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Items: 34

1.

Inflammation and TGF-β Signaling Differ between Abdominal Aneurysms and Occlusive Disease.

IJpma A, Te Riet L, van de Luijtgaarden KM, van Heijningen PM, Burger J, Majoor-Krakauer D, Rouwet EV, Essers J, Verhagen HJM, van der Pluijm I.

J Cardiovasc Dev Dis. 2019 Nov 1;6(4). pii: E38. doi: 10.3390/jcdd6040038.

2.

Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.

Burger J, van Vliet N, van Heijningen P, Kumra H, Kremers GJ, Alves M, van Cappellen G, Yanagisawa H, Reinhardt DP, Kanaar R, van der Pluijm I, Essers J.

Cell Signal. 2019 Jun;58:65-78. doi: 10.1016/j.cellsig.2019.02.008. Epub 2019 Mar 4. Review.

PMID:
30844428
3.

Gestational jet lag predisposes to later-life skeletal and cardiac disease.

Chaves I, van der Eerden B, Boers R, Boers J, Streng AA, Ridwan Y, Schreuders-Koedam M, Vermeulen M, van der Pluijm I, Essers J, Gribnau J, Reiss IKM, van der Horst GTJ.

Chronobiol Int. 2019 May;36(5):657-671. doi: 10.1080/07420528.2019.1579734. Epub 2019 Feb 22.

PMID:
30793958
4.

Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.

van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J.

Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150.

5.

Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1Δ/- mice.

Wu H, van Thiel BS, Bautista-Niño PK, Reiling E, Durik M, Leijten FPJ, Ridwan Y, Brandt RMC, van Steeg H, Dollé MET, Vermeij WP, Hoeijmakers JHJ, Essers J, van der Pluijm I, Danser AHJ, Roks AJM.

Clin Sci (Lond). 2017 Jul 13;131(15):1941-1953. doi: 10.1042/CS20170026. Print 2017 Aug 1.

PMID:
28620011
6.

Brain Renin-Angiotensin System: Does It Exist?

van Thiel BS, Góes Martini A, Te Riet L, Severs D, Uijl E, Garrelds IM, Leijten FPJ, van der Pluijm I, Essers J, Qadri F, Alenina N, Bader M, Paulis L, Rajkovicova R, Domenig O, Poglitsch M, Danser AHJ.

Hypertension. 2017 Jun;69(6):1136-1144. doi: 10.1161/HYPERTENSIONAHA.116.08922. Epub 2017 Apr 10.

PMID:
28396529
7.

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.

Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ.

Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031.

8.

Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling.

van der Pluijm I, van Vliet N, von der Thusen JH, Robertus JL, Ridwan Y, van Heijningen PM, van Thiel BS, Vermeij M, Hoeks SE, Buijs-Offerman RMGB, Verhagen HJM, Kanaar R, Bertoli-Avella AM, Essers J.

EBioMedicine. 2016 Oct;12:280-294. doi: 10.1016/j.ebiom.2016.09.006. Epub 2016 Sep 10.

9.

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging.

Visser WE, Bombardieri CR, Zevenbergen C, Barnhoorn S, Ottaviani A, van der Pluijm I, Brandt R, Kaptein E, van Heerebeek R, van Toor H, Garinis GA, Peeters RP, Medici M, van Ham W, Vermeij WP, de Waard MC, de Krijger RR, Boelen A, Kwakkel J, Kopchick JJ, List EO, Melis JP, Darras VM, Dollé ME, van der Horst GT, Hoeijmakers JH, Visser TJ.

PLoS One. 2016 Mar 8;11(3):e0149941. doi: 10.1371/journal.pone.0149941. eCollection 2016.

10.

AT1-receptor blockade, but not renin inhibition, reduces aneurysm growth and cardiac failure in fibulin-4 mice.

Te Riet L, van Deel ED, van Thiel BS, Moltzer E, van Vliet N, Ridwan Y, van Veghel R, van Heijningen PM, Robertus JL, Garrelds IM, Vermeij M, van der Pluijm I, Danser AH, Essers J.

J Hypertens. 2016 Apr;34(4):654-65. doi: 10.1097/HJH.0000000000000845.

PMID:
26828783
11.

The renin-angiotensin system and its involvement in vascular disease.

van Thiel BS, van der Pluijm I, te Riet L, Essers J, Danser AH.

Eur J Pharmacol. 2015 Sep 15;763(Pt A):3-14. doi: 10.1016/j.ejphar.2015.03.090. Epub 2015 May 16. Review.

PMID:
25987425
12.

Cockayne syndrome group B (Csb) and group a (Csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.

Nagtegaal AP, Rainey RN, van der Pluijm I, Brandt RM, van der Horst GT, Borst JG, Segil N.

J Neurosci. 2015 Mar 11;35(10):4280-6. doi: 10.1523/JNEUROSCI.5063-14.2015.

13.

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.

