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Items: 49

1.

Pregnancy in Advanced Kidney Disease: Clinical Practice Considerations on a Challenging Combination.

Snoek R, van der Graaf R, Meinderts JR, van Reekum F, Bloemenkamp KWM, Knoers NVAM, van Eerde AM, Lely AT.

Nephron. 2020 Feb 24:1-5. doi: 10.1159/000505781. [Epub ahead of print]

2.

Ethical issues in the design and conduct of stepped-wedge cluster randomized trials in low-resource settings.

Joag K, Ambrosio G, Kestler E, Weijer C, Hemming K, Van der Graaf R.

Trials. 2019 Dec 19;20(Suppl 2):703. doi: 10.1186/s13063-019-3842-1.

3.

Ethics of alternative trial designs and methods in low-resource settings.

van der Graaf R, Cheah PY.

Trials. 2019 Dec 19;20(Suppl 2):705. doi: 10.1186/s13063-019-3841-2.

4.

Voluntary Informed Consent Is Not Risk Dependent.

Dekking SAS, van der Graaf R, Zwaan CM, van Delden JJM.

Am J Bioeth. 2019 Apr;19(4):33-35. doi: 10.1080/15265161.2019.1572820. No abstract available.

PMID:
31544669
5.

The moral and legal status of Health Care Workers in Cluster Randomized Trials: a response to Weijer and Taljaard.

van der Graaf R, van Thiel GJMW, Hoop EO, Moons KGM, Grobbee DE, van Delden JJM.

J Clin Epidemiol. 2019 Dec;116:146-149. doi: 10.1016/j.jclinepi.2019.08.005. Epub 2019 Aug 23.

PMID:
31449856
6.

A systematic breakdown of the levels of evidence supporting the European Society of Cardiology guidelines.

van Dijk WB, Grobbee DE, de Vries MC, Groenwold RHH, van der Graaf R, Schuit E.

Eur J Prev Cardiol. 2019 Dec;26(18):1944-1952. doi: 10.1177/2047487319868540. Epub 2019 Aug 14.

7.

What constitutes a reasonable compensation for non-commercial oocyte donors: an analogy with living organ donation and medical research participation.

Kool E, van der Graaf R, Bos A, Fauser B, Bredenoord A.

J Med Ethics. 2019 Nov;45(11):736-741. doi: 10.1136/medethics-2019-105474. Epub 2019 Aug 2.

8.

Post-trial Access in Maternal Vaccine Trials.

Van Roessel IMAA, Mazur NI, Shah SK, Bont L, Van Der Graaf R.

Am J Perinatol. 2019 Jul;36(S 02):S41-S47. doi: 10.1055/s-0039-1691799. Epub 2019 Jun 25.

PMID:
31238358
9.

Views and preferences of medical professionals and pregnant women about a novel primary prevention intervention for hypertensive disorders of pregnancy: a qualitative study.

Vestering A, Bekker MN, Grobbee DE, van der Graaf R, Franx A, Crombag NMT, Browne JL.

Reprod Health. 2019 May 2;16(1):46. doi: 10.1186/s12978-019-0707-8.

10.

Stakeholders views on the ethical aspects of oocyte banking for third-party assisted reproduction: a qualitative interview study with donors, recipients and professionals.

Kool EM, van der Graaf R, Bos AME, Pieters JJPM, Custers IM, Fauser BCJM, Bredenoord AL.

Hum Reprod. 2019 May 1;34(5):842-850. doi: 10.1093/humrep/dez032.

PMID:
30927419
11.

A qualitative study on stakeholders' views on the participation of pregnant women in the APOSTEL VI study: a low-risk obstetrical RCT.

van der Zande ISE, van der Graaf R, Oudijk MA, van Vliet-Lachotzki EH, van Delden JJM.

BMC Pregnancy Childbirth. 2019 Feb 11;19(1):65. doi: 10.1186/s12884-019-2209-7.

12.

The willingness to participate in biomedical research involving human beings in low- and middle-income countries: a systematic review.

