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Items: 48

1.

Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019.

Donaldson K, Buchanich JM, Grigson PS, Deneke E, Donaldson K, Vrana KE, Sacks DB, Kuehn GJ, Cardamone D, Pesce A, Smiley S, Nickley J, Krock K, Thomas R, Wilkerson ML, Farag HA, Challa SR, Tice AM, Wolk DM, Prichard J, Grant ML, Regmi S, Kerbacher B, Quinton LE, Farag HA, Tice AM, Wolk DM, Olson J, Haynes A, Yu E, McCully KS, Assi J, Wong M, Zarrin-Khameh N, Nifong TP, Hawker CD, Carlton GT, Rivera JM, Foulis PR, Zuraw A, Morlote D, Peker D, Reddy V, Harada S, Crutchfield C, Zander D, Barbhuiya MA, Pederson EC, Straub ML, Scott SC, Neibauer TL, Salter WF, Creer MH, Zhu Y, Bornhorst JA, Theobald JP, Algeciras-Schimnich A, Cao L, Knox J, Hardy R, Texas HJ, McGuire MF, Hunter RL, Brown RE, Hicks J, Hicks J, Cai Z, Brown RE, Ali Y, Cheng KC, Katz SR, Ding Y, Vanselow DJ, Yakovlev MA, Lin AY, Clark DP, Vargas P, Xin X, Copper JE, Canfield VA, Ang KC, Wang Y, Xiao X, De Carlo F, van Rossum DB, La Rivière PJ, Newell J, Hossler C, Roche M, Warrick J, Phaeton R, Kesterson J, Donaldson K, Myers C, Barrios R, Mintz P, Robyak K, Hamilton C, McGhee P, Pederson C, Straub M, Scott S, Neibauer T, Salter W, Creer M, Zhu Y, Hamilton C, Robyak K, McGhee P, Pederson C, Straub M, Scott S, Neibauer T, Salter W, Creer M, Zhu Y, Singh N, Morlote D, Vnencak-Jones C, Yemelyanova A, Harada S, Shah M, Moghadamtousi SZ, Lan C, Duose D, Hu P, Esquenazi Y, Luthra R, Ballester LY, Koenig AN, Liu CG, Zhang J, Kalia A, Al-Habib A, Van Arsdall M, Dhingra S, Patel K, Tatevian N.

Ann Clin Lab Sci. 2019 May;49(3):403-416. No abstract available.

PMID:
31308044
2.

Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography.

Ding Y, Vanselow DJ, Yakovlev MA, Katz SR, Lin AY, Clark DP, Vargas P, Xin X, Copper JE, Canfield VA, Ang KC, Wang Y, Xiao X, De Carlo F, van Rossum DB, La Riviere P, Cheng KC.

Elife. 2019 May 7;8. pii: e44898. doi: 10.7554/eLife.44898.

3.

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography.

Lin AY, Ding Y, Vanselow DJ, Katz SR, Yakovlev MA, Clark DP, Mandrell D, Copper JE, van Rossum DB, Cheng KC.

J Vis Exp. 2018 Oct 17;(140). doi: 10.3791/58293.

4.

The S6 gate in regulatory Kv6 subunits restricts heteromeric K+ channel stoichiometry.

Pisupati A, Mickolajczyk KJ, Horton W, van Rossum DB, Anishkin A, Chintapalli SV, Li X, Chu-Luo J, Busey G, Hancock WO, Jegla T.

J Gen Physiol. 2018 Dec 3;150(12):1702-1721. doi: 10.1085/jgp.201812121. Epub 2018 Oct 15.

5.

FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome.

Caraveo G, Soste M, Cappelleti V, Fanning S, van Rossum DB, Whitesell L, Huang Y, Chung CY, Baru V, Zaichick S, Picotti P, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11313-E11322. doi: 10.1073/pnas.1711926115. Epub 2017 Dec 11.

6.

Comparative analysis of fixation and embedding techniques for optimized histological preparation of zebrafish.

