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Items: 1 to 50 of 643

1.

A LysM effector subverts chitin-triggered immunity to facilitate arbuscular mycorrhizal symbiosis.

Zeng T, Rodriguez-Moreno L, Mansurkhodzaev A, Wang P, van den Berg W, Gasciolli V, Cottaz S, Fort S, Thomma BPHJ, Bono JJ, Bisseling T, Limpens E.

New Phytol. 2019 Oct 9. doi: 10.1111/nph.16245. [Epub ahead of print]

PMID:
31596956
2.

Earlier discontinuation of TNF-α inhibitor therapy in female patients with inflammatory bowel disease is related to a greater risk of side effects.

Schultheiss JPD, Brand EC, Lamers E, van den Berg WCM, van Schaik FDM, Oldenburg B, Fidder HH.

Aliment Pharmacol Ther. 2019 Aug;50(4):386-396. doi: 10.1111/apt.15380. Epub 2019 Jul 16.

PMID:
31310690
3.

Increased WISP1 expression in human osteoarthritic articular cartilage is epigenetically regulated and decreases cartilage matrix production.

van den Bosch MHJ, Ramos YFM, den Hollander W, Bomer N, Nelissen RGHH, Bovée JVMG, van den Berg WB, van Lent PLEM, Blom AB, van der Kraan PM, Meulenbelt I.

Rheumatology (Oxford). 2019 Jun 1;58(6):1065-1074. doi: 10.1093/rheumatology/key426.

PMID:
30649473
4.

The level of synovial AXL expression determines the outcome of inflammatory arthritis, possibly depending on the upstream role of TGF-β1.

Waterborg CEJ, Broeren MGA, Blaney Davidson EN, Koenders MI, van Lent PLEM, van den Berg WB, van der Kraan PM, van de Loo FAJ.

Rheumatology (Oxford). 2019 Mar 1;58(3):536-546. doi: 10.1093/rheumatology/key337.

PMID:
30508140
5.

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation.

Broeren MGA, Di Ceglie I, Bennink MB, van Lent PLEM, van den Berg WB, Koenders MI, Blaney Davidson EN, van der Kraan PM, van de Loo FAJ.

PeerJ. 2018 May 30;6:e4771. doi: 10.7717/peerj.4771. eCollection 2018.

6.

Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models.

Waterborg CEJ, Beermann S, Broeren MGA, Bennink MB, Koenders MI, van Lent PLEM, van den Berg WB, van der Kraan PM, van de Loo FAJ.

Front Immunol. 2018 Apr 13;9:742. doi: 10.3389/fimmu.2018.00742. eCollection 2018.

7.

Imaging fibroblast activation protein to monitor therapeutic effects of neutralizing interleukin-22 in collagen-induced arthritis.

van der Geest T, Roeleveld DM, Walgreen B, Helsen MM, Nayak TK, Klein C, Hegen M, Storm G, Metselaar JM, van den Berg WB, van der Kraan PM, Laverman P, Boerman OC, Koenders MI.

Rheumatology (Oxford). 2018 Apr 1;57(4):737-747. doi: 10.1093/rheumatology/kex456.

PMID:
29361119
8.

Risks for infection of strawberry plants with an aerosolized inoculum of Xanthomonas fragariae.

van der Wolf JM, Evenhuis A, Kastelein P, Krijger MC, Funke VZ, van den Berg W, Moene AF.

Eur J Plant Pathol. 2018;152(3):711-722. doi: 10.1007/s10658-018-1513-9. Epub 2018 May 31.

9.

Alteration of the intestinal microbiome characterizes preclinical inflammatory arthritis in mice and its modulation attenuates established arthritis.

Rogier R, Evans-Marin H, Manasson J, van der Kraan PM, Walgreen B, Helsen MM, van den Bersselaar LA, van de Loo FA, van Lent PL, Abramson SB, van den Berg WB, Koenders MI, Scher JU, Abdollahi-Roodsaz S.

Sci Rep. 2017 Nov 15;7(1):15613. doi: 10.1038/s41598-017-15802-x.

10.

