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Items: 1 to 50 of 58

1.

HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.

Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J.

Autophagy. 2019 Apr 14:1-18. doi: 10.1080/15548627.2019.1596483. [Epub ahead of print]

PMID:
30982460
2.

Type-1 interferons prolong the lifespan of neutrophils by interfering with members of the apoptotic cascade.

Aga E, Mukherjee A, Rane D, More V, Patil T, van Zandbergen G, Solbach W, Dandapat J, Tackenberg H, Ohms M, Sarkar A, Laskay T.

Cytokine. 2018 Dec;112:21-26. doi: 10.1016/j.cyto.2018.06.027. Epub 2018 Jul 7.

PMID:
30554594
3.

Anti-Tumor Necrosis Factor α Therapeutics Differentially Affect Leishmania Infection of Human Macrophages.

Arens K, Filippis C, Kleinfelder H, Goetzee A, Reichmann G, Crauwels P, Waibler Z, Bagola K, van Zandbergen G.

Front Immunol. 2018 Jul 31;9:1772. doi: 10.3389/fimmu.2018.01772. eCollection 2018.

4.

Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development.

Zimara N, Chanyalew M, Aseffa A, van Zandbergen G, Lepenies B, Schmid M, Weiss R, Rascle A, Wege AK, Jantsch J, Schatz V, Brown GD, Ritter U.

Front Immunol. 2018 Feb 26;9:263. doi: 10.3389/fimmu.2018.00263. eCollection 2018.

5.

Nivolumab Enhances In Vitro Effector Functions of PD-1+ T-Lymphocytes and Leishmania-Infected Human Myeloid Cells in a Host Cell-Dependent Manner.

Filippis C, Arens K, Noubissi Nzeteu GA, Reichmann G, Waibler Z, Crauwels P, van Zandbergen G.

Front Immunol. 2017 Dec 22;8:1880. doi: 10.3389/fimmu.2017.01880. eCollection 2017.

6.

LC3-associated phagocytosis in microbial pathogenesis.

Schille S, Crauwels P, Bohn R, Bagola K, Walther P, van Zandbergen G.

Int J Med Microbiol. 2018 Jan;308(1):228-236. doi: 10.1016/j.ijmm.2017.10.014. Epub 2017 Nov 21. Review.

7.

In silico prediction of Leishmania major-specific CD8+ epitopes.

Dietze-Schwonberg K, Grewe B, Brosch S, Kuharev J, van Zandbergen G, Rammensee HG, Tenzer S, von Stebut E.

Exp Dermatol. 2017 Sep;26(9):838-840. doi: 10.1111/exd.13295. Epub 2017 Apr 20.

PMID:
28094883
8.

Past, present and future of immunology in Mainz.

Waisman A, Hövelmeyer N, Diefenbach A, Schuppan D, Reddehase MJ, Kleinert H, Kaina B, Grabbe S, Galle PR, Theobald M, Zipp F, Sahin U, Türeci Ö, Kreiter S, Langguth P, Decker H, van Zandbergen G, Schild H.

Cell Immunol. 2016 Oct;308:1-6. doi: 10.1016/j.cellimm.2016.09.001. No abstract available.

PMID:
27719802
9.

In vitro permissiveness of bovine neutrophils and monocyte derived macrophages to Leishmania donovani of Ethiopian isolate.

Tasew G, Gadisa E, Abera A, Zewude A, Chanyalew M, Aseffa A, Abebe M, Ritter U, van Zandbergen G, Laskay T, Tafess K.

Parasit Vectors. 2016 Apr 18;9:218. doi: 10.1186/s13071-016-1441-5.

10.

An Emerging Approach for Parallel Quantification of Intracellular Protozoan Parasites and Host Cell Characterization Using TissueFAXS Cytometry.

Schmid M, Dufner B, Dürk J, Bedal K, Stricker K, Prokoph LA, Koch C, Wege AK, Zirpel H, van Zandbergen G, Ecker R, Boghiu B, Ritter U.

PLoS One. 2015 Oct 21;10(10):e0139866. doi: 10.1371/journal.pone.0139866. eCollection 2015.

11.

Mechanisms of apoptosis inhibition in Chlamydia pneumoniae-infected neutrophils.

Sarkar A, Möller S, Bhattacharyya A, Behnen M, Rupp J, van Zandbergen G, Solbach W, Laskay T.