Copper JE, Budgeon LR, Foutz CA, van Rossum DB, Vanselow DJ, Hubley MJ, Clark DP, Mandrell DT, Cheng KC.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Jun;208:38-46. doi: 10.1016/j.cbpc.2017.11.003. Epub 2017 Nov 20.

7.

Bilaterian Giant Ankyrins Have a Common Evolutionary Origin and Play a Conserved Role in Patterning the Axon Initial Segment.

Jegla T, Nguyen MM, Feng C, Goetschius DJ, Luna E, van Rossum DB, Kamel B, Pisupati A, Milner ES, Rolls MM.

PLoS Genet. 2016 Dec 2;12(12):e1006457. doi: 10.1371/journal.pgen.1006457. eCollection 2016 Dec.

8.

Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin.

Chintapalli SV, Jayanthi S, Mallipeddi PL, Gundampati R, Suresh Kumar TK, van Rossum DB, Anishkin A, Adams SH.

J Biol Chem. 2016 Nov 25;291(48):25133-25143. Epub 2016 Oct 7.

9.

Identification of Respiratory Syncytial Virus Nonstructural Protein 2 Residues Essential for Exploitation of the Host Ubiquitin System and Inhibition of Innate Immune Responses.

Whelan JN, Tran KC, van Rossum DB, Teng MN.

J Virol. 2016 Jun 24;90(14):6453-6463. doi: 10.1128/JVI.00423-16. Print 2016 Jul 15.

10.

Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of Ih.

Baker EC, Layden MJ, van Rossum DB, Kamel B, Medina M, Simpson E, Jegla T.

PLoS One. 2015 Nov 10;10(11):e0142730. doi: 10.1371/journal.pone.0142730. eCollection 2015.

11.

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.

Li X, Anishkin A, Liu H, van Rossum DB, Chintapalli SV, Sassic JK, Gallegos D, Pivaroff-Ward K, Jegla T.

J Gen Physiol. 2015 Nov;146(5):357-74. doi: 10.1085/jgp.201511491.

12.

Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin.

Chintapalli SV, Bhardwaj G, Patel R, Shah N, Patterson RL, van Rossum DB, Anishkin A, Adams SH.

PLoS One. 2015 Jun 1;10(6):e0128496. doi: 10.1371/journal.pone.0128496. eCollection 2015.

13.

Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans.

Li X, Liu H, Chu Luo J, Rhodes SA, Trigg LM, van Rossum DB, Anishkin A, Diatta FH, Sassic JK, Simmons DK, Kamel B, Medina M, Martindale MQ, Jegla T.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E1010-9. doi: 10.1073/pnas.1422941112. Epub 2015 Feb 17.

14.

The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release.

Hedgepeth SC, Garcia MI, Wagner LE 2nd, Rodriguez AM, Chintapalli SV, Snyder RR, Hankins GD, Henderson BR, Brodie KM, Yule DI, van Rossum DB, Boehning D.

J Biol Chem. 2015 Mar 13;290(11):7304-13. doi: 10.1074/jbc.M114.611186. Epub 2015 Feb 2.

15.

TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour.

Lindy AS, Parekh PK, Zhu R, Kanju P, Chintapalli SV, Tsvilovskyy V, Patterson RL, Anishkin A, van Rossum DB, Liedtke WB.

Nat Commun. 2014 Sep 2;5:4734. doi: 10.1038/ncomms5734.

16.

Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr.

Martinson AS, van Rossum DB, Diatta FH, Layden MJ, Rhodes SA, Martindale MQ, Jegla T.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5712-7. doi: 10.1073/pnas.1321716111. Epub 2014 Mar 31.

17.

Reevaluation of the evolutionary events within recA/RAD51 phylogeny.

Chintapalli SV, Bhardwaj G, Babu J, Hadjiyianni L, Hong Y, Todd GK, Boosalis CA, Zhang Z, Zhou X, Ma H, Anishkin A, van Rossum DB, Patterson RL.

BMC Genomics. 2013 Apr 10;14:240. doi: 10.1186/1471-2164-14-240.

18.

PHYRN: a robust method for phylogenetic analysis of highly divergent sequences.

