. Epub 2015 Feb 17.

12.

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.

Torraca V, Cui C, Boland R, Bebelman JP, van der Sar AM, Smit MJ, Siderius M, Spaink HP, Meijer AH.

Dis Model Mech. 2015 Mar;8(3):253-69. doi: 10.1242/dmm.017756. Epub 2015 Jan 8.

13.

Animal models of tuberculosis: zebrafish.

van Leeuwen LM, van der Sar AM, Bitter W.

Cold Spring Harb Perspect Med. 2014 Nov 20;5(3):a018580. doi: 10.1101/cshperspect.a018580. Review.

14.

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.

van Leeuwen LM, van der Kuip M, Youssef SA, de Bruin A, Bitter W, van Furth AM, van der Sar AM.

Dis Model Mech. 2014 Sep;7(9):1111-22. doi: 10.1242/dmm.015453. Epub 2014 Jul 4.

15.

Assessing Pseudomonas virulence with nonmammalian host: zebrafish.

Llamas MA, van der Sar AM.

Methods Mol Biol. 2014;1149:709-21. doi: 10.1007/978-1-4939-0473-0_55.

PMID:
24818945
16.

Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo.

Romano M, van de Weerd R, Brouwer FC, Roviello GN, Lacroix R, Sparrius M, van den Brink-van Stempvoort G, Maaskant JJ, van der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R.

Structure. 2014 May 6;22(5):719-30. doi: 10.1016/j.str.2014.01.014. Epub 2014 Apr 3.

17.

Towards a new combination therapy for tuberculosis with next generation benzothiazinones.

Makarov V, Lechartier B, Zhang M, Neres J, van der Sar AM, Raadsen SA, Hartkoorn RC, Ryabova OB, Vocat A, Decosterd LA, Widmer N, Buclin T, Bitter W, Andries K, Pojer F, Dyson PJ, Cole ST.

EMBO Mol Med. 2014 Mar;6(3):372-83. doi: 10.1002/emmm.201303575. Epub 2014 Feb 5.

18.

Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.

van der Woude AD, Stoop EJ, Stiess M, Wang S, Ummels R, van Stempvoort G, Piersma SR, Cascioferro A, Jiménez CR, Houben EN, Luirink J, Pieters J, van der Sar AM, Bitter W.

Cell Microbiol. 2014 Feb;16(2):280-95. doi: 10.1111/cmi.12221. Epub 2013 Nov 6.

PMID:
24119166
19.

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity.

Stoop EJ, Mishra AK, Driessen NN, van Stempvoort G, Bouchier P, Verboom T, van Leeuwen LM, Sparrius M, Raadsen SA, van Zon M, van der Wel NN, Besra GS, Geurtsen J, Bitter W, Appelmelk BJ, van der Sar AM.

Cell Microbiol. 2013 Dec;15(12):2093-108. doi: 10.1111/cmi.12175. Epub 2013 Aug 22.

20.

Galectin-4 Reduces Migration and Metastasis Formation of Pancreatic Cancer Cells.

Belo AI, van der Sar AM, Tefsen B, van Die I.

PLoS One. 2013 Jun 18;8(6):e65957. doi: 10.1371/journal.pone.0065957. Print 2013.

21.

Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis.

Driessen NN, Boshoff HI, Maaskant JJ, Gilissen SA, Vink S, van der Sar AM, Vandenbroucke-Grauls CM, Bewley CA, Appelmelk BJ, Geurtsen J.

J Immunol. 2012 Oct 1;189(7):3585-92. Epub 2012 Aug 31.

22.

Tubercle bacilli rely on a type VII army for pathogenicity.

Stoop EJ, Bitter W, van der Sar AM.

Trends Microbiol. 2012 Oct;20(10):477-84. doi: 10.1016/j.tim.2012.07.001. Epub 2012 Aug 2. Review.

PMID:
22858229
23.

Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum.

van der Woude AD, Sarkar D, Bhatt A, Sparrius M, Raadsen SA, Boon L, Geurtsen J, van der Sar AM, Luirink J, Houben EN, Besra GS, Bitter W.

J Biol Chem. 2012 Jun 8;287(24):20417-29. doi: 10.1074/jbc.M111.336461. Epub 2012 Apr 13.

24.

Infection of zebrafish embryos with intracellular bacterial pathogens.

Benard EL, van der Sar AM, Ellett F, Lieschke GJ, Spaink HP, Meijer AH.

J Vis Exp. 2012 Mar 15;(61). pii: 3781. doi: 10.3791/3781.

25.

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

Weerdenburg EM, Abdallah AM, Mitra S, de Punder K, van der Wel NN, Bird S, Appelmelk BJ, Bitter W, van der Sar AM.

Cell Microbiol. 2012 May;14(5):728-39. doi: 10.1111/j.1462-5822.2012.01755.x. Epub 2012 Feb 15.

PMID:
22256857
26.

Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation.

Abdallah AM, Bestebroer J, Savage ND, de Punder K, van Zon M, Wilson L, Korbee CJ, van der Sar AM, Ottenhoff TH, van der Wel NN, Bitter W, Peters PJ.

J Immunol. 2011 Nov 1;187(9):4744-53. doi: 10.4049/jimmunol.1101457. Epub 2011 Sep 28.

27.

Identification of a glycosyltransferase from Mycobacterium marinum involved in addition of a caryophyllose moiety in lipooligosaccharides.

