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Antibiotic prescribing for common infections in UK general practice: variability and drivers.

Palin V, Mölter A, Belmonte M, Ashcroft DM, White A, Welfare W, van Staa T.

J Antimicrob Chemother. 2019 Apr 30. pii: dkz163. doi: 10.1093/jac/dkz163. [Epub ahead of print]


Term sets: A transparent and reproducible representation of clinical code sets.

Williams R, Brown B, Kontopantelis E, van Staa T, Peek N.

PLoS One. 2019 Feb 14;14(2):e0212291. doi: 10.1371/journal.pone.0212291. eCollection 2019.


The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex 'mix-and-match' implementation package.

Hays JP, Mitsakakis K, Luz S, van Belkum A, Becker K, van den Bruel A, Harbarth S, Rex JH, Simonsen GS, Werner G, Di Gregori V, Lüdke G, van Staa T, Moran-Gilad J, Bachmann TT; JPIAMR AMR-RDT consortium.

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1015-1022. doi: 10.1007/s10096-019-03492-4. Epub 2019 Feb 2. Review.


Relationship between prescribing of antibiotics and other medicines in primary care: a cross-sectional study.

Li Y, Mölter A, White A, Welfare W, Palin V, Belmonte M, Ashcroft DM, Sperrin M, van Staa TP.

Br J Gen Pract. 2019 Jan;69(678):e42-e51. doi: 10.3399/bjgp18X700457. Epub 2018 Dec 17.


Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data.

Kwakkenbos L, Juszczak E, Hemkens LG, Sampson M, Fröbert O, Relton C, Gale C, Zwarenstein M, Langan SM, Moher D, Boutron I, Ravaud P, Campbell MK, Mc Cord KA, van Staa TP, Thabane L, Uher R, Verkooijen HM, Benchimol EI, Erlinge D, Sauvé M, Torgerson D, Thombs BD.

Res Integr Peer Rev. 2018 Oct 29;3:9. doi: 10.1186/s41073-018-0053-3. eCollection 2018.


Study investigating the generalisability of a COPD trial based in primary care (Salford Lung Study) and the presence of a Hawthorne effect.

Pate A, Barrowman M, Webb D, Pimenta JM, Davis KJ, Williams R, Van Staa T, Sperrin M.

BMJ Open Respir Res. 2018 Oct 25;5(1):e000339. doi: 10.1136/bmjresp-2018-000339. eCollection 2018.


Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database.

Khalid S, Calderon-Larrañaga S, Hawley S, Ali MS, Judge A, Arden N, van Staa T, Cooper C, Javaid MK, Prieto-Alhambra D.

Clin Epidemiol. 2018 Oct 9;10:1417-1431. doi: 10.2147/CLEP.S164112. eCollection 2018.


Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records.

Joseph RM, Ray DW, Keevil B, van Staa TP, Dixon WG.

RMD Open. 2018 Oct 1;4(2):e000700. doi: 10.1136/rmdopen-2018-000700. eCollection 2018.


Exposure measurement error when assessing current glucocorticoid use using UK primary care electronic prescription data.

Joseph RM, van Staa TP, Lunt M, Abrahamowicz M, Dixon WG.

Pharmacoepidemiol Drug Saf. 2019 Feb;28(2):179-186. doi: 10.1002/pds.4649. Epub 2018 Sep 28.


The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study.

Robinson DE, van Staa TP, Dennison EM, Cooper C, Dixon WG.

Bone. 2018 Dec;117:83-90. doi: 10.1016/j.bone.2018.09.004. Epub 2018 Sep 13.


Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data.

Kwakkenbos L, Imran M, McCord KA, Sampson M, Fröbert O, Gale C, Hemkens LG, Langan SM, Moher D, Relton C, Zwarenstein M, Benchimol EI, Boutron I, Campbell MK, Erlinge D, Jawad S, Ravaud P, Rice DB, Sauve M, van Staa TP, Thabane L, Uher R, Verkooijen HM, Juszczak E, Thombs BD.

BMJ Open. 2018 Aug 5;8(8):e025266. doi: 10.1136/bmjopen-2018-025266.


Using marginal structural models to adjust for treatment drop-in when developing clinical prediction models.

Sperrin M, Martin GP, Pate A, Van Staa T, Peek N, Buchan I.

Stat Med. 2018 Dec 10;37(28):4142-4154. doi: 10.1002/sim.7913. Epub 2018 Aug 2.


