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Items: 26


Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab.

George L, Wright A, Mistry V, Sutcliffe A, Chachi L, Haldar K, Ramsheh MY, Richardson M, van der Merwe R, Martin U, Newbold P, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2019 Jun 5;14:1177-1185. doi: 10.2147/COPD.S198302. eCollection 2019.


Improving iron and zinc bioaccessibility through food-to-food fortification of pearl millet with tropical plant foodstuffs (moringa leaf powder, roselle calyces and baobab fruit pulp).

van der Merwe R, Kruger J, Ferruzzi MG, Duodu KG, Taylor JRN.

J Food Sci Technol. 2019 Apr;56(4):2244-2256. doi: 10.1007/s13197-019-03711-y. Epub 2019 Mar 20.


Tezepelumab, an anti-thymic stromal lymphopoietin monoclonal antibody, in the treatment of moderate to severe atopic dermatitis: A randomized phase 2a clinical trial.

Simpson EL, Parnes JR, She D, Crouch S, Rees W, Mo M, van der Merwe R.

J Am Acad Dermatol. 2019 Apr;80(4):1013-1021. doi: 10.1016/j.jaad.2018.11.059. Epub 2018 Dec 12.


Treatment of atopic dermatitis with tralokinumab, an anti-IL-13 mAb.

Wollenberg A, Howell MD, Guttman-Yassky E, Silverberg JI, Kell C, Ranade K, Moate R, van der Merwe R.

J Allergy Clin Immunol. 2019 Jan;143(1):135-141. doi: 10.1016/j.jaci.2018.05.029. Epub 2018 Jun 12.


Tezepelumab in Adults with Uncontrolled Asthma.

Corren J, Parnes JR, Wang L, Mo M, Roseti SL, Griffiths JM, van der Merwe R.

N Engl J Med. 2017 Sep 7;377(10):936-946. doi: 10.1056/NEJMoa1704064. Erratum in: N Engl J Med. 2019 May 23;380(21):2082.


Proteogenomic Investigation of Strain Variation in Clinical Mycobacterium tuberculosis Isolates.

Heunis T, Dippenaar A, Warren RM, van Helden PD, van der Merwe RG, Gey van Pittius NC, Pain A, Sampson SL, Tabb DL.

J Proteome Res. 2017 Oct 6;16(10):3841-3851. doi: 10.1021/acs.jproteome.7b00483. Epub 2017 Sep 11.


A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease.

Calverley PMA, Sethi S, Dawson M, Ward CK, Finch DK, Penney M, Newbold P, van der Merwe R.

Respir Res. 2017 Aug 9;18(1):153. doi: 10.1186/s12931-017-0633-7.


Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.

Aggarwal A, Parai MK, Shetty N, Wallis D, Woolhiser L, Hastings C, Dutta NK, Galaviz S, Dhakal RC, Shrestha R, Wakabayashi S, Walpole C, Matthews D, Floyd D, Scullion P, Riley J, Epemolu O, Norval S, Snavely T, Robertson GT, Rubin EJ, Ioerger TR, Sirgel FA, van der Merwe R, van Helden PD, Keller P, Böttger EC, Karakousis PC, Lenaerts AJ, Sacchettini JC.

Cell. 2017 Jul 13;170(2):249-259.e25. doi: 10.1016/j.cell.2017.06.025. Epub 2017 Jun 29.


Tralokinumab pharmacokinetics and tolerability when administered by different subcutaneous injection methods and rates

Jain M, Doughty D, Clawson C, Li X, White N, Agoram B, van der Merwe R.

Int J Clin Pharmacol Ther. 2017 Jul;55(7):606-620. doi: 10.5414/CP203023.


Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, in Patients With Moderate to Severe Crohn's Disease: A Phase 2a Study.

Sands BE, Chen J, Feagan BG, Penney M, Rees WA, Danese S, Higgins PDR, Newbold P, Faggioni R, Patra K, Li J, Klekotka P, Morehouse C, Pulkstenis E, Drappa J, van der Merwe R, Gasser RA Jr.

Gastroenterology. 2017 Jul;153(1):77-86.e6. doi: 10.1053/j.gastro.2017.03.049. Epub 2017 Apr 5.


Long-term salinity tolerance is accompanied by major restructuring of the coral bacterial microbiome.

Röthig T, Ochsenkühn MA, Roik A, van der Merwe R, Voolstra CR.

