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Items: 46

1.

Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT).

Zwartsen A, Litjens CHC, Hondebrink L, van den Heuvel JJMW, Greupink R, Russel FGM, de Lange DW, Legler J, Koenderink JB, Westerink RHS.

Toxicology. 2019 Jun 15;422:69-75. doi: 10.1016/j.tox.2019.04.012. Epub 2019 Apr 19.

2.

Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity.

Weigand KM, Schirris TJJ, Houweling M, van den Heuvel JJMW, Koenderink JB, Dankers ACA, Russel FGM, Greupink R.

Toxicol In Vitro. 2019 Apr;56:52-61. doi: 10.1016/j.tiv.2019.01.003. Epub 2019 Jan 9.

3.

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.

van der Velden M, Bilos A, van den Heuvel JJMW, Rijpma SR, Hurkmans EGE, Sauerwein RW, Russel FGM, Koenderink JB.

Malar J. 2017 Oct 23;16(1):422. doi: 10.1186/s12936-017-2062-y.

4.

Editor's Highlight: PlacentalDisposition and Effects of Crizotinib: An Ex Vivo Study in the Isolated Dual-Side Perfused Human Cotyledon.

Eliesen GAM, van den Broek P, van den Heuvel JJ, Bilos A, Pertijs J, van Drongelen J, Russel FGM, Greupink R.

Toxicol Sci. 2017 Jun 1;157(2):500-509. doi: 10.1093/toxsci/kfx063.

PMID:
28369651
5.

Transmembrane Domain Single-Nucleotide Polymorphisms Impair Expression and Transport Activity of ABC Transporter ABCG2.

Sjöstedt N, van den Heuvel JJMW, Koenderink JB, Kidron H.

Pharm Res. 2017 Aug;34(8):1626-1636. doi: 10.1007/s11095-017-2127-1. Epub 2017 Mar 9.

6.

Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.

Te Brake LH, van den Heuvel JJ, Buaben AO, van Crevel R, Bilos A, Russel FG, Aarnoutse RE, Koenderink JB.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7105-7114. Print 2016 Dec.

7.

Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP.

Lempers VJ, van den Heuvel JJ, Russel FG, Aarnoutse RE, Burger DM, Brüggemann RJ, Koenderink JB.

Antimicrob Agents Chemother. 2016 May 23;60(6):3372-9. doi: 10.1128/AAC.02931-15. Print 2016 Jun.

8.

Inhibitory potential of tuberculosis drugs on ATP-binding cassette drug transporters.

Te Brake LH, Russel FG, van den Heuvel JJ, de Knegt GJ, de Steenwinkel JE, Burger DM, Aarnoutse RE, Koenderink JB.

Tuberculosis (Edinb). 2016 Jan;96:150-7. doi: 10.1016/j.tube.2015.08.004. Epub 2015 Oct 9.

PMID:
26682943
9.

Feline hepatic biotransformation of diazepam: Differences between cats and dogs.

van Beusekom CD, van den Heuvel JJ, Koenderink JB, Russel FG, Schrickx JA.

Res Vet Sci. 2015 Dec;103:119-25. doi: 10.1016/j.rvsc.2015.09.016. Epub 2015 Sep 25.

PMID:
26679806
10.

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites.

Rijpma SR, van der Velden M, González-Pons M, Annoura T, van Schaijk BC, van Gemert GJ, van den Heuvel JJ, Ramesar J, Chevalley-Maurel S, Ploemen IH, Khan SM, Franetich JF, Mazier D, de Wilt JH, Serrano AE, Russel FG, Janse CJ, Sauerwein RW, Koenderink JB, Franke-Fayard BM.

Cell Microbiol. 2016 Mar;18(3):369-83. doi: 10.1111/cmi.12517. Epub 2015 Nov 10.

11.

Convallatoxin: a new P-glycoprotein substrate.

Gozalpour E, Greupink R, Bilos A, Verweij V, van den Heuvel JJ, Masereeuw R, Russel FG, Koenderink JB.

Eur J Pharmacol. 2014 Dec 5;744:18-27. doi: 10.1016/j.ejphar.2014.09.031. Epub 2014 Sep 28.

PMID:
25264938
12.

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity.

Rijpma SR, van den Heuvel JJ, van der Velden M, Sauerwein RW, Russel FG, Koenderink JB.

Malar J. 2014 Sep 13;13:359. doi: 10.1186/1475-2875-13-359.

13.

cCMP is a substrate for MRP5.

Laue S, Winterhoff M, Kaever V, van den Heuvel JJ, Russel FG, Seifert R.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Sep;387(9):893-5. doi: 10.1007/s00210-014-1018-9. Epub 2014 Jul 15.

PMID:
25017019
14.

In silico identification and in vitro validation of potential cholestatic compounds through 3D ligand-based pharmacophore modeling of BSEP inhibitors.

Ritschel T, Hermans SM, Schreurs M, van den Heuvel JJ, Koenderink JB, Greupink R, Russel FG.

Chem Res Toxicol. 2014 May 19;27(5):873-81. doi: 10.1021/tx5000393. Epub 2014 Apr 23.

