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Items: 1 to 50 of 199

1.

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics.

Eijkelenboom A, Tops BBJ, van den Berg A, van den Brule AJC, Dinjens WNM, Dubbink HJ, Ter Elst A, Geurts-Giele WRR, Groenen PJTA, Groenendijk FH, Heideman DAM, Huibers MMH, Huijsmans CJJ, Jeuken JWM, van Kempen LC, Korpershoek E, Kroeze LI, de Leng WWJ, van Noesel CJM, Speel EM, Vogel MJ, van Wezel T, Nederlof PM, Schuuring E, Ligtenberg MJL.

Virchows Arch. 2019 Jun;474(6):673-680. doi: 10.1007/s00428-019-02555-3. Epub 2019 Mar 19.

2.

Soluble mannose receptor levels in blood correlate to disease severity in patients with community-acquired pneumonia.

Loonen AJM, Leijtens S, Serin O, Hilbink M, Wever PC, van den Brule AJC, Toonen EJM.

Immunol Lett. 2019 Feb;206:28-32. doi: 10.1016/j.imlet.2018.12.001. Epub 2018 Dec 4.

PMID:
30521839
3.

Sexual inactivity and occurrence of STIs in relation to weight status in women: Two large population-based studies.

Gunge VB, Juul KE, van den Brule AJC, Iftner T, Kjær SK.

Women Health. 2018 Aug;58(7):790-805. doi: 10.1080/03630242.2017.1353572. Epub 2017 Aug 25.

PMID:
28742991
4.

High-risk human papillomavirus detection in self-sampling compared to physician-taken smear in a responder population of the Dutch cervical screening: Results of the VERA study.

Ketelaars PJW, Bosgraaf RP, Siebers AG, Massuger LFAG, van der Linden JC, Wauters CAP, Rahamat-Langendoen JC, van den Brule AJC, IntHout J, Melchers WJG, Bekkers RLM.

Prev Med. 2017 Aug;101:96-101. doi: 10.1016/j.ypmed.2017.05.021. Epub 2017 Jun 1.

5.

High pneumococcal DNA load, procalcitonin and suPAR levels correlate to severe disease development in patients with pneumococcal pneumonia.

Loonen AJM, Kesarsing C, Kusters R, Hilbink M, Wever PC, van den Brule AJC.

Eur J Clin Microbiol Infect Dis. 2017 Sep;36(9):1541-1547. doi: 10.1007/s10096-017-2963-2. Epub 2017 Mar 29.

PMID:
28353184
6.

HPV Prevalence in the Dutch cervical cancer screening population (DuSC study): HPV testing using automated HC2, cobas and Aptima workflows.

Huijsmans CJ, Geurts-Giele WR, Leeijen C, Hazenberg HL, van Beek J, de Wild C, van der Linden JC, van den Brule AJ.

BMC Cancer. 2016 Nov 28;16(1):922.

7.

Multidisciplinary molecular diagnostics: the 9th European meeting on molecular diagnostics.

Loonen AJ, Schuurman R, van den Brule AJ.

Expert Rev Mol Diagn. 2016;16(4):395-7. doi: 10.1586/14737159.2016.1152185. Epub 2016 Feb 26.

PMID:
26854825
8.

Allelic imbalance at the HER2/TOP2A locus in breast cancer.

Huijsmans CJ, van den Brule AJ, Rigter H, Poodt J, van der Linden JC, Savelkoul PH, Hilbink M, Hermans MH.

Diagn Pathol. 2015 May 29;10:56. doi: 10.1186/s13000-015-0289-x.

9.

Correlation of haloperidol concentration in blood and cerebrospinal fluid: a pharmacokinetic study.

van Strien AM, Vermeulen Windsant-van den Tweel A, Leliveld-van den Heuvel M, di Biase M, van den Brule AJ, van Marum RJ.

J Clin Psychopharmacol. 2014 Aug;34(4):516-7. doi: 10.1097/JCP.0000000000000125. No abstract available.

PMID:
24875078
10.

Developments for improved diagnosis of bacterial bloodstream infections.

