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Items: 1 to 50 of 113

1.

Predominantly Antibody-Deficient Patients With Non-infectious Complications Have Reduced Naive B, Treg, Th17, and Tfh17 Cells.

Edwards ESJ, Bosco JJ, Aui PM, Stirling RG, Cameron PU, Chatelier J, Hore-Lacy F, O'Hehir RE, van Zelm MC.

Front Immunol. 2019 Nov 15;10:2593. doi: 10.3389/fimmu.2019.02593. eCollection 2019.

2.

CD Maps-Dynamic Profiling of CD1-CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets.

Kalina T, Fišer K, Pérez-Andrés M, Kuzílková D, Cuenca M, Bartol SJW, Blanco E, Engel P, van Zelm MC.

Front Immunol. 2019 Oct 23;10:2434. doi: 10.3389/fimmu.2019.02434. eCollection 2019.

3.

Successful elevation of circulating acetate and propionate by dietary modulation does not alter T-regulatory cell or cytokine profiles in healthy humans: a pilot study.

Gill PA, van Zelm MC, Ffrench RA, Muir JG, Gibson PR.

Eur J Nutr. 2019 Oct 24. doi: 10.1007/s00394-019-02113-2. [Epub ahead of print]

PMID:
31650328
4.

Recent developments and highlights in immune monitoring of allergen immunotherapy.

van Zelm MC, McKenzie CI, Varese N, Rolland JM, O'Hehir RE.

Allergy. 2019 Dec;74(12):2342-2354. doi: 10.1111/all.14078. Epub 2019 Nov 8. Review.

PMID:
31587309
5.

Induction of IgG2 and IgG4 B-cell memory following sublingual immunotherapy for ryegrass pollen allergy.

Heeringa JJ, McKenzie CI, Varese N, Hew M, Bakx ATCM, Aui PM, Rolland JM, O'Hehir RE, van Zelm MC.

Allergy. 2019 Oct 6. doi: 10.1111/all.14073. [Epub ahead of print]

PMID:
31587307
6.

Quantification of T-Cell and B-Cell Replication History in Aging, Immunodeficiency, and Newborn Screening.

Verstegen RHJ, Aui PM, Watson E, De Jong S, Bartol SJW, Bosco JJ, Cameron PU, Stirling RG, de Vries E, van Dongen JJM, van Zelm MC.

Front Immunol. 2019 Aug 29;10:2084. doi: 10.3389/fimmu.2019.02084. eCollection 2019.

7.

Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data.

Gervin K, Salas LA, Bakulski KM, van Zelm MC, Koestler DC, Wiencke JK, Duijts L, Moll HA, Kelsey KT, Kobor MS, Lyle R, Christensen BC, Felix JF, Jones MJ.

Clin Epigenetics. 2019 Aug 27;11(1):125. doi: 10.1186/s13148-019-0717-y.

8.

Associations of Th2, Th17, Treg cells, and IgA+ memory B cells with atopic disease in children: The Generation R Study.

Looman KIM, van Meel ER, Grosserichter-Wagener C, Vissers FJM, Klingenberg JH, de Jong NW, de Jongste JC, Pasmans SGMA, Duijts L, van Zelm MC, Moll HA.

Allergy. 2019 Aug 6. doi: 10.1111/all.14010. [Epub ahead of print]

PMID:
31385614
9.

Impaired memory B-cell development and antibody maturation with a skewing toward IgE in patients with STAT3 hyper-IgE syndrome.

van de Veen W, Krätz CE, McKenzie CI, Aui PM, Neumann J, van Noesel CJM, Wirz OF, Hagl B, Kröner C, Spielberger BD, Akdis CA, van Zelm MC, Akdis M, Renner ED.

Allergy. 2019 Dec;74(12):2394-2405. doi: 10.1111/all.13969. Epub 2019 Aug 16.

PMID:
31269238
10.

EuroFlow-Based Flowcytometric Diagnostic Screening and Classification of Primary Immunodeficiencies of the Lymphoid System.

van Dongen JJM, van der Burg M, Kalina T, Perez-Andres M, Mejstrikova E, Vlkova M, Lopez-Granados E, Wentink M, Kienzler AK, Philippé J, Sousa AE, van Zelm MC, Blanco E, Orfao A.

Front Immunol. 2019 Jun 13;10:1271. doi: 10.3389/fimmu.2019.01271. eCollection 2019.