Int J Med Microbiol. 2015 Sep;305(6):493-500. doi: 10.1016/j.ijmm.2015.04.006. Epub 2015 May 8.

PMID:
26005182
12.

Danger signal-dependent activation of human dendritic cells by plasma-derived factor VIII products.

Miller L, Weissmüller S, Ringler E, Crauwels P, van Zandbergen G, Seitz R, Waibler Z; ABIRISK consortium.

Thromb Haemost. 2015 Aug;114(2):268-76. doi: 10.1160/TH14-09-0789. Epub 2015 May 7.

PMID:
25947149
13.

AP-1 Transcription Factor Serves as a Molecular Switch between Chlamydia pneumoniae Replication and Persistence.

Krämer S, Crauwels P, Bohn R, Radzimski C, Szaszák M, Klinger M, Rupp J, van Zandbergen G.

Infect Immun. 2015 Jul;83(7):2651-60. doi: 10.1128/IAI.03083-14. Epub 2015 Apr 20.

14.

Apoptotic-like Leishmania exploit the host's autophagy machinery to reduce T-cell-mediated parasite elimination.

Crauwels P, Bohn R, Thomas M, Gottwalt S, Jäckel F, Krämer S, Bank E, Tenzer S, Walther P, Bastian M, van Zandbergen G.

Autophagy. 2015;11(2):285-97. doi: 10.1080/15548627.2014.998904. Erratum in: Autophagy. 2015;11(8):1439.

15.

Recombinant human IgA1 and IgA2 autoantibodies to type VII collagen induce subepidermal blistering ex vivo.

Recke A, Trog LM, Pas HH, Vorobyev A, Abadpour A, Jonkman MF, van Zandbergen G, Kauderer C, Zillikens D, Vidarsson G, Ludwig RJ.

J Immunol. 2014 Aug 15;193(4):1600-8. doi: 10.4049/jimmunol.1400160. Epub 2014 Jul 14.

16.

CD14-dependent monocyte isolation enhances phagocytosis of listeria monocytogenes by proinflammatory, GM-CSF-derived macrophages.

Neu C, Sedlag A, Bayer C, Förster S, Crauwels P, Niess JH, van Zandbergen G, Frascaroli G, Riedel CU.

PLoS One. 2013 Jun 11;8(6):e66898. doi: 10.1371/journal.pone.0066898. Print 2013.

17.

The β-hemolysin and intracellular survival of Streptococcus agalactiae in human macrophages.

Sagar A, Klemm C, Hartjes L, Mauerer S, van Zandbergen G, Spellerberg B.

PLoS One. 2013 Apr 4;8(4):e60160. doi: 10.1371/journal.pone.0060160. Print 2013.

18.

Abelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophages.

Bruns H, Stegelmann F, Fabri M, Döhner K, van Zandbergen G, Wagner M, Skinner M, Modlin RL, Stenger S.

J Immunol. 2012 Oct 15;189(8):4069-78. doi: 10.4049/jimmunol.1201538. Epub 2012 Sep 17.

19.

Leishmania major parasite stage-dependent host cell invasion and immune evasion.

Wenzel UA, Bank E, Florian C, Förster S, Zimara N, Steinacker J, Klinger M, Reiling N, Ritter U, van Zandbergen G.

FASEB J. 2012 Jan;26(1):29-39. doi: 10.1096/fj.11-184895. Epub 2011 Sep 9.

PMID:
21908716
20.

High-level fluorescence labeling of gram-positive pathogens.

Aymanns S, Mauerer S, van Zandbergen G, Wolz C, Spellerberg B.

PLoS One. 2011;6(6):e19822. doi: 10.1371/journal.pone.0019822. Epub 2011 Jun 22.

21.

The protective Th1 response in mice is induced in the T-cell zone only three weeks after infection with Leishmania major and not during early T-cell activation.

Barthelmann J, Nietsch J, Blessenohl M, Laskay T, van Zandbergen G, Westermann J, Kalies K.

Med Microbiol Immunol. 2012 Feb;201(1):25-35. doi: 10.1007/s00430-011-0201-6. Epub 2011 May 6.

PMID:
21547563
22.

Measuring the killing of intracellular pathogens: Leishmania.

Stenger S, van Zandbergen G.

