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Items: 1 to 50 of 55

1.

Species-specific co-localization of MERS-CoV attachment and entry receptors.

Widagdo W, Okba NMA, Li W, de Jong A, de Swart RYL, Begeman L, van den Brand JMA, Bosch BJ, Haagmans BL.

J Virol. 2019 Jun 5. pii: JVI.00107-19. doi: 10.1128/JVI.00107-19. [Epub ahead of print]

PMID:
31167913
2.

Lack of Middle East Respiratory Syndrome Coronavirus Transmission in Rabbits.

Widagdo W, Okba NMA, Richard M, de Meulder D, Bestebroer TM, Lexmond P, Farag EABA, Al-Hajri M, Stittelaar KJ, de Waal L, van Amerongen G, van den Brand JMA, Haagmans BL, Herfst S.

Viruses. 2019 Apr 24;11(4). pii: E381. doi: 10.3390/v11040381.

3.

Beached bachelors: An extensive study on the largest recorded sperm whale Physeter macrocephalus mortality event in the North Sea.

IJsseldijk LL, van Neer A, Deaville R, Begeman L, van de Bildt M, van den Brand JMA, Brownlow A, Czeck R, Dabin W, Ten Doeschate M, Herder V, Herr H, IJzer J, Jauniaux T, Jensen LF, Jepson PD, Jo WK, Lakemeyer J, Lehnert K, Leopold MF, Osterhaus A, Perkins MW, Piatkowski U, Prenger-Berninghoff E, Pund R, Wohlsein P, Gröne A, Siebert U.

PLoS One. 2018 Aug 7;13(8):e0201221. doi: 10.1371/journal.pone.0201221. eCollection 2018.

4.

Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4.

Haverkamp AK, Lehmbecker A, Spitzbarth I, Widagdo W, Haagmans BL, Segalés J, Vergara-Alert J, Bensaid A, van den Brand JMA, Osterhaus ADME, Baumgärtner W.

Sci Rep. 2018 Jun 27;8(1):9778. doi: 10.1038/s41598-018-28109-2.

5.

Wild ducks excrete highly pathogenic avian influenza virus H5N8 (2014-2015) without clinical or pathological evidence of disease.

van den Brand JMA, Verhagen JH, Veldhuis Kroeze EJB, van de Bildt MWG, Bodewes R, Herfst S, Richard M, Lexmond P, Bestebroer TM, Fouchier RAM, Kuiken T.

Emerg Microbes Infect. 2018 Apr 18;7(1):67. doi: 10.1038/s41426-018-0070-9.

6.

Local amplification of highly pathogenic avian influenza H5N8 viruses in wild birds in the Netherlands, 2016 to 2017.

Poen MJ, Bestebroer TM, Vuong O, Scheuer RD, van der Jeugd HP, Kleyheeg E, Eggink D, Lexmond P, van den Brand JMA, Begeman L, van der Vliet S, Müskens GJDM, Majoor FA, Koopmans MPG, Kuiken T, Fouchier RAM.

Euro Surveill. 2018 Jan;23(4). doi: 10.2807/1560-7917.ES.2018.23.4.17-00449.

7.

1918 H1N1 Influenza Virus Replicates and Induces Proinflammatory Cytokine Responses in Extrarespiratory Tissues of Ferrets.

de Wit E, Siegers JY, Cronin JM, Weatherman S, van den Brand JM, Leijten LM, van Run P, Begeman L, van den Ham HJ, Andeweg AC, Bushmaker T, Scott DP, Saturday G, Munster VJ, Feldmann H, van Riel D.

J Infect Dis. 2018 Mar 28;217(8):1237-1246. doi: 10.1093/infdis/jiy003.

8.

Human Clade 2.3.4.4 A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets.

Herfst S, Mok CKP, van den Brand JMA, van der Vliet S, Rosu ME, Spronken MI, Yang Z, de Meulder D, Lexmond P, Bestebroer TM, Peiris JSM, Fouchier RAM, Richard M.

mSphere. 2018 Jan 3;3(1). pii: e00405-17. doi: 10.1128/mSphere.00405-17. eCollection 2018 Jan-Feb.

9.

The Role of B Cells in Carriage and Clearance of Mycoplasma pneumoniae From the Respiratory Tract of Mice.