Barnhoorn S, Uittenboogaard LM, Jaarsma D, Vermeij WP, Tresini M, Weymaere M, Menoni H, Brandt RM, de Waard MC, Botter SM, Sarker AH, Jaspers NG, van der Horst GT, Cooper PK, Hoeijmakers JH, van der Pluijm I.

PLoS Genet. 2014 Oct 9;10(10):e1004686. doi: 10.1371/journal.pgen.1004686. eCollection 2014 Oct.

14.

Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema.

Ramnath NW, van de Luijtgaarden KM, van der Pluijm I, van Nimwegen M, van Heijningen PM, Swagemakers SM, van Thiel BS, Ridwan RY, van Vliet N, Vermeij M, Hawinkels LJ, de Munck A, Dzyubachyk O, Meijering E, van der Spek P, Rottier R, Yanagisawa H, Hendriks RW, Kanaar R, Rouwet EV, Kleinjan A, Essers J.

PLoS One. 2014 Sep 25;9(9):e106054. doi: 10.1371/journal.pone.0106054. eCollection 2014.

15.

Priming of microglia in a DNA-repair deficient model of accelerated aging.

Raj DD, Jaarsma D, Holtman IR, Olah M, Ferreira FM, Schaafsma W, Brouwer N, Meijer MM, de Waard MC, van der Pluijm I, Brandt R, Kreft KL, Laman JD, de Haan G, Biber KP, Hoeijmakers JH, Eggen BJ, Boddeke HW.

Neurobiol Aging. 2014 Sep;35(9):2147-60. doi: 10.1016/j.neurobiolaging.2014.03.025. Epub 2014 Mar 28.

16.

BACH2: a marker of DNA damage and ageing.

Uittenboogaard LM, Payan-Gomez C, Pothof J, van Ijcken W, Mastroberardino PG, van der Pluijm I, Hoeijmakers JH, Tresini M.

DNA Repair (Amst). 2013 Nov;12(11):982-92. doi: 10.1016/j.dnarep.2013.08.016. Epub 2013 Sep 24.

17.

Cockayne syndrome pathogenesis: lessons from mouse models.

Jaarsma D, van der Pluijm I, van der Horst GT, Hoeijmakers JH.

Mech Ageing Dev. 2013 May-Jun;134(5-6):180-95. doi: 10.1016/j.mad.2013.04.003. Epub 2013 Apr 13. Review.

PMID:
23591128
18.

Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum.

de Graaf EL, Vermeij WP, de Waard MC, Rijksen Y, van der Pluijm I, Hoogenraad CC, Hoeijmakers JH, Altelaar AF, Heck AJ.

Mol Cell Proteomics. 2013 May;12(5):1350-62. doi: 10.1074/mcp.M112.024950. Epub 2013 Feb 11.

19.

The cross talk between pathways in the repair of 8-oxo-7,8-dihydroguanine in mouse and human cells.

Parlanti E, D'Errico M, Degan P, Calcagnile A, Zijno A, van der Pluijm I, van der Horst GT, Biard DS, Dogliotti E.

Free Radic Biol Med. 2012 Dec 1;53(11):2171-7. doi: 10.1016/j.freeradbiomed.2012.08.593. Epub 2012 Sep 7.

PMID:
23010470
20.

Nucleotide excision DNA repair is associated with age-related vascular dysfunction.

Durik M, Kavousi M, van der Pluijm I, Isaacs A, Cheng C, Verdonk K, Loot AE, Oeseburg H, Bhaggoe UM, Leijten F, van Veghel R, de Vries R, Rudez G, Brandt R, Ridwan YR, van Deel ED, de Boer M, Tempel D, Fleming I, Mitchell GF, Verwoert GC, Tarasov KV, Uitterlinden AG, Hofman A, Duckers HJ, van Duijn CM, Oostra BA, Witteman JC, Duncker DJ, Danser AH, Hoeijmakers JH, Roks AJ.

Circulation. 2012 Jul 24;126(4):468-78. doi: 10.1161/CIRCULATIONAHA.112.104380. Epub 2012 Jun 15.

21.

Synaptic proteome changes in a DNA repair deficient ercc1 mouse model of accelerated aging.

Végh MJ, de Waard MC, van der Pluijm I, Ridwan Y, Sassen MJ, van Nierop P, van der Schors RC, Li KW, Hoeijmakers JH, Smit AB, van Kesteren RE.

J Proteome Res. 2012 Mar 2;11(3):1855-67. doi: 10.1021/pr201203m. Epub 2012 Feb 13.

PMID:
22289077
22.

Accelerated loss of hearing and vision in the DNA-repair deficient Ercc1(δ/-) mouse.

Spoor M, Nagtegaal AP, Ridwan Y, Borgesius NZ, van Alphen B, van der Pluijm I, Hoeijmakers JH, Frens MA, Borst JG.

Mech Ageing Dev. 2012 Feb-Mar;133(2-3):59-67. doi: 10.1016/j.mad.2011.12.003. Epub 2012 Jan 12.