PMID:
24713091
15.

The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEP.

van Beusekom CD, van den Heuvel JJ, Koenderink JB, Schrickx JA, Russel FG.

BMC Vet Res. 2013 Dec 20;9:259. doi: 10.1186/1746-6148-9-259.

16.

Glutathione status and the renal elimination of inorganic mercury in the Mrp2(-/-) mouse.

Bridges CC, Joshee L, van den Heuvel JJ, Russel FG, Zalups RK.

PLoS One. 2013 Sep 5;8(9):e73559. doi: 10.1371/journal.pone.0073559. eCollection 2013.

17.

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4.

El-Sheikh AA, Greupink R, Wortelboer HM, van den Heuvel JJ, Schreurs M, Koenderink JB, Masereeuw R, Russel FG.

Transl Res. 2013 Dec;162(6):398-409. doi: 10.1016/j.trsl.2013.08.003. Epub 2013 Sep 12.

PMID:
24036158
18.

Interaction of digitalis-like compounds with p-glycoprotein.

Gozalpour E, Wittgen HG, van den Heuvel JJ, Greupink R, Russel FG, Koenderink JB.

Toxicol Sci. 2013 Feb;131(2):502-11. doi: 10.1093/toxsci/kfs307. Epub 2012 Oct 26.

PMID:
23104431
19.

Heme Oxygenase-1 and breast cancer resistance protein protect against heme-induced toxicity.

Wagener FA, Dankers AC, van Summeren F, Scharstuhl A, van den Heuvel JJ, Koenderink JB, Pennings SW, Russel FG, Masereeuw R.

Curr Pharm Des. 2013;19(15):2698-707.

PMID:
23092328
20.

Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones.

Dankers AC, Sweep FC, Pertijs JC, Verweij V, van den Heuvel JJ, Koenderink JB, Russel FG, Masereeuw R.

Cell Tissue Res. 2012 Aug;349(2):551-63. doi: 10.1007/s00441-012-1417-5. Epub 2012 May 13.

21.

Phenylalanine 368 of multidrug resistance-associated protein 4 (MRP4/ABCC4) plays a crucial role in substrate-specific transport activity.

Wittgen HG, van den Heuvel JJ, Krieger E, Schaftenaar G, Russel FG, Koenderink JB.

Biochem Pharmacol. 2012 Aug 1;84(3):366-73. doi: 10.1016/j.bcp.2012.04.012. Epub 2012 Apr 21.

PMID:
22542979
22.

Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

Wittgen HG, Greupink R, van den Heuvel JJ, van den Broek PH, Dinter-Heidorn H, Koenderink JB, Russel FG.

Mol Pharm. 2012 May 7;9(5):1351-60. doi: 10.1021/mp200617z. Epub 2012 Mar 28.

PMID:
22428727
23.

Transport of the coumarin metabolite 7-hydroxycoumarin glucuronide is mediated via multidrug resistance-associated proteins 3 and 4.

Wittgen HG, van den Heuvel JJ, van den Broek PH, Siissalo S, Groothuis GM, de Graaf IA, Koenderink JB, Russel FG.

Drug Metab Dispos. 2012 Jun;40(6):1076-9. doi: 10.1124/dmd.111.044438. Epub 2012 Mar 12.

PMID:
22415933
24.

Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4.

Wittgen HG, van den Heuvel JJ, van den Broek PH, Dinter-Heidorn H, Koenderink JB, Russel FG.

Drug Metab Dispos. 2011 Jul;39(7):1294-302. doi: 10.1124/dmd.110.037812. Epub 2011 Apr 21.

PMID:
21511945
25.

Chemotherapy-induced nausea and vomiting in daily clinical practice: a community hospital-based study.

Hilarius DL, Kloeg PH, van der Wall E, van den Heuvel JJ, Gundy CM, Aaronson NK.

Support Care Cancer. 2012 Jan;20(1):107-17. doi: 10.1007/s00520-010-1073-9. Epub 2011 Jan 22.

26.

[Substitution of dexamethasone for dexamphetamine due to their written and spoken similarity].

Hoppenbrouwers CJ, Mooren GC, van den Heuvel JJ, Op de Coul ME, van Trotsenburg PA.

Ned Tijdschr Geneeskd. 2010;154:A1662. Dutch.

PMID:
20858310
27.

Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation.

de Vries B, Stam AH, Kirkpatrick M, Vanmolkot KR, Koenderink JB, van den Heuvel JJ, Stunnenberg B, Goudie D, Shetty J, Jain V, van Vark J, Terwindt GM, Frants RR, Haan J, van den Maagdenberg AM, Ferrari MD.

Epilepsia. 2009 Nov;50(11):2503-4. doi: 10.1111/j.1528-1167.2009.02186.x. No abstract available.

28.

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4.

El-Sheikh AA, van den Heuvel JJ, Koenderink JB, Russel FG.

Br J Pharmacol. 2008 Dec;155(7):1066-75. doi: 10.1038/bjp.2008.343. Epub 2008 Aug 25.