11.

Functional Antibody Responses Following Allogeneic Stem Cell Transplantation for TP53 Mutant pre-B-ALL in a Patient With X-Linked Agammaglobulinemia.

van Zelm MC, Pumar M, Shuttleworth P, Aui PM, Smart JM, Grigg A, Bosco JJ.

Front Immunol. 2019 Apr 26;10:895. doi: 10.3389/fimmu.2019.00895. eCollection 2019.

12.

Impaired STAT3-Dependent Upregulation of IL2Rα in B Cells of a Patient With a STAT1 Gain-of-Function Mutation.

van Zelm MC, Bosco JJ, Aui PM, De Jong S, Hore-Lacy F, O'Hehir RE, Stirling RG, Cameron PU.

Front Immunol. 2019 Apr 24;10:768. doi: 10.3389/fimmu.2019.00768. eCollection 2019.

13.

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming.

Ohlin M, Scheepers C, Corcoran M, Lees WD, Busse CE, Bagnara D, Thörnqvist L, Bürckert JP, Jackson KJL, Ralph D, Schramm CA, Marthandan N, Breden F, Scott J, Matsen Iv FA, Greiff V, Yaari G, Kleinstein SH, Christley S, Sherkow JS, Kossida S, Lefranc MP, van Zelm MC, Watson CT, Collins AM.

Front Immunol. 2019 Mar 18;10:435. doi: 10.3389/fimmu.2019.00435. eCollection 2019. Review.

14.

Differences in Systemic IgA Reactivity and Circulating Th Subsets in Healthy Volunteers With Specific Microbiota Enterotypes.

Grosserichter-Wagener C, Radjabzadeh D, van der Weide H, Smit KN, Kraaij R, Hays JP, van Zelm MC.

Front Immunol. 2019 Mar 7;10:341. doi: 10.3389/fimmu.2019.00341. eCollection 2019.

15.

The EuroFlow PID Orientation Tube for Flow Cytometric Diagnostic Screening of Primary Immunodeficiencies of the Lymphoid System.

van der Burg M, Kalina T, Perez-Andres M, Vlkova M, Lopez-Granados E, Blanco E, Bonroy C, Sousa AE, Kienzler AK, Wentink M, Mejstríková E, Šinkorova V, Stuchly J, van Zelm MC, Orfao A, van Dongen JJM.

Front Immunol. 2019 Mar 4;10:246. doi: 10.3389/fimmu.2019.00246. eCollection 2019.

16.

Studying the Replication History of Human B Lymphocytes by Real-Time Quantitative (RQ-)PCR.

van Zelm MC.

Methods Mol Biol. 2019;1956:127-138. doi: 10.1007/978-1-4939-9151-8_6.

PMID:
30779033
17.

Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands.

Laksono BM, de Vries RD, Verburgh RJ, Visser EG, de Jong A, Fraaij PLA, Ruijs WLM, Nieuwenhuijse DF, van den Ham HJ, Koopmans MPG, van Zelm MC, Osterhaus ADME, de Swart RL.

Nat Commun. 2018 Nov 23;9(1):4944. doi: 10.1038/s41467-018-07515-0.

18.

The Rare Anaphylaxis-Associated FcγRIIa3 Exhibits Distinct Characteristics From the Canonical FcγRIIa1.

Anania JC, Trist HM, Palmer CS, Tan PS, Kouskousis BP, Chenoweth AM, Kent SJ, Mackay GA, Hoi A, Koelmeyer R, Slade C, Bryant VL, Hodgkin PD, Aui PM, van Zelm MC, Wines BD, Hogarth PM.

Front Immunol. 2018 Aug 20;9:1809. doi: 10.3389/fimmu.2018.01809. eCollection 2018.

19.

Absence of Surface IgD Does Not Impair Naive B Cell Homeostasis or Memory B Cell Formation in IGHD Haploinsufficient Humans.

Nechvatalova J, Bartol SJW, Chovancova Z, Boon L, Vlkova M, van Zelm MC.

J Immunol. 2018 Oct 1;201(7):1928-1935. doi: 10.4049/jimmunol.1800767. Epub 2018 Aug 24.

20.

Deficiencies in the CD19 complex.

Wentink MWJ, van Zelm MC, van Dongen JJM, Warnatz K, van der Burg M.