Loonen AJ, Wolffs PF, Bruggeman CA, van den Brule AJ.

Eur J Clin Microbiol Infect Dis. 2014 Oct;33(10):1687-702. doi: 10.1007/s10096-014-2153-4. Epub 2014 May 22. Review.

PMID:
24848132
11.

Biomarkers and molecular analysis to improve bloodstream infection diagnostics in an emergency care unit.

Loonen AJ, de Jager CP, Tosserams J, Kusters R, Hilbink M, Wever PC, van den Brule AJ.

PLoS One. 2014 Jan 27;9(1):e87315. doi: 10.1371/journal.pone.0087315. eCollection 2014.

12.

Comparison of pathogen DNA isolation methods from large volumes of whole blood to improve molecular diagnosis of bloodstream infections.

Loonen AJ, Bos MP, van Meerbergen B, Neerken S, Catsburg A, Dobbelaer I, Penterman R, Maertens G, van de Wiel P, Savelkoul P, van den Brule AJ.

PLoS One. 2013 Aug 15;8(8):e72349. doi: 10.1371/journal.pone.0072349. eCollection 2013.

13.

Multiple-type human papillomavirus infection in younger uncircumcised men.

Nielsen A, Munk C, Jørgensen HO, Winther JF, van den Brule AJ, Kjaer SK.

Int J STD AIDS. 2013 Feb;24(2):128-33. doi: 10.1177/0956462412472294. Epub 2013 May 6.

PMID:
23512509
14.

Comparative study using phenotypic, genotypic, and proteomics methods for identification of coagulase-negative staphylococci.

Loonen AJ, Jansz AR, Bergland JN, Valkenburg M, Wolffs PF, van den Brule AJ.

J Clin Microbiol. 2012 Apr;50(4):1437-9. doi: 10.1128/JCM.06746-11. Epub 2012 Jan 11.

15.

Highlights from the 7th European meeting on molecular diagnostics.

Loonen AJ, Schuurman R, van den Brule AJ.

Expert Rev Mol Diagn. 2012 Jan;12(1):17-9. doi: 10.1586/erm.11.89.

PMID:
22133115
16.

An evaluation of three processing methods and the effect of reduced culture times for faster direct identification of pathogens from BacT/ALERT blood cultures by MALDI-TOF MS.

Loonen AJ, Jansz AR, Stalpers J, Wolffs PF, van den Brule AJ.

Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1575-83. doi: 10.1007/s10096-011-1480-y. Epub 2011 Nov 12.

17.

Pharmacogenetics of oxaliplatin as adjuvant treatment in colon carcinoma: are single nucleotide polymorphisms in GSTP1, ERCC1, and ERCC2 good predictive markers?

Fariña Sarasqueta A, van Lijnschoten G, Lemmens VE, Rutten HJ, van den Brule AJ.

Mol Diagn Ther. 2011 Oct 1;15(5):277-83. doi: 10.2165/11592080-000000000-00000.

PMID:
21958378
18.

EGFR and KRAS quality assurance schemes in pathology: generating normative data for molecular predictive marker analysis in targeted therapy.

Thunnissen E, Bovée JV, Bruinsma H, van den Brule AJ, Dinjens W, Heideman DA, Meulemans E, Nederlof P, van Noesel C, Prinsen CF, Scheidel K, van de Ven PM, de Weger R, Schuuring E, Ligtenberg M.

J Clin Pathol. 2011 Oct;64(10):884-92. doi: 10.1136/jclinpath-2011-200163.

PMID:
21947301
19.

PIK3CA kinase domain mutation identifies a subgroup of stage III colon cancer patients with poor prognosis.

Fariña Sarasqueta A, Zeestraten EC, van Wezel T, van Lijnschoten G, van Eijk R, Dekker JW, Kuppen PJ, Goossens-Beumer IJ, Lemmens VE, van de Velde CJ, Rutten HJ, Morreau H, van den Brule AJ.

Cell Oncol (Dordr). 2011 Dec;34(6):523-31. doi: 10.1007/s13402-011-0054-4. Epub 2011 Aug 10.

