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Items: 1 to 50 of 150

1.

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.

van den Berg BM, Wang G, Boels MGS, Avramut MC, Jansen E, Sol WMPJ, Lebrin F, van Zonneveld AJ, de Koning EJP, Vink H, Gröne HJ, Carmeliet P, van der Vlag J, Rabelink TJ.

J Am Soc Nephrol. 2019 Jul 15. pii: ASN.2019020192. doi: 10.1681/ASN.2019020192. [Epub ahead of print]

PMID:
31308073
2.

Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury.

Pluijmert NJ, den Haan MC, van Zuylen VL, Steendijk P, de Boer HC, van Zonneveld AJ, Fibbe WE, Schalij MJ, Quax PHA, Atsma DE.

PLoS One. 2019 Jun 14;14(6):e0217582. doi: 10.1371/journal.pone.0217582. eCollection 2019.

3.

Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis.

Bijkerk R, Au YW, Stam W, Duijs JMGJ, Koudijs A, Lievers E, Rabelink TJ, van Zonneveld AJ.

Front Pharmacol. 2019 Mar 11;10:215. doi: 10.3389/fphar.2019.00215. eCollection 2019.

4.

In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion.

Bijkerk R, Esguerra JLS, Ellenbroek JH, Au YW, Hanegraaf MAJ, de Koning EJ, Eliasson L, van Zonneveld AJ.

Nucleic Acid Ther. 2019 Apr;29(2):67-72. doi: 10.1089/nat.2018.0763. Epub 2019 Jan 23.

PMID:
30672723
5.

Neutral endopeptidase inhibitors blunt kidney fibrosis by reducing myofibroblast formation.

Bijkerk R, Aleksinskaya MA, Duijs JMGJ, Veth J, Husen B, Reiche D, Prehn C, Adamski J, Rabelink TJ, De Mey JGR, van Zonneveld AJ.

Clin Sci (Lond). 2019 Jan 22;133(2):239-252. doi: 10.1042/CS20180882. Print 2019 Jan 31.

PMID:
30617188
6.

Vascular Calcification and not Arrhythmia in Idiopathic Atrial Fibrillation Associates with Sex Differences in Diabetic Microvascular Injury miRNA Profiles.

Dudink E, Florijn B, Weijs B, Duijs J, Luermans J, Peeters F, Schurgers L, Wildberger J, Schotten U, Bijkerk R, Crijns HJ, van Zonneveld AJ.

Microrna. 2019;8(2):127-134. doi: 10.2174/2211536608666181122125208.

PMID:
30465521
7.

Understanding netrins and semaphorins in mature endothelial cell biology.

Zhang H, Vreeken D, Bruikman CS, van Zonneveld AJ, van Gils JM.

Pharmacol Res. 2018 Nov;137:1-10. doi: 10.1016/j.phrs.2018.09.015. Epub 2018 Sep 18. Review.

8.

Perfused 3D angiogenic sprouting in a high-throughput in vitro platform.

van Duinen V, Zhu D, Ramakers C, van Zonneveld AJ, Vulto P, Hankemeier T.

Angiogenesis. 2019 Feb;22(1):157-165. doi: 10.1007/s10456-018-9647-0. Epub 2018 Aug 31.

9.

Relaxin receptor deficiency promotes vascular inflammation and impairs outward remodeling in arteriovenous fistulas.

Bezhaeva T, de Vries MR, Geelhoed WJ, van der Veer EP, Versteeg S, van Alem CMA, Voorzaat BM, Eijkelkamp N, van der Bogt KE, Agoulnik AI, van Zonneveld AJ, Quax PHA, Rotmans JI.

FASEB J. 2018 Jun 8:fj201800437R. doi: 10.1096/fj.201800437R. [Epub ahead of print]

10.

MicroRNA-132 controls water homeostasis through regulating MECP2-mediated vasopressin synthesis.

Bijkerk R, Trimpert C, van Solingen C, de Bruin RG, Florijn BW, Kooijman S, van den Berg R, van der Veer EP, Bredewold EOW, Rensen PCN, Rabelink TJ, Humphreys BD, Deen PMT, van Zonneveld AJ.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1129-F1138. doi: 10.1152/ajprenal.00087.2018. Epub 2018 May 30.

PMID:
29846108
11.

96 perfusable blood vessels to study vascular permeability in vitro.

van Duinen V, van den Heuvel A, Trietsch SJ, Lanz HL, van Gils JM, van Zonneveld AJ, Vulto P, Hankemeier T.

Sci Rep. 2017 Dec 22;7(1):18071. doi: 10.1038/s41598-017-14716-y.