Browne JL, Rees CO, van Delden JJM, Agyepong I, Grobbee DE, Edwin A, Klipstein-Grobusch K, van der Graaf R.

Trop Med Int Health. 2019 Mar;24(3):264-279. doi: 10.1111/tmi.13195. Epub 2019 Jan 8.

13.

How the CIOMS guidelines contribute to fair inclusion of pregnant women in research.

van der Graaf R, van der Zande ISE, van Delden JJM.

Bioethics. 2019 Mar;33(3):367-373. doi: 10.1111/bioe.12520. Epub 2018 Oct 20.

14.

Protect pregnant women by including them in clinical research.

Browne J, van der Zande I, van Smeden M, van der Graaf R.

BMJ. 2018 Sep 26;362:k4013. doi: 10.1136/bmj.k4013. No abstract available.

PMID:
30257821
15.

Ethics of oocyte banking for third-party assisted reproduction: a systematic review.

Kool EM, Bos AME, van der Graaf R, Fauser BCJM, Bredenoord AL.

Hum Reprod Update. 2018 Sep 1;24(5):615-635. doi: 10.1093/humupd/dmy016.

PMID:
29762669
16.

Pediatric oncology as a Learning Health System: Ethical implications for best available treatment protocols.

van der Graaf R, Dekking SA, de Vries MC, Zwaan CM, van Delden JJM.

Learn Health Syst. 2018 Apr 16;2(2):e10052. doi: 10.1002/lrh2.10052. eCollection 2018 Apr.

17.

Good intentions do not replace ethical conduct in research.

Browne JL, Smit MR, Angira F, van der Graaf R, Bukusi EA.

Lancet. 2018 Mar 17;391(10125):1020-1021. doi: 10.1016/S0140-6736(17)32413-3. Epub 2018 Mar 15. No abstract available.

PMID:
29565011
18.

Towards an appropriate framework to facilitate responsible inclusion of pregnant women in drug development programs.

Roes KCB, van der Zande ISE, van Smeden M, van der Graaf R.

Trials. 2018 Feb 20;19(1):123. doi: 10.1186/s13063-018-2495-9.

19.

Fair inclusion of pregnant women in clinical trials: an integrated scientific and ethical approach.

van der Graaf R, van der Zande ISE, den Ruijter HM, Oudijk MA, van Delden JJM, Oude Rengerink K, Groenwold RHH.

Trials. 2018 Jan 29;19(1):78. doi: 10.1186/s13063-017-2402-9.

20.

Facilitators and barriers to pregnant women's participation in research: A systematic review.

van der Zande ISE, van der Graaf R, Hooft L, van Delden JJM.

Women Birth. 2018 Oct;31(5):350-361. doi: 10.1016/j.wombi.2017.12.009. Epub 2018 Jan 17. Review.

PMID:
29373261
21.

Ethics, regulation, and beyond: the landscape of research with pregnant women.

Saenz C, Cheah PY, van der Graaf R, Henry LM, Mastroianni AC.

Reprod Health. 2017 Dec 14;14(Suppl 3):173. doi: 10.1186/s12978-017-0421-3.

22.

Vulnerability of pregnant women in clinical research.

van der Zande ISE, van der Graaf R, Oudijk MA, van Delden JJM.

J Med Ethics. 2017 Oct;43(10):657-663. doi: 10.1136/medethics-2016-103955. Epub 2017 Jul 17. Review.

PMID:
28716977
23.

A qualitative study on acceptable levels of risk for pregnant women in clinical research.

van der Zande ISE, van der Graaf R, Oudijk MA, van Delden JJM.

BMC Med Ethics. 2017 May 15;18(1):35. doi: 10.1186/s12910-017-0194-9.

24.

The Social Value of Pragmatic Trials.

Kalkman S, van Thiel G, van der Graaf R, Zuidgeest M, Goetz I, Grobbee D, van Delden J.

Bioethics. 2017 Feb;31(2):136-143. doi: 10.1111/bioe.12315.

