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Items: 1 to 50 of 315

1.

The Genetic Makeup and Expression of the Glycolytic and Fermentative Pathways Are Highly Conserved Within the Saccharomyces Genus.

Boonekamp FJ, Dashko S, van den Broek M, Gehrmann T, Daran JM, Daran-Lapujade P.

Front Genet. 2018 Nov 16;9:504. doi: 10.3389/fgene.2018.00504. eCollection 2018.

2.

Allele-specific genome editing using CRISPR-Cas9 is associated with loss of heterozygosity in diploid yeast.

Gorter de Vries AR, Couwenberg LGF, van den Broek M, de la Torre Cortés P, Ter Horst J, Pronk JT, Daran JG.

Nucleic Acids Res. 2018 Dec 5. doi: 10.1093/nar/gky1216. [Epub ahead of print]

PMID:
30517747
3.

Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.

Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B.

Sci Transl Med. 2018 Nov 28;10(469). pii: eaat8410. doi: 10.1126/scitranslmed.aat8410.

PMID:
30487251
4.

Prevalence and pathophysiology of early dumping in patients after primary Roux-en-Y gastric bypass during a mixed-meal tolerance test.

Wijma RB MD, Emous M MD, van den Broek M MD, Laskewitz A PhD, Kobold ACM PhD, van Beek AP PhD.

Surg Obes Relat Dis. 2018 Oct 12. pii: S1550-7289(18)30392-7. doi: 10.1016/j.soard.2018.10.004. [Epub ahead of print]

PMID:
30446401
5.

A toolkit for rapid CRISPR-SpCas9 assisted construction of hexose-transport-deficient Saccharomyces cerevisiae strains.

Wijsman M, Swiat MA, Marques WL, Hettinga JK, van den Broek M, Torre Cortés P, Mans R, Pronk JT, Daran JM, Daran-Lapujade P.

FEMS Yeast Res. 2019 Jan 1;19(1). doi: 10.1093/femsyr/foy107.

6.

Laboratory evolution and physiological analysis of Saccharomyces cerevisiae strains dependent on sucrose uptake via the Phaseolus vulgaris Suf1 transporter.

Marques WL, van der Woude LN, Luttik MAH, van den Broek M, Nijenhuis JM, Pronk JT, van Maris AJA, Mans R, Gombert AK.

Yeast. 2018 Dec;35(12):639-652. doi: 10.1002/yea.3357. Epub 2018 Oct 15.

PMID:
30221387
7.

Gemcitabine Synergizes with Immune Checkpoint Inhibitors and Overcomes Resistance in a Preclinical Model and Mesothelioma Patients.

Tallón de Lara P, Cecconi V, Hiltbrunner S, Yagita H, Friess M, Bode B, Opitz I, Vrugt B, Weder W, Stolzmann P, Felley-Bosco E, Stahel RA, Tischler V, Britschgi C, Soldini D, van den Broek M, Curioni-Fontecedro A.

Clin Cancer Res. 2018 Dec 15;24(24):6345-6354. doi: 10.1158/1078-0432.CCR-18-1231. Epub 2018 Aug 28.

PMID:
30154226
8.

Structural, Physiological and Regulatory Analysis of Maltose Transporter Genes in Saccharomyces eubayanus CBS 12357T.

Brickwedde A, Brouwers N, van den Broek M, Gallego Murillo JS, Fraiture JL, Pronk JT, Daran JG.

Front Microbiol. 2018 Aug 10;9:1786. doi: 10.3389/fmicb.2018.01786. eCollection 2018.

9.

A Quantitative Pathology Approach to Analyze the Development of Human Cancer-Associated Tertiary Lymphoid Structures.

Siliņa K, Burkhardt C, Casanova R, Solterman A, van den Broek M.

Methods Mol Biol. 2018;1845:71-86. doi: 10.1007/978-1-4939-8709-2_5.

PMID:
30141008
10.

Selection of Pof-Saccharomyces eubayanus Variants for the Construction of S. cerevisiae × S. eubayanus Hybrids With Reduced 4-Vinyl Guaiacol Formation.