WISP1/CCN4 aggravates cartilage degeneration in experimental osteoarthritis.

van den Bosch MH, Blom AB, Kram V, Maeda A, Sikka S, Gabet Y, Kilts TM, van den Berg WB, van Lent PL, van der Kraan PM, Young MF.

Osteoarthritis Cartilage. 2017 Nov;25(11):1900-1911. doi: 10.1016/j.joca.2017.07.012. Epub 2017 Jul 19.

11.

Brief Report: Induction of Matrix Metalloproteinase Expression by Synovial Wnt Signaling and Association With Disease Progression in Early Symptomatic Osteoarthritis.

van den Bosch MH, Blom AB, van de Loo FA, Koenders MI, Lafeber FP, van den Berg WB, van der Kraan PM, van Lent PL.

Arthritis Rheumatol. 2017 Oct;69(10):1978-1983. doi: 10.1002/art.40206. Epub 2017 Aug 29.

12.

Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis.

Rogier R, Ederveen THA, Boekhorst J, Wopereis H, Scher JU, Manasson J, Frambach SJCM, Knol J, Garssen J, van der Kraan PM, Koenders MI, van den Berg WB, van Hijum SAFT, Abdollahi-Roodsaz S.

Microbiome. 2017 Jun 23;5(1):63. doi: 10.1186/s40168-017-0278-2.

13.

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis.

Roeleveld DM, Marijnissen RJ, Walgreen B, Helsen MM, van den Bersselaar L, van de Loo FA, van Lent PL, van der Kraan PM, van den Berg WB, Koenders MI.

PLoS One. 2017 Feb 3;12(2):e0171757. doi: 10.1371/journal.pone.0171757. eCollection 2017.

14.

A Dual Role of Upper Zone of Growth Plate and Cartilage Matrix-Associated Protein in Human and Mouse Osteoarthritic Cartilage: Inhibition of Aggrecanases and Promotion of Bone Turnover.

Stock M, Menges S, Eitzinger N, Geßlein M, Botschner R, Wormser L, Distler A, Schlötzer-Schrehardt U, Dietel K, Distler J, Beyer C, Gelse K, Engelke K, Koenders MI, van den Berg W, von der Mark K, Schett G.

Arthritis Rheumatol. 2017 Jun;69(6):1233-1245. doi: 10.1002/art.40042. Epub 2017 Apr 24.

15.

Interleukin-1 is not involved in synovial inflammation and cartilage destruction in collagenase-induced osteoarthritis.

van Dalen SC, Blom AB, Slöetjes AW, Helsen MM, Roth J, Vogl T, van de Loo FA, Koenders MI, van der Kraan PM, van den Berg WB, van den Bosch MH, van Lent PL.

Osteoarthritis Cartilage. 2017 Mar;25(3):385-396. doi: 10.1016/j.joca.2016.09.009. Epub 2016 Sep 18.

16.

Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane.

Broeren MG, de Vries M, Bennink MB, Arntz OJ, van Lent PL, van der Kraan PM, van den Berg WB, van den Hoogen FH, Koenders MI, van de Loo FA.

Arthritis Res Ther. 2016 Aug 12;18:186. doi: 10.1186/s13075-016-1083-1.

17.

Synovial macrophages promote TGF-β signaling and protect against influx of S100A8/S100A9-producing cells after intra-articular injections of oxidized low-density lipoproteins.

de Munter W, Geven EJ, Blom AB, Walgreen B, Helsen MM, Joosten LA, Roth J, Vogl T, van de Loo FA, Koenders MI, van den Berg WB, van der Kraan PM, van Lent PL.

Osteoarthritis Cartilage. 2017 Jan;25(1):118-127. doi: 10.1016/j.joca.2016.07.020. Epub 2016 Aug 8.

18.

Alarmin S100A9 Induces Proinflammatory and Catabolic Effects Predominantly in the M1 Macrophages of Human Osteoarthritic Synovium.

van den Bosch MH, Blom AB, Schelbergen RF, Koenders MI, van de Loo FA, van den Berg WB, Vogl T, Roth J, van der Kraan PM, van Lent PL.

J Rheumatol. 2016 Oct;43(10):1874-1884. Epub 2016 Aug 1.

PMID:
27481901
19.

Secukinumab for rheumatology: development and its potential place in therapy.

Koenders MI, van den Berg WB.