Curr Protoc Immunol. 2011 Apr;Chapter 14:Unit14.23. doi: 10.1002/0471142735.im1423s93.

PMID:
21462165
23.

Impact of protozoan cell death on parasite-host interactions and pathogenesis.

Lüder CG, Campos-Salinas J, Gonzalez-Rey E, van Zandbergen G.

Parasit Vectors. 2010 Dec 2;3:116. doi: 10.1186/1756-3305-3-116.

24.

Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo.

Roth A, König P, van Zandbergen G, Klinger M, Hellwig-Bürgel T, Däubener W, Bohlmann MK, Rupp J.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19502-7. doi: 10.1073/pnas.1008178107. Epub 2010 Oct 25.

25.

The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells.

Fahrer J, Rieger J, van Zandbergen G, Barth H.

Biol Chem. 2010 Nov;391(11):1315-25. doi: 10.1515/BC.2010.132.

PMID:
20868225
26.

Programmed cell death in unicellular parasites: a prerequisite for sustained infection?

van Zandbergen G, Lüder CG, Heussler V, Duszenko M.

Trends Parasitol. 2010 Oct;26(10):477-83. doi: 10.1016/j.pt.2010.06.008. Epub 2010 Jun 28.

PMID:
20591738
27.

Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major.

Lamerz AC, Damerow S, Kleczka B, Wiese M, van Zandbergen G, Lamerz J, Wenzel A, Hsu FF, Turk J, Beverley SM, Routier FH.

Glycobiology. 2010 Jul;20(7):872-82. doi: 10.1093/glycob/cwq045. Epub 2010 Mar 24.

28.

Phagocytosis of apoptotic cells by neutrophil granulocytes: diminished proinflammatory neutrophil functions in the presence of apoptotic cells.

Esmann L, Idel C, Sarkar A, Hellberg L, Behnen M, Möller S, van Zandbergen G, Klinger M, Köhl J, Bussmeyer U, Solbach W, Laskay T.

J Immunol. 2010 Jan 1;184(1):391-400. doi: 10.4049/jimmunol.0900564. Epub 2009 Nov 30.

29.

Impairment of gamma interferon signaling in human neutrophils infected with Anaplasma phagocytophilum.

Bussmeyer U, Sarkar A, Broszat K, Lüdemann T, Möller S, van Zandbergen G, Bogdan C, Behnen M, Dumler JS, von Loewenich FD, Solbach W, Laskay T.

Infect Immun. 2010 Jan;78(1):358-63. doi: 10.1128/IAI.01005-09. Epub 2009 Oct 26.

30.

Lipoxin A4 receptor dependent leishmania infection.

Wenzel A, Van Zandbergen G.

Autoimmunity. 2009 May;42(4):331-3.

PMID:
19811292
31.

Are neutrophils important host cells for Leishmania parasites?

Ritter U, Frischknecht F, van Zandbergen G.

Trends Parasitol. 2009 Nov;25(11):505-10. doi: 10.1016/j.pt.2009.08.003. Epub 2009 Sep 15.

PMID:
19762280
32.

Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages.

Rupp J, Pfleiderer L, Jugert C, Moeller S, Klinger M, Dalhoff K, Solbach W, Stenger S, Laskay T, van Zandbergen G.

PLoS One. 2009 Jun 23;4(6):e6020. doi: 10.1371/journal.pone.0006020.

33.

Neutrophil granulocytes as host cells and transport vehicles for intracellular pathogens: apoptosis as infection-promoting factor.

Laskay T, van Zandbergen G, Solbach W.

Immunobiology. 2008;213(3-4):183-91. doi: 10.1016/j.imbio.2007.11.010. Epub 2008 Feb 8. Review.

PMID:
18406366
34.

Apoptosis driven infection.

van Zandbergen G, Solbach W, Laskay T.

Autoimmunity. 2007 Jun;40(4):349-52. Review.

PMID:
17516227
35.

Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.

Rupp J, Gieffers J, Klinger M, van Zandbergen G, Wrase R, Maass M, Solbach W, Deiwick J, Hellwig-Burgel T.

Cell Microbiol. 2007 Sep;9(9):2181-91. Epub 2007 May 8.

PMID:
17490410
36.

Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence.

Kleczka B, Lamerz AC, van Zandbergen G, Wenzel A, Gerardy-Schahn R, Wiese M, Routier FH.

