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Items: 1 to 50 of 163

1.

Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair.

Aarts CEM, Hiemstra IH, Béguin EP, Hoogendijk AJ, Bouchmal S, van Houdt M, Tool ATJ, Mul E, Jansen MH, Janssen H, van Alphen FPJ, de Boer JP, Zuur CL, Meijer AB, van den Berg TK, Kuijpers TW.

Blood Adv. 2019 Nov 26;3(22):3562-3574. doi: 10.1182/bloodadvances.2019031609.

PMID:
31738831
2.

IgA mediated killing of tumor cells by neutrophils is enhanced by CD47-SIRPα checkpoint inhibition.

Treffers LW, Ten Broeke T, Rösner T, Jansen JHM, van Houdt M, Kahle S, Schornagel K, Verkuijlen PJJH, Prins JM, Franke K, Kuijpers TW, van den Berg TK, Valerius T, Leusen JHW, Matlung HL.

Cancer Immunol Res. 2019 Nov 5. pii: canimm.0144.2019. doi: 10.1158/2326-6066.CIR-19-0144. [Epub ahead of print]

PMID:
31690649
3.

Tissue-specific expression of IgG receptors by human macrophages ex vivo.

Bruggeman CW, Houtzager J, Dierdorp B, Kers J, Pals ST, Lutter R, van Gulik T, den Haan JMM, van den Berg TK, van Bruggen R, Kuijpers TW.

PLoS One. 2019 Oct 15;14(10):e0223264. doi: 10.1371/journal.pone.0223264. eCollection 2019.

4.

Neutrophils as Suppressors of T Cell Proliferation: Does Age Matter?

Aarts CEM, Hiemstra IH, Tool ATJ, van den Berg TK, Mul E, van Bruggen R, Kuijpers TW.

Front Immunol. 2019 Sep 11;10:2144. doi: 10.3389/fimmu.2019.02144. eCollection 2019.

5.

Neutrophils acquire antigen-presenting cell features after phagocytosis of IgG-opsonized erythrocytes.

Meinderts SM, Baker G, van Wijk S, Beuger BM, Geissler J, Jansen MH, Saris A, Ten Brinke A, Kuijpers TW, van den Berg TK, van Bruggen R.

Blood Adv. 2019 Jun 11;3(11):1761-1773. doi: 10.1182/bloodadvances.2018028753.

6.

Identification of genetic biomarkers for alloimmunization in sickle cell disease.

Meinderts SM, Gerritsma JJ, Sins JWR, de Boer M, van Leeuwen K, Biemond BJ, Rijneveld AW, Kerkhoffs JH, Habibi A, van Bruggen R, Kuijpers TW, van der Schoot E, Pirenne F, Fijnvandraat K, Tanck MW, van den Berg TK.

Br J Haematol. 2019 Sep;186(6):887-899. doi: 10.1111/bjh.15998. Epub 2019 Jun 5.

PMID:
31168801
7.

Extensive Ethnic Variation and Linkage Disequilibrium at the FCGR2/3 Locus: Different Genetic Associations Revealed in Kawasaki Disease.

Nagelkerke SQ, Tacke CE, Breunis WB, Tanck MWT, Geissler J, Png E, Hoang LT, van der Heijden J, Naim ANM, Yeung RSM, Levin ML, Wright VJ, Burgner DP, Ponsonby AL, Ellis JA, Cimaz R, Shimizu C, Burns JC, Fijnvandraat K, van der Schoot CE, van den Berg TK, de Boer M, Davila S, Hibberd ML, Kuijpers TW; International Kawasaki Disease Genetics Consortium.

Front Immunol. 2019 Mar 21;10:185. doi: 10.3389/fimmu.2019.00185. eCollection 2019.

8.

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.

Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN.

Nat Med. 2019 Apr;25(4):612-619. doi: 10.1038/s41591-019-0356-z. Epub 2019 Mar 4.

PMID:
30833751
9.

FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils.

Treffers LW, van Houdt M, Bruggeman CW, Heineke MH, Zhao XW, van der Heijden J, Nagelkerke SQ, Verkuijlen PJJH, Geissler J, Lissenberg-Thunnissen S, Valerius T, Peipp M, Franke K, van Bruggen R, Kuijpers TW, van Egmond M, Vidarsson G, Matlung HL, van den Berg TK.

Front Immunol. 2019 Jan 30;9:3124. doi: 10.3389/fimmu.2018.03124. eCollection 2018.

10.

Myeloid immune-checkpoint inhibition enters the clinical stage.

van den Berg TK, Valerius T.