Drug Des Devel Ther. 2016 Jun 24;10:2069-80. doi: 10.2147/DDDT.S105263. eCollection 2016. Review.

20.

Low heme oxygenase-1 levels in patients with systemic sclerosis are associated with an altered Toll-like receptor response: another role for CXCL4?

van Bon L, Cossu M, Scharstuhl A, Pennings BW, Vonk MC, Vreman HJ, Lafyatis RL, van den Berg W, Wagener FA, Radstake TR.

Rheumatology (Oxford). 2016 Nov;55(11):2066-2073. Epub 2016 Jul 13.

PMID:
27411481
21.

Milk-Derived Nanoparticle Fraction Promotes the Formation of Small Osteoclasts But Reduces Bone Resorption.

Oliveira MC, Di Ceglie I, Arntz OJ, van den Berg WB, van den Hoogen FH, Ferreira AV, van Lent PL, van de Loo FA.

J Cell Physiol. 2017 Jan;232(1):225-33. doi: 10.1002/jcp.25414. Epub 2016 Jun 2.

PMID:
27138291
22.

Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts.

Uluçkan Ö, Jimenez M, Karbach S, Jeschke A, Graña O, Keller J, Busse B, Croxford AL, Finzel S, Koenders M, van den Berg W, Schinke T, Amling M, Waisman A, Schett G, Wagner EF.

Sci Transl Med. 2016 Mar 16;8(330):330ra37. doi: 10.1126/scitranslmed.aad8996. Epub 2016 Mar 16.

PMID:
27089206
23.

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

Wehmeyer C, Frank S, Beckmann D, Böttcher M, Cromme C, König U, Fennen M, Held A, Paruzel P, Hartmann C, Stratis A, Korb-Pap A, Kamradt T, Kramer I, van den Berg W, Kneissel M, Pap T, Dankbar B.

Sci Transl Med. 2016 Mar 16;8(330):330ra35. doi: 10.1126/scitranslmed.aac4351. Epub 2016 Mar 16.

PMID:
27089204
24.

Milk extracellular vesicles accelerate osteoblastogenesis but impair bone matrix formation.

Oliveira MC, Arntz OJ, Blaney Davidson EN, van Lent PL, Koenders MI, van der Kraan PM, van den Berg WB, Ferreira AV, van de Loo FA.

J Nutr Biochem. 2016 Apr;30:74-84. doi: 10.1016/j.jnutbio.2015.11.017. Epub 2015 Dec 28.

PMID:
27012623
25.

Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors.

van Caam A, Madej W, Thijssen E, Garcia de Vinuesa A, van den Berg W, Goumans MJ, Ten Dijke P, Blaney Davidson E, van der Kraan PM.

Osteoarthritis Cartilage. 2016 Jul;24(7):1235-45. doi: 10.1016/j.joca.2016.02.008. Epub 2016 Mar 12.

26.

Disease-Regulated Gene Therapy with Anti-Inflammatory Interleukin-10 Under the Control of the CXCL10 Promoter for the Treatment of Rheumatoid Arthritis.

Broeren MG, de Vries M, Bennink MB, Arntz OJ, Blom AB, Koenders MI, van Lent PL, van der Kraan PM, van den Berg WB, van de Loo FA.

Hum Gene Ther. 2016 Mar;27(3):244-54. doi: 10.1089/hum.2015.127. Epub 2016 Feb 16.

PMID:
26711533
27.

High LDL levels lead to increased synovial inflammation and accelerated ectopic bone formation during experimental osteoarthritis.

de Munter W, van den Bosch MH, Slöetjes AW, Croce KJ, Vogl T, Roth J, Koenders MI, van de Loo FA, van den Berg WB, van der Kraan PM, van Lent PL.

Osteoarthritis Cartilage. 2016 May;24(5):844-55. doi: 10.1016/j.joca.2015.11.016. Epub 2015 Dec 12.

28.

Wnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritis.

van den Bosch MH, Gleissl TA, Blom AB, van den Berg WB, van Lent PL, van der Kraan PM.

Rheumatology (Oxford). 2016 Sep;55(9):1536-47. doi: 10.1093/rheumatology/kev402. Epub 2015 Dec 14. Review.

