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Items: 1 to 50 of 858

1.

Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia.

Preston JA, Bewley MA, Marriott HM, Houghton AM, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, Whyte MKB, Shapiro SD, Dockrell DH.

Am J Respir Crit Care Med. 2019 Jan 16. doi: 10.1164/rccm.201804-0646OC. [Epub ahead of print]

2.

Casein kinase-II inhibition promotes retinal ganglion cell survival and axonal regeneration.

Cen LP, Liu YF, Ng TK, Luo JM, van Rooijen N, Zhang M, Pang CP, Cui Q.

Exp Eye Res. 2018 Dec;177:153-159. doi: 10.1016/j.exer.2018.08.010. Epub 2018 Aug 15.

PMID:
30118655
3.

TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.

Bird TG, Müller M, Boulter L, Vincent DF, Ridgway RA, Lopez-Guadamillas E, Lu WY, Jamieson T, Govaere O, Campbell AD, Ferreira-Gonzalez S, Cole AM, Hay T, Simpson KJ, Clark W, Hedley A, Clarke M, Gentaz P, Nixon C, Bryce S, Kiourtis C, Sprangers J, Nibbs RJB, Van Rooijen N, Bartholin L, McGreal SR, Apte U, Barry ST, Iredale JP, Clarke AR, Serrano M, Roskams TA, Sansom OJ, Forbes SJ.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaan1230. doi: 10.1126/scitranslmed.aan1230.

PMID:
30111642
4.

Malt1 blocks IL-1β production by macrophages in vitro and limits dextran sodium sulfate-induced intestinal inflammation in vivo.

Monajemi M, Pang YCF, Bjornson S, Menzies SC, van Rooijen N, Sly LM.

J Leukoc Biol. 2018 Sep;104(3):557-572. doi: 10.1002/JLB.3VMA0118-019R. Epub 2018 Jun 14.

PMID:
29901822
5.

TRAIL-Dependent Resolution of Pulmonary Fibrosis.

Habiel DM, Moreira AP, Ismailoglu UB, Dunleavy MP, Cavassani KA, van Rooijen N, Coelho AL, Hogaboam CM.

Mediators Inflamm. 2018 Jan 24;2018:7934362. doi: 10.1155/2018/7934362. eCollection 2018.

6.

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

Turner JD, Pionnier N, Furlong-Silva J, Sjoberg H, Cross S, Halliday A, Guimaraes AF, Cook DAN, Steven A, Van Rooijen N, Allen JE, Jenkins SJ, Taylor MJ.

PLoS Pathog. 2018 Mar 16;14(3):e1006949. doi: 10.1371/journal.ppat.1006949. eCollection 2018 Mar.

7.

Macrophage-dependent impairment of α2-adrenergic autoreceptor inhibition of Ca2+ channels in sympathetic neurons from DOCA-salt but not high-fat diet-induced hypertensive rats.

Mui RK, Fernandes RN, Garver HG, Van Rooijen N, Galligan JJ.

Am J Physiol Heart Circ Physiol. 2018 Apr 1;314(4):H863-H877. doi: 10.1152/ajpheart.00536.2017. Epub 2018 Jan 5.

PMID:
29351460
8.

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection.

Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA.

J Virol. 2018 Jan 17;92(3). pii: e01637-17. doi: 10.1128/JVI.01637-17. Print 2018 Feb 1.

9.

A systemic macrophage response is required to contain a peripheral poxvirus infection.

Davies ML, Parekh NJ, Kaminsky LW, Soni C, Reider IE, Krouse TE, Fischer MA, van Rooijen N, Rahman ZSM, Norbury CC.

PLoS Pathog. 2017 Jun 14;13(6):e1006435. doi: 10.1371/journal.ppat.1006435. eCollection 2017 Jun.

10.

Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection.

Lee AJ, Chen B, Chew MV, Barra NG, Shenouda MM, Nham T, van Rooijen N, Jordana M, Mossman KL, Schreiber RD, Mack M, Ashkar AA.

J Exp Med. 2017 Apr 3;214(4):1153-1167. doi: 10.1084/jem.20160880. Epub 2017 Mar 6.

11.