Nat Rev Clin Oncol. 2019 May;16(5):275-276. doi: 10.1038/s41571-018-0155-3. No abstract available.

PMID:
30573788
11.

IgG Glyco-Engineering to Improve IVIg Potency.

Bruggeman CW, Dekkers G, Visser R, Goes NWM, van den Berg TK, Rispens T, Vidarsson G, Kuijpers TW.

Front Immunol. 2018 Oct 23;9:2442. doi: 10.3389/fimmu.2018.02442. eCollection 2018.

12.

Immune Effector Functions of Human IgG2 Antibodies against EGFR.

Rösner T, Kahle S, Montenegro F, Matlung HL, Jansen JHM, Evers M, Beurskens F, Leusen JHW, van den Berg TK, Valerius T.

Mol Cancer Ther. 2019 Jan;18(1):75-88. doi: 10.1158/1535-7163.MCT-18-0341. Epub 2018 Oct 3.

PMID:
30282813
13.

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils.

Grassi L, Pourfarzad F, Ullrich S, Merkel A, Were F, Carrillo-de-Santa-Pau E, Yi G, Hiemstra IH, Tool ATJ, Mul E, Perner J, Janssen-Megens E, Berentsen K, Kerstens H, Habibi E, Gut M, Yaspo ML, Linser M, Lowy E, Datta A, Clarke L, Flicek P, Vingron M, Roos D, van den Berg TK, Heath S, Rico D, Frontini M, Kostadima M, Gut I, Valencia A, Ouwehand WH, Stunnenberg HG, Martens JHA, Kuijpers TW.

Cell Rep. 2018 Sep 4;24(10):2784-2794. doi: 10.1016/j.celrep.2018.08.018.

14.

Inherited p40phox deficiency differs from classic chronic granulomatous disease.

van de Geer A, Nieto-Patlán A, Kuhns DB, Tool AT, Arias AA, Bouaziz M, de Boer M, Franco JL, Gazendam RP, van Hamme JL, van Houdt M, van Leeuwen K, Verkuijlen PJ, van den Berg TK, Alzate JF, Arango-Franco CA, Batura V, Bernasconi AR, Boardman B, Booth C, Burns SO, Cabarcas F, Bensussan NC, Charbit-Henrion F, Corveleyn A, Deswarte C, Azcoiti ME, Foell D, Gallin JI, Garcés C, Guedes M, Hinze CH, Holland SM, Hughes SM, Ibañez P, Malech HL, Meyts I, Moncada-Velez M, Moriya K, Neves E, Oleastro M, Perez L, Rattina V, Oleaga-Quintas C, Warner N, Muise AM, López JS, Trindade E, Vasconcelos J, Vermeire S, Wittkowski H, Worth A, Abel L, Dinauer MC, Arkwright PD, Roos D, Casanova JL, Kuijpers TW, Bustamante J.

J Clin Invest. 2018 Aug 31;128(9):3957-3975. doi: 10.1172/JCI97116. Epub 2018 Aug 6.

15.

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

Matlung HL, Babes L, Zhao XW, van Houdt M, Treffers LW, van Rees DJ, Franke K, Schornagel K, Verkuijlen P, Janssen H, Halonen P, Lieftink C, Beijersbergen RL, Leusen JHW, Boelens JJ, Kuhnle I, van der Werff Ten Bosch J, Seeger K, Rutella S, Pagliara D, Matozaki T, Suzuki E, Menke-van der Houven van Oordt CW, van Bruggen R, Roos D, van Lier RAW, Kuijpers TW, Kubes P, van den Berg TK.

Cell Rep. 2018 Jun 26;23(13):3946-3959.e6. doi: 10.1016/j.celrep.2018.05.082.

16.

Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-γ receptors.

Nagelkerke SQ, Bruggeman CW, den Haan JMM, Mul EPJ, van den Berg TK, van Bruggen R, Kuijpers TW.

Blood Adv. 2018 Apr 24;2(8):941-953. doi: 10.1182/bloodadvances.2017015008.

17.

A comprehensive proteomics study on platelet concentrates: Platelet proteome, storage time and Mirasol pathogen reduction technology.

Salunkhe V, De Cuyper IM, Papadopoulos P, van der Meer PF, Daal BB, Villa-Fajardo M, de Korte D, van den Berg TK, Gutiérrez L.

Platelets. 2019;30(3):368-379. doi: 10.1080/09537104.2018.1447658. Epub 2018 Mar 19.

PMID:
29553857
18.

Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging.

Klei TRL, de Back DZ, Asif PJ, Verkuijlen PJJH, Veldthuis M, Ligthart PC, Berghuis J, Clifford E, Beuger BM, van den Berg TK, van Zwieten R, El Nemer W, van Bruggen R.

