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Items: 1 to 50 of 57

1.

Identification of STS-1 as a novel ShcA-binding protein.

van der Meulen T, Swarts S, Fischer W, van der Geer P.

Biochem Biophys Res Commun. 2017 Sep 2;490(4):1334-1339. doi: 10.1016/j.bbrc.2017.07.024. Epub 2017 Jul 6.

PMID:
28690151
2.

Identification and mutagenesis of the TACE and γ-secretase cleavage sites in the colony-stimulating factor 1 receptor.

Vahidi A, Glenn G, van der Geer P.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):782-7. doi: 10.1016/j.bbrc.2014.06.061. Epub 2014 Jun 21.

PMID:
24955855
3.

Analysis of protein-protein interactions by coimmunoprecipitation.

van der Geer P.

Methods Enzymol. 2014;541:35-47. doi: 10.1016/B978-0-12-420119-4.00004-5.

PMID:
24674061
4.

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis.

Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy AN.

EMBO Mol Med. 2013 Jun;5(6):904-18. doi: 10.1002/emmm.201201429. Epub 2013 May 24.

5.

Protein instability following transport or storage on dry ice.

Murphy BM, Swarts S, Mueller BM, van der Geer P, Manning MC, Fitchmun MI.

Nat Methods. 2013 Apr;10(4):278-9. doi: 10.1038/nmeth.2409. No abstract available.

PMID:
23538862
6.

Engineering NGF receptors to bind Grb2 directly uncovers differences in signaling ability between Grb2- and ShcA-binding sites.

Oku S, van der Meulen T, Copp J, Glenn G, van der Geer P.

FEBS Lett. 2012 Oct 19;586(20):3658-64. doi: 10.1016/j.febslet.2012.08.021. Epub 2012 Aug 30.

7.

Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

Beaujouin M, Prébois C, Derocq D, Laurent-Matha V, Masson O, Pattingre S, Coopman P, Bettache N, Grossfield J, Hollingsworth RE, Zhang H, Yao Z, Hyman BT, van der Geer P, Smith GK, Liaudet-Coopman E.

J Cell Sci. 2010 Oct 1;123(Pt 19):3336-46. doi: 10.1242/jcs.070938. Epub 2010 Sep 7.

8.

Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1.

Guttman M, Betts GN, Barnes H, Ghassemian M, van der Geer P, Komives EA.

Proteomics. 2009 Nov;9(22):5016-28. doi: 10.1002/pmic.200900457.

9.

Phosphopeptide mapping and identification of phosphorylation sites.

Meisenhelder J, Hunter T, van der Geer P.

Curr Protoc Protein Sci. 2001 May;Chapter 13:Unit13.9. doi: 10.1002/0471140864.ps1309s18.

PMID:
18429120
10.

Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain.

Betts GN, van der Geer P, Komives EA.

J Biol Chem. 2008 Jun 6;283(23):15656-64. doi: 10.1074/jbc.M709514200. Epub 2008 Apr 1.

11.

Toll-like receptors stimulate regulated intramembrane proteolysis of the CSF-1 receptor through Erk activation.

Glenn G, van der Geer P.

FEBS Lett. 2008 Mar 19;582(6):911-5. doi: 10.1016/j.febslet.2008.02.029. Epub 2008 Feb 21.

12.

Phosphopeptide mapping and identification of phosphorylation sites.

Meisenhelder J, Hunter T, van der Geer P.

Curr Protoc Mol Biol. 2001 May;Chapter 18:Unit 18.9. doi: 10.1002/0471142727.mb1809s48.

PMID:
18265174
13.
14.

The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster.

Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy AN, Jennings PA, Dixon JE.

J Biol Chem. 2007 Aug 17;282(33):23745-9. Epub 2007 Jun 21.

15.

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.

Wiley SE, Murphy AN, Ross SA, van der Geer P, Dixon JE.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5318-23. Epub 2007 Mar 21.

16.

Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium.

MacFadyen JR, Haworth O, Roberston D, Hardie D, Webster MT, Morris HR, Panico M, Sutton-Smith M, Dell A, van der Geer P, Wienke D, Buckley CD, Isacke CM.

FEBS Lett. 2005 May 9;579(12):2569-75. Epub 2005 Apr 7.

17.

Hypertonic shock inhibits growth factor receptor signaling, induces caspase-3 activation, and causes reversible fragmentation of the mitochondrial network.

Copp J, Wiley S, Ward MW, van der Geer P.

Am J Physiol Cell Physiol. 2005 Feb;288(2):C403-15. Epub 2004 Sep 29.

18.

Purification and identification of protein-tyrosine kinase-binding proteins using synthetic phosphopeptides as affinity reagents.

Wilhelmsen K, Copp J, Glenn G, Hoffman RC, Tucker P, van der Geer P.

Mol Cell Proteomics. 2004 Sep;3(9):887-95. Epub 2004 Jun 23.

19.

GW domains of the Listeria monocytogenes invasion protein InlB are required for potentiation of Met activation.

