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Items: 1 to 50 of 142

1.

Estradiol accelerates the effects of fluoxetine on serotonin 1A receptor signaling.

Li Q, Sullivan NR, McAllister CE, Van de Kar LD, Muma NA.

Psychoneuroendocrinology. 2013 Jul;38(7):1145-57. doi: 10.1016/j.psyneuen.2012.11.005. Epub 2012 Dec 5.

2.

Estradiol induces partial desensitization of serotonin 1A receptor signaling in the paraventricular nucleus of the hypothalamus and alters expression and interaction of RGSZ1 and Gαz.

Creech RD, Li Q, Carrasco GA, Van de Kar LD, Muma NA.

Neuropharmacology. 2012 Apr;62(5-6):2040-9. doi: 10.1016/j.neuropharm.2012.01.001. Epub 2012 Jan 10.

3.

Cerebrospinal fluid oxytocin, life history of aggression, and personality disorder.

Lee R, Ferris C, Van de Kar LD, Coccaro EF.

Psychoneuroendocrinology. 2009 Nov;34(10):1567-73. doi: 10.1016/j.psyneuen.2009.06.002. Epub 2009 Jul 3.

PMID:
19577376
4.

5-HT1A receptors mediate (+)8-OH-DPAT-stimulation of extracellular signal-regulated kinase (MAP kinase) in vivo in rat hypothalamus: time dependence and regional differences.

Crane JW, Shimizu K, Carrasco GA, Garcia F, Jia C, Sullivan NR, D'Souza DN, Zhang Y, Van de Kar LD, Muma NA, Battaglia G.

Brain Res. 2007 Dec 5;1183:51-9. Epub 2007 Sep 29.

PMID:
17976547
5.

Chronic olanzapine activates the Stat3 signal transduction pathway and alters expression of components of the 5-HT2A receptor signaling system in rat frontal cortex.

Muma NA, Singh RK, Vercillo MS, D'Souza DN, Zemaitaitis B, Garcia F, Damjanoska KJ, Zhang Y, Battaglia G, Van de Kar LD.

Neuropharmacology. 2007 Sep;53(4):552-62. Epub 2007 Jul 1.

6.

Single exposure to a serotonin 1A receptor agonist, (+)8-hydroxy-2-(di-n-propylamino)-tetralin, produces a prolonged heterologous desensitization of serotonin 2A receptors in neuroendocrine neurons in vivo.

Carrasco GA, Van de Kar LD, Jia C, Xu H, Chen Z, Chadda R, Garcia F, Muma NA, Battaglia G.

J Pharmacol Exp Ther. 2007 Mar;320(3):1078-86. Epub 2006 Dec 11.

PMID:
17159160
7.

Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon.

Carrasco GA, Van de Kar LD, Sullivan NR, Landry M, Garcia F, Muma NA, Battaglia G.

Neuroscience. 2006 Nov 17;143(1):7-13. Epub 2006 Oct 19.

8.

Alterations in 5-HT2A receptor signaling in male and female transgenic rats over-expressing either Gq or RGS-insensitive Gq protein.

Shi J, Damjanoska KJ, Zemaitaitis B, Garcia F, Carrasco G, Sullivan NR, She Y, Young KH, Battaglia G, Van De kar LD, Howland DS, Muma NA.

Neuropharmacology. 2006 Sep;51(3):524-35.

PMID:
16769091
9.

Fluoxetine treatment of prepubescent rats produces a selective functional reduction in the 5-HT2A receptor-mediated stimulation of oxytocin.

Landry M, Frasier M, Chen Z, Van De Kar LD, Zhang Y, Garcia F, Battaglia G.

Synapse. 2005 Nov;58(2):102-9.

PMID:
16088947
10.

Heightened responses to stressors in patients with inflammatory bowel disease.

Farhadi A, Keshavarzian A, Van de Kar LD, Jakate S, Domm A, Zhang L, Shaikh M, Banan A, Fields JZ.