Blood Adv. 2018 Jan 3;2(1):14-24. doi: 10.1182/bloodadvances.2017013094. eCollection 2018 Jan 9.

19.

A false-carrier state for the c.579G>A mutation in the NCF1 gene in Ashkenazi Jews.

De Boer M, Gavrieli R, van Leeuwen K, Wolf HR, Dushnitzki M, Bar-Yosef Y, Bar-Ziv A, Behar D, Lipitz S, Miller TE, Tool ATJ, Kuijpers TW, van den Berg TK, Wolach B, Roos D, Pras E.

J Med Genet. 2018 Mar;55(3):166-172. doi: 10.1136/jmedgenet-2017-105022. Epub 2018 Jan 13.

PMID:
29331982
20.

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.

Verbij FC, Sorvillo N, Kaijen PHP, Hrdinova J, Peyron I, Fijnheer R, Ten Brinke A, Meijer AB, van Alphen FPJ, van den Berg TK, Graversen JJH, Moestrup SK, Voorberg J.

Blood Adv. 2017 Jan 16;1(5):293-305. doi: 10.1182/bloodadvances.2016001321. eCollection 2017 Jan 24.

21.

Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells.

Meinderts SM, Oldenborg PA, Beuger BM, Klei TRL, Johansson J, Kuijpers TW, Matozaki T, Huisman EJ, de Haas M, van den Berg TK, van Bruggen R.

Blood Adv. 2017 May 26;1(14):875-886. doi: 10.1182/bloodadvances.2017004671. eCollection 2017 Jun 13.

22.

Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor α.

van der Spek AH, Surovtseva OV, Aan S, Tool ATJ, van de Geer A, Demir K, van Gucht ALM, van Trotsenburg ASP, van den Berg TK, Fliers E, Boelen A.

Endocr Connect. 2017 Nov;6(8):731-740. doi: 10.1530/EC-17-0213.

23.

Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells.

Treffers LW, Zhao XW, van der Heijden J, Nagelkerke SQ, van Rees DJ, Gonzalez P, Geissler J, Verkuijlen P, van Houdt M, de Boer M, Kuijpers TW, van den Berg TK, Matlung HL.

Eur J Immunol. 2018 Feb;48(2):344-354. doi: 10.1002/eji.201747215. Epub 2017 Nov 2.

24.

Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease.

Meinderts SM, Sins JWR, Fijnvandraat K, Nagelkerke SQ, Geissler J, Tanck MW, Bruggeman C, Biemond BJ, Rijneveld AW, Kerkhoffs JH, Pakdaman S, Habibi A, van Bruggen R, Kuijpers TW, Pirenne F, van den Berg TK.

Blood. 2017 Nov 9;130(19):2121-2130. doi: 10.1182/blood-2017-05-784876. Epub 2017 Sep 12.

PMID:
28899854
25.

Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities.

Dekkers G, Treffers L, Plomp R, Bentlage AEH, de Boer M, Koeleman CAM, Lissenberg-Thunnissen SN, Visser R, Brouwer M, Mok JY, Matlung H, van den Berg TK, van Esch WJE, Kuijpers TW, Wouters D, Rispens T, Wuhrer M, Vidarsson G.

Front Immunol. 2017 Aug 2;8:877. doi: 10.3389/fimmu.2017.00877. eCollection 2017.

26.

The Lung is a Host Defense Niche for Immediate Neutrophil-Mediated Vascular Protection.

Yipp BG, Kim JH, Lima R, Zbytnuik LD, Petri B, Swanlund N, Ho M, Szeto VG, Tak T, Koenderman L, Pickkers P, Tool ATJ, Kuijpers TW, van den Berg TK, Looney MR, Krummel MF, Kubes P.

Sci Immunol. 2017 Apr 28;2(10). pii: eaam8929. doi: 10.1126/sciimmunol.aam8929.

27.

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

de Boer M, van Leeuwen K, Geissler J, van Alphen F, de Vries E, van der Kuip M, Terheggen SWJ, Janssen H, van den Berg TK, Meijer AB, Roos D, Kuijpers TW.

Hum Mutat. 2017 Oct;38(10):1402-1411. doi: 10.1002/humu.23271. Epub 2017 Jun 15.

PMID:
28585318
28.

Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile.

Bruggeman CW, Dekkers G, Bentlage AEH, Treffers LW, Nagelkerke SQ, Lissenberg-Thunnissen S, Koeleman CAM, Wuhrer M, van den Berg TK, Rispens T, Vidarsson G, Kuijpers TW.