PMID:
26667213
29.

Impaired Porphyromonas gingivalis-Induced Tumor Necrosis Factor Production by Dendritic Cells Typifies Patients With Rheumatoid Arthritis.

Santegoets KC, Wenink MH, Braga FA, Cossu M, Lamers-Karnebeek FB, van Riel PL, Sturm PD, van den Berg WB, Radstake TR.

Arthritis Rheumatol. 2016 Apr;68(4):795-804. doi: 10.1002/art.39514.

30.

Inflammation in osteoarthritis: changing views.

Berenbaum F, van den Berg WB.

Osteoarthritis Cartilage. 2015 Nov;23(11):1823-4. doi: 10.1016/j.joca.2015.09.012. No abstract available.

31.

The interferon type I signature is present in systemic sclerosis before overt fibrosis and might contribute to its pathogenesis through high BAFF gene expression and high collagen synthesis.

Brkic Z, van Bon L, Cossu M, van Helden-Meeuwsen CG, Vonk MC, Knaapen H, van den Berg W, Dalm VA, Van Daele PL, Severino A, Maria NI, Guillen S, Dik WA, Beretta L, Versnel MA, Radstake T.

Ann Rheum Dis. 2016 Aug;75(8):1567-73. doi: 10.1136/annrheumdis-2015-207392. Epub 2015 Sep 14.

PMID:
26371289
32.

Induction of Canonical Wnt Signaling by the Alarmins S100A8/A9 in Murine Knee Joints: Implications for Osteoarthritis.

van den Bosch MH, Blom AB, Schelbergen RF, Vogl T, Roth JP, Slöetjes AW, van den Berg WB, van der Kraan PM, van Lent PL.

Arthritis Rheumatol. 2016 Jan;68(1):152-63. doi: 10.1002/art.39420.

33.

Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis.

Blüml S, Sahin E, Saferding V, Goncalves-Alves E, Hainzl E, Niederreiter B, Hladik A, Lohmeyer T, Brunner JS, Bonelli M, Koenders MI, van den Berg WB, Superti-Furga G, Smolen JS, Schabbauer G, Redlich K.

Arthritis Res Ther. 2015 Aug 26;17:230. doi: 10.1186/s13075-015-0742-y.

34.

High systemic levels of low-density lipoprotein cholesterol: fuel to the flames in inflammatory osteoarthritis?

de Munter W, van der Kraan PM, van den Berg WB, van Lent PL.

Rheumatology (Oxford). 2016 Jan;55(1):16-24. doi: 10.1093/rheumatology/kev270. Epub 2015 Jul 31. Review.

PMID:
26231344
35.
36.

Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models.

Arntz OJ, Pieters BC, Oliveira MC, Broeren MG, Bennink MB, de Vries M, van Lent PL, Koenders MI, van den Berg WB, van der Kraan PM, van de Loo FA.

Mol Nutr Food Res. 2015 Sep;59(9):1701-12. doi: 10.1002/mnfr.201500222. Epub 2015 Jul 1.

PMID:
26047123
37.

Induction of Canonical Wnt Signaling by Synovial Overexpression of Selected Wnts Leads to Protease Activity and Early Osteoarthritis-Like Cartilage Damage.

van den Bosch MH, Blom AB, Sloetjes AW, Koenders MI, van de Loo FA, van den Berg WB, van Lent PL, van der Kraan PM.

Am J Pathol. 2015 Jul;185(7):1970-80. doi: 10.1016/j.ajpath.2015.03.013. Epub 2015 May 12.

PMID:
25976248
38.

Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.

Schelbergen RF, Geven EJ, van den Bosch MH, Eriksson H, Leanderson T, Vogl T, Roth J, van de Loo FA, Koenders MI, van der Kraan PM, van den Berg WB, Blom AB, van Lent PL.

Ann Rheum Dis. 2015 Dec;74(12):2254-8. doi: 10.1136/annrheumdis-2014-206517. Epub 2015 May 12.

PMID:
25969431
39.

Correction: Improving Men's Participation in Preventing Mother-to-Child Transmission of HIV as a Maternal, Neonatal, and Child Health Priority in South Africa.

van den Berg W, Brittain K, Mercer G, Peacock D, Stinson K, Janson H, Dubula V.