12.

Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial β1 Integrin.

Hu S, Liu Y, You T, Heath J, Xu L, Zheng X, Wang A, Wang Y, Li F, Yang F, Cao Y, Zhang H, van Gils JM, van Zonneveld AJ, Jo H, Wu Q, Zhang Y, Tang C, Zhu L.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):335-343. doi: 10.1161/ATVBAHA.117.310491. Epub 2017 Dec 21.

13.

Gender and cardiovascular disease: are sex-biased microRNA networks a driving force behind heart failure with preserved ejection fraction in women?

Florijn BW, Bijkerk R, van der Veer EP, van Zonneveld AJ.

Cardiovasc Res. 2018 Feb 1;114(2):210-225. doi: 10.1093/cvr/cvx223. Review.

PMID:
29186452
14.

Circulating Endothelial Markers in Retinal Vasculopathy With Cerebral Leukoencephalopathy and Systemic Manifestations.

Pelzer N, Bijkerk R, Reinders MEJ, van Zonneveld AJ, Ferrari MD, van den Maagdenberg AMJM, Eikenboom J, Terwindt GM.

Stroke. 2017 Dec;48(12):3301-3307. doi: 10.1161/STROKEAHA.117.018556. Epub 2017 Nov 7.

PMID:
29114091
15.

Deficiency of TLR4 homologue RP105 aggravates outward remodeling in a murine model of arteriovenous fistula failure.

Bezhaeva T, Wong C, de Vries MR, van der Veer EP, van Alem CMA, Que I, Lalai RA, van Zonneveld AJ, Rotmans JI, Quax PHA.

Sci Rep. 2017 Aug 31;7(1):10269. doi: 10.1038/s41598-017-10108-4.

16.

Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.

Boels MGS, Koudijs A, Avramut MC, Sol WMPJ, Wang G, van Oeveren-Rietdijk AM, van Zonneveld AJ, de Boer HC, van der Vlag J, van Kooten C, Eulberg D, van den Berg BM, IJpelaar DHT, Rabelink TJ.

Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22.

17.

Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals.

Reijers JAA, Dane MJC, van Zonneveld AJ, Burggraaf J, Moerland M.

Eur J Drug Metab Pharmacokinet. 2018 Feb;43(1):103-113. doi: 10.1007/s13318-017-0430-1.

18.

Acute Rejection After Kidney Transplantation Associates With Circulating MicroRNAs and Vascular Injury.

Bijkerk R, Florijn BW, Khairoun M, Duijs JMGJ, Ocak G, de Vries APJ, Schaapherder AF, Mallat MJK, de Fijter JW, Rabelink TJ, van Zonneveld AJ, Reinders MEJ.

Transplant Direct. 2017 Jun 19;3(7):e174. doi: 10.1097/TXD.0000000000000699. eCollection 2017 Jul.

19.

Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score.

Montero-Cabezas JM, Karalis I, Wolterbeek R, Kraaijeveld AO, Hoefer IE, Pasterkamp G, Pijls NH, Doevendans PA, Walterberger J, Kuiper J, van Zonneveld AJ, Jukema JW.

Neth Heart J. 2017 Sep;25(9):490-497. doi: 10.1007/s12471-017-1005-0.

20.

Emerging roles for RNA-binding proteins as effectors and regulators of cardiovascular disease.

de Bruin RG, Rabelink TJ, van Zonneveld AJ, van der Veer EP.

Eur Heart J. 2017 May 7;38(18):1380-1388. doi: 10.1093/eurheartj/ehw567. Review.

PMID:
28064149
21.

miRNA-Coordinated Networks as Promising Therapeutic Targets for Acute Kidney Injury.

van Zonneveld AJ, Rabelink TJ, Bijkerk R.

Am J Pathol. 2017 Jan;187(1):20-24. doi: 10.1016/j.ajpath.2016.10.017. Epub 2016 Nov 17. Review.

PMID:
27865759
22.

Promoting Tropoelastin Expression in Arterial and Venous Vascular Smooth Muscle Cells and Fibroblasts for Vascular Tissue Engineering.

Rothuizen TC, Kemp R, Duijs JM, de Boer HC, Bijkerk R, van der Veer EP, Moroni L, van Zonneveld AJ, Weiss AS, Rabelink TJ, Rotmans JI.

Tissue Eng Part C Methods. 2016 Oct;22(10):923-931. doi: 10.1089/ten.TEC.2016.0173. Epub 2016 Sep 28.

PMID:
27604583
23.

Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model.