F4/80+ Host Macrophages Are a Barrier to Murine Embryonic Stem Cell-Derived Hematopoietic Progenitor Engraftment In Vivo.

Thompson HL, van Rooijen N, McLelland BT, Manilay JO.

J Immunol Res. 2016;2016:2414906. Epub 2016 Oct 30.

12.

Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension.

Faraco G, Sugiyama Y, Lane D, Garcia-Bonilla L, Chang H, Santisteban MM, Racchumi G, Murphy M, Van Rooijen N, Anrather J, Iadecola C.

J Clin Invest. 2016 Dec 1;126(12):4674-4689. doi: 10.1172/JCI86950. Epub 2016 Nov 14.

13.

Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum.

Piao X, Yamazaki S, Komazawa-Sakon S, Miyake S, Nakabayashi O, Kurosawa T, Mikami T, Tanaka M, Van Rooijen N, Ohmuraya M, Oikawa A, Kojima Y, Kakuta S, Uchiyama Y, Tanaka M, Nakano H.

Hepatology. 2017 Jan;65(1):237-252. doi: 10.1002/hep.28878. Epub 2016 Nov 25.

PMID:
27770461
14.

Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance.

van Leeuwen MA, Costes LMM, van Berkel LA, Simons-Oosterhuis Y, du Pré MF, Kozijn AE, Raatgeep HC, Lindenbergh-Kortleve DJ, van Rooijen N, Koning F, Samsom JN.

Mucosal Immunol. 2017 May;10(3):635-649. doi: 10.1038/mi.2016.76. Epub 2016 Aug 31.

PMID:
27579860
15.

Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice.

Gillis CM, Jönsson F, Mancardi DA, Tu N, Beutier H, Van Rooijen N, Macdonald LE, Murphy AJ, Bruhns P.

J Allergy Clin Immunol. 2017 Apr;139(4):1253-1265.e14. doi: 10.1016/j.jaci.2016.06.058. Epub 2016 Aug 24.

16.

IgG subclasses determine pathways of anaphylaxis in mice.

Beutier H, Gillis CM, Iannascoli B, Godon O, England P, Sibilano R, Reber LL, Galli SJ, Cragg MS, Van Rooijen N, Mancardi DA, Bruhns P, Jönsson F.

J Allergy Clin Immunol. 2017 Jan;139(1):269-280.e7. doi: 10.1016/j.jaci.2016.03.028. Epub 2016 Apr 26.

17.

Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression.

Galletti G, Scielzo C, Barbaglio F, Rodriguez TV, Riba M, Lazarevic D, Cittaro D, Simonetti G, Ranghetti P, Scarfò L, Ponzoni M, Rocchi M, Corti A, Anselmo A, van Rooijen N, Klein C, Ries CH, Ghia P, De Palma M, Caligaris-Cappio F, Bertilaccio MTS.

Cell Rep. 2016 Feb 23;14(7):1748-1760. doi: 10.1016/j.celrep.2016.01.042. Epub 2016 Feb 11.

18.

Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets.

Hitchcock JR, Cook CN, Bobat S, Ross EA, Flores-Langarica A, Lowe KL, Khan M, Dominguez-Medina CC, Lax S, Carvalho-Gaspar M, Hubscher S, Rainger GE, Cobbold M, Buckley CD, Mitchell TJ, Mitchell A, Jones ND, Van Rooijen N, Kirchhofer D, Henderson IR, Adams DH, Watson SP, Cunningham AF.

J Clin Invest. 2015 Dec;125(12):4429-46. doi: 10.1172/JCI79070. Epub 2015 Nov 16.

19.

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.

Shaw TN, Stewart-Hutchinson PJ, Strangward P, Dandamudi DB, Coles JA, Villegas-Mendez A, Gallego-Delgado J, van Rooijen N, Zindy E, Rodriguez A, Brewer JM, Couper KN, Dustin ML.

PLoS Pathog. 2015 Nov 12;11(11):e1005210. doi: 10.1371/journal.ppat.1005210. eCollection 2015.

20.

Macrophages in bone fracture healing: Their essential role in endochondral ossification.