J Immunol. 2017 Jul 1;199(1):204-211. doi: 10.4049/jimmunol.1700116. Epub 2017 May 31.

29.

The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.

Matlung HL, Szilagyi K, Barclay NA, van den Berg TK.

Immunol Rev. 2017 Mar;276(1):145-164. doi: 10.1111/imr.12527. Review.

PMID:
28258703
30.

From the Cradle to the Grave: The Role of Macrophages in Erythropoiesis and Erythrophagocytosis.

Klei TR, Meinderts SM, van den Berg TK, van Bruggen R.

Front Immunol. 2017 Feb 2;8:73. doi: 10.3389/fimmu.2017.00073. eCollection 2017. Review.

31.

Characterization of buffy coat-derived granulocytes for clinical use: a comparison with granulocyte colony-stimulating factor/dexamethasone-pretreated donor-derived products.

van de Geer A, Gazendam RP, Tool AT, van Hamme JL, de Korte D, van den Berg TK, Zeerleder SS, Kuijpers TW.

Vox Sang. 2017 Feb;112(2):173-182. doi: 10.1111/vox.12481. Epub 2017 Jan 25.

PMID:
28120426
32.

Dexamethasone promotes granulocyte mobilization by prolonging the half-life of granulocyte-colony-stimulating factor in healthy donors for granulocyte transfusions.

Hiemstra IH, van Hamme JL, Janssen MH, van den Berg TK, Kuijpers TW.

Transfusion. 2017 Mar;57(3):674-684. doi: 10.1111/trf.13941. Epub 2016 Dec 28.

PMID:
28032635
33.

Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency.

Kuijpers TW, Tool ATJ, van der Bijl I, de Boer M, van Houdt M, de Cuyper IM, Roos D, van Alphen F, van Leeuwen K, Cambridge EL, Arends MJ, Dougan G, Clare S, Ramirez-Solis R, Pals ST, Adams DJ, Meijer AB, van den Berg TK.

J Allergy Clin Immunol. 2017 Jul;140(1):273-277.e10. doi: 10.1016/j.jaci.2016.09.061. Epub 2016 Dec 10. No abstract available.

PMID:
27965109
34.

GATA1-Deficient Dendritic Cells Display Impaired CCL21-Dependent Migration toward Lymph Nodes Due to Reduced Levels of Polysialic Acid.

Scheenstra MR, De Cuyper IM, Branco-Madeira F, de Bleser P, Kool M, Meinders M, Hoogenboezem M, Mul E, Wolkers MC, Salerno F, Nota B, Saeys Y, Klarenbeek S, van IJcken WF, Hammad H, Philipsen S, van den Berg TK, Kuijpers TW, Lambrecht BN, Gutiérrez L.

J Immunol. 2016 Dec 1;197(11):4312-4324. Epub 2016 Nov 4.

35.

Immune checkpoint blockade: Which switches to hit and how much?

Matlung HL, Szilagyi K, Kuijpers TW, van Lier RAW, van den Berg TK.

Immunol Lett. 2016 Dec;180:73-74. doi: 10.1016/j.imlet.2016.08.014. Epub 2016 Sep 20. No abstract available.

PMID:
27662791
36.

Neutrophils in cancer.

Treffers LW, Hiemstra IH, Kuijpers TW, van den Berg TK, Matlung HL.

Immunol Rev. 2016 Sep;273(1):312-28. doi: 10.1111/imr.12444. Review.

PMID:
27558343
37.

How neutrophils kill fungi.

Gazendam RP, van de Geer A, Roos D, van den Berg TK, Kuijpers TW.

Immunol Rev. 2016 Sep;273(1):299-311. doi: 10.1111/imr.12454. Review.

PMID:
27558342
38.

Proinflammatory cytokine response toward fungi but not bacteria in chronic granulomatous disease.

Gazendam RP, van de Geer A, van Hamme JL, Helgers L, Rohr J, Chrabieh M, Picard C, Roos D, van den Berg JM, van den Berg TK, Kuijpers TW.

J Allergy Clin Immunol. 2016 Sep;138(3):928-930.e4. doi: 10.1016/j.jaci.2016.03.035. Epub 2016 May 5. No abstract available.

PMID:
27283382
39.

Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment.

Meinders M, Hoogenboezem M, Scheenstra MR, De Cuyper IM, Papadopoulos P, Németh T, Mócsai A, van den Berg TK, Kuijpers TW, Gutiérrez L.

PLoS One. 2016 May 6;11(5):e0154342. doi: 10.1371/journal.pone.0154342. eCollection 2016.

40.

Immunoreceptors on neutrophils.

van Rees DJ, Szilagyi K, Kuijpers TW, Matlung HL, van den Berg TK.

