Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

Endocytosis by macrophages: Interplay of macrophage scavenger receptor-1 and LDL receptor-related protein-1.

Béguin EP, Przeradzka MA, Janssen EFJ, Meems H, Sedek M, van der Zwaan C, Mertens K, van den Biggelaar M, Meijer AB, Mourik MJ.

Haematologica. 2019 Jun 27. pii: haematol.2018.210682. doi: 10.3324/haematol.2018.210682. [Epub ahead of print]

2.

Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells.

Schillemans M, Karampini E, Hoogendijk AJ, Wahedi M, van Alphen FPJ, van den Biggelaar M, Voorberg J, Bierings R.

J Proteomics. 2019 Aug 15;205:103417. doi: 10.1016/j.jprot.2019.103417. Epub 2019 Jun 13.

3.

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers TW, van den Biggelaar M, Voorberg J, Bierings R.

Haematologica. 2019 Jan 10. pii: haematol.2018.207787. doi: 10.3324/haematol.2018.207787. [Epub ahead of print]

4.

The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions.

Hsiao CC, Chu TY, Wu CJ, van den Biggelaar M, Pabst C, Hébert J, Kuijpers TW, Scicluna BP, I KY, Chen TC, Liebscher I, Hamann J, Lin HH.

Front Immunol. 2018 Dec 3;9:2830. doi: 10.3389/fimmu.2018.02830. eCollection 2018.

5.

Integrated proteomic analysis of tumor necrosis factor α and interleukin 1β-induced endothelial inflammation.

Béguin EP, van den Eshof BL, Hoogendijk AJ, Nota B, Mertens K, Meijer AB, van den Biggelaar M.

J Proteomics. 2019 Feb 10;192:89-101. doi: 10.1016/j.jprot.2018.08.011. Epub 2018 Aug 25.

PMID:
30153514
6.

The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.

Przeradzka MA, Meems H, van der Zwaan C, Ebberink EHTM, van den Biggelaar M, Mertens K, Meijer AB.

Biochem J. 2018 Sep 11;475(17):2819-2830. doi: 10.1042/BCJ20180431.

PMID:
30111575
7.

Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.

Salerno F, Engels S, van den Biggelaar M, van Alphen FPJ, Guislain A, Zhao W, Hodge DL, Bell SE, Medema JP, von Lindern M, Turner M, Young HA, Wolkers MC.

Nat Immunol. 2018 Aug;19(8):828-837. doi: 10.1038/s41590-018-0155-6. Epub 2018 Jul 9.

8.

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Schillemans M, Karampini E, van den Eshof BL, Gangaev A, Hofman M, van Breevoort D, Meems H, Janssen H, Mulder AA, Jost CR, Escher JC, Adam R, Carter T, Koster AJ, van den Biggelaar M, Voorberg J, Bierings R.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1549-1561. doi: 10.1161/ATVBAHA.117.310701. Epub 2018 Jun 7.

9.

Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity.

Cuadrado E, van den Biggelaar M, de Kivit S, Chen YY, Slot M, Doubal I, Meijer A, van Lier RAW, Borst J, Amsen D.

Immunity. 2018 May 15;48(5):1046-1059.e6. doi: 10.1016/j.immuni.2018.04.008. Epub 2018 May 8.

10.

Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages.

Heideveld E, Hampton-O'Neil LA, Cross SJ, van Alphen FPJ, van den Biggelaar M, Toye AM, van den Akker E.

Haematologica. 2018 Mar;103(3):395-405. doi: 10.3324/haematol.2017.179341. Epub 2017 Dec 28.

11.

Differences between Platelets Derived from Neonatal Cord Blood and Adult Peripheral Blood Assessed by Mass Spectrometry.

Stokhuijzen E, Koornneef JM, Nota B, van den Eshof BL, van Alphen FPJ, van den Biggelaar M, van der Zwaan C, Kuijk C, Mertens K, Fijnvandraat K, Meijer AB.

J Proteome Res. 2017 Oct 6;16(10):3567-3575. doi: 10.1021/acs.jproteome.7b00298. Epub 2017 Aug 30.

PMID:
28823163
12.

Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.

van den Eshof BL, Hoogendijk AJ, Simpson PJ, van Alphen FPJ, Zanivan S, Mertens K, Meijer AB, van den Biggelaar M.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1891-1902. doi: 10.1161/ATVBAHA.117.309926. Epub 2017 Aug 17.

PMID:
28818855
13.

