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Items: 25


Organ sparing potential and inter-fraction robustness of adaptive intensity modulated proton therapy for lung cancer.

van der Laan HP, Anakotta RM, Korevaar EW, Dieters M, Ubbels JF, Wijsman R, Sijtsema NM, Both S, Langendijk JA, Muijs CT, Knopf AC.

Acta Oncol. 2019 Sep 26:1-8. doi: 10.1080/0284186X.2019.1669818. [Epub ahead of print]


Geometric Image Biomarker Changes of the Parotid Gland Are Associated With Late Xerostomia.

van Dijk LV, Brouwer CL, van der Laan HP, Burgerhof JGM, Langendijk JA, Steenbakkers RJHM, Sijtsema NM.

Int J Radiat Oncol Biol Phys. 2017 Dec 1;99(5):1101-1110. doi: 10.1016/j.ijrobp.2017.08.003. Epub 2017 Aug 12.


Radiation-induced fibrosis in the boost area after three-dimensional conformal radiotherapy with a simultaneous integrated boost technique for early-stage breast cancer: A multivariable prediction model.

Hammer C, Maduro JH, Bantema-Joppe EJ, van der Schaaf A, van der Laan HP, Langendijk JA, Crijns AP.

Radiother Oncol. 2017 Jan;122(1):45-49. doi: 10.1016/j.radonc.2016.10.006. Epub 2016 Oct 25.


Robust Intensity Modulated Proton Therapy (IMPT) Increases Estimated Clinical Benefit in Head and Neck Cancer Patients.

van Dijk LV, Steenbakkers RJ, ten Haken B, van der Laan HP, van 't Veld AA, Langendijk JA, Korevaar EW.

PLoS One. 2016 Mar 31;11(3):e0152477. doi: 10.1371/journal.pone.0152477. eCollection 2016.


Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness.

Cheng Q, Roelofs E, Ramaekers BL, Eekers D, van Soest J, Lustberg T, Hendriks T, Hoebers F, van der Laan HP, Korevaar EW, Dekker A, Langendijk JA, Lambin P.

Radiother Oncol. 2016 Feb;118(2):281-5. doi: 10.1016/j.radonc.2015.12.029. Epub 2016 Feb 26.


Swallowing sparing intensity modulated radiotherapy (SW-IMRT) in head and neck cancer: Clinical validation according to the model-based approach.

Christianen ME, van der Schaaf A, van der Laan HP, Verdonck-de Leeuw IM, Doornaert P, Chouvalova O, Steenbakkers RJ, Leemans CR, Oosting SF, van der Laan BF, Roodenburg JL, Slotman BJ, Bijl HP, Langendijk JA.

Radiother Oncol. 2016 Feb;118(2):298-303. doi: 10.1016/j.radonc.2015.11.009. Epub 2015 Dec 14.


Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer.

van Luijk P, Pringle S, Deasy JO, Moiseenko VV, Faber H, Hovan A, Baanstra M, van der Laan HP, Kierkels RG, van der Schaaf A, Witjes MJ, Schippers JM, Brandenburg S, Langendijk JA, Wu J, Coppes RP.

Sci Transl Med. 2015 Sep 16;7(305):305ra147. doi: 10.1126/scitranslmed.aac4441.


Acute symptoms during the course of head and neck radiotherapy or chemoradiation are strong predictors of late dysphagia.

van der Laan HP, Bijl HP, Steenbakkers RJ, van der Schaaf A, Chouvalova O, Vemer-van den Hoek JG, Gawryszuk A, van der Laan BF, Oosting SF, Roodenburg JL, Wopken K, Langendijk JA.

Radiother Oncol. 2015 Apr;115(1):56-62. doi: 10.1016/j.radonc.2015.01.019. Epub 2015 Mar 16.


Development of a multivariable normal tissue complication probability (NTCP) model for tube feeding dependence after curative radiotherapy/chemo-radiotherapy in head and neck cancer.

Wopken K, Bijl HP, van der Schaaf A, van der Laan HP, Chouvalova O, Steenbakkers RJ, Doornaert P, Slotman BJ, Oosting SF, Christianen ME, van der Laan BF, Roodenburg JL, Leemans CR, Verdonck-de Leeuw IM, Langendijk JA.

Radiother Oncol. 2014 Oct;113(1):95-101. doi: 10.1016/j.radonc.2014.09.013. Epub 2014 Oct 16.


Whole breast proton irradiation for maximal reduction of heart dose in breast cancer patients.

Mast ME, Vredeveld EJ, Credoe HM, van Egmond J, Heijenbrok MW, Hug EB, Kalk P, van Kempen-Harteveld LM, Korevaar EW, van der Laan HP, Langendijk JA, Rozema HJ, Petoukhova AL, Schippers JM, Struikmans H, Maduro JH.

Breast Cancer Res Treat. 2014 Nov;148(1):33-9. doi: 10.1007/s10549-014-3149-6. Epub 2014 Oct 1.


Differences in delineation guidelines for head and neck cancer result in inconsistent reported dose and corresponding NTCP.

Brouwer CL, Steenbakkers RJ, Gort E, Kamphuis ME, van der Laan HP, Van't Veld AA, Sijtsema NM, Langendijk JA.

Radiother Oncol. 2014 Apr;111(1):148-52. doi: 10.1016/j.radonc.2014.01.019. Epub 2014 Feb 20.


The impact of gastrointestinal and genitourinary toxicity on health related quality of life among irradiated prostate cancer patients.