Diderich JA, Weening SM, van den Broek M, Pronk JT, Daran JG.

Front Microbiol. 2018 Jul 27;9:1640. doi: 10.3389/fmicb.2018.01640. eCollection 2018.

11.

Good and Bad Sides of Self-Compassion: A Face Validity Check of the Self-Compassion Scale and an Investigation of its Relations to Coping and Emotional Symptoms in Non-Clinical Adolescents.

Muris P, van den Broek M, Otgaar H, Oudenhoven I, Lennartz J.

J Child Fam Stud. 2018;27(8):2411-2421. doi: 10.1007/s10826-018-1099-z. Epub 2018 May 4.

12.

Engineering Lactobacillus rhamnosus GG and GR-1 to express HIV-inhibiting griffithsin.

Petrova MI, van den Broek MFL, Spacova I, Verhoeven TLA, Balzarini J, Vanderleyden J, Schols D, Lebeer S.

Int J Antimicrob Agents. 2018 Nov;52(5):599-607. doi: 10.1016/j.ijantimicag.2018.07.013. Epub 2018 Jul 21.

PMID:
30040991
13.

A local uPAR-plasmin-TGFβ1 positive feedback loop in a qualitative computational model of angiogenic sprouting explains the in vitro effect of fibrinogen variants.

Boas SEM, Carvalho J, van den Broek M, Weijers EM, Goumans MJ, Koolwijk P, Merks RMH.

PLoS Comput Biol. 2018 Jul 6;14(7):e1006239. doi: 10.1371/journal.pcbi.1006239. eCollection 2018 Jul.

14.

Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation.

Arnold IC, Artola-Borán M, Tallón de Lara P, Kyburz A, Taube C, Ottemann K, van den Broek M, Yousefi S, Simon HU, Müller A.

J Exp Med. 2018 Aug 6;215(8):2055-2072. doi: 10.1084/jem.20172049. Epub 2018 Jul 3.

PMID:
29970473
15.

Satiety and gastrointestinal hormones during a Mixed Meal Tolerance Test after gastric bypass surgery: association with plasma amino acid concentrations.

van den Broek M, de Heide LJM, Emous M, Wijma RB, Veeger NJGM, Wolthuis A, Laskewitz AJ, Heiner-Fokkema MR, Muller Kobold AC, Wolffenbuttel BHR, van Beek AP.

Surg Obes Relat Dis. 2018 Aug;14(8):1106-1117. doi: 10.1016/j.soard.2018.05.010. Epub 2018 May 21.

PMID:
29937240
16.

CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis.

Beffinger M, Tallón de Lara P, Tugues S, Vermeer M, Montagnolo Y, Ohs I, Cecconi V, Lucchiari G, Gagliardi A, Misljencevic N, Sutton J, Spörri R, Becher B, Gupta A, van den Broek M.

JCI Insight. 2018 May 17;3(10). pii: 97792. doi: 10.1172/jci.insight.97792. [Epub ahead of print]

17.

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma.

Zimmerli D, Cecconi V, Valenta T, Hausmann G, Cantù C, Restivo G, Hafner J, Basler K, van den Broek M.

Oncogene. 2018 Jul;37(27):3753-3762. doi: 10.1038/s41388-018-0244-x. Epub 2018 Apr 17.

18.

Multifactorial inhibition of lactobacilli against the respiratory tract pathogen Moraxella catarrhalis.

van den Broek MFL, De Boeck I, Claes IJJ, Nizet V, Lebeer S.

Benef Microbes. 2018 Apr 25;9(3):429-439. doi: 10.3920/BM2017.0101. Epub 2018 Apr 10.

PMID:
29633637
19.

Lymphopenia in atopic dermatitis patients treated with oral immunosuppressive drugs.

Bakker DS, Garritsen FM, Leavis HL, van der Schaft J, Bruijnzeel-Koomen CAFM, van den Broek MPH, de Bruin-Weller MS.

J Dermatolog Treat. 2018 Nov;29(7):682-687. doi: 10.1080/09546634.2018.1451619. Epub 2018 Mar 28.