Clin Immunol. 2018 Oct;195:82-87. doi: 10.1016/j.clim.2018.07.017. Epub 2018 Jul 31. Review.

PMID:
30075290
21.

Delayed Diagnosis and Complications of Predominantly Antibody Deficiencies in a Cohort of Australian Adults.

Slade CA, Bosco JJ, Binh Giang T, Kruse E, Stirling RG, Cameron PU, Hore-Lacy F, Sutherland MF, Barnes SL, Holdsworth S, Ojaimi S, Unglik GA, De Luca J, Patel M, McComish J, Spriggs K, Tran Y, Auyeung P, Nicholls K, O'Hehir RE, Hodgkin PD, Douglass JA, Bryant VL, van Zelm MC.

Front Immunol. 2018 May 14;9:694. doi: 10.3389/fimmu.2018.00694. eCollection 2018.

22.

Review article: short chain fatty acids as potential therapeutic agents in human gastrointestinal and inflammatory disorders.

Gill PA, van Zelm MC, Muir JG, Gibson PR.

Aliment Pharmacol Ther. 2018 Jul;48(1):15-34. doi: 10.1111/apt.14689. Epub 2018 May 3. Review.

PMID:
29722430
23.

Treatment for moderate to severe atopic dermatitis in alpine and moderate maritime climates differentially affects helper T cells and memory B cells in children.

Heeringa JJ, Fieten KB, Bruins FM, van Hoffen E, Knol EF, Pasmans SGMA, van Zelm MC.

Clin Exp Allergy. 2018 Jun;48(6):679-690. doi: 10.1111/cea.13136. Epub 2018 Apr 17.

PMID:
29575251
24.

Dietary Patterns After the Weaning and Lactation Period Are Associated With Celiac Disease Autoimmunity in Children.

Barroso M, Beth SA, Voortman T, Jaddoe VWV, van Zelm MC, Moll HA, Kiefte-de Jong JC.

Gastroenterology. 2018 Jun;154(8):2087-2096.e7. doi: 10.1053/j.gastro.2018.02.024. Epub 2018 Mar 2.

PMID:
29481779
25.

Epidemic Thunderstorm Asthma Protection with Five-Grass Pollen Tablet Sublingual Immunotherapy: A Clinical Trial.

O'Hehir RE, Varese NP, Deckert K, Zubrinich CM, van Zelm MC, Rolland JM, Hew M.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):126-128. doi: 10.1164/rccm.201711-2337LE. No abstract available.

PMID:
29461859
26.

In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells.

Laksono BM, Grosserichter-Wagener C, de Vries RD, Langeveld SAG, Brem MD, van Dongen JJM, Katsikis PD, Koopmans MPG, van Zelm MC, de Swart RL.

J Virol. 2018 Mar 28;92(8). pii: e00131-18. doi: 10.1128/JVI.00131-18. Print 2018 Apr 15.

27.

Age-Dependent Pre-Vaccination Immunity Affects the Immunogenicity of Varicella Zoster Vaccination in Middle-aged Adults.

van der Heiden M, de Rond LGH, van Zelm MC, Berbers GAM, Boots AMH, Buisman AM.

Front Immunol. 2018 Jan 23;9:46. doi: 10.3389/fimmu.2018.00046. eCollection 2018.

28.

IgE-expressing memory B cells and plasmablasts are increased in blood of children with asthma, food allergy, and atopic dermatitis.

Heeringa JJ, Rijvers L, Arends NJ, Driessen GJ, Pasmans SG, van Dongen JJM, de Jongste JC, van Zelm MC.

Allergy. 2018 Jun;73(6):1331-1336. doi: 10.1111/all.13421. Epub 2018 Mar 30.

PMID:
29380876
29.

An Explorative Biomarker Study for Vaccine Responsiveness after a Primary Meningococcal Vaccination in Middle-Aged Adults.

van der Heiden M, Berbers GAM, Fuentes S, van Zelm MC, Boots AMH, Buisman AM.

Front Immunol. 2018 Jan 11;8:1962. doi: 10.3389/fimmu.2017.01962. eCollection 2017.

30.

Reply.

Karim AF, Heeringa JJ, van Laar JAM, Verdijk RM, Dik WA, Paridaens AD, van Hagen PM, van Zelm MC.

