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Items: 1 to 50 of 143

1.

Clinical chronobiology: a timely consideration in critical care medicine.

McKenna H, van der Horst GTJ, Reiss I, Martin D.

Crit Care. 2018 May 11;22(1):124. doi: 10.1186/s13054-018-2041-x. Review.

2.

Differential roles for cryptochromes in the mammalian retinal clock.

Wong JCY, Smyllie NJ, Banks GT, Pothecary CA, Barnard AR, Maywood ES, Jagannath A, Hughes S, van der Horst GTJ, MacLaren RE, Hankins MW, Hastings MH, Nolan PM, Foster RG, Peirson SN.

FASEB J. 2018 Mar 21:fj201701165RR. doi: 10.1096/fj.201701165RR. [Epub ahead of print]

PMID:
29561690
3.

Early- and late-onset preeclampsia and the DNA methylation of circadian clock and clock-controlled genes in placental and newborn tissues.

van den Berg CB, Chaves I, Herzog EM, Willemsen SP, van der Horst GTJ, Steegers-Theunissen RPM.

Chronobiol Int. 2017;34(7):921-932. doi: 10.1080/07420528.2017.1326125. Epub 2017 Jun 14.

PMID:
28613964
4.

Critical cholangiocarcinogenesis control by cryptochrome clock genes.

Mteyrek A, Filipski E, Guettier C, Oklejewicz M, van der Horst GT, Okyar A, Lévi F.

Int J Cancer. 2017 Jun 1;140(11):2473-2483. doi: 10.1002/ijc.30663. Epub 2017 Mar 16.

5.

Disruption of clock gene expression in human colorectal liver metastases.

Huisman SA, Ahmadi AR, IJzermans JN, Verhoef C, van der Horst GT, de Bruin RW.

Tumour Biol. 2016 Oct;37(10):13973-13981. Epub 2016 Aug 4.

6.

Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice.

Rainey RN, Ng SY, Llamas J, van der Horst GT, Segil N.

J Neurosci. 2016 Apr 27;36(17):4758-70. doi: 10.1523/JNEUROSCI.3890-15.2016.

7.

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging.

Visser WE, Bombardieri CR, Zevenbergen C, Barnhoorn S, Ottaviani A, van der Pluijm I, Brandt R, Kaptein E, van Heerebeek R, van Toor H, Garinis GA, Peeters RP, Medici M, van Ham W, Vermeij WP, de Waard MC, de Krijger RR, Boelen A, Kwakkel J, Kopchick JJ, List EO, Melis JP, Darras VM, Dollé ME, van der Horst GT, Hoeijmakers JH, Visser TJ.

PLoS One. 2016 Mar 8;11(3):e0149941. doi: 10.1371/journal.pone.0149941. eCollection 2016.

8.

CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock.

Tamaru T, Hattori M, Honda K, Nakahata Y, Sassone-Corsi P, van der Horst GT, Ozawa T, Takamatsu K.

PLoS Biol. 2015 Nov 12;13(11):e1002293. doi: 10.1371/journal.pbio.1002293. eCollection 2015.

9.

Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis.

Hufbauer M, Cooke J, van der Horst GT, Pfister H, Storey A, Akgül B.

Mol Cancer. 2015 Oct 29;14:183. doi: 10.1186/s12943-015-0453-7.

10.

Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice.

Van Dycke KC, Rodenburg W, van Oostrom CT, van Kerkhof LW, Pennings JL, Roenneberg T, van Steeg H, van der Horst GT.

Curr Biol. 2015 Jul 20;25(14):1932-7. doi: 10.1016/j.cub.2015.06.012.

11.

Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA.

Boros G, Miko E, Muramatsu H, Weissman D, Emri E, van der Horst GT, Szegedi A, Horkay I, Emri G, Karikó K, Remenyik É.

PLoS One. 2015 Jun 29;10(6):e0131141. doi: 10.1371/journal.pone.0131141. eCollection 2015.

12.

An observational study on disturbed peripheral circadian rhythms in hemodialysis patients.

Russcher M, Chaves I, Lech K, Koch BC, Nagtegaal JE, Dorsman KF, Jong A', Kayser M, van Faassen HM, Kema IP, van der Horst GT, Gaillard CA.

Chronobiol Int. 2015;32(6):848-57. doi: 10.3109/07420528.2015.1048868. Epub 2015 Jun 23.

PMID:
26101944
13.

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

Binkhorst L, Kloth JSL, de Wit AS, de Bruijn P, Lam MH, Chaves I, Burger H, van Alphen RJ, Hamberg P, van Schaik RHN, Jager A, Koch BCP, Wiemer EAC, van Gelder T, van der Horst GTJ, Mathijssen RHJ.