PLoS Med. 2015 May 11;12(5):e1001836. doi: 10.1371/journal.pmed.1001836. eCollection 2015 May. No abstract available.

40.

The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis.

Vermeij EA, Koenders MI, Bennink MB, Crowe LA, Maurizi L, Vallée JP, Hofmann H, van den Berg WB, van Lent PL, van de Loo FA.

PLoS One. 2015 May 8;10(5):e0126687. doi: 10.1371/journal.pone.0126687. eCollection 2015.

41.

Improving men's participation in preventing mother-to-child transmission of HIV as a maternal, neonatal, and child health priority in South Africa.

van den Berg W, Brittain K, Mercer G, Peacock D, Stinson K, Janson H, Dubula V.

PLoS Med. 2015 Apr 7;12(4):e1001811. doi: 10.1371/journal.pmed.1001811. eCollection 2015 Apr. No abstract available. Erratum in: PLoS Med. 2015 May;12(5):e1001836.

42.

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β.

Pieters BC, Arntz OJ, Bennink MB, Broeren MG, van Caam AP, Koenders MI, van Lent PL, van den Berg WB, de Vries M, van der Kraan PM, van de Loo FA.

PLoS One. 2015 Mar 30;10(3):e0121123. doi: 10.1371/journal.pone.0121123. eCollection 2015.

43.

Ligation-independent cloning for plant research.

Wendrich JR, Liao CY, van den Berg WA, De Rybel B, Weijers D.

Methods Mol Biol. 2015;1284:421-31. doi: 10.1007/978-1-4939-2444-8_21.

PMID:
25757785
44.

Novel therapeutic targets in rheumatoid arthritis.

Koenders MI, van den Berg WB.

Trends Pharmacol Sci. 2015 Apr;36(4):189-95. doi: 10.1016/j.tips.2015.02.001. Epub 2015 Feb 27. Review.

PMID:
25732812
45.

The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1.

van Caam A, Blaney Davidson E, Garcia de Vinuesa A, van Geffen E, van den Berg W, Goumans MJ, ten Dijke P, van der Kraan P.

Osteoarthritis Cartilage. 2015 Jun;23(6):985-95. doi: 10.1016/j.joca.2015.02.007. Epub 2015 Feb 12.

46.

Fragile X mice have robust mGluR5-dependent alterations of social behaviour in the Automated Tube Test.

de Esch CE, van den Berg WE, Buijsen RA, Jaafar IA, Nieuwenhuizen-Bakker IM, Gasparini F, Kushner SA, Willemsen R.

Neurobiol Dis. 2015 Mar;75:31-9. doi: 10.1016/j.nbd.2014.12.021. Epub 2015 Jan 3.

PMID:
25562659
47.

Survival and biodistribution of xenogenic adipose mesenchymal stem cells is not affected by the degree of inflammation in arthritis.

Toupet K, Maumus M, Luz-Crawford P, Lombardo E, Lopez-Belmonte J, van Lent P, Garin MI, van den Berg W, Dalemans W, Jorgensen C, Noël D.

PLoS One. 2015 Jan 5;10(1):e0114962. doi: 10.1371/journal.pone.0114962. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0120406.

48.

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

Blaney Davidson EN, van Caam AP, Vitters EL, Bennink MB, Thijssen E, van den Berg WB, Koenders MI, van Lent PL, van de Loo FA, van der Kraan PM.

Osteoarthritis Cartilage. 2015 Mar;23(3):478-86. doi: 10.1016/j.joca.2014.12.005. Epub 2014 Dec 18.

49.

Sex-specific mechanism of social hierarchy in mice.

van den Berg WE, Lamballais S, Kushner SA.

Neuropsychopharmacology. 2015 May;40(6):1364-72. doi: 10.1038/npp.2014.319. Epub 2014 Dec 3.

50.

Fc gamma receptor IIb on GM-CSF macrophages controls immune complex mediated inhibition of inflammatory signals.

Santegoets KC, Wenink MH, van den Berg WB, Radstake TR.

PLoS One. 2014 Oct 23;9(10):e110966. doi: 10.1371/journal.pone.0110966. eCollection 2014.

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