Wong C, Bezhaeva T, Rothuizen TC, Metselaar JM, de Vries MR, Verbeek FP, Vahrmeijer AL, Wezel A, van Zonneveld AJ, Rabelink TJ, Quax PH, Rotmans JI.

Sci Rep. 2016 Jul 27;6:30439. doi: 10.1038/srep30439.

24.

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.

Boels MG, Avramut MC, Koudijs A, Dane MJ, Lee DH, van der Vlag J, Koster AJ, van Zonneveld AJ, van Faassen E, Gröne HJ, van den Berg BM, Rabelink TJ.

Diabetes. 2016 Aug;65(8):2429-39. doi: 10.2337/db15-1413. Epub 2016 Mar 25.

25.

Silencing of microRNA-132 reduces renal fibrosis by selectively inhibiting myofibroblast proliferation.

Bijkerk R, de Bruin RG, van Solingen C, van Gils JM, Duijs JM, van der Veer EP, Rabelink TJ, Humphreys BD, van Zonneveld AJ.

Kidney Int. 2016 Jun;89(6):1268-80. doi: 10.1016/j.kint.2016.01.029. Epub 2016 Apr 8.

PMID:
27165825
26.

Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation.

Spronk HM, De Jong AM, Verheule S, De Boer HC, Maass AH, Lau DH, Rienstra M, van Hunnik A, Kuiper M, Lumeij S, Zeemering S, Linz D, Kamphuisen PW, Ten Cate H, Crijns HJ, Van Gelder IC, van Zonneveld AJ, Schotten U.

Eur Heart J. 2017 Jan 1;38(1):38-50. doi: 10.1093/eurheartj/ehw119. Epub 2016 Apr 12.

PMID:
27071821
27.

Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression.

de Bruin RG, Shiue L, Prins J, de Boer HC, Singh A, Fagg WS, van Gils JM, Duijs JM, Katzman S, Kraaijeveld AO, Böhringer S, Leung WY, Kielbasa SM, Donahue JP, van der Zande PH, Sijbom R, van Alem CM, Bot I, van Kooten C, Jukema JW, Van Esch H, Rabelink TJ, Kazan H, Biessen EA, Ares M Jr, van Zonneveld AJ, van der Veer EP.

Nat Commun. 2016 Mar 31;7:10846. doi: 10.1038/ncomms10846.

28.

The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression.

de Bruin RG, van der Veer EP, Prins J, Lee DH, Dane MJ, Zhang H, Roeten MK, Bijkerk R, de Boer HC, Rabelink TJ, van Zonneveld AJ, van Gils JM.

Sci Rep. 2016 Feb 24;6:21643. doi: 10.1038/srep21643.

29.

A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail.

Wong CY, de Vries MR, Wang Y, van der Vorst JR, Vahrmeijer AL, van Zonneveld AJ, Hamming JF, Roy-Chaudhury P, Rabelink TJ, Quax PH, Rotmans JI.

J Vis Exp. 2016 Feb 3;(108):e53294. doi: 10.3791/53294.

30.

Modeling the combined effect of RNA-binding proteins and microRNAs in post-transcriptional regulation.

HafezQorani S, Lafzi A, de Bruin RG, van Zonneveld AJ, van der Veer EP, Son YA, Kazan H.

Nucleic Acids Res. 2016 May 19;44(9):e83. doi: 10.1093/nar/gkw048. Epub 2016 Feb 2.

31.

Study on inflammation-related genes and microRNAs, with special emphasis on the vascular repair factor HGF and miR-574-3p, in monocytes and serum of patients with T2D.

Baldeón Rojas L, Weigelt K, de Wit H, Ozcan B, van Oudenaren A, Sempértegui F, Sijbrands E, Grosse L, van Zonneveld AJ, Drexhage HA, Leenen PJ.

Diabetol Metab Syndr. 2016 Jan 15;8:6. doi: 10.1186/s13098-015-0113-5. eCollection 2016.

32.

Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression.

Bijkerk R, van der Pol P, Khairoun M, van Gijlswijk-Jansen DJ, Lievers E, de Vries AP, de Koning EJ, de Fijter HW, Roelen DL, Vossen RH, van Zonneveld AJ, van Kooten C, Reinders ME.

Diabetologia. 2016 Apr;59(4):853-8. doi: 10.1007/s00125-015-3858-3. Epub 2016 Jan 15.

33.

Development and evaluation of in vivo tissue engineered blood vessels in a porcine model.

Rothuizen TC, Damanik FFR, Lavrijsen T, Visser MJT, Hamming JF, Lalai RA, Duijs JMGJ, van Zonneveld AJ, Hoefer IE, van Blitterswijk CA, Rabelink TJ, Moroni L, Rotmans JI.