J Biol Chem. 2007 Apr 6;282(14):10498-505. Epub 2007 Feb 6.

37.

Direct stimulatory effects of the TLR2/6 ligand bacterial lipopeptide MALP-2 on neutrophil granulocytes.

Wilde I, Lotz S, Engelmann D, Starke A, van Zandbergen G, Solbach W, Laskay T.

Med Microbiol Immunol. 2007 Jun;196(2):61-71. Epub 2006 Sep 28.

PMID:
17006695
38.

Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum.

van Zandbergen G, Bollinger A, Wenzel A, Kamhawi S, Voll R, Klinger M, Müller A, Hölscher C, Herrmann M, Sacks D, Solbach W, Laskay T.

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13837-42. Epub 2006 Aug 31. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16615.

39.

Transmission of Chlamydia pneumoniae infection from blood monocytes to vascular cells in a novel transendothelial migration model.

Rupp J, Koch M, van Zandbergen G, Solbach W, Brandt E, Maass M.

FEMS Microbiol Lett. 2005 Jan 15;242(2):203-8. Erratum in: FEMS Microbiol Lett. 2005 Sep 1;250(1):171. vanZandbergen, Ger [corrected to van Zandbergen, Ger].

40.

Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages.

van Zandbergen G, Klinger M, Mueller A, Dannenberg S, Gebert A, Solbach W, Laskay T.

J Immunol. 2004 Dec 1;173(11):6521-5.

41.

Enhanced PMN response in chronic bronchitis and community-acquired pneumonia.

Strassburg A, Droemann D, van Zandbergen G, Kothe H, Dalhoff K.

Eur Respir J. 2004 Nov;24(5):772-8.

42.

Injection of recombinant FcalphaRI/CD89 in mice does not induce mesangial IgA deposition.

van der Boog PJ, van Kooten C, van Zandbergen G, Klar-Mohamad N, Oortwijn B, Bos NA, van Remoortere A, Hokke CH, de Fijter JW, Daha MR.

Nephrol Dial Transplant. 2004 Nov;19(11):2729-36. Epub 2004 Aug 31.

PMID:
15340093
43.

Phagocytes transmit Chlamydia pneumoniae from the lungs to the vasculature.

Gieffers J, van Zandbergen G, Rupp J, Sayk F, Krüger S, Ehlers S, Solbach W, Maass M.

Eur Respir J. 2004 Apr;23(4):506-10.

44.

ANCA against the bactericidal/permeability increasing protein (BPI-ANCA) can compromise the antibiotic function of BPI in a Wegener's granulomatosis patient.

Schultz H, Heintz H, van Zandbergen G, Ullrich S, Reinhold-Keller E, Gross WL.

Clin Exp Rheumatol. 2003 Nov-Dec;21(6):763-6.

PMID:
14740457
45.

Chlamydia pneumoniae multiply in neutrophil granulocytes and delay their spontaneous apoptosis.

van Zandbergen G, Gieffers J, Kothe H, Rupp J, Bollinger A, Aga E, Klinger M, Brade H, Dalhoff K, Maass M, Solbach W, Laskay T.

J Immunol. 2004 Feb 1;172(3):1768-76.

46.

Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2.

Lotz S, Aga E, Wilde I, van Zandbergen G, Hartung T, Solbach W, Laskay T.

J Leukoc Biol. 2004 Mar;75(3):467-77. Epub 2003 Dec 12.

PMID:
14673018
47.

Neutrophil granulocytes--Trojan horses for Leishmania major and other intracellular microbes?

Laskay T, van Zandbergen G, Solbach W.

Trends Microbiol. 2003 May;11(5):210-4.

PMID:
12781523
49.

Inhibition of the spontaneous apoptosis of neutrophil granulocytes by the intracellular parasite Leishmania major.

Aga E, Katschinski DM, van Zandbergen G, Laufs H, Hansen B, Müller K, Solbach W, Laskay T.

J Immunol. 2002 Jul 15;169(2):898-905.

50.

Polarized expression of Tamm-Horsfall protein by renal tubular epithelial cells activates human granulocytes.

Kreft B, Jabs WJ, Laskay T, Klinger M, Solbach W, Kumar S, van Zandbergen G.

Infect Immun. 2002 May;70(5):2650-6.

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