PMID:
29526121
20.

Use of oral immunosuppressive drugs in the treatment of atopic dermatitis in the Netherlands.

Garritsen FM, van den Heuvel JM, Bruijnzeel-Koomen CAFM, Maitland-van der Zee AH, van den Broek MPH, de Bruin-Weller MS.

J Eur Acad Dermatol Venereol. 2018 Feb 27. doi: 10.1111/jdv.14896. [Epub ahead of print]

PMID:
29485224
21.

Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer.

Posch F, Silina K, Leibl S, Mündlein A, Moch H, Siebenhüner A, Samaras P, Riedl J, Stotz M, Szkandera J, Stöger H, Pichler M, Stupp R, van den Broek M, Schraml P, Gerger A, Petrausch U, Winder T.

Oncoimmunology. 2017 Dec 18;7(2):e1378844. doi: 10.1080/2162402X.2017.1378844. eCollection 2018.

22.

Optimizing anaerobic growth rate and fermentation kinetics in Saccharomyces cerevisiae strains expressing Calvin-cycle enzymes for improved ethanol yield.

Papapetridis I, Goudriaan M, Vázquez Vitali M, de Keijzer NA, van den Broek M, van Maris AJA, Pronk JT.

Biotechnol Biofuels. 2018 Jan 25;11:17. doi: 10.1186/s13068-017-1001-z. eCollection 2018.

23.

Germinal Centers Determine the Prognostic Relevance of Tertiary Lymphoid Structures and Are Impaired by Corticosteroids in Lung Squamous Cell Carcinoma.

Siliņa K, Soltermann A, Attar FM, Casanova R, Uckeley ZM, Thut H, Wandres M, Isajevs S, Cheng P, Curioni-Fontecedro A, Foukas P, Levesque MP, Moch H, Linē A, van den Broek M.

Cancer Res. 2018 Mar 1;78(5):1308-1320. doi: 10.1158/0008-5472.CAN-17-1987. Epub 2017 Dec 26.

PMID:
29279354
24.

Comparing the Healthy Nose and Nasopharynx Microbiota Reveals Continuity As Well As Niche-Specificity.

De Boeck I, Wittouck S, Wuyts S, Oerlemans EFM, van den Broek MFL, Vandenheuvel D, Vanderveken O, Lebeer S.

Front Microbiol. 2017 Nov 29;8:2372. doi: 10.3389/fmicb.2017.02372. eCollection 2017.

25.

CRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus.

Gorter de Vries AR, de Groot PA, van den Broek M, Daran JG.

Microb Cell Fact. 2017 Dec 5;16(1):222. doi: 10.1186/s12934-017-0835-1.

26.

Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema.

Garritsen FM, van der Schaft J, de Graaf M, Hijnen DJ, Bruijnzeel-Koomen CAF, van den Broek MPH, De Bruin-Weller MS.

Acta Derm Venereol. 2018 Mar 13;98(3):373-375. doi: 10.2340/00015555-2839. No abstract available.

27.

Enhancing the viability of Lactobacillus rhamnosus GG after spray drying and during storage.

Broeckx G, Vandenheuvel D, Henkens T, Kiekens S, van den Broek MFL, Lebeer S, Kiekens F.

Int J Pharm. 2017 Dec 20;534(1-2):35-41. doi: 10.1016/j.ijpharm.2017.09.075. Epub 2017 Oct 3.

PMID:
28986319
28.

Nanopore sequencing enables near-complete de novo assembly of Saccharomyces cerevisiae reference strain CEN.PK113-7D.

Salazar AN, Gorter de Vries AR, van den Broek M, Wijsman M, de la Torre Cortés P, Brickwedde A, Brouwers N, Daran JG, Abeel T.

FEMS Yeast Res. 2017 Nov 1;17(7). doi: 10.1093/femsyr/fox074.

29.

Evolutionary Engineering in Chemostat Cultures for Improved Maltotriose Fermentation Kinetics in Saccharomyces pastorianus Lager Brewing Yeast.