Breast Cancer Res Treat. 2015 Jul;152(1):119-128. doi: 10.1007/s10549-015-3452-x. Epub 2015 Jun 7.

14.

Coupling between the Circadian Clock and Cell Cycle Oscillators: Implication for Healthy Cells and Malignant Growth.

Feillet C, van der Horst GT, Levi F, Rand DA, Delaunay F.

Front Neurol. 2015 May 11;6:96. doi: 10.3389/fneur.2015.00096. eCollection 2015. Review.

15.

Biomarkers for circadian rhythm disruption independent of time of day.

Van Dycke KC, Pennings JL, van Oostrom CT, van Kerkhof LW, van Steeg H, van der Horst GT, Rodenburg W.

PLoS One. 2015 May 18;10(5):e0127075. doi: 10.1371/journal.pone.0127075. eCollection 2015.

16.

The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK.

Schreck I, Grico N, Hansjosten I, Marquardt C, Bormann S, Seidel A, Kvietkova DL, Pieniazek D, Segerbäck D, Diabaté S, van der Horst GT, Oesch-Bartlomowicz B, Oesch F, Weiss C.

Oncogene. 2016 Feb 18;35(7):908-18. doi: 10.1038/onc.2015.145. Epub 2015 May 18.

PMID:
25982271
17.

Cockayne syndrome group B (Csb) and group a (Csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.

Nagtegaal AP, Rainey RN, van der Pluijm I, Brandt RM, van der Horst GT, Borst JG, Segil N.

J Neurosci. 2015 Mar 11;35(10):4280-6. doi: 10.1523/JNEUROSCI.5063-14.2015.

18.

Relationship Between Sunitinib Pharmacokinetics and Administration Time: Preclinical and Clinical Evidence.

Kloth JS, Binkhorst L, de Wit AS, de Bruijn P, Hamberg P, Lam MH, Burger H, Chaves I, Wiemer EA, van der Horst GT, Mathijssen RH.

Clin Pharmacokinet. 2015 Aug;54(8):851-8. doi: 10.1007/s40262-015-0239-5.

19.

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.

Barnhoorn S, Uittenboogaard LM, Jaarsma D, Vermeij WP, Tresini M, Weymaere M, Menoni H, Brandt RM, de Waard MC, Botter SM, Sarker AH, Jaspers NG, van der Horst GT, Cooper PK, Hoeijmakers JH, van der Pluijm I.

PLoS Genet. 2014 Oct 9;10(10):e1004686. doi: 10.1371/journal.pgen.1004686. eCollection 2014 Oct.

20.

Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney.

Huisman SA, Oklejewicz M, Ahmadi AR, Tamanini F, Ijzermans JN, van der Horst GT, de Bruin RW.

Int J Cancer. 2015 Mar 1;136(5):1024-32. doi: 10.1002/ijc.29089. Epub 2014 Aug 4.

21.

Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.

Feillet C, Krusche P, Tamanini F, Janssens RC, Downey MJ, Martin P, Teboul M, Saito S, Lévi FA, Bretschneider T, van der Horst GT, Delaunay F, Rand DA.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9828-33. doi: 10.1073/pnas.1320474111. Epub 2014 Jun 23.

22.

Insulin-FOXO3 signaling modulates circadian rhythms via regulation of clock transcription.

Chaves I, van der Horst GT, Schellevis R, Nijman RM, Koerkamp MG, Holstege FC, Smidt MP, Hoekman MF.

Curr Biol. 2014 Jun 2;24(11):1248-55. doi: 10.1016/j.cub.2014.04.018. Epub 2014 May 22.

23.

A day and night difference in the response of the hepatic transcriptome to cyclophosphamide treatment.

Van Dycke KC, Nijman RM, Wackers PF, Jonker MJ, Rodenburg W, van Oostrom CT, Salvatori DC, Breit TM, van Steeg H, Luijten M, van der Horst GT.

Arch Toxicol. 2015 Feb;89(2):221-31. doi: 10.1007/s00204-014-1257-z. Epub 2014 May 13.

PMID:
24819615
24.

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.

Pekovic-Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GT, Fukada Y, Meng QJ.

Genes Dev. 2014 Mar 15;28(6):548-60. doi: 10.1101/gad.237081.113.

25.

Altered phase-relationship between peripheral oscillators and environmental time in Cry1 or Cry2 deficient mouse models for early and late chronotypes.

Destici E, Jacobs EH, Tamanini F, Loos M, van der Horst GT, Oklejewicz M.

PLoS One. 2013 Dec 26;8(12):e83602. doi: 10.1371/journal.pone.0083602. eCollection 2013.