Meyer Sauteur PM, de Groot RCA, Estevão SC, Hoogenboezem T, de Bruijn ACJM, Sluijter M, de Bruijn MJW, De Kleer IM, van Haperen R, van den Brand JMA, Bogaert D, Fraaij PLA, Vink C, Hendriks RW, Samsom JN, Unger WWJ, van Rossum AMC.

J Infect Dis. 2018 Jan 4;217(2):298-309. doi: 10.1093/infdis/jix559.

10.

Proinflammatory Cytokine Responses in Extra-Respiratory Tissues During Severe Influenza.

Short KR, Veeris R, Leijten LM, van den Brand JM, Jong VL, Stittelaar K, Osterhaus ADME, Andeweg A, van Riel D.

J Infect Dis. 2017 Oct 17;216(7):829-833. doi: 10.1093/infdis/jix281.

PMID:
28973159
11.

Mutations Driving Airborne Transmission of A/H5N1 Virus in Mammals Cause Substantial Attenuation in Chickens only when combined.

Richard M, Herfst S, van den Brand JMA, de Meulder D, Lexmond P, Bestebroer TM, Fouchier RAM.

Sci Rep. 2017 Aug 3;7(1):7187. doi: 10.1038/s41598-017-07000-6.

12.

Tissue Distribution of the MERS-Coronavirus Receptor in Bats.

Widagdo W, Begeman L, Schipper D, Run PRV, Cunningham AA, Kley N, Reusken CB, Haagmans BL, van den Brand JMA.

Sci Rep. 2017 Apr 26;7(1):1193. doi: 10.1038/s41598-017-01290-6.

13.

Norovirus Infection in Harbor Porpoises.

de Graaf M, Bodewes R, van Elk CE, van de Bildt M, Getu S, Aron GI, Verjans GM, Osterhaus AD, van den Brand JM, Kuiken T, Koopmans MP.

Emerg Infect Dis. 2017 Jan;23(1):87-91. doi: 10.3201/eid2301.161081.

14.

Livestock Susceptibility to Infection with Middle East Respiratory Syndrome Coronavirus.

Vergara-Alert J, van den Brand JM, Widagdo W, Muñoz M 5th, Raj S, Schipper D, Solanes D, Cordón I, Bensaid A, Haagmans BL, Segalés J.

Emerg Infect Dis. 2017 Feb;23(2):232-240. doi: 10.3201/eid2302.161239. Epub 2017 Feb 15.

15.

Vaccination Is More Effective Than Prophylactic Oseltamivir in Preventing CNS Invasion by H5N1 Virus via the Olfactory Nerve.

Siegers JY, van den Brand JM, Leijten LM, van de Bildt MM, van Run PR, van Amerongen G, Stittelaar KJ, Koopmans MP, Osterhaus AD, Kuiken T, van Riel D.

J Infect Dis. 2016 Aug 15;214(4):516-24. doi: 10.1093/infdis/jiw123. Epub 2016 Apr 1.

PMID:
27448390
16.

Influenza A (H10N7) Virus Causes Respiratory Tract Disease in Harbor Seals and Ferrets.

van den Brand JM, Wohlsein P, Herfst S, Bodewes R, Pfankuche VM, van de Bildt MW, Seehusen F, Puff C, Richard M, Siebert U, Lehnert K, Bestebroer T, Lexmond P, Fouchier RA, Prenger-Berninghoff E, Herbst W, Koopmans M, Osterhaus AD, Kuiken T, Baumgärtner W.

PLoS One. 2016 Jul 22;11(7):e0159625. doi: 10.1371/journal.pone.0159625. eCollection 2016.

17.

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

Leist SR, Pilzner C, van den Brand JM, Dengler L, Geffers R, Kuiken T, Balling R, Kollmus H, Schughart K.

BMC Genomics. 2016 Feb 27;17:143. doi: 10.1186/s12864-016-2483-y.

18.

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.

Kühn N, Bergmann S, Kösterke N, Lambertz RLO, Keppner A, van den Brand JMA, Pöhlmann S, Weiß S, Hummler E, Hatesuer B, Schughart K.

J Virol. 2016 Apr 14;90(9):4298-4307. doi: 10.1128/JVI.02693-15. Print 2016 May.

19.

Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels.

Widagdo W, Raj VS, Schipper D, Kolijn K, van Leenders GJLH, Bosch BJ, Bensaid A, Segalés J, Baumgärtner W, Osterhaus ADME, Koopmans MP, van den Brand JMA, Haagmans BL.