PMID:
21830111
20.

TS gene polymorphisms are not good markers of response to 5-FU therapy in stage III colon cancer patients.

Fariña-Sarasqueta A, Gosens MJ, Moerland E, van Lijnschoten I, Lemmens VE, Slooter GD, Rutten HJ, van den Brule AJ.

Cell Oncol (Dordr). 2011 Aug;34(4):327-35. doi: 10.1007/s13402-011-0030-z. Epub 2011 Jun 1.

PMID:
21630057
21.

SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.

Fariña Sarasqueta A, Moerland E, de Bruyne H, de Graaf H, Vrancken T, van Lijnschoten G, van den Brule AJ.

J Mol Diagn. 2011 Mar;13(2):199-205. doi: 10.1016/j.jmoldx.2010.10.006.

22.

Rapid genotyping of human papillomavirus by post-PCR array-based hybridization techniques.

Pierik A, Zwanenburg C, Moerland E, Broer D, Stapert H, van den Brule AJ.

J Clin Microbiol. 2011 Apr;49(4):1395-402. doi: 10.1128/JCM.01606-10. Epub 2011 Feb 16.

23.

Acceleration of the direct identification of Staphylococcus aureus versus coagulase-negative staphylococci from blood culture material: a comparison of six bacterial DNA extraction methods.

Loonen AJ, Jansz AR, Kreeftenberg H, Bruggeman CA, Wolffs PF, van den Brule AJ.

Eur J Clin Microbiol Infect Dis. 2011 Mar;30(3):337-42. doi: 10.1007/s10096-010-1090-0. Epub 2010 Oct 24.

24.

TS gene polymorphisms are not good markers of response to 5-FU therapy in stage III colon cancer patients.

Fariña-Sarasqueta A, Gosens MJ, Moerland E, van Lijnschoten I, Lemmens VE, Slooter GD, Rutten HJ, van den Brule AJ.

Anal Cell Pathol (Amst). 2010;33(1):1-11. doi: 10.3233/ACP-CLO-2010-0526. Erratum in: Cell Oncol (Dordr). 2011 Aug;34(4):407-8.

25.

Value of gene polymorphisms as markers of 5-FU therapy response in stage III colon carcinoma: a pilot study.

Fariña-Sarasqueta A, van Lijnschoten G, Rutten HJ, van den Brule AJ.

Cancer Chemother Pharmacol. 2010 Nov;66(6):1167-71. doi: 10.1007/s00280-010-1403-0. Epub 2010 Jul 28.

PMID:
20665215
26.

The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients.

Fariña-Sarasqueta A, van Lijnschoten G, Moerland E, Creemers GJ, Lemmens VE, Rutten HJ, van den Brule AJ.

Ann Oncol. 2010 Dec;21(12):2396-402. doi: 10.1093/annonc/mdq258. Epub 2010 May 25.

PMID:
20501503
27.

Evaluation of MeningoFinder, a novel multiplex ligation-dependent probe amplification assay for simultaneous detection of six virus species causing central nervous system infections.

Wolffs PF, Vink C, Keijdener J, Habek B, Reijans M, Simons G, Bruggeman CA, van den Brule AJ.

J Clin Microbiol. 2009 Aug;47(8):2620-2. doi: 10.1128/JCM.02436-08. Epub 2009 Jun 24.

28.

Local recurrence in rectal cancer can be predicted by histopathological factors.

Dresen RC, Peters EE, Rutten HJ, Nieuwenhuijzen GA, Demeyere TB, van den Brule AJ, Kessels AG, Beets-Tan RG, van Krieken JH, Nagtegaal ID.

Eur J Surg Oncol. 2009 Oct;35(10):1071-7. doi: 10.1016/j.ejso.2009.03.007. Epub 2009 Apr 11.

PMID:
19364631
29.

Patterns of local recurrence in locally advanced rectal cancer after intra-operative radiotherapy containing multimodality treatment.