PMID:
22257940
23.

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.

Jaarsma D, van der Pluijm I, de Waard MC, Haasdijk ED, Brandt R, Vermeij M, Rijksen Y, Maas A, van Steeg H, Hoeijmakers JH, van der Horst GT.

PLoS Genet. 2011 Dec;7(12):e1002405. doi: 10.1371/journal.pgen.1002405. Epub 2011 Dec 8.

24.

Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair.

Borgesius NZ, de Waard MC, van der Pluijm I, Omrani A, Zondag GC, van der Horst GT, Melton DW, Hoeijmakers JH, Jaarsma D, Elgersma Y.

J Neurosci. 2011 Aug 31;31(35):12543-53. doi: 10.1523/JNEUROSCI.1589-11.2011.

25.

Broad segmental progeroid changes in short-lived Ercc1(-/Δ7) mice.

Dollé ME, Kuiper RV, Roodbergen M, Robinson J, de Vlugt S, Wijnhoven SW, Beems RB, de la Fonteyne L, de With P, van der Pluijm I, Niedernhofer LJ, Hasty P, Vijg J, Hoeijmakers JH, van Steeg H.

Pathobiol Aging Age Relat Dis. 2011;1. doi: 10.3402/pba.v1i0.7219. Epub 2011 Jun 1.

26.

Serum N-glycan profile shift during human ageing.

Vanhooren V, Dewaele S, Libert C, Engelborghs S, De Deyn PP, Toussaint O, Debacq-Chainiaux F, Poulain M, Glupczynski Y, Franceschi C, Jaspers K, van der Pluijm I, Hoeijmakers J, Chen CC.

Exp Gerontol. 2010 Oct;45(10):738-43. doi: 10.1016/j.exger.2010.08.009. Epub 2010 Aug 27.

PMID:
20801208
27.

CE-MS for metabolic profiling of volume-limited urine samples: application to accelerated aging TTD mice.

Nevedomskaya E, Ramautar R, Derks R, Westbroek I, Zondag G, van der Pluijm I, Deelder AM, Mayboroda OA.

J Proteome Res. 2010 Sep 3;9(9):4869-74. doi: 10.1021/pr100634d.

PMID:
20690666
28.

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.

de Waard MC, van der Pluijm I, Zuiderveen Borgesius N, Comley LH, Haasdijk ED, Rijksen Y, Ridwan Y, Zondag G, Hoeijmakers JH, Elgersma Y, Gillingwater TH, Jaarsma D.

Acta Neuropathol. 2010 Oct;120(4):461-75. doi: 10.1007/s00401-010-0715-9. Epub 2010 Jul 4.

29.

Metabolic profiling of accelerated aging ERCC1 d/- mice.

Nevedomskaya E, Meissner A, Goraler S, de Waard M, Ridwan Y, Zondag G, van der Pluijm I, Deelder AM, Mayboroda OA.

J Proteome Res. 2010 Jul 2;9(7):3680-7. doi: 10.1021/pr100210k.

PMID:
20507129
30.

Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells.

Osenbroch PØ, Auk-Emblem P, Halsne R, Strand J, Forstrøm RJ, van der Pluijm I, Eide L.

FEBS J. 2009 May;276(10):2811-21. doi: 10.1111/j.1742-4658.2009.07004.x. Epub 2009 Apr 6.

31.

Delayed and accelerated aging share common longevity assurance mechanisms.

Schumacher B, van der Pluijm I, Moorhouse MJ, Kosteas T, Robinson AR, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JH, van der Horst GT, Garinis GA.

PLoS Genet. 2008 Aug 15;4(8):e1000161. doi: 10.1371/journal.pgen.1000161.

32.

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

Mariño G, Ugalde AP, Salvador-Montoliu N, Varela I, Quirós PM, Cadiñanos J, van der Pluijm I, Freije JM, López-Otín C.

Hum Mol Genet. 2008 Jul 15;17(14):2196-211. doi: 10.1093/hmg/ddn120. Epub 2008 Apr 28.

PMID:
18443001
33.

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

van der Pluijm I, Garinis GA, Brandt RM, Gorgels TG, Wijnhoven SW, Diderich KE, de Wit J, Mitchell JR, van Oostrom C, Beems R, Niedernhofer LJ, Velasco S, Friedberg EC, Tanaka K, van Steeg H, Hoeijmakers JH, van der Horst GT.

PLoS Biol. 2007 Jan;5(1):e2. Erratum in: PLoS Biol. 2008 Nov;6(11):e304.

34.

Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome.

Gorgels TG, van der Pluijm I, Brandt RM, Garinis GA, van Steeg H, van den Aardweg G, Jansen GH, Ruijter JM, Bergen AA, van Norren D, Hoeijmakers JH, van der Horst GT.

Mol Cell Biol. 2007 Feb;27(4):1433-41. Epub 2006 Dec 4.

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