J Virol. 2016 Apr 14;90(9):4838-4842. doi: 10.1128/JVI.02994-15. Print 2016 May.

20.

An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels.

Haagmans BL, van den Brand JM, Raj VS, Volz A, Wohlsein P, Smits SL, Schipper D, Bestebroer TM, Okba N, Fux R, Bensaid A, Solanes Foz D, Kuiken T, Baumgärtner W, Segalés J, Sutter G, Osterhaus AD.

Science. 2016 Jan 1;351(6268):77-81. doi: 10.1126/science.aad1283. Epub 2015 Dec 17.

21.

Evolutionary origins of hepatitis A virus in small mammals.

Drexler JF, Corman VM, Lukashev AN, van den Brand JM, Gmyl AP, Brünink S, Rasche A, Seggewiβ N, Feng H, Leijten LM, Vallo P, Kuiken T, Dotzauer A, Ulrich RG, Lemon SM, Drosten C; Hepatovirus Ecology Consortium.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15190-5. doi: 10.1073/pnas.1516992112. Epub 2015 Nov 2.

22.

One health, multiple challenges: The inter-species transmission of influenza A virus.

Short KR, Richard M, Verhagen JH, van Riel D, Schrauwen EJ, van den Brand JM, Mänz B, Bodewes R, Herfst S.

One Health. 2015 Dec 1;1:1-13.

23.

Low Virulence and Lack of Airborne Transmission of the Dutch Highly Pathogenic Avian Influenza Virus H5N8 in Ferrets.

Richard M, Herfst S, van den Brand JM, Lexmond P, Bestebroer TM, Rimmelzwaan GF, Koopmans M, Kuiken T, Fouchier RA.

PLoS One. 2015 Jun 19;10(6):e0129827. doi: 10.1371/journal.pone.0129827. eCollection 2015.

24.

Host-specific exposure and fatal neurologic disease in wild raptors from highly pathogenic avian influenza virus H5N1 during the 2006 outbreak in Germany.

van den Brand JM, Krone O, Wolf PU, van de Bildt MW, van Amerongen G, Osterhaus AD, Kuiken T.

Vet Res. 2015 Mar 5;46:24. doi: 10.1186/s13567-015-0148-5.

25.

Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits.

Haagmans BL, van den Brand JM, Provacia LB, Raj VS, Stittelaar KJ, Getu S, de Waal L, Bestebroer TM, van Amerongen G, Verjans GM, Fouchier RA, Smits SL, Kuiken T, Osterhaus AD.

J Virol. 2015 Jun;89(11):6131-5. doi: 10.1128/JVI.00661-15. Epub 2015 Mar 25.

26.

Pathogenesis of Middle East respiratory syndrome coronavirus.

van den Brand JM, Smits SL, Haagmans BL.

J Pathol. 2015 Jan;235(2):175-84. doi: 10.1002/path.4458. Review.

PMID:
25294366
27.

Viral metagenomic analysis of feces of wild small carnivores.

Bodewes R, Ruiz-Gonzalez A, Schapendonk CM, van den Brand JM, Osterhaus AD, Smits SL.

Virol J. 2014 May 15;11:89. doi: 10.1186/1743-422X-11-89.

28.

Activation of coagulation and tissue fibrin deposition in experimental influenza in ferrets.

Goeijenbier M, van Gorp EC, Van den Brand JM, Stittelaar K, Bakhtiari K, Roelofs JJ, van Amerongen G, Kuiken T, Martina BE, Meijers JC, Osterhaus AD.

BMC Microbiol. 2014 May 30;14:134. doi: 10.1186/1471-2180-14-134.

29.

The pathology and pathogenesis of experimental severe acute respiratory syndrome and influenza in animal models.

van den Brand JM, Haagmans BL, van Riel D, Osterhaus AD, Kuiken T.

J Comp Pathol. 2014 Jul;151(1):83-112. doi: 10.1016/j.jcpa.2014.01.004. Epub 2014 Jan 15. Review.

30.

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus.

Raj VS, Smits SL, Provacia LB, van den Brand JM, Wiersma L, Ouwendijk WJ, Bestebroer TM, Spronken MI, van Amerongen G, Rottier PJ, Fouchier RA, Bosch BJ, Osterhaus AD, Haagmans BL.

