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Items: 19

1.

Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes.

van der Geld YM, Hellmark T, Selga D, Heeringa P, Huitema MG, Limburg PC, Kallenberg CG.

Ann Rheum Dis. 2007 Dec;66(12):1679-82. Epub 2007 Jul 20.

2.

Functional defect of circulating regulatory CD4+ T cells in patients with Wegener's granulomatosis in remission.

Abdulahad WH, Stegeman CA, van der Geld YM, Doornbos-van der Meer B, Limburg PC, Kallenberg CG.

Arthritis Rheum. 2007 Jun;56(6):2080-91.

3.

Different modulation of decorin production by lung fibroblasts from patients with mild and severe emphysema.

Noordhoek JA, Postma DS, Chong LL, Menkema L, Kauffman HF, Timens W, van Straaten JF, van der Geld YM.

COPD. 2005 Mar;2(1):17-25.

PMID:
17136957
4.

Persistent expansion of CD4+ effector memory T cells in Wegener's granulomatosis.

Abdulahad WH, van der Geld YM, Stegeman CA, Kallenberg CG.

Kidney Int. 2006 Sep;70(5):938-47. Epub 2006 Jul 12.

5.

Altered expression of the Smad signalling pathway: implications for COPD pathogenesis.

Zandvoort A, Postma DS, Jonker MR, Noordhoek JA, Vos JT, van der Geld YM, Timens W.

Eur Respir J. 2006 Sep;28(3):533-41. Epub 2006 May 17.

6.

High ICAM-1 gene expression in pulmonary fibroblasts of COPD patients: a reflection of an enhanced immunological function.

Zandvoort A, van der Geld YM, Jonker MR, Noordhoek JA, Vos JT, Wesseling J, Kauffman HF, Timens W, Postma DS.

Eur Respir J. 2006 Jul;28(1):113-22. Epub 2006 Apr 12.

7.

Human anti-neutrophil cytoplasm autoantibodies to proteinase 3 (PR3-ANCA) bind to neutrophils.

Van Rossum AP, van der Geld YM, Limburg PC, Kallenberg CG.

Kidney Int. 2005 Aug;68(2):537-41.

8.

B cell epitope specificity in ANCA-associated vasculitis: does it matter?

van der Geld YM, Stegeman CA, Kallenberg CG.

Clin Exp Immunol. 2004 Sep;137(3):451-9. Review.

9.

Diversity of PR3-ANCA epitope specificity in Wegener's granulomatosis. Analysis using the biosensor technology.

Rarok AA, van der Geld YM, Stegeman CA, Limburg PC, Kallenberg CG.

J Clin Immunol. 2003 Nov;23(6):460-8.

PMID:
15031633
10.

Recombinant protein to analyze autoantibodies to proteinase 3 in systemic vasculitis.

Rarok AA, Huitema MG, van der Leij MJ, van der Geld YM, Berthold H, Schmitt J, Stegeman CA, Limburg PC, Kallenberg CG.

Am J Clin Pathol. 2003 Oct;120(4):586-95.

PMID:
14560570
11.

Interference of PR3-ANCA with the enzymatic activity of PR3: differences in patients during active disease or remission of Wegener's granulomatosis.

van der Geld YM, Tool AT, Videler J, de Haas M, Tervaert JW, Stegeman CA, Limburg PC, Kallenberg CG, Roos D.

Clin Exp Immunol. 2002 Sep;129(3):562-70.

12.

Expression of recombinant proteinase 3, the autoantigen in Wegener's granulomatosis, in insect cells.

Van der Geld YM, Smook ML, Huitema MG, Harmsen MC, Limburg PC, Kallenberg CG.

J Immunol Methods. 2002 Jun 1;264(1-2):195-205.

PMID:
12191522
13.

Proteinase 3, Wegener's autoantigen: from gene to antigen.

van der Geld YM, Limburg PC, Kallenberg CG.

J Leukoc Biol. 2001 Feb;69(2):177-90. Review.

PMID:
11272267
14.

Antineutrophil cytoplasmic antibodies to proteinase 3 in Wegener's granulomatosis: epitope analysis using synthetic peptides.

Van Der Geld YM, Simpelaar A, Van Der Zee R, Tervaert JW, Stegeman CA, Limburg PC, Kallenberg CG.

Kidney Int. 2001 Jan;59(1):147-59.

15.

In vitro T lymphocyte responses to proteinase 3 (PR3) and linear peptides of PR3 in patients with Wegener's granulomatosis (WG).

van der Geld YM, Huitema MG, Franssen CF, van der Zee R, Limburg PC, Kallenberg CG.

Clin Exp Immunol. 2000 Dec;122(3):504-13.

16.

Recombinant proteinase 3 produced in different expression systems: recognition by anti-PR3 antibodies.

van der Geld YM, Oost-Kort W, Limburg PC, Specks U, Kallenberg CG.

J Immunol Methods. 2000 Oct 20;244(1-2):117-31.

PMID:
11033024
17.
18.

Pathophysiology of ANCA-associated glomerulonephritis.

Muller Kobold AC, van der Geld YM, Limburg PC, Tervaert JW, Kallenberg CG.

Nephrol Dial Transplant. 1999 Jun;14(6):1366-75. Review. No abstract available.

PMID:
10382995
19.

Recombinant proteinase 3 (Wegener's antigen) expressed in Pichia pastoris is functionally active and is recognized by patient sera.

Harmsen MC, Heeringa P, van der Geld YM, Huitema MG, Klimp A, Tiran A, Kallenberg CG.

Clin Exp Immunol. 1997 Nov;110(2):257-64.

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