Label-free Analysis of CD8+ T Cell Subset Proteomes Supports a Progressive Differentiation Model of Human-Virus-Specific T Cells.

van Aalderen MC, van den Biggelaar M, Remmerswaal EBM, van Alphen FPJ, Meijer AB, Ten Berge IJM, van Lier RAW.

Cell Rep. 2017 May 2;19(5):1068-1079. doi: 10.1016/j.celrep.2017.04.014.

14.

Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.

Hernandez-Fernaud JR, Ruengeler E, Casazza A, Neilson LJ, Pulleine E, Santi A, Ismail S, Lilla S, Dhayade S, MacPherson IR, McNeish I, Ennis D, Ali H, Kugeratski FG, Al Khamici H, van den Biggelaar M, van den Berghe PV, Cloix C, McDonald L, Millan D, Hoyle A, Kuchnio A, Carmeliet P, Valenzuela SM, Blyth K, Yin H, Mazzone M, Norman JC, Zanivan S.

Nat Commun. 2017 Feb 15;8:14206. doi: 10.1038/ncomms14206.

15.

Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.

Ebberink EH, Bouwens EA, Bloem E, Boon-Spijker M, van den Biggelaar M, Voorberg J, Meijer AB, Mertens K.

Haematologica. 2017 Apr;102(4):686-694. doi: 10.3324/haematol.2016.153163. Epub 2017 Jan 5.

16.

Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP).

De Nardis C, Lössl P, van den Biggelaar M, Madoori PK, Leloup N, Mertens K, Heck AJ, Gros P.

J Biol Chem. 2017 Jan 20;292(3):912-924. doi: 10.1074/jbc.M116.758862. Epub 2016 Dec 12.

17.

Hepatitis B Virus Protein X Induces Degradation of Talin-1.

van de Klundert MA, van den Biggelaar M, Kootstra NA, Zaaijer HL.

Viruses. 2016 Oct 19;8(10). pii: E281.

18.

Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components.

Gazendam RP, van de Geer A, van Hamme JL, Tool AT, van Rees DJ, Aarts CE, van den Biggelaar M, van Alphen F, Verkuijlen P, Meijer AB, Janssen H, Roos D, van den Berg TK, Kuijpers TW.

Haematologica. 2016 May;101(5):587-96. doi: 10.3324/haematol.2015.136630. Epub 2016 Jan 22.

19.

Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.

van den Biggelaar M, Madsen JJ, Faber JH, Zuurveld MG, van der Zwaan C, Olsen OH, Stennicke HR, Mertens K, Meijer AB.

J Biol Chem. 2015 Jul 3;290(27):16463-76. doi: 10.1074/jbc.M115.650911. Epub 2015 Apr 21.

20.

A novel chemical footprinting approach identifies critical lysine residues involved in the binding of receptor-associated protein to cluster II of LDL receptor-related protein.

Bloem E, Ebberink EH, van den Biggelaar M, van der Zwaan C, Mertens K, Meijer AB.

Biochem J. 2015 May 15;468(1):65-72. doi: 10.1042/BJ20140977.

PMID:
25728577
21.

The effect of shiga toxin on weibel-palade bodies in primary human endothelial cells.

Geelen J, van den Biggelaar M, Linssen P, van der Velden T, Mertens K, Monnens L.

Nephron Extra. 2014 Jul 8;4(2):101-7. doi: 10.1159/000363299. eCollection 2014 Jan.

22.

Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells.

van den Biggelaar M, Hernández-Fernaud JR, van den Eshof BL, Neilson LJ, Meijer AB, Mertens K, Zanivan S.

Blood. 2014 Mar 20;123(12):e22-36. doi: 10.1182/blood-2013-12-546036. Epub 2014 Feb 5.

23.

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis.

McGrath RT, van den Biggelaar M, Byrne B, O'Sullivan JM, Rawley O, O'Kennedy R, Voorberg J, Preston RJ, O'Donnell JS.

Blood. 2013 Dec 12;122(25):4107-10. doi: 10.1182/blood-2013-04-496851. Epub 2013 Oct 8.

24.

Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.

Bloem E, van den Biggelaar M, Wroblewska A, Voorberg J, Faber JH, Kjalke M, Stennicke HR, Mertens K, Meijer AB.

J Biol Chem. 2013 Oct 11;288(41):29670-9. doi: 10.1074/jbc.M113.473116. Epub 2013 Sep 5.

25.

A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX.

Bloem E, Meems H, van den Biggelaar M, Mertens K, Meijer AB.