Antibiotic prescribing patterns in general medical practices in England: Does area matter?

Mölter A, Belmonte M, Palin V, Mistry C, Sperrin M, White A, Welfare W, Van Staa T.

Health Place. 2018 Sep;53:10-16. doi: 10.1016/j.healthplace.2018.07.004. Epub 2018 Jul 19.


Cancer recording in patients with and without type 2 diabetes in the Clinical Practice Research Datalink primary care data and linked hospital admission data: a cohort study.

Williams R, van Staa TP, Gallagher AM, Hammad T, Leufkens HGM, de Vries F.

BMJ Open. 2018 May 26;8(5):e020827. doi: 10.1136/bmjopen-2017-020827.


Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies.

Pye SR, Sheppard T, Joseph RM, Lunt M, Girard N, Haas JS, Bates DW, Buckeridge DL, van Staa TP, Tamblyn R, Dixon WG.

Pharmacoepidemiol Drug Saf. 2018 Jul;27(7):781-788. doi: 10.1002/pds.4440. Epub 2018 Apr 17.


Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink.

de Jong HJI, Cohen Tervaert JW, Lalmohamed A, de Vries F, Vandebriel RJ, van Loveren H, Klungel OH, van Staa TP.

PLoS One. 2018 Feb 23;13(2):e0193297. doi: 10.1371/journal.pone.0193297. eCollection 2018.


Response to: 'Statins in systemic lupus erythematosus' by Abud-Mendoza.

de Jong HJI, van Staa TP, Cohen Tervaert JW.

Ann Rheum Dis. 2019 May;78(5):e43. doi: 10.1136/annrheumdis-2017-212902. Epub 2018 Jan 22. No abstract available.


The use of random-effects models to identify health care center-related characteristics modifying the effect of antipsychotic drugs.

Nordon C, Battin C, Verdoux H, Haro JM, Belger M, Abenhaim L, van Staa TP.

Clin Epidemiol. 2017 Dec 14;9:689-698. doi: 10.2147/CLEP.S145353. eCollection 2017.


Incidence and prevalence of hepatitis B in patients with diabetes mellitus in the UK: A population-based cohort study using the UK Clinical Practice Research Datalink.

Ferreira GLC, Marano C, De Moerlooze L, Guignard A, Feng Y, El Hahi Y, van Staa T.

J Viral Hepat. 2018 May;25(5):571-580. doi: 10.1111/jvh.12841. Epub 2018 Jan 17.


Risk of venous thromboembolism among users of different anti-osteoporosis drugs: a population-based cohort analysis including over 200,000 participants from Spain and the UK.

Martín-Merino E, Petersen I, Hawley S, Álvarez-Gutierrez A, Khalid S, Llorente-Garcia A, Delmestri A, Javaid MK, Van Staa TP, Judge A, Cooper C, Prieto-Alhambra D.

Osteoporos Int. 2018 Feb;29(2):467-478. doi: 10.1007/s00198-017-4308-5. Epub 2017 Dec 3.


Health Data for Public Health: Towards New Ways of Combining Data Sources to Support Research Efforts in Europe.

Burgun A, Bernal-Delgado E, Kuchinke W, van Staa T, Cunningham J, Lettieri E, Mazzali C, Oksen D, Estupiñan F, Barone A, Chène G.

Yearb Med Inform. 2017 Aug;26(1):235-240. doi: 10.15265/IY-2017-034. Epub 2017 Sep 11.


Supplementing electronic health records through sample collection and patient diaries: A study set within a primary care research database.

Joseph RM, Soames J, Wright M, Sultana K, van Staa TP, Dixon WG.

Pharmacoepidemiol Drug Saf. 2018 Feb;27(2):239-242. doi: 10.1002/pds.4323. Epub 2017 Sep 19.


Risk of community-acquired pneumonia in chronic obstructive pulmonary disease stratified by smoking status: a population-based cohort study in the United Kingdom.

Braeken DC, Rohde GG, Franssen FM, Driessen JH, van Staa TP, Souverein PC, Wouters EF, de Vries F.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 14;12:2425-2432. doi: 10.2147/COPD.S138435. eCollection 2017.


Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study.

Wing K, Bhaskaran K, Pealing L, Root A, Smeeth L, van Staa TP, Klungel OH, Reynolds RF, Douglas I.