Schlundt C, El Khassawna T, Serra A, Dienelt A, Wendler S, Schell H, van Rooijen N, Radbruch A, Lucius R, Hartmann S, Duda GN, Schmidt-Bleek K.

Bone. 2018 Jan;106:78-89. doi: 10.1016/j.bone.2015.10.019. Epub 2015 Oct 31.

PMID:
26529389
21.

Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease.

Ngoh EN, Weisser SB, Lo Y, Kozicky LK, Jen R, Brugger HK, Menzies SC, McLarren KW, Nackiewicz D, van Rooijen N, Jacobson K, Ehses JA, Turvey SE, Sly LM.

Gastroenterology. 2016 Feb;150(2):465-76. doi: 10.1053/j.gastro.2015.09.049. Epub 2015 Oct 19.

PMID:
26481854
22.

Pulmonary Chlamydia muridarum challenge activates lung interstitial macrophages which correlate with IFN-γ production and infection control in mice.

Gracey E, Baglaenko Y, Prayitno N, Van Rooijen N, Akram A, Lin A, Chiu B, Inman RD.

Eur J Immunol. 2015 Dec;45(12):3417-30. doi: 10.1002/eji.201545874. Epub 2015 Sep 28.

23.

Hyperglycemia and PPARγ Antagonistically Influence Macrophage Polarization and Infarct Healing After Ischemic Stroke.

Gliem M, Klotz L, van Rooijen N, Hartung HP, Jander S.

Stroke. 2015 Oct;46(10):2935-42. doi: 10.1161/STROKEAHA.115.010557. Epub 2015 Sep 3.

PMID:
26337971
24.

Macrophage depletion lowers blood pressure and restores sympathetic nerve α2-adrenergic receptor function in mesenteric arteries of DOCA-salt hypertensive rats.

Thang LV, Demel SL, Crawford R, Kaminski NE, Swain GM, Van Rooijen N, Galligan JJ.

Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1186-97. doi: 10.1152/ajpheart.00283.2015. Epub 2015 Aug 28.

25.

Mechanism of microglia neuroprotection: Involvement of P2X7, TNFα, and valproic acid.

Masuch A, Shieh CH, van Rooijen N, van Calker D, Biber K.

Glia. 2016 Jan;64(1):76-89. doi: 10.1002/glia.22904. Epub 2015 Aug 21.

PMID:
26295445
26.

CD68 acts as a major gateway for malaria sporozoite liver infection.

Cha SJ, Park K, Srinivasan P, Schindler CW, van Rooijen N, Stins M, Jacobs-Lorena M.

J Exp Med. 2015 Aug 24;212(9):1391-403. doi: 10.1084/jem.20110575. Epub 2015 Jul 27.

27.

Macrophages Subvert Adaptive Immunity to Urinary Tract Infection.

Mora-Bau G, Platt AM, van Rooijen N, Randolph GJ, Albert ML, Ingersoll MA.

PLoS Pathog. 2015 Jul 16;11(7):e1005044. doi: 10.1371/journal.ppat.1005044. eCollection 2015 Jul.

28.

Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regeneration.

Elsegood CL, Chan CW, Degli-Esposti MA, Wikstrom ME, Domenichini A, Lazarus K, van Rooijen N, Ganss R, Olynyk JK, Yeoh GC.

Hepatology. 2015 Oct;62(4):1272-84. doi: 10.1002/hep.27977. Epub 2015 Jul 31.

PMID:
26173184
29.

Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke.

Gliem M, Krammes K, Liaw L, van Rooijen N, Hartung HP, Jander S.

Glia. 2015 Dec;63(12):2198-207. doi: 10.1002/glia.22885. Epub 2015 Jul 7.

PMID:
26148976
30.

Exercise promotes collateral artery growth mediated by monocytic nitric oxide.

Schirmer SH, Millenaar DN, Werner C, Schuh L, Degen A, Bettink SI, Lipp P, van Rooijen N, Meyer T, Böhm M, Laufs U.

Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1862-71. doi: 10.1161/ATVBAHA.115.305806. Epub 2015 Jun 18.

PMID:
26088573
31.

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract.