Brickwedde A, van den Broek M, Geertman JA, Magalhães F, Kuijpers NGA, Gibson B, Pronk JT, Daran JG.

Front Microbiol. 2017 Sep 8;8:1690. doi: 10.3389/fmicb.2017.01690. eCollection 2017.

30.

Thiopurine metabolite levels in patients with atopic dermatitis and/or chronic hand/foot eczema treated with azathioprine.

Garritsen FM, van der Schaft J, Bruijnzeel-Koomen CAF, van Schaik RH, de Graaf M, van den Broek MPH, de Bruin-Weller MS.

J Dermatolog Treat. 2018 Jun;29(4):375-382. doi: 10.1080/09546634.2017.1373738. Epub 2017 Sep 26.

PMID:
28914560
31.

Diffuse pseudoprogression in a patient with metastatic non-small-cell lung cancer treated with Nivolumab.

Curioni-Fontecedro A, Ickenberg C, Franzen D, Rogler G, Burger IA, van den Broek M.

Ann Oncol. 2017 Aug 1;28(8):2040-2041. doi: 10.1093/annonc/mdx233. No abstract available.

PMID:
28838208
32.

Reverse shoulder arthroplasty in young patient with achondroplasia - Ten year follow up: Case report.

van den Broek M, Verborgt O, Declercq G.

Orthop Traumatol Surg Res. 2017 Nov;103(7):1127-1130. doi: 10.1016/j.otsr.2017.07.004. Epub 2017 Aug 5.

33.

Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis.

Willrodt AH, Beffinger M, Vranova M, Protsyuk D, Schuler K, Jadhav M, Heikenwalder M, van den Broek M, Borsig L, Halin C.

Am J Pathol. 2017 Nov;187(11):2558-2569. doi: 10.1016/j.ajpath.2017.07.008. Epub 2017 Aug 17.

34.

Paediatric fractures around the knee.

van den Broek M, Oussedik S.

Br J Hosp Med (Lond). 2017 Aug 2;78(8):453-458. doi: 10.12968/hmed.2017.78.8.453.

PMID:
28783395
35.

Interplay between Lactobacillus rhamnosus GG and Candida and the involvement of exopolysaccharides.

Allonsius CN, van den Broek MFL, De Boeck I, Kiekens S, Oerlemans EFM, Kiekens F, Foubert K, Vandenheuvel D, Cos P, Delputte P, Lebeer S.

Microb Biotechnol. 2017 Nov;10(6):1753-1763. doi: 10.1111/1751-7915.12799. Epub 2017 Aug 3.

36.

Efficacy and safety of collagenase treatment for Dupuytren's disease: 2-year follow-up results.

Van Beeck A, Van den Broek M, Michielsen M, Didden K, Vuylsteke K, Verstreken F.

Hand Surg Rehabil. 2017 Oct;36(5):346-349. doi: 10.1016/j.hansur.2017.06.007. Epub 2017 Jul 18.

PMID:
28732844
37.

Laboratory Evolution of a Biotin-Requiring Saccharomyces cerevisiae Strain for Full Biotin Prototrophy and Identification of Causal Mutations.

Bracher JM, de Hulster E, Koster CC, van den Broek M, Daran JG, van Maris AJA, Pronk JT.

Appl Environ Microbiol. 2017 Aug 1;83(16). pii: e00892-17. doi: 10.1128/AEM.00892-17. Print 2017 Aug 15.

38.

Electromagnetic-guided placement of nasoduodenal feeding tubes versus endoscopic placement: a randomized, multicenter trial.

Kappelle WFW, Walter D, Stadhouders PH, Jebbink HJA, Vleggaar FP, van der Schaar PJ, Kappelle JW, van der Tweel I, Van den Broek MFM, Wessels FJ, Siersema PD, Monkelbaan JF.

Gastrointest Endosc. 2018 Jan;87(1):110-118. doi: 10.1016/j.gie.2017.05.033. Epub 2017 Jun 1.

PMID:
28579349
39.

Intra-articular capacity of the elbow joint.

Van Den Broek M, Van Riet R.