Bhardwaj G, Ko KD, Hong Y, Zhang Z, Ho NL, Chintapalli SV, Kline LA, Gotlin M, Hartranft DN, Patterson ME, Dave F, Smith EJ, Holmes EC, Patterson RL, van Rossum DB.

PLoS One. 2012;7(4):e34261. doi: 10.1371/journal.pone.0034261. Epub 2012 Apr 13.

19.

Exploring phospholipase C-coupled Ca(2+) signalling networks using Boolean modelling.

Bhardwaj G, Wells CP, Albert R, van Rossum DB, Patterson RL.

IET Syst Biol. 2011 May;5(3):174-84. doi: 10.1049/iet-syb.2010.0019.

PMID:
21639591
20.

Conserved GXXXG- and S/T-like motifs in the transmembrane domains of NS4B protein are required for hepatitis C virus replication.

Han Q, Aligo J, Manna D, Belton K, Chintapalli SV, Hong Y, Patterson RL, van Rossum DB, Konan KV.

J Virol. 2011 Jul;85(13):6464-79. doi: 10.1128/JVI.02298-10. Epub 2011 Apr 20.

21.

Adaptive GDDA-BLAST: fast and efficient algorithm for protein sequence embedding.

Hong Y, Kang J, Lee D, van Rossum DB.

PLoS One. 2010 Oct 22;5(10):e13596. doi: 10.1371/journal.pone.0013596.

22.

TRPC channels in pheromone sensing.

Kiselyov K, van Rossum DB, Patterson RL.

Vitam Horm. 2010;83:197-213. doi: 10.1016/S0083-6729(10)83008-0. Review.

PMID:
20831947
23.

Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion.

Hoque KM, Woodward OM, van Rossum DB, Zachos NC, Chen L, Leung GP, Guggino WB, Guggino SE, Tse CM.

J Gen Physiol. 2010 Jan;135(1):43-58. doi: 10.1085/jgp.200910339.

24.

Phylogenetic Profiles Reveal Structural and Functional Determinants of Lipid-binding.

Hong Y, Chalkia D, Ko KD, Bhardwaj G, Chang GS, van Rossum DB, Patterson RL.

J Proteomics Bioinform. 2009 Mar 21;2:139-149.

25.

Phylogenetic profiles reveal structural/functional determinants of TRPC3 signal-sensing antennae.

Ko KD, Bhardwaj G, Hong Y, Chang GS, Kiselyov K, van Rossum DB, Patterson RL.

Commun Integr Biol. 2009;2(2):133-7.

26.

Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Zachos NC, van Rossum DB, Li X, Caraveo G, Sarker R, Cha B, Mohan S, Desiderio S, Patterson RL, Donowitz M.

J Biol Chem. 2009 Jul 17;284(29):19437-44. doi: 10.1074/jbc.M109.006098. Epub 2009 May 27.

27.

PKC and PLA2: probing the complexities of the calcium network.

van Rossum DB, Patterson RL.

Cell Calcium. 2009 Jun;45(6):535-45. doi: 10.1016/j.ceca.2009.02.008. Epub 2009 Apr 5. Review.

PMID:
19345415
28.

Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition.

Mustafa AK, van Rossum DB, Patterson RL, Maag D, Ehmsen JT, Gazi SK, Chakraborty A, Barrow RK, Amzel LM, Snyder SH.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2921-6. doi: 10.1073/pnas.0813105106. Epub 2009 Feb 4.

29.

TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion.

van Rossum DB, Oberdick D, Rbaibi Y, Bhardwaj G, Barrow RK, Nikolaidis N, Snyder SH, Kiselyov K, Patterson RL.

J Biol Chem. 2008 Dec 5;283(49):34384-92. doi: 10.1074/jbc.M804707200. Epub 2008 Sep 29.

30.

Phylogenetic profiles reveal evolutionary relationships within the "twilight zone" of sequence similarity.

Chang GS, Hong Y, Ko KD, Bhardwaj G, Holmes EC, Patterson RL, van Rossum DB.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13474-9. doi: 10.1073/pnas.0803860105. Epub 2008 Sep 2.

31.

HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.