Fougeron D, Van Maele L, Songhet P, Cayet D, Hot D, Van Rooijen N, Mollenkopf HJ, Hardt WD, Benecke AG, Sirard JC.

Vaccine. 2015 Jun 26;33(29):3331-41. doi: 10.1016/j.vaccine.2015.05.022. Epub 2015 May 21.

PMID:
26003491
32.

Myofiber damage precedes macrophage infiltration after in vivo injury in dysferlin-deficient A/J mouse skeletal muscle.

Roche JA, Tulapurkar ME, Mueller AL, van Rooijen N, Hasday JD, Lovering RM, Bloch RJ.

Am J Pathol. 2015 Jun;185(6):1686-98. doi: 10.1016/j.ajpath.2015.02.020. Epub 2015 Apr 25.

33.

Specific depletion of Ly6C(hi) inflammatory monocytes prevents immunopathology in experimental cerebral malaria.

Schumak B, Klocke K, Kuepper JM, Biswas A, Djie-Maletz A, Limmer A, van Rooijen N, Mack M, Hoerauf A, Dunay IR.

PLoS One. 2015 Apr 17;10(4):e0124080. doi: 10.1371/journal.pone.0124080. eCollection 2015.

34.

The role of CD1d-restricted NKT cells in the clearance of Pseudomonas aeruginosa from the lung is dependent on the host genetic background.

Benoit P, Sigounas VY, Thompson JL, van Rooijen N, Poynter ME, Wargo MJ, Boyson JE.

Infect Immun. 2015 Jun;83(6):2557-65. doi: 10.1128/IAI.00015-15. Epub 2015 Apr 13.

35.

Liver inflammation abrogates immunological tolerance induced by Kupffer cells.

Heymann F, Peusquens J, Ludwig-Portugall I, Kohlhepp M, Ergen C, Niemietz P, Martin C, van Rooijen N, Ochando JC, Randolph GJ, Luedde T, Ginhoux F, Kurts C, Trautwein C, Tacke F.

Hepatology. 2015 Jul;62(1):279-91. doi: 10.1002/hep.27793. Epub 2015 Apr 22.

PMID:
25810240
36.

Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma.

Ford CA, Petrova S, Pound JD, Voss JJ, Melville L, Paterson M, Farnworth SL, Gallimore AM, Cuff S, Wheadon H, Dobbin E, Ogden CA, Dumitriu IE, Dunbar DR, Murray PG, Ruckerl D, Allen JE, Hume DA, van Rooijen N, Goodlad JR, Freeman TC, Gregory CD.

Curr Biol. 2015 Mar 2;25(5):577-88. doi: 10.1016/j.cub.2014.12.059. Epub 2015 Feb 19.

37.

von Willebrand factor arginine 1205 substitution results in accelerated macrophage-dependent clearance in vivo.

Rawley O, O'Sullivan JM, Chion A, Keyes S, Lavin M, van Rooijen N, Brophy TM, Fallon P, Preston RJ, O'Donnell JS.

J Thromb Haemost. 2015 May;13(5):821-6. doi: 10.1111/jth.12875. Epub 2015 Apr 13.

38.

WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.

Boulter L, Guest RV, Kendall TJ, Wilson DH, Wojtacha D, Robson AJ, Ridgway RA, Samuel K, Van Rooijen N, Barry ST, Wigmore SJ, Sansom OJ, Forbes SJ.

J Clin Invest. 2015 Mar 2;125(3):1269-85. doi: 10.1172/JCI76452. Epub 2015 Feb 17.

39.

Importance of bacterial replication and alveolar macrophage-independent clearance mechanisms during early lung infection with Streptococcus pneumoniae.

Camberlein E, Cohen JM, José R, Hyams CJ, Callard R, Chimalapati S, Yuste J, Edwards LA, Marshall H, van Rooijen N, Noursadeghi M, Brown JS.

Infect Immun. 2015 Mar;83(3):1181-9. doi: 10.1128/IAI.02788-14. Epub 2015 Jan 12.

40.

Splenic B cells from Hymenolepis diminuta-infected mice ameliorate colitis independent of T cells and via cooperation with macrophages.

Reyes JL, Wang A, Fernando MR, Graepel R, Leung G, van Rooijen N, Sigvardsson M, McKay DM.