Banerjee M, Copp J, Vuga D, Marino M, Chapman T, van der Geer P, Ghosh P.

Mol Microbiol. 2004 Apr;52(1):257-71.

20.

Characterization of the calcium-binding sites of Listeria monocytogenes InlB.

Marino M, Banerjee M, Copp J, Dramsi S, Chapman T, van der Geer P, Cossart P, Ghosh P.

Biochem Biophys Res Commun. 2004 Apr 2;316(2):379-86.

PMID:
15020228
22.

v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.

Barnes H, Ackermann EJ, van der Geer P.

Oncogene. 2003 Jun 5;22(23):3589-97.

PMID:
12789267
23.

Multiple regions of internalin B contribute to its ability to turn on the Ras-mitogen-activated protein kinase pathway.

Copp J, Marino M, Banerjee M, Ghosh P, van der Geer P.

J Biol Chem. 2003 Mar 7;278(10):7783-9. Epub 2002 Dec 17.

24.

Phosphorylation of LRP1: regulation of transport and signal transduction.

van der Geer P.

Trends Cardiovasc Med. 2002 May;12(4):160-5. Review.

PMID:
12069755
25.

C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.

Wilhelmsen K, Burkhalter S, van der Geer P.

Oncogene. 2002 Feb 7;21(7):1079-89.

26.

RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization.

Tourrière H, Gallouzi IE, Chebli K, Capony JP, Mouaikel J, van der Geer P, Tazi J.

Mol Cell Biol. 2001 Nov;21(22):7747-60.

27.

Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC-transformed cells.

Barnes H, Larsen B, Tyers M, van Der Geer P.

J Biol Chem. 2001 Jun 1;276(22):19119-25. Epub 2001 Mar 20.

28.

The shc adaptor protein forms interdependent phosphotyrosine-mediated protein complexes in mast cells stimulated with interleukin 3.

Velazquez L, Gish GD, van Der Geer P, Taylor L, Shulman J, Pawson T.

Blood. 2000 Jul 1;96(1):132-8.

PMID:
10891441
29.

Role of p120 Ras-GAP in directed cell movement.

Kulkarni SV, Gish G, van der Geer P, Henkemeyer M, Pawson T.

J Cell Biol. 2000 Apr 17;149(2):457-70.

30.
31.

Tyrosine phosphorylation of shc in response to B cell antigen receptor engagement depends on the SHIP inositol phosphatase.

Ingham RJ, Okada H, Dang-Lawson M, Dinglasan J, van Der Geer P, Kurosaki T, Gold MR.

J Immunol. 1999 Dec 1;163(11):5891-5.

32.
33.

Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.

van der Geer P, Henkemeyer M, Jacks T, Pawson T.

Mol Cell Biol. 1997 Apr;17(4):1840-7.

34.

Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.

Li SC, Lai KM, Gish GD, Parris WE, van der Geer P, Forman-Kay J, Pawson T.

J Biol Chem. 1996 Dec 13;271(50):31855-62.

35.

Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1.

Piao X, Paulson R, van der Geer P, Pawson T, Bernstein A.

Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14665-9.

36.
37.

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

van der Geer P, Wiley S, Gish GD, Lai VK, Stephens R, White MF, Kaplan D, Pawson T.

Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):963-8.

38.

MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1-Shc and mSos1-EGF receptor complexes.

Rozakis-Adcock M, van der Geer P, Mbamalu G, Pawson T.

Oncogene. 1995 Oct 5;11(7):1417-26.

PMID:
7478566
39.

The PTB domain: a new protein module implicated in signal transduction.

van der Geer P, Pawson T.

Trends Biochem Sci. 1995 Jul;20(7):277-80. Review.

PMID:
7545337
41.

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.

van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.

Curr Biol. 1995 Apr 1;5(4):404-12.

42.

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.

Schlaepfer DD, Hanks SK, Hunter T, van der Geer P.

Nature. 1994 Dec 22-29;372(6508):786-91.

PMID:
7997267
43.

Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elements.

Trautwein C, van der Geer P, Karin M, Hunter T, Chojkier M.

J Clin Invest. 1994 Jun;93(6):2554-61.

44.
45.

Receptor protein-tyrosine kinases and their signal transduction pathways.

van der Geer P, Hunter T, Lindberg RA.

Annu Rev Cell Biol. 1994;10:251-337. Review. No abstract available.

PMID:
7888178
47.

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain.

Trautwein C, Caelles C, van der Geer P, Hunter T, Karin M, Chojkier M.

Nature. 1993 Aug 5;364(6437):544-7.

PMID:
8336793
48.

Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions.

Reedijk M, Liu X, van der Geer P, Letwin K, Waterfield MD, Hunter T, Pawson T.

EMBO J. 1992 Apr;11(4):1365-72.

49.

Receptor protein tyrosine kinases and phosphatases.

Hunter T, Lindberg RA, Middlemas DS, Tracy S, van der Geer P.

Cold Spring Harb Symp Quant Biol. 1992;57:25-41. Review.

PMID:
1339664

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