J Allergy Clin Immunol. 2018 May;141(5):1958-1960.e4. doi: 10.1016/j.jaci.2017.11.016. Epub 2018 Jan 10. No abstract available.

PMID:
29329899
31.

Expansion of blood IgG4+ B, TH2, and regulatory T cells in patients with IgG4-related disease.

Heeringa JJ, Karim AF, van Laar JAM, Verdijk RM, Paridaens D, van Hagen PM, van Zelm MC.

J Allergy Clin Immunol. 2018 May;141(5):1831-1843.e10. doi: 10.1016/j.jaci.2017.07.024. Epub 2017 Aug 19.

PMID:
28830675
32.

Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals.

Magri G, Comerma L, Pybus M, Sintes J, Lligé D, Segura-Garzón D, Bascones S, Yeste A, Grasset EK, Gutzeit C, Uzzan M, Ramanujam M, van Zelm MC, Albero-González R, Vazquez I, Iglesias M, Serrano S, Márquez L, Mercade E, Mehandru S, Cerutti A.

Immunity. 2017 Jul 18;47(1):118-134.e8. doi: 10.1016/j.immuni.2017.06.013. Epub 2017 Jul 11.

33.

The role of vitamin D on circulating memory T cells in children: The Generation R study.

Looman KIM, Jansen MAE, Voortman T, van den Heuvel D, Jaddoe VWV, Franco OH, van Zelm MC, Moll HA.

Pediatr Allergy Immunol. 2017 Sep;28(6):579-587. doi: 10.1111/pai.12754. Epub 2017 Aug 7.

PMID:
28686349
34.

Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age.

de Jong BG, IJspeert H, Marques L, van der Burg M, van Dongen JJ, Loos BG, van Zelm MC.

Immunol Cell Biol. 2017 Oct;95(9):744-752. doi: 10.1038/icb.2017.43. Epub 2017 May 26. Erratum in: Immunol Cell Biol. 2019 Jan;97(1):112-113.

35.

Abnormalities in CD57+ cytotoxic T cells and Vδ1+ γδT cells in subclinical celiac disease in childhood are affected by cytomegalovirus. The Generation R Study.

Jansen MAE, van den Heuvel D, Jaddoe VWV, van Zelm MC, Moll HA.

Clin Immunol. 2017 Oct;183:233-239. doi: 10.1016/j.clim.2017.04.008. Epub 2017 Apr 26.

PMID:
28456719
36.

No Interactive Effects of Sex and Persistent Cytomegalovirus on Immune Phenotypes in Young Children: The Generation R Study.

Jansen MAE, van den Heuvel D, Jaddoe VWV, Moll HA, van Zelm MC.

J Infect Dis. 2017 Mar 15;215(6):883-888. doi: 10.1093/infdis/jix064.

PMID:
28453846
37.

Immunopathogenesis of granulomas in chronic autoinflammatory diseases.

Timmermans WM, van Laar JA, van Hagen PM, van Zelm MC.

Clin Transl Immunology. 2016 Dec 16;5(12):e118. doi: 10.1038/cti.2016.75. eCollection 2016 Dec. Review.

38.

Ethnic differences in coeliac disease autoimmunity in childhood: the Generation R Study.

Jansen MAE, Beth SA, van den Heuvel D, Kiefte-de Jong JC, Raat H, Jaddoe VWV, van Zelm MC, Moll HA.

Arch Dis Child. 2017 Jun;102(6):529-534. doi: 10.1136/archdischild-2016-311343. Epub 2017 Jan 4.

PMID:
28052882
39.

Effects of nongenetic factors on immune cell dynamics in early childhood: The Generation R Study.

van den Heuvel D, Jansen MAE, Nasserinejad K, Dik WA, van Lochem EG, Bakker-Jonges LE, Bouallouch-Charif H, Jaddoe VWV, Hooijkaas H, van Dongen JJM, Moll HA, van Zelm MC.

J Allergy Clin Immunol. 2017 Jun;139(6):1923-1934.e17. doi: 10.1016/j.jaci.2016.10.023. Epub 2016 Nov 29.

PMID:
27913304
40.

T and B Cell Markers in Dried Blood Spots of Neonates with Congenital Cytomegalovirus Infection: B Cell Numbers at Birth Are Associated with Long-Term Outcomes.

Rovito R, Korndewal MJ, van Zelm MC, Ziagkos D, Wessels E, van der Burg M, Kroes AC, Langerak AW, Vossen AC.