Schaake W, Wiegman EM, de Groot M, van der Laan HP, van der Schans CP, van den Bergh AC, Langendijk JA.

Radiother Oncol. 2014 Feb;110(2):284-90. doi: 10.1016/j.radonc.2013.11.011. Epub 2014 Jan 7.


Five year outcomes of hypofractionated simultaneous integrated boost irradiation in breast conserving therapy; patterns of recurrence.

Bantema-Joppe EJ, Vredeveld EJ, de Bock GH, Busz DM, Woltman-van Iersel M, Dolsma WV, van der Laan HP, Langendijk JA, Maduro JH.

Radiother Oncol. 2013 Aug;108(2):269-72. doi: 10.1016/j.radonc.2013.08.037. Epub 2013 Sep 19.


An in silico comparison between margin-based and probabilistic target-planning approaches in head and neck cancer patients.

Fontanarosa D, van der Laan HP, Witte M, Shakirin G, Roelofs E, Langendijk JA, Lambin P, van Herk M.

Radiother Oncol. 2013 Dec;109(3):430-6. doi: 10.1016/j.radonc.2013.07.012. Epub 2013 Sep 14.


Swallowing-sparing intensity-modulated radiotherapy for head and neck cancer patients: treatment planning optimization and clinical introduction.

van der Laan HP, Gawryszuk A, Christianen ME, Steenbakkers RJ, Korevaar EW, Chouvalova O, Wopken K, Bijl HP, Langendijk JA.

Radiother Oncol. 2013 Jun;107(3):282-7. doi: 10.1016/j.radonc.2013.05.004. Epub 2013 Jun 3.


The potential of intensity-modulated proton radiotherapy to reduce swallowing dysfunction in the treatment of head and neck cancer: A planning comparative study.

van der Laan HP, van de Water TA, van Herpt HE, Christianen ME, Bijl HP, Korevaar EW, Rasch CR, van 't Veld AA, van der Schaaf A, Schilstra C, Langendijk JA; Rococo cooperative group.

Acta Oncol. 2013 Apr;52(3):561-9. doi: 10.3109/0284186X.2012.692885. Epub 2012 Jun 19.


The potential benefit of swallowing sparing intensity modulated radiotherapy to reduce swallowing dysfunction: an in silico planning comparative study.

van der Laan HP, Christianen ME, Bijl HP, Schilstra C, Langendijk JA.

Radiother Oncol. 2012 Apr;103(1):76-81. doi: 10.1016/j.radonc.2011.11.001. Epub 2011 Nov 21.


Three-dimensional conformal hypofractionated simultaneous integrated boost in breast conserving therapy: results on local control and survival.

Bantema-Joppe EJ, van der Laan HP, de Bock GH, Wijsman R, Dolsma WV, Busz DM, Langendijk JA, Maduro JH.

Radiother Oncol. 2011 Aug;100(2):215-20. doi: 10.1016/j.radonc.2011.05.027. Epub 2011 Jun 2.


Limited benefit of inversely optimised intensity modulation in breast conserving radiotherapy with simultaneously integrated boost.

van der Laan HP, Dolsma WV, Schilstra C, Korevaar EW, de Bock GH, Maduro JH, Langendijk JA.

Radiother Oncol. 2010 Mar;94(3):307-12. doi: 10.1016/j.radonc.2010.01.024. Epub 2010 Feb 18.


Current technological clinical practice in breast radiotherapy; results of a survey in EORTC-Radiation Oncology Group affiliated institutions.

van der Laan HP, Hurkmans CW, Kuten A, Westenberg HA; EORTC-ROG Breast Working Party.

Radiother Oncol. 2010 Mar;94(3):280-5. doi: 10.1016/j.radonc.2009.12.032. Epub 2010 Jan 28.


Minimising contralateral breast dose in post-mastectomy intensity-modulated radiotherapy by incorporating conformal electron irradiation.

van der Laan HP, Korevaar EW, Dolsma WV, Maduro JH, Langendijk JA.

Radiother Oncol. 2010 Feb;94(2):235-40. doi: 10.1016/j.radonc.2009.12.015. Epub 2010 Jan 18.


Dosimetric consequences of the shift towards computed tomography guided target definition and planning for breast conserving radiotherapy.

van der Laan HP, Dolsma WV, Maduro JH, Korevaar EW, Langendijk JA.

Radiat Oncol. 2008 Jan 31;3:6. doi: 10.1186/1748-717X-3-6.


Grading-system-dependent volume effects for late radiation-induced rectal toxicity after curative radiotherapy for prostate cancer.

van der Laan HP, van den Bergh A, Schilstra C, Vlasman R, Meertens H, Langendijk JA.

Int J Radiat Oncol Biol Phys. 2008 Mar 15;70(4):1138-45. Epub 2007 Oct 10.


Three-dimensional conformal simultaneously integrated boost technique for breast-conserving radiotherapy.

van der Laan HP, Dolsma WV, Maduro JH, Korevaar EW, Hollander M, Langendijk JA.

Int J Radiat Oncol Biol Phys. 2007 Jul 15;68(4):1018-23. Epub 2007 Mar 26.


Comparison of normal tissue dose with three-dimensional conformal techniques for breast cancer irradiation including the internal mammary nodes.

van der Laan HP, Dolsma WV, van 't Veld AA, Bijl HP, Langendijk JA.

Int J Radiat Oncol Biol Phys. 2005 Dec 1;63(5):1522-30. Epub 2005 Jul 5.


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