Am J Gastroenterol. 2005 Aug;100(8):1796-804.

PMID:
16086717
11.

Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine.

Chen Z, Tetzlaff J, Sripathirathan K, Carrasco GA, Shankaran M, Van De Kar LD, Muma NA, Battaglia G.

Psychopharmacology (Berl). 2005 Jul;180(2):316-26. Epub 2005 Apr 28.

PMID:
15864558
12.

Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo.

Sullivan NR, Crane JW, Damjanoska KJ, Carrasco GA, D'Souza DN, Garcia F, Van de Kar LD.

Naunyn Schmiedebergs Arch Pharmacol. 2005 Jan;371(1):18-26. Epub 2005 Jan 18.

PMID:
15655673
13.

Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and cycling female rats.

Grippo AJ, Sullivan NR, Damjanoska KJ, Crane JW, Carrasco GA, Shi J, Chen Z, Garcia F, Muma NA, Van de Kar LD.

Psychopharmacology (Berl). 2005 Jun;179(4):769-80. Epub 2004 Dec 24.

PMID:
15619113
15.

Estrogen reduces serotonin-1A receptor-mediated oxytocin release and Galpha(i/o/z) proteins in the hypothalamus of ovariectomized rats.

D'Souza DN, Zhang Y, Damjanoska KJ, Carrasco GA, Sullivan NR, Garcia F, Battaglia G, Doncarlos LL, Muma NA, Van de Kar LD.

Neuroendocrinology. 2004;80(1):31-41.

PMID:
15385710
16.

Repeated administration of the 5-HT(1B) receptor antagonist SB-224289 blocks the desensitisation of 5-HT(1B) autoreceptors induced by fluoxetine in rat frontal cortex.

Shalom G, Gur E, Van de Kar LD, Newman ME.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):84-90. Epub 2004 Aug 12.

PMID:
15309378
17.

Estrogen treatment increases the levels of regulator of G protein signaling-Z1 in the hypothalamic paraventricular nucleus: possible role in desensitization of 5-hydroxytryptamine1A receptors.

Carrasco GA, Barker SA, Zhang Y, Damjanoska KJ, Sullivan NR, Garcia F, D'souza DN, Muma NA, van De Kar LD.

Neuroscience. 2004;127(2):261-7.

PMID:
15262317
18.
19.

Short-term cocaine treatment causes neuroadaptive changes in Galphaq and Galpha11 proteins in rats undergoing withdrawal.

Carrasco GA, Damjanoska KJ, D'Souza DN, Zhang Y, Garcia F, Battaglia G, Muma NA, Van de Kar LD.

J Pharmacol Exp Ther. 2004 Oct;311(1):349-55. Epub 2004 Jun 2.

PMID:
15175423
20.

Prenatal cocaine exposure potentiates paroxetine-induced desensitization of 5-HT2A receptor function in adult male rat offspring.

Chen Z, Waimey K, Van de Kar LD, Carrasco GA, Landry M, Battaglia G.

Neuropharmacology. 2004 Jun;46(7):942-53.

PMID:
15081791
21.

Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo.

Zhang Y, Gray TS, D'Souza DN, Carrasco GA, Damjanoska KJ, Dudas B, Garcia F, Zainelli GM, Sullivan Hanley NR, Battaglia G, Muma NA, Van de Kar LD.

J Pharmacol Exp Ther. 2004 Jul;310(1):59-66. Epub 2004 Apr 2.

PMID:
15064330
22.

Agonist-induced serotonin 2A receptor desensitization in the rat frontal cortex and hypothalamus.

Damjanoska KJ, Heidenreich BA, Kindel GH, D'Souza DN, Zhang Y, Garcia F, Battaglia G, Wolf WA, Van de Kar LD, Muma NA.

J Pharmacol Exp Ther. 2004 Jun;309(3):1043-50. Epub 2004 Feb 19.

PMID:
14976228
23.