Clin Anat. 2017 Sep;30(6):795-798. doi: 10.1002/ca.22915. Epub 2017 Jun 7.

PMID:
28514501
40.

An Immune Atlas of Clear Cell Renal Cell Carcinoma.

Chevrier S, Levine JH, Zanotelli VRT, Silina K, Schulz D, Bacac M, Ries CH, Ailles L, Jewett MAS, Moch H, van den Broek M, Beisel C, Stadler MB, Gedye C, Reis B, Pe'er D, Bodenmiller B.

Cell. 2017 May 4;169(4):736-749.e18. doi: 10.1016/j.cell.2017.04.016.

41.

Pregnancy and fetal outcomes after paternal exposure to azathioprine, methotrexate or mycophenolic acid: a critically appraised topic.

Garritsen FM, van den Broek MPH, van Zuilen AD, Fidder HH, de Bruin-Weller MS, Spuls PI.

Br J Dermatol. 2017 Apr;176(4):866-877. doi: 10.1111/bjd.15320. Review. No abstract available.

PMID:
28418137
42.

Mutations in PMR1 stimulate xylose isomerase activity and anaerobic growth on xylose of engineered Saccharomyces cerevisiae by influencing manganese homeostasis.

Verhoeven MD, Lee M, Kamoen L, van den Broek M, Janssen DB, Daran JG, van Maris AJ, Pronk JT.

Sci Rep. 2017 Apr 12;7:46155. doi: 10.1038/srep46155.

43.

Corrigendum: Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.

Ohs I, van den Broek M, Nussbaum K, Münz C, Arnold SJ, Quezada SA, Tugues S, Becher B.

Nat Commun. 2017 Apr 4;8:15185. doi: 10.1038/ncomms15185. No abstract available.

44.

Elimination of sucrose transport and hydrolysis in Saccharomyces cerevisiae: a platform strain for engineering sucrose metabolism.

Marques WL, Mans R, Marella ER, Cordeiro RL, van den Broek M, Daran JG, Pronk JT, Gombert AK, van Maris AJ.

FEMS Yeast Res. 2017 Jan 1;17(1). doi: 10.1093/femsyr/fox006.

45.

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis.

Ohs I, van den Broek M, Nussbaum K, Münz C, Arnold SJ, Quezada SA, Tugues S, Becher B.

Nat Commun. 2016 Dec 16;7:13708. doi: 10.1038/ncomms13708.

46.

Pathway swapping: Toward modular engineering of essential cellular processes.

Kuijpers NG, Solis-Escalante D, Luttik MA, Bisschops MM, Boonekamp FJ, van den Broek M, Pronk JT, Daran JM, Daran-Lapujade P.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15060-15065. doi: 10.1073/pnas.1606701113. Epub 2016 Dec 12.

47.

Influence of dietary protein and its amino acid composition on postoperative outcomes after gastric bypass surgery: a systematic review.

van den Broek M, de Heide LJ, Veeger NJ, van der Wal-Oost AM, van Beek AP.

Nutr Rev. 2016 Dec;74(12):749-773. Review.

PMID:
27864536
48.

Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans.

Neis EP, Bloemen JG, Rensen SS, van der Vorst JR, van den Broek MA, Venema K, Buurman WA, Dejong CH.

PLoS One. 2016 Nov 11;11(11):e0166161. doi: 10.1371/journal.pone.0166161. eCollection 2016.

49.

Dosing and therapeutic drug monitoring of voriconazole in bottlenose dolphins (Tursiops truncatus).

Ferrier K, van Elk CE, Bunskoek PE, van den Broek M.

Med Mycol. 2017 Feb 1;55(2):155-163. doi: 10.1093/mmy/myw062. Epub 2016 Oct 4.

PMID:
27703023
50.

Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro.

Nauta TD, van den Broek M, Gibbs S, van der Pouw-Kraan TC, Oudejans CB, van Hinsbergh VW, Koolwijk P.

Angiogenesis. 2017 Feb;20(1):39-54. doi: 10.1007/s10456-016-9527-4. Epub 2016 Oct 3.

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