Biomaterials. 2016 Jan;75:82-90. doi: 10.1016/j.biomaterials.2015.10.023. Epub 2015 Oct 22.

PMID:
26491997
34.

Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention.

Rutten B, Roest M, McClellan EA, Sels JW, Stubbs A, Jukema JW, Doevendans PA, Waltenberger J, van Zonneveld AJ, Pasterkamp G, De Groot PG, Hoefer IE.

Thromb Haemost. 2016 Jan;115(2):353-60. doi: 10.1160/TH15-03-0227. Epub 2015 Oct 1. Erratum in: Thromb Haemost. 2017 Feb 28;117(3):641.

PMID:
26423019
35.

Type 2 Diabetes Monocyte MicroRNA and mRNA Expression: Dyslipidemia Associates with Increased Differentiation-Related Genes but Not Inflammatory Activation.

Baldeón R L, Weigelt K, de Wit H, Ozcan B, van Oudenaren A, Sempértegui F, Sijbrands E, Grosse L, van Zonneveld AJ, Drexhage HA, Leenen PJ.

PLoS One. 2015 Jun 17;10(6):e0129421. doi: 10.1371/journal.pone.0129421. eCollection 2015.

36.

Circulating microRNAs associate with diabetic nephropathy and systemic microvascular damage and normalize after simultaneous pancreas-kidney transplantation.

Bijkerk R, Duijs JM, Khairoun M, Ter Horst CJ, van der Pol P, Mallat MJ, Rotmans JI, de Vries AP, de Koning EJ, de Fijter JW, Rabelink TJ, van Zonneveld AJ, Reinders ME.

Am J Transplant. 2015 Apr;15(4):1081-90. doi: 10.1111/ajt.13072. Epub 2015 Feb 25.

37.

Elastin is a key regulator of outward remodeling in arteriovenous fistulas.

Wong CY, Rothuizen TC, de Vries MR, Rabelink TJ, Hamming JF, van Zonneveld AJ, Quax PH, Rotmans JI.

Eur J Vasc Endovasc Surg. 2015 Apr;49(4):480-6. doi: 10.1016/j.ejvs.2014.12.035. Epub 2015 Feb 18.

38.

A microscopic view on the renal endothelial glycocalyx.

Dane MJ, van den Berg BM, Lee DH, Boels MG, Tiemeier GL, Avramut MC, van Zonneveld AJ, van der Vlag J, Vink H, Rabelink TJ.

Am J Physiol Renal Physiol. 2015 May 1;308(9):F956-66. doi: 10.1152/ajprenal.00532.2014. Epub 2015 Feb 11. Review.

39.

Heart failure with preserved ejection fraction in women: the Dutch Queen of Hearts program.

den Ruijter H, Pasterkamp G, Rutten FH, Lam CS, Chi C, Tan KH, van Zonneveld AJ, Spaanderman M, de Kleijn DP.

Neth Heart J. 2015 Feb;23(2):89-93. doi: 10.1007/s12471-014-0613-1.

40.

Oleic acid increases mitochondrial reactive oxygen species production and decreases endothelial nitric oxide synthase activity in cultured endothelial cells.

Gremmels H, Bevers LM, Fledderus JO, Braam B, van Zonneveld AJ, Verhaar MC, Joles JA.

Eur J Pharmacol. 2015 Mar 15;751:67-72. doi: 10.1016/j.ejphar.2015.01.005. Epub 2015 Jan 13.

PMID:
25595727
41.

Silencing of miRNA-126 in kidney ischemia reperfusion is associated with elevated SDF-1 levels and mobilization of Sca-1+/Lin- progenitor cells.

Bijkerk R, van Solingen C, de Boer HC, de Vries DK, Monge M, van Oeveren-Rietdijk A, van der Veer EP, Schaapherder AF, Rabelink TJ, van Zonneveld AJ.

Microrna. 2014;3(3):144-9.

PMID:
25541911
42.

Increased platelet reactivity is associated with circulating platelet-monocyte complexes and macrophages in human atherosclerotic plaques.

Rutten B, Tersteeg C, Vrijenhoek JE, van Holten TC, Elsenberg EH, Mak-Nienhuis EM, de Borst GJ, Jukema JW, Pijls NH, Waltenberger J, van Zonneveld AJ, Moll FL, McClellan E, Stubbs A, Pasterkamp G, Hoefer I, de Groot PG, Roest M.

PLoS One. 2014 Aug 14;9(8):e105019. doi: 10.1371/journal.pone.0105019. eCollection 2014.