Kusters M, Holman FA, Martijn H, Nieuwenhuijzen GA, Creemers GJ, Daniels-Gooszen AW, van den Berg HA, van den Brule AJ, van de Velde CJ, Rutten HJ.

Radiother Oncol. 2009 Aug;92(2):221-5. doi: 10.1016/j.radonc.2009.03.002. Epub 2009 Mar 30.

PMID:
19339070
30.

Histological characteristics of human papilloma-virus-positive and -negative invasive and in situ squamous cell tumours of the penis.

Krustrup D, Jensen HL, van den Brule AJ, Frisch M.

Int J Exp Pathol. 2009 Apr;90(2):182-9. doi: 10.1111/j.1365-2613.2008.00636.x.

31.

Neoadjuvant radiochemotherapy increases matrix metalloproteinase activity in healthy tissue in esophageal cancer patients.

Rieff EA, Hendriks T, Rutten HJ, Nieuwenhuijzen GA, Gosens MJ, van den Brule AJ, Nienhuijs SW, de Hingh IH.

Ann Surg Oncol. 2009 May;16(5):1384-9. doi: 10.1245/s10434-009-0365-0. Epub 2009 Feb 18.

PMID:
19224281
32.

Risk factors for squamous cell carcinoma of the penis--population-based case-control study in Denmark.

Madsen BS, van den Brule AJ, Jensen HL, Wohlfahrt J, Frisch M.

Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2683-91. doi: 10.1158/1055-9965.EPI-08-0456.

33.

Preoperative radiochemotherapy is successful also in patients with locally advanced rectal cancer who have intrinsically high apoptotic tumours.

Gosens MJ, Dresen RC, Rutten HJ, Nieuwenhuijzen GA, van der Laak JA, Martijn H, Tan-Go I, Nagtegaal ID, van den Brule AJ, van Krieken JH.

Ann Oncol. 2008 Dec;19(12):2026-32. doi: 10.1093/annonc/mdn428. Epub 2008 Jul 29.

34.

Thymidylate synthase genotyping is more predictive for therapy response than immunohistochemistry in patients with colon cancer.

Gosens MJ, Moerland E, Lemmens VP, Rutten HT, Tan-Go I, van den Brule AJ.

Int J Cancer. 2008 Oct 15;123(8):1941-9. doi: 10.1002/ijc.23740.

35.

Increased infiltration of Chlamydophila pneumoniae in the vessel wall of human veins after perfusion.

Kupreishvili K, ter Weeme M, Morré SA, van den Brule AJ, Huybregts MA, Quax PH, ten Velden J, Van Hinsbergh VW, Stooker W, Eijsman L, Niessen HW.

Eur J Clin Invest. 2008 Jul;38(7):462-8. doi: 10.1111/j.1365-2362.2008.01961.x. Epub 2008 May 16.

PMID:
18489582
36.

Radical resection after IORT-containing multimodality treatment is the most important determinant for outcome in patients treated for locally recurrent rectal cancer.

Dresen RC, Gosens MJ, Martijn H, Nieuwenhuijzen GA, Creemers GJ, Daniels-Gooszen AW, van den Brule AJ, van den Berg HA, Rutten HJ.

Ann Surg Oncol. 2008 Jul;15(7):1937-47. doi: 10.1245/s10434-008-9896-z. Epub 2008 Apr 4.

37.

Risk factors for invasive squamous cell carcinoma of the vulva and vagina--population-based case-control study in Denmark.

Madsen BS, Jensen HL, van den Brule AJ, Wohlfahrt J, Frisch M.

Int J Cancer. 2008 Jun 15;122(12):2827-34. doi: 10.1002/ijc.23446.

38.

Circumferential margin involvement is the crucial prognostic factor after multimodality treatment in patients with locally advanced rectal carcinoma.

Gosens MJ, Klaassen RA, Tan-Go I, Rutten HJ, Martijn H, van den Brule AJ, Nieuwenhuijzen GA, van Krieken JH, Nagtegaal ID.

Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6617-23.

39.

Multicenter comparison of molecular methods for detection of Legionella spp. in sputum samples.