Chakraborty A, Koldobskiy MA, Sixt KM, Juluri KR, Mustafa AK, Snowman AM, van Rossum DB, Patterson RL, Snyder SH.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1134-9. doi: 10.1073/pnas.0711168105. Epub 2008 Jan 14.

32.

Ancient origin of the new developmental superfamily DANGER.

Nikolaidis N, Chalkia D, Watkins DN, Barrow RK, Snyder SH, van Rossum DB, Patterson RL.

PLoS One. 2007 Feb 14;2(2):e204.

33.

Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.

Caraveo G, van Rossum DB, Patterson RL, Snyder SH, Desiderio S.

Science. 2006 Oct 6;314(5796):122-5.

34.

DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity.

van Rossum DB, Patterson RL, Cheung KH, Barrow RK, Syrovatkina V, Gessell GS, Burkholder SG, Watkins DN, Foskett JK, Snyder SH.

J Biol Chem. 2006 Dec 1;281(48):37111-6. Epub 2006 Sep 21.

35.

Association of small ankyrin 1 with the sarcoplasmic reticulum.

Porter NC, Resneck WG, O'Neill A, Van Rossum DB, Stone MR, Bloch RJ.

Mol Membr Biol. 2005 Sep-Oct;22(5):421-32.

PMID:
16308276
36.

Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling.

Patterson RL, van Rossum DB, Nikolaidis N, Gill DL, Snyder SH.

Trends Biochem Sci. 2005 Dec;30(12):688-97. Epub 2005 Nov 2. Review.

PMID:
16260143
37.

Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain.

van Rossum DB, Patterson RL, Sharma S, Barrow RK, Kornberg M, Gill DL, Snyder SH.

Nature. 2005 Mar 3;434(7029):99-104.

PMID:
15744307
38.

Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH.

Patterson RL, van Rossum DB, Kaplin AI, Barrow RK, Snyder SH.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1357-9. Epub 2005 Jan 26.

39.

A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways.

Boehning D, van Rossum DB, Patterson RL, Snyder SH.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1466-71. Epub 2005 Jan 21.

40.

Calcium entry mediated by SOCs and TRP channels: variations and enigma.

Spassova MA, Soboloff J, He LP, Hewavitharana T, Xu W, Venkatachalam K, van Rossum DB, Patterson RL, Gill DL.

Biochim Biophys Acta. 2004 Dec 6;1742(1-3):9-20. Review.

41.

RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release.

Patterson RL, van Rossum DB, Barrow RK, Snyder SH.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2328-32.

42.

Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition.

van Rossum DB, Patterson RL, Kiselyov K, Boehning D, Barrow RK, Gill DL, Snyder SH.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2323-7.

43.

Obscurin is a ligand for small ankyrin 1 in skeletal muscle.

Kontrogianni-Konstantopoulos A, Jones EM, Van Rossum DB, Bloch RJ.

Mol Biol Cell. 2003 Mar;14(3):1138-48.

44.

Phospholipase C-gamma is required for agonist-induced Ca2+ entry.

Patterson RL, van Rossum DB, Ford DL, Hurt KJ, Bae SS, Suh PG, Kurosaki T, Snyder SH, Gill DL.

Cell. 2002 Nov 15;111(4):529-41.

45.

The cellular and molecular basis of store-operated calcium entry.

Venkatachalam K, van Rossum DB, Patterson RL, Ma HT, Gill DL.

Nat Cell Biol. 2002 Nov;4(11):E263-72. Review.

PMID:
12415286
46.

Ca2+ entry mediated by store depletion, S-nitrosylation, and TRP3 channels. Comparison of coupling and function.

van Rossum DB, Patterson RL, Ma HT, Gill DL.

J Biol Chem. 2000 Sep 15;275(37):28562-8.

47.

Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels.

Ma HT, Patterson RL, van Rossum DB, Birnbaumer L, Mikoshiba K, Gill DL.

Science. 2000 Mar 3;287(5458):1647-51.

48.

Store-operated Ca2+ entry: evidence for a secretion-like coupling model.

Patterson RL, van Rossum DB, Gill DL.

Cell. 1999 Aug 20;98(4):487-99.

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