Mol Ecol. 2016 Mar;25(6):1308-23. doi: 10.1111/mec.13567. Epub 2016 Mar 1.


Whole genome sequence analysis of Mycobacterium suricattae.

Dippenaar A, Parsons SDC, Sampson SL, van der Merwe RG, Drewe JA, Abdallah AM, Siame KK, Gey van Pittius NC, van Helden PD, Pain A, Warren RM.

Tuberculosis (Edinb). 2015 Dec;95(6):682-688. doi: 10.1016/ Epub 2015 Oct 13.


Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates.

Black PA, de Vos M, Louw GE, van der Merwe RG, Dippenaar A, Streicher EM, Abdallah AM, Sampson SL, Victor TC, Dolby T, Simpson JA, van Helden PD, Warren RM, Pain A.

BMC Genomics. 2015 Oct 24;16:857. doi: 10.1186/s12864-015-2067-2.


Assessing the progress of Mycobacterium tuberculosis H37Rv structural genomics.

Fang Z, van der Merwe RG, Warren RM, Schubert WD, Gey van Pittius NC.

Tuberculosis (Edinb). 2015 Mar;95(2):131-6. doi: 10.1016/ Epub 2014 Dec 31. Review.


Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study.

Castro M, Wenzel SE, Bleecker ER, Pizzichini E, Kuna P, Busse WW, Gossage DL, Ward CK, Wu Y, Wang B, Khatry DB, van der Merwe R, Kolbeck R, Molfino NA, Raible DG.

Lancet Respir Med. 2014 Nov;2(11):879-890. doi: 10.1016/S2213-2600(14)70201-2. Epub 2014 Oct 8.


Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study.

Brightling CE, Bleecker ER, Panettieri RA Jr, Bafadhel M, She D, Ward CK, Xu X, Birrell C, van der Merwe R.

Lancet Respir Med. 2014 Nov;2(11):891-901. doi: 10.1016/S2213-2600(14)70187-0. Epub 2014 Sep 7.


Phage-based detection of bacterial pathogens.

van der Merwe RG, van Helden PD, Warren RM, Sampson SL, Gey van Pittius NC.

Analyst. 2014 Jun 7;139(11):2617-26. doi: 10.1039/c4an00208c. Review.


Challenge models to assess new therapies in chronic obstructive pulmonary disease.

van der Merwe R, Molfino NA.

Int J Chron Obstruct Pulmon Dis. 2012;7:597-605. doi: 10.2147/COPD.S30664. Epub 2012 Sep 13. Review.


Fast neural network surrogates for very high dimensional physics-based models in computational oceanography.

van der Merwe R, Leen TK, Lu Z, Frolov S, Baptista AM.

Neural Netw. 2007 May;20(4):462-78. Epub 2007 May 3. Erratum in: Neural Netw. 2007 Aug;20(6):761-2.


The bioequivalence of liquid and freeze-dried formulations of recombinant human chorionic gonadotrophin.

van der Merwe R, Lugan I, Lecuelle H, Papasouliotis O, Buraglio M.

Curr Med Res Opin. 2004 Mar;20(3):397-402.


Day clinics and hospitals--a cost comparison.

van Reenen J, van der Merwe R.

S Afr Med J. 2002 Apr;92(4):248-9; author reply 249-50. No abstract available.


Spinal cord injury as a result of endotracheal intubation in patients with undiagnosed cervical spine fractures.

Muckart DJ, Bhagwanjee S, van der Merwe R.

Anesthesiology. 1997 Aug;87(2):418-20. No abstract available.


Spontaneous drainage of an infratentorial extradural empyema: case report.

Nathoo N, Nadvi S, van der Merwe R.

Br J Neurosurg. 1997 Feb;11(1):75-7. Review.


Chronological age is a multifactorial prognostic variable in patients with non-Hodgkin's lymphoma.

Ansell SM, Falkson G, van der Merwe R, Uys A.

Ann Oncol. 1992 Jan;3(1):45-50.


Metastatic breast cancer--age has a significant effect on survival.

Alberts AS, Falkson G, van der Merwe R.

S Afr Med J. 1991 Mar 2;79(5):239-41.


Factors influencing prognosis in elderly patients with primary breast cancer.

Alberts AS, Falkson G, van der Merwe R.

S Afr J Surg. 1991 Mar;29(1):8-10.


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