J Virol. 2014 Feb;88(3):1834-8. doi: 10.1128/JVI.02935-13. Epub 2013 Nov 20.

31.

Limited airborne transmission of H7N9 influenza A virus between ferrets.

Richard M, Schrauwen EJ, de Graaf M, Bestebroer TM, Spronken MI, van Boheemen S, de Meulder D, Lexmond P, Linster M, Herfst S, Smith DJ, van den Brand JM, Burke DF, Kuiken T, Rimmelzwaan GF, Osterhaus AD, Fouchier RA.

Nature. 2013 Sep 26;501(7468):560-3. doi: 10.1038/nature12476. Epub 2013 Aug 7.

32.

Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets.

van den Brand JM, Stittelaar KJ, van Amerongen G, Reperant L, de Waal L, Osterhaus AD, Kuiken T.

PLoS One. 2012;7(8):e42343. doi: 10.1371/journal.pone.0042343. Epub 2012 Aug 8.

33.

Modification of the ferret model for pneumonia from seasonal human influenza A virus infection.

van den Brand JM, Stittelaar KJ, Leijten LM, van Amerongen G, Simon JH, Osterhaus AD, Kuiken T.

Vet Pathol. 2012 May;49(3):562-8. doi: 10.1177/0300985811429812. Epub 2012 Jan 18.

PMID:
22262355
34.

Metagenomic analysis of the viral flora of pine marten and European badger feces.

van den Brand JM, van Leeuwen M, Schapendonk CM, Simon JH, Haagmans BL, Osterhaus AD, Smits SL.

J Virol. 2012 Feb;86(4):2360-5. doi: 10.1128/JVI.06373-11. Epub 2011 Dec 14.

35.

Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species.

Smits SL, van den Brand JM, de Lang A, Leijten LM, van Ijcken WF, van Amerongen G, Osterhaus AD, Andeweg AC, Haagmans BL.

J Virol. 2011 May;85(9):4234-45. doi: 10.1128/JVI.02395-10. Epub 2011 Feb 16.

36.

Pandemic H1N1 vaccine requires the use of an adjuvant to protect against challenge in naïve ferrets.

Baras B, de Waal L, Stittelaar KJ, Jacob V, Giannini S, Kroeze EJ, van den Brand JM, van Amerongen G, Simon JH, Hanon E, Mossman SP, Osterhaus AD.

Vaccine. 2011 Mar 3;29(11):2120-6. doi: 10.1016/j.vaccine.2010.12.125. Epub 2011 Jan 14.

PMID:
21238573
37.

Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets.

van den Brand JM, Kreijtz JH, Bodewes R, Stittelaar KJ, van Amerongen G, Kuiken T, Simon J, Fouchier RA, Del Giudice G, Rappuoli R, Rimmelzwaan GF, Osterhaus AD.

J Virol. 2011 Mar;85(6):2851-8. doi: 10.1128/JVI.01939-10. Epub 2011 Jan 5.

38.

Experimental pandemic (H1N1) 2009 virus infection of cats.

van den Brand JM, Stittelaar KJ, van Amerongen G, van de Bildt MW, Leijten LM, Kuiken T, Osterhaus AD.

Emerg Infect Dis. 2010 Nov;16(11):1745-7. doi: 10.3201/eid1611.100845.

39.

Pandemic 2009 H1N1 influenza virus causes diffuse alveolar damage in cynomolgus macaques.

Herfst S, van den Brand JM, Schrauwen EJ, de Wit E, Munster VJ, van Amerongen G, Linster M, Zaaraoui F, van Ijcken WF, Rimmelzwaan GF, Osterhaus AD, Fouchier RA, Andeweg AC, Kuiken T.

Vet Pathol. 2010 Nov;47(6):1040-7. doi: 10.1177/0300985810374836. Epub 2010 Jul 20.

PMID:
20647595
40.

Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype.

Munster VJ, Schrauwen EJ, de Wit E, van den Brand JM, Bestebroer TM, Herfst S, Rimmelzwaan GF, Osterhaus AD, Fouchier RA.

J Virol. 2010 Aug;84(16):7953-60. doi: 10.1128/JVI.00449-10. Epub 2010 Jun 2.

41.

A single immunization with CoVaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets.