J Biol Chem. 2013 Sep 6;288(36):26105-11. doi: 10.1074/jbc.M113.500884. Epub 2013 Jul 24.

26.

Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII.

Castro-Núñez L, Bloem E, Boon-Spijker MG, van der Zwaan C, van den Biggelaar M, Mertens K, Meijer AB.

J Biol Chem. 2013 Jan 4;288(1):393-400. doi: 10.1074/jbc.M112.400572. Epub 2012 Nov 20.

27.

Establishment of outgrowth endothelial cells from peripheral blood.

Martin-Ramirez J, Hofman M, van den Biggelaar M, Hebbel RP, Voorberg J.

Nat Protoc. 2012 Sep;7(9):1709-15. doi: 10.1038/nprot.2012.093. Epub 2012 Aug 23.

PMID:
22918388
28.

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.

Wroblewska A, van Haren SD, Herczenik E, Kaijen P, Ruminska A, Jin SY, Zheng XL, van den Biggelaar M, ten Brinke A, Meijer AB, Voorberg J.

Blood. 2012 May 31;119(22):5294-300. doi: 10.1182/blood-2011-11-391680. Epub 2012 Apr 12.

29.

Mass spectrometry-assisted study reveals that lysine residues 1967 and 1968 have opposite contribution to stability of activated factor VIII.

Bloem E, Meems H, van den Biggelaar M, van der Zwaan C, Mertens K, Meijer AB.

J Biol Chem. 2012 Feb 17;287(8):5775-83. doi: 10.1074/jbc.M111.308627. Epub 2012 Jan 3.

30.

Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.

Herczenik E, van Haren SD, Wroblewska A, Kaijen P, van den Biggelaar M, Meijer AB, Martinez-Pomares L, ten Brinke A, Voorberg J.

J Allergy Clin Immunol. 2012 Feb;129(2):501-9, 509.e1-5. doi: 10.1016/j.jaci.2011.08.029. Epub 2011 Oct 1.

PMID:
21962992
31.

Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.

Bouwens EA, Mourik MJ, van den Biggelaar M, Eikenboom JC, Voorberg J, Valentijn KM, Mertens K.

Blood. 2011 Nov 24;118(22):5947-56. doi: 10.1182/blood-2011-05-355354. Epub 2011 Sep 22.

32.

Storage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cells.

van den Biggelaar M, Bouwens EA, Voorberg J, Mertens K.

PLoS One. 2011;6(8):e24163. doi: 10.1371/journal.pone.0024163. Epub 2011 Aug 31.

33.

C1 domain residues Lys 2092 and Phe 2093 are of major importance for the endocytic uptake of coagulation factor VIII.

Meems H, van den Biggelaar M, Rondaij M, van der Zwaan C, Mertens K, Meijer AB.

Int J Biochem Cell Biol. 2011 Aug;43(8):1114-21. doi: 10.1016/j.biocel.2011.03.014. Epub 2011 Apr 8.

PMID:
21497669
34.

A single lysine of the two-lysine recognition motif of the D3 domain of receptor-associated protein is sufficient to mediate endocytosis by low-density lipoprotein receptor-related protein.

van den Biggelaar M, Sellink E, Klein Gebbinck JW, Mertens K, Meijer AB.

Int J Biochem Cell Biol. 2011 Mar;43(3):431-40. doi: 10.1016/j.biocel.2010.11.017. Epub 2010 Dec 7.

PMID:
21144910
35.

Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells.

van den Biggelaar M, Bouwens EA, Kootstra NA, Hebbel RP, Voorberg J, Mertens K.

Haematologica. 2009 May;94(5):670-8. doi: 10.3324/haematol.13427. Epub 2009 Mar 31.

36.

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles.

van den Biggelaar M, Meijer AB, Voorberg J, Mertens K.

Blood. 2009 Mar 26;113(13):3102-9. doi: 10.1182/blood-2008-05-159699. Epub 2008 Dec 16.

37.

Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.

van den Biggelaar M, Bierings R, Storm G, Voorberg J, Mertens K.

J Thromb Haemost. 2007 Nov;5(11):2235-42.

38.

Efficiency of von Willebrand factor-mediated targeting of interleukin-8 into Weibel-Palade bodies.

Bierings R, van den Biggelaar M, Kragt A, Mertens K, Voorberg J, van Mourik JA.

J Thromb Haemost. 2007 Dec;5(12):2512-9. Epub 2007 Sep 19.

Supplemental Content

Loading ...
Support Center