Chronic fluoxetine-induced desensitization of 5-HT1A and 5-HT1B autoreceptors: regional differences and effects of WAY-100635.

Newman ME, Shalom G, Ran A, Gur E, Van de Kar LD.

Eur J Pharmacol. 2004 Feb 13;486(1):25-30.

PMID:
14751404
24.

Chronic rTMS induces subsensitivity of post-synaptic 5-HT1A receptors in rat hypothalamus.

Gur E, Lerer B, van de Kar LD, Newman ME.

Int J Neuropsychopharmacol. 2004 Sep;7(3):335-40. Epub 2004 Jan 23.

PMID:
14741057
25.

Fluoxetine-induced changes in body weight and 5-HT1A receptor-mediated hormone secretion in rats on a tryptophan-deficient diet.

D'Souza DN, Zhang Y, Garcia F, Battaglia G, Van de Kar LD.

Am J Physiol Regul Integr Comp Physiol. 2004 Feb;286(2):R390-7. Epub 2003 Nov 6.

26.

A region-specific increase in Galphaq and Galpha11 proteins in brains of rats during cocaine withdrawal.

Carrasco GA, Zhang Y, Damjanoska KJ, D'Souza DN, Garcia F, Battaglia G, Muma NA, Van de Kar LD.

J Pharmacol Exp Ther. 2003 Dec;307(3):1012-9. Epub 2003 Oct 8.

PMID:
14534355
27.
28.

Plasma oxytocin in response to pharmaco-challenge to D-fenfluramine and placebo in healthy men.

Lee R, Garcia F, van de Kar LD, Hauger RD, Coccaro EF.

Psychiatry Res. 2003 May 30;118(2):129-36.

PMID:
12798977
29.

Chronic fluoxetine differentially affects 5-hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus.

Damjanoska KJ, Van de Kar LD, Kindel GH, Zhang Y, D'Souza DN, Garcia F, Battaglia G, Muma NA.

J Pharmacol Exp Ther. 2003 Aug;306(2):563-71. Epub 2003 Apr 29.

PMID:
12721328
30.

Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice.

Li Q, Wichems CH, Ma L, Van de Kar LD, Garcia F, Murphy DL.

J Neurochem. 2003 Mar;84(6):1256-65.

31.

Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist.

Damjanoska KJ, Muma NA, Zhang Y, D'Souza DN, Garcia F, Carrasco GA, Kindel GH, Haskins KA, Shankaran M, Petersen BR, Van De Kar LD.

J Pharmacol Exp Ther. 2003 Mar;304(3):1209-16.

PMID:
12604698
32.

Neuroendocrine pharmacology of stress.

Carrasco GA, Van de Kar LD.

Eur J Pharmacol. 2003 Feb 28;463(1-3):235-72. Review.

PMID:
12600714
33.

Ovariectomy-induced increases in hypothalamic serotonin-1A receptor function in rats are prevented by estradiol.

Raap DK, DonCarlos LL, Garcia F, Zhang Y, Muma NA, Battaglia G, Van de Kar LD.

Neuroendocrinology. 2002 Dec;76(6):348-56.

PMID:
12566942
34.

Destruction of serotonergic nerve terminals prevents fluoxetine-induced desensitization of hypothalamic 5-HT(1A) receptors.

D'Souza DN, Zhang Y, Garcia F, Battaglia G, Van De Kar LD.

Psychopharmacology (Berl). 2002 Dec;164(4):392-400. Epub 2002 Sep 14.

PMID:
12457269
35.

Evidence that 5-HT2A receptors in the hypothalamic paraventricular nucleus mediate neuroendocrine responses to (-)DOI.

Zhang Y, Damjanoska KJ, Carrasco GA, Dudas B, D'Souza DN, Tetzlaff J, Garcia F, Hanley NR, Scripathirathan K, Petersen BR, Gray TS, Battaglia G, Muma NA, Van de Kar LD.

J Neurosci. 2002 Nov 1;22(21):9635-42.

36.