PMID:
28060433
25.

Revised CIOMS International Ethical Guidelines for Health-Related Research Involving Humans.

van Delden JJ, van der Graaf R.

JAMA. 2017 Jan 10;317(2):135-136. doi: 10.1001/jama.2016.18977. No abstract available.

PMID:
27923072
26.

Power Difference and Risk Perception: Mapping Vulnerability within the Decision Process of Pregnant Women towards Clinical Trial Participation in an Urban Middle-Income Setting.

Den Hollander GC, Browne JL, Arhinful D, van der Graaf R, Klipstein-Grobusch K.

Dev World Bioeth. 2018 Jun;18(2):68-75. doi: 10.1111/dewb.12132. Epub 2016 Oct 20.

27.

Brief Report: Staged-informed Consent in the Cohort Multiple Randomized Controlled Trial Design.

Young-Afat DA, Verkooijen HA, van Gils CH, van der Velden JM, Burbach JP, Elias SG, van Delden JJ, Relton C, van Vulpen M, van der Graaf R.

Epidemiology. 2016 May;27(3):389-92. doi: 10.1097/EDE.0000000000000435. Erratum in: Epidemiology. 2016 Jul;27(4):e31.

PMID:
27035689
28.

A Qualitative Study into Dependent Relationships and Voluntary Informed Consent for Research in Pediatric Oncology.

Dekking SA, van der Graaf R, Schouten-van Meeteren AY, Kars MC, van Delden JJ.

Paediatr Drugs. 2016 Apr;18(2):145-56. doi: 10.1007/s40272-015-0158-9.

29.

Voluntary Informed Consent in Paediatric Oncology Research.

Dekking SA, Van Der Graaf R, Van Delden JJ.

Bioethics. 2016 Jul;30(6):440-50. doi: 10.1111/bioe.12237. Epub 2015 Dec 21.

PMID:
26686529
30.

A systematic review of reasons for gatekeeping in palliative care research.

Kars MC, van Thiel GJ, van der Graaf R, Moors M, de Graeff A, van Delden JJ.

Palliat Med. 2016 Jun;30(6):533-48. doi: 10.1177/0269216315616759. Epub 2015 Nov 17. Review.

PMID:
26577927
31.

The need to balance merits and limitations from different disciplines when considering the stepped wedge cluster randomized trial design.

de Hoop E, van der Tweel I, van der Graaf R, Moons KG, van Delden JJ, Reitsma JB, Koffijberg H.

BMC Med Res Methodol. 2015 Oct 30;15:93. doi: 10.1186/s12874-015-0090-2.

32.

Is a New Protocol for Acute Lymphoblastic Leukemia Research or Standard Therapy?

Dekking SA, van der Graaf R, de Vries MC, Bierings MB, van Delden JJ, Kodish E, Lantos JD.

Pediatrics. 2015 Sep;136(3):566-70. doi: 10.1542/peds.2014-2327. Epub 2015 Aug 17.

33.

The ethics of cluster-randomized trials requires further evaluation: a refinement of the Ottawa Statement.

van der Graaf R, Koffijberg H, Grobbee DE, de Hoop E, Moons KG, van Thiel GJ, de Wit GA, van Delden JJ.

J Clin Epidemiol. 2015 Sep;68(9):1108-14. doi: 10.1016/j.jclinepi.2015.03.013. Epub 2015 Mar 27.

PMID:
25910909
34.

Balancing research interests and patient interests: a qualitative study into the intertwinement of care and research in paediatric oncology.

Dekking SA, van der Graaf R, Kars MC, Beishuizen A, de Vries MC, van Delden JJ.

Pediatr Blood Cancer. 2015 May;62(5):816-22. doi: 10.1002/pbc.25444. Epub 2015 Mar 1.

PMID:
25728244
35.

['Best proven care' not always the best control].

van der Graaf R, van Thiel GJ, van Delden JJ.