Semin Immunol. 2016 Apr;28(2):94-108. doi: 10.1016/j.smim.2016.02.004. Epub 2016 Mar 11. Review.

PMID:
26976825
41.

Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components.

Gazendam RP, van de Geer A, van Hamme JL, Tool AT, van Rees DJ, Aarts CE, van den Biggelaar M, van Alphen F, Verkuijlen P, Meijer AB, Janssen H, Roos D, van den Berg TK, Kuijpers TW.

Haematologica. 2016 May;101(5):587-96. doi: 10.3324/haematol.2015.136630. Epub 2016 Jan 22.

42.

Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects.

Gazendam RP, van Hamme JL, Tool AT, Hoogenboezem M, van den Berg JM, Prins JM, Vitkov L, van de Veerdonk FL, van den Berg TK, Roos D, Kuijpers TW.

J Immunol. 2016 Feb 1;196(3):1272-83. doi: 10.4049/jimmunol.1501811. Epub 2015 Dec 30.

43.

Loss of CD47 Makes Dendritic Cells See Red.

van den Berg TK, van Bruggen R.

Immunity. 2015 Oct 20;43(4):622-4. doi: 10.1016/j.immuni.2015.09.008.

44.

Characterization of hematopoietic GATA transcription factor expression in mouse and human dendritic cells.

Scheenstra MR, Salunkhe V, De Cuyper IM, Hoogenboezem M, Li E, Kuijpers TW, van den Berg TK, Gutiérrez L.

Blood Cells Mol Dis. 2015 Dec;55(4):293-303. doi: 10.1016/j.bcmd.2015.07.006. Epub 2015 Jul 14.

PMID:
26460250
45.

Intrinsic defects in erythroid cells from familial hemophagocytic lymphohistiocytosis type 5 patients identify a role for STXBP2/Munc18-2 in erythropoiesis and phospholipid scrambling.

Kostova EB, Beuger BM, Veldthuis M, van der Werff Ten Bosch J, Kühnle I, van den Akker E, van den Berg TK, van Zwieten R, van Bruggen R.

Exp Hematol. 2015 Dec;43(12):1072-1076.e2. doi: 10.1016/j.exphem.2015.08.007. Epub 2015 Aug 28.

PMID:
26320718
46.

Study on the protective effect of the KIR3DL1 gene in ankylosing spondylitis.

Vendelbosch S, Heslinga SC, John M, van Leeuwen K, Geissler J, de Boer M, Tanck MW, van den Berg TK, Crusius JB, van der Horst-Bruinsma IE, Kuijpers TW.

Arthritis Rheumatol. 2015 Nov;67(11):2957-65. doi: 10.1002/art.39288.

47.

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency.

Szilagyi K, Gazendam RP, van Hamme JL, Tool AT, van Houdt M, Vos WA, Verkuijlen P, Janssen H, Belot A, Juillard L, Förster-Waldl E, Boztug K, Kraal G, de Winther MP, Kuijpers TW, van den Berg TK.

J Allergy Clin Immunol. 2015 Nov;136(5):1404-7.e1-10. doi: 10.1016/j.jaci.2015.06.016. Epub 2015 Jul 30. No abstract available.

PMID:
26233929
48.

Trichuris suis induces human non-classical patrolling monocytes via the mannose receptor and PKC: implications for multiple sclerosis.

Kooij G, Braster R, Koning JJ, Laan LC, van Vliet SJ, Los T, Eveleens AM, van der Pol SM, Förster-Waldl E, Boztug K, Belot A, Szilagyi K, van den Berg TK, van Buul JD, van Egmond M, de Vries HE, Cummings RD, Dijkstra CD, van Die I.

Acta Neuropathol Commun. 2015 Jul 25;3:45. doi: 10.1186/s40478-015-0223-1.

49.

Nonallelic homologous recombination of the FCGR2/3 locus results in copy number variation and novel chimeric FCGR2 genes with aberrant functional expression.

Nagelkerke SQ, Tacke CE, Breunis WB, Geissler J, Sins JW, Appelhof B, van den Berg TK, de Boer M, Kuijpers TW.

Genes Immun. 2015 Sep;16(6):422-9. doi: 10.1038/gene.2015.25. Epub 2015 Jul 2.

PMID:
26133275
50.

Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.

Alvarez-Zarate J, Matlung HL, Matozaki T, Kuijpers TW, Maridonneau-Parini I, van den Berg TK.

PLoS One. 2015 Jun 9;10(6):e0127178. doi: 10.1371/journal.pone.0127178. eCollection 2015.

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