J Antimicrob Chemother. 2017 Sep 1;72(9):2636-2646. doi: 10.1093/jac/dkx183.


Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study.

De Jong HJI, van Staa TP, Lalmohamed A, de Vries F, Vandebriel RJ, Van Loveren H, Klungel OH, Cohen Tervaert JW.

Ann Rheum Dis. 2017 Oct;76(10):1723-1730. doi: 10.1136/annrheumdis-2016-210936. Epub 2017 Jul 6.


A nationwide cohort study of slipped capital femoral epiphysis.

Perry DC, Metcalfe D, Costa ML, Van Staa T.

Arch Dis Child. 2017 Dec;102(12):1132-1136. doi: 10.1136/archdischild-2016-312328. Epub 2017 Jun 29.


Cost-effectiveness of antibiotics for COPD management: observational analysis using CPRD data.

Ronaldson SJ, Raghunath A, Torgerson DJ, Van Staa T.

ERJ Open Res. 2017 Jun 19;3(2). pii: 00085-2016. doi: 10.1183/23120541.00085-2016. eCollection 2017 Apr.


Epidemiology of alcohol dependence in UK primary care: Results from a large observational study using the Clinical Practice Research Datalink.

Thompson A, Wright AK, Ashcroft DM, van Staa TP, Pirmohamed M.

PLoS One. 2017 Mar 31;12(3):e0174818. doi: 10.1371/journal.pone.0174818. eCollection 2017.


Erratum to: Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study.

Candlish J, Pate A, Sperrin M, van Staa T; GetReal Work Package 2.

BMC Med Res Methodol. 2017 Mar 22;17(1):47. doi: 10.1186/s12874-017-0326-4. No abstract available.


Drug therapy for alcohol dependence in primary care in the UK: A Clinical Practice Research Datalink study.

Thompson A, Ashcroft DM, Owens L, van Staa TP, Pirmohamed M.

PLoS One. 2017 Mar 20;12(3):e0173272. doi: 10.1371/journal.pone.0173272. eCollection 2017.


Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study.

Candlish J, Pate A, Sperrin M, van Staa T; GetReal Work Package 2.

BMC Med Res Methodol. 2017 Jan 31;17(1):17. doi: 10.1186/s12874-017-0295-7. Erratum in: BMC Med Res Methodol. 2017 Mar 22;17 (1):47.


Better care through better use of data in GP-patient partnerships.

Brown B, Smeeth L, van Staa T, Buchan I.

Br J Gen Pract. 2017 Feb;67(655):54-55. doi: 10.3399/bjgp17X688921. No abstract available.


Frailty, prefrailty and employment outcomes in Health and Employment After Fifty (HEAF) Study.

Palmer KT, D'Angelo S, Harris EC, Linaker C, Gale CR, Evandrou M, Syddall H, van Staa T, Cooper C, Aihie Sayer A, Coggon D, Walker-Bone K.

Occup Environ Med. 2017 Jul;74(7):476-482. doi: 10.1136/oemed-2016-104103. Epub 2017 Jan 6.


Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study.

Palmer KT, D'Angelo S, Harris EC, Linaker C, Sayer AA, Gale CR, Evandrou M, van Staa T, Cooper C, Coggon D.

Scand J Work Environ Health. 2017 Mar 1;43(2):136-145. doi: 10.5271/sjweh.3618. Epub 2017 Jan 4.


Optimal design and patient selection for interventional trials using radiogenomic biomarkers: A REQUITE and Radiogenomics consortium statement.

De Ruysscher D, Defraene G, Ramaekers BLT, Lambin P, Briers E, Stobart H, Ward T, Bentzen SM, Van Staa T, Azria D, Rosenstein B, Kerns S, West C.

Radiother Oncol. 2016 Dec;121(3):440-446. doi: 10.1016/j.radonc.2016.11.003. Epub 2016 Dec 12. Review.


Trends in oral anti-osteoporosis drug prescription in the United Kingdom between 1990 and 2012: Variation by age, sex, geographic location and ethnicity.

van der Velde RY, Wyers CE, Teesselink E, Geusens PPMM, van den Bergh JPW, de Vries F, Cooper C, Harvey NC, van Staa TP.

Bone. 2017 Jan;94:50-55. doi: 10.1016/j.bone.2016.10.013. Epub 2016 Oct 11.


Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements.

Nielen JT, Dagnelie PC, Emans PJ, Veldhorst-Janssen N, Lalmohamed A, van Staa TP, Boonen AE, van den Bemt BJ, de Vries F.

