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Items: 9


Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity.

Liu SY, Joseph NM, Ravindranathan A, Stohr BA, Greenland NY, Vohra P, Hosfield E, Yeh I, Talevich E, Onodera C, Van Ziffle JA, Grenert JP, Bastian BC, Chen YY, Krings G.

Mod Pathol. 2016 Sep;29(9):1012-27. doi: 10.1038/modpathol.2016.97. Epub 2016 Jun 3.


Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation.

Lamagna C, Scapini P, van Ziffle JA, DeFranco AL, Lowell CA.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3311-20. doi: 10.1073/pnas.1300617110. Epub 2013 Aug 12.


Deletion of Syk in neutrophils prevents immune complex arthritis.

Elliott ER, Van Ziffle JA, Scapini P, Sullivan BM, Locksley RM, Lowell CA.

J Immunol. 2011 Oct 15;187(8):4319-30. doi: 10.4049/jimmunol.1100341. Epub 2011 Sep 14.


Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury.

Looney MR, Nguyen JX, Hu Y, Van Ziffle JA, Lowell CA, Matthay MA.

J Clin Invest. 2009 Nov;119(11):3450-61. doi: 10.1172/JCI38432. Epub 2009 Oct 5.


Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection.

Van Ziffle JA, Lowell CA.

Blood. 2009 Nov 26;114(23):4871-82. doi: 10.1182/blood-2009-05-220806. Epub 2009 Oct 1.


Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.

Braun BS, Archard JA, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon K.

Blood. 2006 Sep 15;108(6):2041-4. Epub 2006 May 23.


Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury.

Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA.

J Clin Invest. 2006 Jun;116(6):1615-23. Epub 2006 May 18.


The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase.

M├│csai A, Humphrey MB, Van Ziffle JA, Hu Y, Burghardt A, Spusta SC, Majumdar S, Lanier LL, Lowell CA, Nakamura MC.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6158-63. Epub 2004 Apr 8.


Telomere length in subpopulations of human hematopoietic cells.

Van Ziffle JA, Baerlocher GM, Lansdorp PM.

Stem Cells. 2003;21(6):654-60.

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