Sarkar D, Sidhu M, Singh A, Chen J, Lammas DA, van der Sar AM, Besra GS, Bhatt A.

J Bacteriol. 2011 May;193(9):2336-40. doi: 10.1128/JB.00065-11. Epub 2011 Mar 4.

28.

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component.

Stoop EJ, Schipper T, Rosendahl Huber SK, Nezhinsky AE, Verbeek FJ, Gurcha SS, Besra GS, Vandenbroucke-Grauls CM, Bitter W, van der Sar AM.

Dis Model Mech. 2011 Jul;4(4):526-36. doi: 10.1242/dmm.006676. Epub 2011 Mar 3.

29.

Discovery of zebrafish (Danio rerio) interleukin-23 alpha (IL-23α) chain, a subunit important for the formation of IL-23, a cytokine involved in the development of Th17 cells and inflammation.

Holt A, Mitra S, van der Sar AM, Alnabulsi A, Secombes CJ, Bird S.

Mol Immunol. 2011 Apr;48(8):981-91. doi: 10.1016/j.molimm.2010.12.012. Epub 2011 Feb 16.

PMID:
21324528
30.

The role of gamma interferon in innate immunity in the zebrafish embryo.

Sieger D, Stein C, Neifer D, van der Sar AM, Leptin M.

Dis Model Mech. 2009 Nov-Dec;2(11-12):571-81. doi: 10.1242/dmm.003509. Epub 2009 Sep 24.

31.

Zebrafish development and regeneration: new tools for biomedical research.

Brittijn SA, Duivesteijn SJ, Belmamoune M, Bertens LF, Bitter W, de Bruijn JD, Champagne DL, Cuppen E, Flik G, Vandenbroucke-Grauls CM, Janssen RA, de Jong IM, de Kloet ER, Kros A, Meijer AH, Metz JR, van der Sar AM, Schaaf MJ, Schulte-Merker S, Spaink HP, Tak PP, Verbeek FJ, Vervoordeldonk MJ, Vonk FJ, Witte F, Yuan H, Richardson MK.

Int J Dev Biol. 2009;53(5-6):835-50. doi: 10.1387/ijdb.082615sb. Review.

32.

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components.

van der Sar AM, Spaink HP, Zakrzewska A, Bitter W, Meijer AH.

Mol Immunol. 2009 Jul;46(11-12):2317-32. doi: 10.1016/j.molimm.2009.03.024. Epub 2009 May 5.

PMID:
19409617
33.

Transmission of Mycobacterium marinum from fish to a very young child.

Doedens RA, van der Sar AM, Bitter W, Schölvinck EH.

Pediatr Infect Dis J. 2008 Jan;27(1):81-3.

PMID:
18162949
34.

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.

Appelmelk BJ, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, Larrouy-Maumus G, Gurcha SS, Movahedzadeh F, Geurtsen J, Brown EJ, Eysink Smeets MM, Besra GS, Willemsen PT, Lowary TL, van Kooyk Y, Maaskant JJ, Stoker NG, van der Ley P, Puzo G, Vandenbroucke-Grauls CM, Wieland CW, van der Poll T, Geijtenbeek TB, van der Sar AM, Bitter W.

Cell Microbiol. 2008 Apr;10(4):930-44. Epub 2007 Dec 5.

PMID:
18070119
35.

Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish.

Meijer AH, van der Sar AM, Cunha C, Lamers GE, Laplante MA, Kikuta H, Bitter W, Becker TS, Spaink HP.

Dev Comp Immunol. 2008;32(1):36-49. Epub 2007 May 22.

PMID:
17553562
36.

MyD88 innate immune function in a zebrafish embryo infection model.

van der Sar AM, Stockhammer OW, van der Laan C, Spaink HP, Bitter W, Meijer AH.

Infect Immun. 2006 Apr;74(4):2436-41.

37.

Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection.

Meijer AH, Verbeek FJ, Salas-Vidal E, Corredor-Adámez M, Bussman J, van der Sar AM, Otto GW, Geisler R, Spaink HP.

Mol Immunol. 2005 Jun;42(10):1185-203. Epub 2005 Jan 12.

PMID:
15829308
38.

Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence.

van der Sar AM, Abdallah AM, Sparrius M, Reinders E, Vandenbroucke-Grauls CM, Bitter W.

Infect Immun. 2004 Nov;72(11):6306-12.

39.

A star with stripes: zebrafish as an infection model.

van der Sar AM, Appelmelk BJ, Vandenbroucke-Grauls CM, Bitter W.

Trends Microbiol. 2004 Oct;12(10):451-7. Review. No abstract available.

PMID:
15381194
40.

Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections.

van der Sar AM, Musters RJ, van Eeden FJ, Appelmelk BJ, Vandenbroucke-Grauls CM, Bitter W.

Cell Microbiol. 2003 Sep;5(9):601-11.

PMID:
12925130
41.

Eye defects in receptor protein-tyrosine phosphatase alpha knock-down zebrafish.

van der Sar AM, Zivković D, den Hertog J.

Dev Dyn. 2002 Mar;223(2):292-7.

42.

Pleiotropic effects of zebrafish protein-tyrosine phosphatase-1B on early embryonic development.

van der Sar AM, de Fockert J, Betist M, Zivković D, den Hertog J.

Int J Dev Biol. 1999 Nov;43(8):785-94.

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