26.

Optimization of irinotecan chronotherapy with P-glycoprotein inhibition.

Filipski E, Berland E, Ozturk N, Guettier C, van der Horst GT, Lévi F, Okyar A.

Toxicol Appl Pharmacol. 2014 Feb 1;274(3):471-9. doi: 10.1016/j.taap.2013.12.018. Epub 2013 Dec 29.

PMID:
24380837
27.

Life spanning murine gene expression profiles in relation to chronological and pathological aging in multiple organs.

Jonker MJ, Melis JP, Kuiper RV, van der Hoeven TV, Wackers PFK, Robinson J, van der Horst GT, Dollé ME, Vijg J, Breit TM, Hoeijmakers JH, van Steeg H.

Aging Cell. 2013 Oct;12(5):901-909. doi: 10.1111/acel.12118. Epub 2013 Jul 14.

28.

Cockayne syndrome pathogenesis: lessons from mouse models.

Jaarsma D, van der Pluijm I, van der Horst GT, Hoeijmakers JH.

Mech Ageing Dev. 2013 May-Jun;134(5-6):180-95. doi: 10.1016/j.mad.2013.04.003. Epub 2013 Apr 13. Review.

PMID:
23591128
29.

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice.

Barclay JL, Shostak A, Leliavski A, Tsang AH, Jöhren O, Müller-Fielitz H, Landgraf D, Naujokat N, van der Horst GT, Oster H.

Am J Physiol Endocrinol Metab. 2013 May 15;304(10):E1053-63. doi: 10.1152/ajpendo.00512.2012. Epub 2013 Mar 26.

30.

Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.

Engelen E, Janssens RC, Yagita K, Smits VA, van der Horst GT, Tamanini F.

PLoS One. 2013;8(2):e56623. doi: 10.1371/journal.pone.0056623. Epub 2013 Feb 13.

31.

Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.

Valekunja UK, Edgar RS, Oklejewicz M, van der Horst GT, O'Neill JS, Tamanini F, Turner DJ, Reddy AB.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1554-9. doi: 10.1073/pnas.1214168110. Epub 2013 Jan 7.

32.

Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models.

van de Ven M, Andressoo JO, van der Horst GT, Hoeijmakers JH, Mitchell JR.

DNA Repair (Amst). 2012 Nov 1;11(11):874-83. doi: 10.1016/j.dnarep.2012.08.003. Epub 2012 Oct 7.

PMID:
23046824
33.

The cross talk between pathways in the repair of 8-oxo-7,8-dihydroguanine in mouse and human cells.

Parlanti E, D'Errico M, Degan P, Calcagnile A, Zijno A, van der Pluijm I, van der Horst GT, Biard DS, Dogliotti E.

Free Radic Biol Med. 2012 Dec 1;53(11):2171-7. doi: 10.1016/j.freeradbiomed.2012.08.593. Epub 2012 Sep 7.

PMID:
23010470
34.

Age-related skeletal dynamics and decrease in bone strength in DNA repair deficient male trichothiodystrophy mice.

Nicolaije C, Diderich KE, Botter SM, Priemel M, Waarsing JH, Day JS, Brandt RM, Schilling AF, Weinans H, Van der Eerden BC, van der Horst GT, Hoeijmakers JH, van Leeuwen JP.

PLoS One. 2012;7(4):e35246. doi: 10.1371/journal.pone.0035246. Epub 2012 Apr 10.

35.

A baculovirus photolyase with DNA repair activity and circadian clock regulatory function.

Biernat MA, Eker AP, van Oers MM, Vlak JM, van der Horst GT, Chaves I.

J Biol Rhythms. 2012 Feb;27(1):3-11. doi: 10.1177/0748730411429665.

PMID:
22306969
36.

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.

Jaarsma D, van der Pluijm I, de Waard MC, Haasdijk ED, Brandt R, Vermeij M, Rijksen Y, Maas A, van Steeg H, Hoeijmakers JH, van der Horst GT.

PLoS Genet. 2011 Dec;7(12):e1002405. doi: 10.1371/journal.pgen.1002405. Epub 2011 Dec 8.

37.

Mammalian cryptochromes impinge on cell cycle progression in a circadian clock-independent manner.

Destici E, Oklejewicz M, Saito S, van der Horst GT.

Cell Cycle. 2011 Nov 1;10(21):3788-97. doi: 10.4161/cc.10.21.17974. Epub 2011 Nov 1.

PMID:
22033214
38.

Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair.

Borgesius NZ, de Waard MC, van der Pluijm I, Omrani A, Zondag GC, van der Horst GT, Melton DW, Hoeijmakers JH, Jaarsma D, Elgersma Y.