Functional effects of chronic electroconvulsive shock on serotonergic 5-HT(1A) and 5-HT(1B) receptor activity in rat hippocampus and hypothalamus.

Gur E, Dremencov E, Garcia F, Van de Kar LD, Lerer B, Newman ME.

Brain Res. 2002 Oct 11;952(1):52-60.

PMID:
12363404
37.

Treatment of cycling female rats with fluoxetine induces desensitization of hypothalamic 5-HT(1A) receptors with no change in 5-HT(2A) receptors.

Van de Kar LD, Raap DK, Battaglia G, Muma NA, Garcia F, DonCarlos LL.

Neuropharmacology. 2002 Jul;43(1):45-54.

PMID:
12213258
38.

Evidence for a mutual interaction between noradrenergic and serotonergic agonists in stimulation of ACTH and corticosterone secretion in the rat.

Weidenfeld J, Feldman S, Itzik A, Van de Kar LD, Newman ME.

Brain Res. 2002 Jun 21;941(1-2):113-7.

PMID:
12031553
39.

Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus.

Gur E, Dremencov E, Van De Kar LD, Lerer B, Newman ME.

Eur J Pharmacol. 2002 Feb 1;436(1-2):57-65.

PMID:
11834247
40.

Characterization of the functional heterologous desensitization of hypothalamic 5-HT(1A) receptors after 5-HT(2A) receptor activation.

Zhang Y, D'Souza D, Raap DK, Garcia F, Battaglia G, Muma NA, Van de Kar LD.

J Neurosci. 2001 Oct 15;21(20):7919-27.

41.
42.

Chronic clomipramine alters presynaptic 5-HT(1B) and postsynaptic 5-HT(1A) receptor sensitivity in rat hypothalamus and hippocampus, respectively.

Newman ME, Gur E, Dremencov E, Garcia F, Lerer B, Van de Kar LD.

Neuropharmacology. 2000 Sep;39(12):2309-17.

PMID:
10974314
43.

Estrogen desensitizes 5-HT(1A) receptors and reduces levels of G(z), G(i1) and G(i3) proteins in the hypothalamus.

Raap DK, DonCarlos L, Garcia F, Muma NA, Wolf WA, Battaglia G, Van de Kar LD.

Neuropharmacology. 2000 Jul 24;39(10):1823-32.

PMID:
10884563
44.
45.

Low dose zolmitriptan as a 5-HT neuroendocrine challenge agent in humans.

Moeller FG, Bjork JM, Dougherty DM, Van de Kar LD, Marsh DM, Swann AC.

Psychoneuroendocrinology. 2000 Aug;25(6):607-18.

PMID:
10840172
46.

Evidence that G(z)-proteins couple to hypothalamic 5-HT(1A) receptors in vivo.

Serres F, Li Q, Garcia F, Raap DK, Battaglia G, Muma NA, Van de Kar LD.

J Neurosci. 2000 May 1;20(9):3095-103.

47.

Prenatal cocaine exposure potentiates 5-HT(2a) receptor function in male and female rat offspring.

Battaglia G, Cabrera-Vera TM, Van De Kar LD.

Synapse. 2000 Mar 1;35(3):163-72.

PMID:
10657023
48.

Long-term fluoxetine produces behavioral anxiolytic effects without inhibiting neuroendocrine responses to conditioned stress in rats.

Zhang Y, Raap DK, Garcia F, Serres F, Ma Q, Battaglia G, Van de Kar LD.

Brain Res. 2000 Feb 7;855(1):58-66.

PMID:
10650130
49.

Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.

Li Q, Wichems C, Heils A, Van De Kar LD, Lesch KP, Murphy DL.

J Pharmacol Exp Ther. 1999 Dec;291(3):999-1007.

PMID:
10565817
50.

Selective serotonin reuptake inhibitors and neuroendocrine function.

Raap DK, Van de Kar LD.

Life Sci. 1999;65(12):1217-35. Review.

PMID:
10503938

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