J Immunol. 2017 Jan 1;198(1):102-109. Epub 2016 Nov 30.

41.

Transient reduction in IgA+ and IgG+ memory B cell numbers in young EBV-seropositive children: the Generation R Study.

van den Heuvel D, Jansen MA, Bell AI, Rickinson AB, Jaddoe VW, van Dongen JJ, Moll HA, van Zelm MC.

J Leukoc Biol. 2017 Apr;101(4):949-956. doi: 10.1189/jlb.5VMAB0616-283R. Epub 2016 Nov 7.

PMID:
27821468
42.

Chronic signs of memory B cell activation in patients with Behçet's disease are partially restored by anti-tumour necrosis factor treatment.

van der Houwen TB, van Hagen PM, Timmermans WM, Bartol SJ, Lam KH, Kappen JH, van Zelm MC, van Laar JA.

Rheumatology (Oxford). 2017 Jan;56(1):134-144. doi: 10.1093/rheumatology/kew366. Epub 2016 Oct 15.

PMID:
27744360
43.

Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin.

Rother MB, Jensen K, van der Burg M, van de Bovenkamp FS, Kroek R, van IJcken WF, van der Velden VH, Cupedo T, Olstad OK, van Dongen JJ, van Zelm MC.

Sci Rep. 2016 Sep 23;6:33924. doi: 10.1038/srep33924.

44.

Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition.

Gervin K, Page CM, Aass HC, Jansen MA, Fjeldstad HE, Andreassen BK, Duijts L, van Meurs JB, van Zelm MC, Jaddoe VW, Nordeng H, Knudsen GP, Magnus P, Nystad W, Staff AC, Felix JF, Lyle R.

Epigenetics. 2016 Sep;11(9):690-698.

45.

Is there a pathogenic role for IgE in psoriasis?

Heeringa JJ, van Zelm MC.

Br J Dermatol. 2016 Jul;175(1):16-7. doi: 10.1111/bjd.14607. No abstract available.

PMID:
27484269
46.

Differentiation stage of myeloma plasma cells: biological and clinical significance.

Paiva B, Puig N, Cedena MT, de Jong BG, Ruiz Y, Rapado I, Martinez-Lopez J, Cordon L, Alignani D, Delgado JA, van Zelm MC, Van Dongen JJ, Pascual M, Agirre X, Prosper F, Martín-Subero JI, Vidriales MB, Gutierrez NC, Hernandez MT, Oriol A, Echeveste MA, Gonzalez Y, Johnson SK, Epstein J, Barlogie B, Morgan GJ, Orfao A, Blade J, Mateos MV, Lahuerta JJ, San-Miguel JF.

Leukemia. 2017 Feb;31(2):382-392. doi: 10.1038/leu.2016.211. Epub 2016 Aug 1.

47.

B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy.

Timmermans WM, van Laar JA, van der Houwen TB, Kamphuis LS, Bartol SJ, Lam KH, Ouwendijk RJ, Sparrow MP, Gibson PR, van Hagen PM, van Zelm MC.

PLoS One. 2016 Jul 28;11(7):e0160103. doi: 10.1371/journal.pone.0160103. eCollection 2016.

48.

Generation R birth cohort study shows that specific enamel defects were not associated with elevated serum transglutaminase type 2 antibodies.

Beth SA, Jansen MA, Elfrink ME, Kiefte-de Jong JC, Wolvius EB, Jaddoe VW, van Zelm MC, Moll HA.

Acta Paediatr. 2016 Oct;105(10):e485-91. doi: 10.1111/apa.13533. Epub 2016 Aug 16.

PMID:
27439586
49.

The Human Thymus Is Enriched for Autoreactive B Cells.

Rother MB, Schreurs MW, Kroek R, Bartol SJ, van Dongen JJ, van Zelm MC.

J Immunol. 2016 Jul 15;197(2):441-8. doi: 10.4049/jimmunol.1501992. Epub 2016 Jun 3.

50.

Differential effects of Cytomegalovirus carriage on the immune phenotype of middle-aged males and females.

van der Heiden M, van Zelm MC, Bartol SJW, de Rond LGH, Berbers GAM, Boots AMH, Buisman AM.

Sci Rep. 2016 May 31;6:26892. doi: 10.1038/srep26892.

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