J Neurosci. 2011 Aug 31;31(35):12543-53. doi: 10.1523/JNEUROSCI.1589-11.2011.

39.

The Potorous CPD photolyase rescues a cryptochrome-deficient mammalian circadian clock.

Chaves I, Nijman RM, Biernat MA, Bajek MI, Brand K, da Silva AC, Saito S, Yagita K, Eker AP, van der Horst GT.

PLoS One. 2011;6(8):e23447. doi: 10.1371/journal.pone.0023447. Epub 2011 Aug 16.

40.

Bone fragility and decline in stem cells in prematurely aging DNA repair deficient trichothiodystrophy mice.

Diderich KE, Nicolaije C, Priemel M, Waarsing JH, Day JS, Brandt RM, Schilling AF, Botter SM, Weinans H, van der Horst GT, Hoeijmakers JH, van Leeuwen JP.

Age (Dordr). 2012 Aug;34(4):845-61. doi: 10.1007/s11357-011-9291-8. Epub 2011 Aug 4.

41.

The cryptochromes: blue light photoreceptors in plants and animals.

Chaves I, Pokorny R, Byrdin M, Hoang N, Ritz T, Brettel K, Essen LO, van der Horst GT, Batschauer A, Ahmad M.

Annu Rev Plant Biol. 2011;62:335-64. doi: 10.1146/annurev-arplant-042110-103759. Review.

PMID:
21526969
42.

Flexible phase adjustment of circadian albumin D site-binding protein (DBP) gene expression by CRYPTOCHROME1.

Stratmann M, Stadler F, Tamanini F, van der Horst GT, Ripperger JA.

Genes Dev. 2010 Jun 15;24(12):1317-28. doi: 10.1101/gad.578810.

43.

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging.

Kamenisch Y, Fousteri M, Knoch J, von Thaler AK, Fehrenbacher B, Kato H, Becker T, Dollé ME, Kuiper R, Majora M, Schaller M, van der Horst GT, van Steeg H, Röcken M, Rapaport D, Krutmann J, Mullenders LH, Berneburg M.

J Exp Med. 2010 Feb 15;207(2):379-90. doi: 10.1084/jem.20091834. Epub 2010 Jan 25.

44.

Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.

Doi M, Takahashi Y, Komatsu R, Yamazaki F, Yamada H, Haraguchi S, Emoto N, Okuno Y, Tsujimoto G, Kanematsu A, Ogawa O, Todo T, Tsutsui K, van der Horst GT, Okamura H.

Nat Med. 2010 Jan;16(1):67-74. doi: 10.1038/nm.2061. Epub 2009 Dec 13.

PMID:
20023637
45.

Functionality of cryopreserved juvenile ovaries from mutant mice in different genetic background strains after allotransplantation.

Huang KY, de Groot SA, Woelders H, van der Horst GT, Themmen AP, Colenbrander B, van Vlissingen JM.

Cryobiology. 2010 Apr;60(2):129-37. doi: 10.1016/j.cryobiol.2009.10.003. Epub 2009 Oct 13.

PMID:
19833120
46.

Impact of the circadian clock on in vitro genotoxic risk assessment assays.

Destici E, Oklejewicz M, Nijman R, Tamanini F, van der Horst GT.

Mutat Res. 2009 Nov-Dec;680(1-2):87-94. doi: 10.1016/j.mrgentox.2009.09.001. Epub 2009 Sep 12. Review.

PMID:
19751845
47.

MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response.

Pothof J, Verkaik NS, van IJcken W, Wiemer EA, Ta VT, van der Horst GT, Jaspers NG, van Gent DC, Hoeijmakers JH, Persengiev SP.

EMBO J. 2009 Jul 22;28(14):2090-9. doi: 10.1038/emboj.2009.156. Epub 2009 Jun 18.

48.

Measurement of internal body time by blood metabolomics.

Minami Y, Kasukawa T, Kakazu Y, Iigo M, Sugimoto M, Ikeda S, Yasui A, van der Horst GT, Soga T, Ueda HR.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9890-5. doi: 10.1073/pnas.0900617106. Epub 2009 Jun 1.

49.

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B.

Nat Cell Biol. 2009 May;11(5):604-15. doi: 10.1038/ncb1866. Epub 2009 Apr 12.

50.

The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism.

Bur IM, Cohen-Solal AM, Carmignac D, Abecassis PY, Chauvet N, Martin AO, van der Horst GT, Robinson IC, Maurel P, Mollard P, Bonnefont X.

J Biol Chem. 2009 Apr 3;284(14):9066-73. doi: 10.1074/jbc.M808360200. Epub 2009 Feb 11.

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