J Immunol. 2015 Jan 1;194(1):364-78. doi: 10.4049/jimmunol.1400738. Epub 2014 Dec 1.

41.

Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response.

Houthuijzen JM, Daenen LG, Roodhart JM, Oosterom I, van Jaarsveld MT, Govaert KM, Smith ME, Sadatmand SJ, Rosing H, Kruse F, Helms BJ, van Rooijen N, Beijnen JH, Haribabu B, van de Lest CH, Voest EE.

Nat Commun. 2014 Nov 12;5:5275. doi: 10.1038/ncomms6275.

PMID:
25387467
42.

Clodronate treatment significantly depletes macrophages in chickens.

Kameka AM, Haddadi S, Jamaldeen FJ, Moinul P, He XT, Nawazdeen FH, Bonfield S, Sharif S, van Rooijen N, Abdul-Careem MF.

Can J Vet Res. 2014 Oct;78(4):274-82.

43.

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.

Bosmann M, Russkamp NF, Strobl B, Roewe J, Balouzian L, Pache F, Radsak MP, van Rooijen N, Zetoune FS, Sarma JV, Núñez G, Müller M, Murray PJ, Ward PA.

J Immunol. 2014 Dec 1;193(11):5668-77. doi: 10.4049/jimmunol.1302280. Epub 2014 Oct 27.

44.

Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing.

Bellner L, Marrazzo G, van Rooijen N, Dunn MW, Abraham NG, Schwartzman ML.

FASEB J. 2015 Jan;29(1):105-15. doi: 10.1096/fj.14-256503. Epub 2014 Oct 23.

45.

Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization.

Domínguez-Soto A, de las Casas-Engel M, Bragado R, Medina-Echeverz J, Aragoneses-Fenoll L, Martín-Gayo E, van Rooijen N, Berraondo P, Toribio ML, Moro MA, Cuartero I, Castrillo A, Sancho D, Sánchez-Torres C, Bruhns P, Sánchez-Ramón S, Corbí AL.

J Immunol. 2014 Nov 15;193(10):5181-9. doi: 10.4049/jimmunol.1303375. Epub 2014 Oct 17.

46.

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein.

Schepens B, Sedeyn K, Vande Ginste L, De Baets S, Schotsaert M, Roose K, Houspie L, Van Ranst M, Gilbert B, van Rooijen N, Fiers W, Piedra P, Saelens X.

EMBO Mol Med. 2014 Nov;6(11):1436-54. doi: 10.15252/emmm.201404005.

47.

Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma.

Zasłona Z, Przybranowski S, Wilke C, van Rooijen N, Teitz-Tennenbaum S, Osterholzer JJ, Wilkinson JE, Moore BB, Peters-Golden M.

J Immunol. 2014 Oct 15;193(8):4245-53. doi: 10.4049/jimmunol.1400580. Epub 2014 Sep 15.

48.

Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells.

Sarkar S, Döring A, Zemp FJ, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, Cairncross G, Weiss S, Yong VW.

Ann Neurosci. 2013 Oct;20(4):154. doi: 10.5214/ans.0972.7531.200407. No abstract available.

49.

Arginase activity in alternatively activated macrophages protects PI3Kp110δ deficient mice from dextran sodium sulfate induced intestinal inflammation.

Weisser SB, Kozicky LK, Brugger HK, Ngoh EN, Cheung B, Jen R, Menzies SC, Samarakoon A, Murray PJ, Lim CJ, Johnson P, Boucher JL, van Rooijen N, Sly LM.

Eur J Immunol. 2014 Nov;44(11):3353-67. doi: 10.1002/eji.201343981. Epub 2014 Sep 25.

50.

Macrophage depletion abates Porphyromonas gingivalis-induced alveolar bone resorption in mice.

Lam RS, O'Brien-Simpson NM, Lenzo JC, Holden JA, Brammar GC, Walsh KA, McNaughtan JE, Rowler DK, Van Rooijen N, Reynolds EC.

J Immunol. 2014 Sep 1;193(5):2349-62. doi: 10.4049/jimmunol.1400853. Epub 2014 Jul 28.

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