Ned Tijdschr Geneeskd. 2014;158:A7227; discussion A7227. Dutch.

PMID:
24690518
36.

Strengths and weaknesses of guideline approaches to safeguard voluntary informed consent of patients within a dependent relationship.

Dekking SA, van der Graaf R, van Delden JJ.

BMC Med. 2014 Mar 24;12:52. doi: 10.1186/1741-7015-12-52. Review.

37.

Justification of exclusion criteria was underreported in a review of cardiovascular trials.

Schmidt AF, Groenwold RH, van Delden JJ, van der Does Y, Klungel OH, Roes KC, Hoes AW, van der Graaf R.

J Clin Epidemiol. 2014 Jun;67(6):635-44. doi: 10.1016/j.jclinepi.2013.12.005. Epub 2014 Mar 5. Review.

38.

Issues in the use of stepped wedge cluster and alternative designs in the case of pandemics.

van der Tweel I, van der Graaf R.

Am J Bioeth. 2013;13(9):23-4. doi: 10.1080/15265161.2013.813603. No abstract available.

PMID:
23952827
39.

How and when does consent bias research?

Groenwold RH, van der Graaf R, van Delden JJ.

Am J Bioeth. 2013;13(4):46-8. doi: 10.1080/15265161.2013.767961. No abstract available.

PMID:
23514398
40.

On what we will lose in giving up on clinical equipoise: A reply to Miller.

van der Graaf R, van Delden JJ.

Clin Trials. 2012 Oct;9(5):628-9. doi: 10.1177/1740774512453221. No abstract available.

PMID:
23060320
41.

Adaptive trials in clinical research: scientific and ethical issues to consider.

van der Graaf R, Roes KC, van Delden JJ.

JAMA. 2012 Jun 13;307(22):2379-80. doi: 10.1001/jama.2012.6380. No abstract available.

PMID:
22692169
42.

Equipoise should be amended, not abandoned.

van der Graaf R, van Delden JJ.

Clin Trials. 2011 Aug;8(4):408-16. doi: 10.1177/1740774511409600. Epub 2011 Jul 11.

PMID:
21746767
43.

Toward a "post-posthuman dignity area" in evaluating emerging enhancement technologies.

Bredenoord AL, van der Graaf R, van Delden JJ.

Am J Bioeth. 2010 Jul;10(7):55-7. doi: 10.1080/15265161003686514. No abstract available.

PMID:
20582833
44.

On using people merely as a means in clinical research.

van der Graaf R, van Delden JJ.

Bioethics. 2012 Feb;26(2):76-83. doi: 10.1111/j.1467-8519.2010.01820.x. Epub 2010 Apr 5.

PMID:
20377571
45.

Conflating scientific with clinical considerations.

van der Graaf R, van Delden JJ.

Am J Bioeth. 2009 Sep;9(9):58-9. doi: 10.1080/15265160903098598. No abstract available.

PMID:
19998198
46.

Response to open peer commentaries on "What is the best standard for the standard of care in clinical research?".

van der Graaf R, van Delden JJ.

Am J Bioeth. 2009;9(6-7):W7-8. doi: 10.1080/15265160902918804. No abstract available.

PMID:
19998101
47.

What is the best standard for the standard of care in clinical research?

van der Graaf R, van Delden JJ.

Am J Bioeth. 2009 Mar;9(3):35-43. doi: 10.1080/15265160802654129.

PMID:
19247887
48.

Clarifying appeals to dignity in medical ethics from an historical perspective.

Van Der Graaf R, Van Delden JJ.

Bioethics. 2009 Mar;23(3):151-60. doi: 10.1111/j.1467-8519.2008.00646.x.

PMID:
19161568
49.

Expression in Escherichia coli and purification of a translocation-competent precursor of the chloroplast protein ferredoxin.

Pilon M, de Boer AD, Knols SL, Koppelman MH, van der Graaf RM, de Kruijff B, Weisbeek PJ.

J Biol Chem. 1990 Feb 25;265(6):3358-61.

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