Bencini MA, van den Brule AJ, Claas EC, Hermans MH, Melchers WJ, Noordhoek GT, Salimans MM, Schirm J, Vink C, van der Zee A, Jansen R.

J Clin Microbiol. 2007 Oct;45(10):3390-2. Epub 2007 Aug 1.

40.

Cyclooxygenase 2 expression in rectal cancer is of prognostic significance in patients receiving preoperative radiotherapy.

de Heer P, Gosens MJ, de Bruin EC, Dekker-Ensink NG, Putter H, Marijnen CA, van den Brule AJ, van Krieken JH, Rutten HJ, Kuppen PJ, van de Velde CJ; Dutch Colorectal Cancer Group.

Clin Cancer Res. 2007 May 15;13(10):2955-60.

41.

[A pseudo-outbreak of pharyngeal gonorrhoea related to a false-positive PCR-result].

Verzijl A, Berretty PJ, Erceg A, Krekels GA, Van den Brule AJ, Boel CH.

Ned Tijdschr Geneeskd. 2007 Mar 24;151(12):689-91. Review. Dutch.

PMID:
17447594
43.

The role of smoking and alcohol intake in the development of high-grade squamous intraepithelial lesions among high-risk HPV-positive women.

Tolstrup J, Munk C, Thomsen BL, Svare E, van den Brule AJ, Grønbaek M, Meijer C, Kjaer Krüger S.

Acta Obstet Gynecol Scand. 2006;85(9):1114-9.

PMID:
16929418
44.

HPV DNA detection and typing in cervical scrapes.

Snijders PJ, van den Brule AJ, Jacobs MV, Pol RP, Meijer CJ.

Methods Mol Med. 2005;119:101-14.

PMID:
16350400
45.

Morphological evidence of an activated cytotoxic T-cell infiltrate in EBV-positive gastric carcinoma preventing lymph node metastases.

van Beek J, zur Hausen A, Snel SN, Berkhof J, Kranenbarg EK, van de Velde CJ, van den Brule AJ, Middeldorp JM, Meijer CJ, Bloemena E.

Am J Surg Pathol. 2006 Jan;30(1):59-65.

PMID:
16330943
46.

Specific and sensitive detection of Neisseria gonorrhoeae in clinical specimens by real-time PCR.

Geraats-Peters CW, Brouwers M, Schneeberger PM, van der Zanden AG, Bruisten SM, Weers-Pothoff G, Boel CH, van den Brule AJ, Harmsen HG, Hermans MH.

J Clin Microbiol. 2005 Nov;43(11):5653-9.

47.

Comparison of three different PCR methods for quantifying human papillomavirus type 16 DNA in cervical scrape specimens.

Hesselink AT, van den Brule AJ, Groothuismink ZM, Molano M, Berkhof J, Meijer CJ, Snijders PJ.

J Clin Microbiol. 2005 Sep;43(9):4868-71.

48.

Cervical coinfection with human papillomavirus (HPV) types and possible implications for the prevention of cervical cancer by HPV vaccines.

Mendez F, Munoz N, Posso H, Molano M, Moreno V, van den Brule AJ, Ronderos M, Meijer C, Munoz A; Instituto Nacional de Cancerologia Human Papillomavirus Study Group.

J Infect Dis. 2005 Oct 1;192(7):1158-65. Epub 2005 Aug 29.

PMID:
16136457
49.

Concordance of specific human papillomavirus types in sex partners is more prevalent than would be expected by chance and is associated with increased viral loads.

Bleeker MC, Hogewoning CJ, Berkhof J, Voorhorst FJ, Hesselink AT, van Diemen PM, van den Brule AJ, Snijders PJ, Meijer CJ.

Clin Infect Dis. 2005 Sep 1;41(5):612-20. Epub 2005 Jul 25.

PMID:
16080082
50.

Acquisition and persistence of human papillomavirus infection in younger men: a prospective follow-up study among Danish soldiers.

Kjaer SK, Munk C, Winther JF, Jørgensen HO, Meijer CJ, van den Brule AJ.

Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1528-33.

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