Pharmacoepidemiol Drug Saf. 2016 Nov;25(11):1245-1252. doi: 10.1002/pds.4089. Epub 2016 Sep 4.


On epidemiology of fractures and variation with age and ethnicity.

Harvey NC, Curtis EM, van der Velde R, Moon RJ, van den Bergh JP, Geusens P, de Vries F, van Staa TP, Cooper C.

Bone. 2016 Dec;93:230-231. doi: 10.1016/j.bone.2016.07.011. Epub 2016 Jul 17. No abstract available.


The epidemiology of mortality after fracture in England: variation by age, sex, time, geographic location, and ethnicity.

Klop C, van Staa TP, Cooper C, Harvey NC, de Vries F.

Osteoporos Int. 2017 Jan;28(1):161-168. doi: 10.1007/s00198-016-3787-0. Epub 2016 Oct 8.


Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury.

Wing K, Bhaskaran K, Smeeth L, van Staa TP, Klungel OH, Reynolds RF, Douglas I.

BMJ Open. 2016 Sep 2;6(9):e012102. doi: 10.1136/bmjopen-2016-012102.


Cohort Multiple Randomised Controlled Trials (cmRCT) design: efficient but biased? A simulation study to evaluate the feasibility of the Cluster cmRCT design.

Pate A, Candlish J, Sperrin M, Van Staa TP; GetReal Work Package 2.

BMC Med Res Methodol. 2016 Aug 26;16(1):109. doi: 10.1186/s12874-016-0208-1.


Big health data: the need to earn public trust.

van Staa TP, Goldacre B, Buchan I, Smeeth L.

BMJ. 2016 Jul 14;354:i3636. doi: 10.1136/bmj.i3636. No abstract available.


Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data.

Matthews A, Herrett E, Gasparrini A, Van Staa T, Goldacre B, Smeeth L, Bhaskaran K.

BMJ. 2016 Jun 28;353:i3283. doi: 10.1136/bmj.i3283.


Statins and Risk of Lower Limb Revision Surgery: The Influence of Differences in Study Design Using Electronic Health Records From the United Kingdom and Denmark.

Lalmohamed A, van Staa TP, Vestergaard P, Leufkens HGM, de Boer A, Emans P, Cooper C, de Vries F.

Am J Epidemiol. 2016 Jul 1;184(1):58-66. doi: 10.1093/aje/kwv311. Epub 2016 Jun 16.


Secular trends in fracture incidence in the UK between 1990 and 2012.

van der Velde RY, Wyers CE, Curtis EM, Geusens PPMM, van den Bergh JPW, de Vries F, Cooper C, van Staa TP, Harvey NC.

Osteoporos Int. 2016 Nov;27(11):3197-3206. doi: 10.1007/s00198-016-3650-3. Epub 2016 Jun 9.


A review of the methods used to define glucocorticoid exposure and risk attribution when investigating the risk of fracture in a rheumatoid arthritis population.

Robinson DE, Dennison EM, Cooper C, van Staa TP, Dixon WG.

Bone. 2016 Sep;90:107-15. doi: 10.1016/j.bone.2016.06.001. Epub 2016 Jun 3. Review.


Reply: Comparing the ATRIA, CHADS2, and CHA2DS2-VASc Scores for Stroke Prediction in Atrial Fibrillation.

van den Ham HA, Klungel OH, Singer DE, Leufkens HGM, van Staa TP.

J Am Coll Cardiol. 2016 May 17;67(19):2317-2318. doi: 10.1016/j.jacc.2016.01.085. No abstract available.


Job dissatisfaction and the older worker: baseline findings from the Health and Employment After Fifty study.

D'Angelo S, Coggon D, Harris EC, Linaker C, Sayer AA, Gale CR, Evandrou M, van Staa T, Cooper C, Walker-Bone K, Palmer KT.

Occup Environ Med. 2016 Aug;73(8):512-9. doi: 10.1136/oemed-2016-103591. Epub 2016 May 5.


Insulin glargine use and breast cancer risk: Associations with cumulative exposure.

Peeters PJ, Bazelier MT, Leufkens HG, Auvinen A, van Staa TP, de Vries F, De Bruin ML.

Acta Oncol. 2016 Jul;55(7):851-8. doi: 10.3109/0284186X.2016.1155736. Epub 2016 May 6.

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