Bodewes R, Kreijtz JH, van Amerongen G, Geelhoed-Mieras MM, Verburgh RJ, Heldens JG, Bedwell J, van den Brand JM, Kuiken T, van Baalen CA, Fouchier RA, Osterhaus AD, Rimmelzwaan GF.

J Virol. 2010 Aug;84(16):7943-52. doi: 10.1128/JVI.00549-10. Epub 2010 Jun 2.

42.

In vitro assessment of attachment pattern and replication efficiency of H5N1 influenza A viruses with altered receptor specificity.

Chutinimitkul S, van Riel D, Munster VJ, van den Brand JM, Rimmelzwaan GF, Kuiken T, Osterhaus AD, Fouchier RA, de Wit E.

J Virol. 2010 Jul;84(13):6825-33. doi: 10.1128/JVI.02737-09. Epub 2010 Apr 14.

43.

Severity of pneumonia due to new H1N1 influenza virus in ferrets is intermediate between that due to seasonal H1N1 virus and highly pathogenic avian influenza H5N1 virus.

van den Brand JM, Stittelaar KJ, van Amerongen G, Rimmelzwaan GF, Simon J, de Wit E, Munster V, Bestebroer T, Fouchier RA, Kuiken T, Osterhaus AD.

J Infect Dis. 2010 Apr 1;201(7):993-9. doi: 10.1086/651132.

PMID:
20187747
44.

Exacerbated innate host response to SARS-CoV in aged non-human primates.

Smits SL, de Lang A, van den Brand JM, Leijten LM, van IJcken WF, Eijkemans MJ, van Amerongen G, Kuiken T, Andeweg AC, Osterhaus AD, Haagmans BL.

PLoS Pathog. 2010 Feb 5;6(2):e1000756. doi: 10.1371/journal.ppat.1000756.

45.

MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization.

Kreijtz JH, Suezer Y, de Mutsert G, van Amerongen G, Schwantes A, van den Brand JM, Fouchier RA, Löwer J, Osterhaus AD, Sutter G, Rimmelzwaan GF.

PLoS One. 2009 Nov 12;4(11):e7790. doi: 10.1371/journal.pone.0007790.

46.

Preclinical evaluation of a modified vaccinia virus Ankara (MVA)-based vaccine against influenza A/H5N1 viruses.

Kreijtz JH, Suezer Y, de Mutsert G, van den Brand JM, van Amerongen G, Schnierle BS, Kuiken T, Fouchier RA, Löwer J, Osterhaus AD, Sutter G, Rimmelzwaan GF.

Vaccine. 2009 Oct 23;27(45):6296-9. doi: 10.1016/j.vaccine.2009.03.020.

PMID:
19840663
47.

Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets.

Munster VJ, de Wit E, van den Brand JM, Herfst S, Schrauwen EJ, Bestebroer TM, van de Vijver D, Boucher CA, Koopmans M, Rimmelzwaan GF, Kuiken T, Osterhaus AD, Fouchier RA.

Science. 2009 Jul 24;325(5939):481-3. doi: 10.1126/science.1177127. Epub 2009 Jul 2.

48.

Infection of mice with a human influenza A/H3N2 virus induces protective immunity against lethal infection with influenza A/H5N1 virus.

Kreijtz JH, Bodewes R, van den Brand JM, de Mutsert G, Baas C, van Amerongen G, Fouchier RA, Osterhaus AD, Rimmelzwaan GF.

Vaccine. 2009 Aug 6;27(36):4983-9. doi: 10.1016/j.vaccine.2009.05.079. Epub 2009 Jun 16.

PMID:
19538996
49.

Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus.

Bodewes R, Kreijtz JH, Baas C, Geelhoed-Mieras MM, de Mutsert G, van Amerongen G, van den Brand JM, Fouchier RA, Osterhaus AD, Rimmelzwaan GF.

PLoS One. 2009;4(5):e5538. doi: 10.1371/journal.pone.0005538. Epub 2009 May 14.

50.

Pathology and virus distribution in chickens naturally infected with highly pathogenic avian influenza A virus (H7N7) During the 2003 outbreak in The Netherlands.

van Riel D, van den Brand JM, Munster VJ, Besteboer TM, Fouchier RA, Osterhaus AD, Kuiken T.

Vet Pathol. 2009 Sep;46(5):971-6. doi: 10.1354/vp.08-VP-0215-K-BC. Epub 2009 May 9.

PMID:
19429981

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