29.

Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4).

El-Sheikh AA, van den Heuvel JJ, Krieger E, Russel FG, Koenderink JB.

Mol Pharmacol. 2008 Oct;74(4):964-71. doi: 10.1124/mol.107.043661. Epub 2008 Jul 8.

PMID:
18612080
30.

Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine.

de Vries B, Freilinger T, Vanmolkot KR, Koenderink JB, Stam AH, Terwindt GM, Babini E, van den Boogerd EH, van den Heuvel JJ, Frants RR, Haan J, Pusch M, van den Maagdenberg AM, Ferrari MD, Dichgans M.

Neurology. 2007 Dec 4;69(23):2170-6.

PMID:
18056581
31.

Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes.

Castro MJ, Nunes B, de Vries B, Lemos C, Vanmolkot KR, van den Heuvel JJ, Temudo T, Barros J, Sequeiros J, Frants RR, Koenderink JB, Pereira-Monteiro JM, van den Maagdenberg AM.

Clin Genet. 2008 Jan;73(1):37-43. Epub 2007 Nov 19.

PMID:
18028456
32.

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane.

Huls M, Brown CD, Windass AS, Sayer R, van den Heuvel JJ, Heemskerk S, Russel FG, Masereeuw R.

Kidney Int. 2008 Jan;73(2):220-5. Epub 2007 Oct 31.

33.

Transport of a fluorescent cAMP analog in teleost proximal tubules.

Reichel V, Masereeuw R, van den Heuvel JJ, Miller DS, Fricker G.

Am J Physiol Regul Integr Comp Physiol. 2007 Dec;293(6):R2382-9. Epub 2007 Sep 12.

34.

First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine.

Vanmolkot KR, Stam AH, Raman A, Koenderink JB, de Vries B, van den Boogerd EH, van Vark J, van den Heuvel JJ, Bajaj N, Terwindt GM, Haan J, Frants RR, Ferrari MD, van den Maagdenberg AM.

Eur J Hum Genet. 2007 Aug;15(8):884-8. Epub 2007 May 2.

35.

Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport.

El-Sheikh AA, van den Heuvel JJ, Koenderink JB, Russel FG.

J Pharmacol Exp Ther. 2007 Jan;320(1):229-35. Epub 2006 Sep 27.

PMID:
17005917
36.

ABC transporter expression profiling after ischemic reperfusion injury in mouse kidney.

Huls M, van den Heuvel JJ, Dijkman HB, Russel FG, Masereeuw R.

Kidney Int. 2006 Jun;69(12):2186-93. Epub 2006 Apr 12.

37.

Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine.

Vanmolkot KR, Kors EE, Turk U, Turkdogan D, Keyser A, Broos LA, Kia SK, van den Heuvel JJ, Black DF, Haan J, Frants RR, Barone V, Ferrari MD, Casari G, Koenderink JB, van den Maagdenberg AM.

Eur J Hum Genet. 2006 May;14(5):555-60.

38.

Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation.

Vanmolkot KR, Stroink H, Koenderink JB, Kors EE, van den Heuvel JJ, van den Boogerd EH, Stam AH, Haan J, De Vries BB, Terwindt GM, Frants RR, Ferrari MD, van den Maagdenberg AM.

Ann Neurol. 2006 Feb;59(2):310-4.

PMID:
16437583
39.
40.

Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.

Van Aubel RA, Smeets PH, van den Heuvel JJ, Russel FG.

Am J Physiol Renal Physiol. 2005 Feb;288(2):F327-33. Epub 2004 Sep 28.

41.

Placental folate transport and binding are not impaired in pregnancies complicated by fetal growth restriction.

Bisseling TM, Steegers EA, van den Heuvel JJ, Siero HL, van de Water FM, Walker AJ, Steegers-Theunissen RP, Smits P, Russel FG.

Placenta. 2004 Jul;25(6):588-93.

PMID:
15135243
43.

Effects of phosphoglycerate kinase overproduction in Saccharomyces cerevisiae on the physiology and plasmid stability.

van der Aar PC, van den Heuvel JJ, Röling WF, Raué HA, Stouthamer AH, van Verseveld HW.

Yeast. 1992 Jan;8(1):47-55.

PMID:
1580100
44.

Effect of leader primary structure on the translational efficiency of phosphoglycerate kinase mRNA in yeast.

van den Heuvel JJ, Planta RJ, Raué HA.

Yeast. 1990 Nov-Dec;6(6):473-82.

PMID:
2080664
45.

Effect of deletions in the 5'-noncoding region on the translational efficiency of phosphoglycerate kinase mRNA in yeast.

van den Heuvel JJ, Bergkamp RJ, Planta RJ, Raué HA.

Gene. 1989 Jun 30;79(1):83-95.

PMID:
2673936
46.

Correct removal by splicing of a Neurospora intron in yeast.

Woudt LP, van den Heuvel JJ, van Raamsdonk-Duin MM, Mager WH, Planta RJ.

Nucleic Acids Res. 1985 Nov 11;13(21):7729-39.

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