43.

TLR4 accessory molecule RP105 (CD180) regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model.

Bastiaansen AJ, Karper JC, Wezel A, de Boer HC, Welten SM, de Jong RC, Peters EA, de Vries MR, van Oeveren-Rietdijk AM, van Zonneveld AJ, Hamming JF, Nossent AY, Quax PH.

PLoS One. 2014 Jun 19;9(6):e99882. doi: 10.1371/journal.pone.0099882. eCollection 2014.

44.

Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion.

Lee DH, Dane MJ, van den Berg BM, Boels MG, van Teeffelen JW, de Mutsert R, den Heijer M, Rosendaal FR, van der Vlag J, van Zonneveld AJ, Vink H, Rabelink TJ; NEO study group.

PLoS One. 2014 May 9;9(5):e96477. doi: 10.1371/journal.pone.0096477. eCollection 2014.

45.

Hematopoietic microRNA-126 protects against renal ischemia/reperfusion injury by promoting vascular integrity.

Bijkerk R, van Solingen C, de Boer HC, van der Pol P, Khairoun M, de Bruin RG, van Oeveren-Rietdijk AM, Lievers E, Schlagwein N, van Gijlswijk DJ, Roeten MK, Neshati Z, de Vries AA, Rodijk M, Pike-Overzet K, van den Berg YW, van der Veer EP, Versteeg HH, Reinders ME, Staal FJ, van Kooten C, Rabelink TJ, van Zonneveld AJ.

J Am Soc Nephrol. 2014 Aug;25(8):1710-22. doi: 10.1681/ASN.2013060640. Epub 2014 Mar 7.

46.

Association of kidney function with changes in the endothelial surface layer.

Dane MJ, Khairoun M, Lee DH, van den Berg BM, Eskens BJ, Boels MG, van Teeffelen JW, Rops AL, van der Vlag J, van Zonneveld AJ, Reinders ME, Vink H, Rabelink TJ.

Clin J Am Soc Nephrol. 2014 Apr;9(4):698-704. doi: 10.2215/CJN.08160813. Epub 2014 Jan 23.

47.

Increased cytokine response after toll-like receptor stimulation in patients with stable coronary artery disease.

Elsenberg EH, Sels JE, Hillaert MA, Schoneveld AH, van den Dungen NA, van Holten TC, Roest M, Jukema JW, van Zonneveld AJ, de Groot PG, Pijls N, Pasterkamp G, Hoefer IE.

Atherosclerosis. 2013 Dec;231(2):346-51. doi: 10.1016/j.atherosclerosis.2013.09.036. Epub 2013 Oct 10.

PMID:
24267249
48.

Circulating cells as predictors of secondary manifestations of cardiovascular disease: design of the CIRCULATING CELLS study.

Hoefer IE, Sels JW, Jukema JW, Bergheanu S, Biessen E, McClellan E, Daemen M, Doevendans P, de Groot P, Hillaert M, Horsman S, Ilhan M, Kuiper J, Pijls N, Redekop K, van der Spek P, Stubbs A, van de Veer E, Waltenberger J, van Zonneveld AJ, Pasterkamp G.

Clin Res Cardiol. 2013 Nov;102(11):847-56. doi: 10.1007/s00392-013-0607-9. Epub 2013 Aug 23.

PMID:
23975238
49.

Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype.

van der Veer EP, de Bruin RG, Kraaijeveld AO, de Vries MR, Bot I, Pera T, Segers FM, Trompet S, van Gils JM, Roeten MK, Beckers CM, van Santbrink PJ, Janssen A, van Solingen C, Swildens J, de Boer HC, Peters EA, Bijkerk R, Rousch M, Doop M, Kuiper J, Schalij MJ, van der Wal AC, Richard S, van Berkel TJ, Pickering JG, Hiemstra PS, Goumans MJ, Rabelink TJ, de Vries AA, Quax PH, Jukema JW, Biessen EA, van Zonneveld AJ.

Circ Res. 2013 Oct 12;113(9):1065-75. doi: 10.1161/CIRCRESAHA.113.301302. Epub 2013 Aug 20.

PMID:
23963726
50.

Activated platelets correlate with mobilization of naïve CD34(+) cells and generation of CD34(+) /KDR(+) cells in the circulation. A meta-regression analysis.

de Boer HC, van Oeveren-Rietdijk AM, Rotmans JI, Dekkers OM, Rabelink TJ, van Zonneveld AJ.

J Thromb Haemost. 2013 Aug;11(8):1583-92. doi: 10.1111/jth.12315. Review.

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