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Items: 1 to 50 of 108

1.

Sex Differences in Science: Do We Have a Problem?

van Rooij E, Bishopric NH.

JACC Basic Transl Sci. 2019 Aug 26;4(4):478-479. doi: 10.1016/j.jacbts.2019.07.007. eCollection 2019 Aug. No abstract available.

2.

Turning basic science discoveries into successful commercial opportunities.

van Rooij E.

Cardiovasc Res. 2019 Jul 31. pii: cvz172. doi: 10.1093/cvr/cvz172. [Epub ahead of print] No abstract available.

PMID:
31364701
3.

CRISPR Craze to Transform Cardiac Biology.

van Kampen SJ, van Rooij E.

Trends Mol Med. 2019 Sep;25(9):791-802. doi: 10.1016/j.molmed.2019.06.008. Epub 2019 Jul 17. Review.

4.

MicroRNAs as Companion Biomarkers for the Diagnosis and Prognosis of Acute Coronary Syndromes.

Condorelli G, van Rooij E.

Circ Res. 2019 Jul 19;125(3):341-342. doi: 10.1161/CIRCRESAHA.119.315455. Epub 2019 Jul 18. No abstract available.

PMID:
31318646
5.

Keeping the Heart Fitm2 during Chemotherapy.

Eding JEC, van Rooij E.

Mol Ther. 2019 Jan 2;27(1):10-12. doi: 10.1016/j.ymthe.2018.12.002. Epub 2018 Dec 11. No abstract available.

6.

Profiling proliferative cells and their progeny in damaged murine hearts.

Kretzschmar K, Post Y, Bannier-Hélaouët M, Mattiotti A, Drost J, Basak O, Li VSW, van den Born M, Gunst QD, Versteeg D, Kooijman L, van der Elst S, van Es JH, van Rooij E, van den Hoff MJB, Clevers H.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12245-E12254. doi: 10.1073/pnas.1805829115. Epub 2018 Dec 7.

7.

Single-Cell Sequencing of the Mammalian Heart.

Molenaar B, van Rooij E.

Circ Res. 2018 Oct 12;123(9):1033-1035. doi: 10.1161/CIRCRESAHA.118.313531. No abstract available.

PMID:
30355162
8.

Controlled Release of RNAi Molecules by Tunable Supramolecular Hydrogel Carriers.

Bakker MH, van Rooij E, Dankers PYW.

Chem Asian J. 2018 Nov 16;13(22):3501-3508. doi: 10.1002/asia.201800582. Epub 2018 Jun 25.

PMID:
29858562
9.

Case series: periocular habronemiasis in five horses in the Netherlands.

Verhaar N, Hermans H, van Rooij E, van Oldruitenborgh-Oosterbaan MS, Ensink J.

Vet Rec. 2018 Jun 30;182(26):746. doi: 10.1136/vr.104265. Epub 2018 Apr 25.

PMID:
29695450
10.

Dr Jyoti Patel, ESC Scientist of Tomorrow, interviews Dr Eva Van Rooij.

Patel J, van Rooij E.

Cardiovasc Res. 2018 Mar 1;114(3):e23-e24. doi: 10.1093/cvr/cvy024. No abstract available.

PMID:
29481650
11.

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation.

Gladka MM, Molenaar B, de Ruiter H, van der Elst S, Tsui H, Versteeg D, Lacraz GPA, Huibers MMH, van Oudenaarden A, van Rooij E.

Circulation. 2018 Jul 10;138(2):166-180. doi: 10.1161/CIRCULATIONAHA.117.030742. Epub 2018 Jan 31.

PMID:
29386203
12.

Postnatal Cardiac Gene Editing Using CRISPR/Cas9 With AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption.

Johansen AK, Molenaar B, Versteeg D, Leitoguinho AR, Demkes C, Spanjaard B, de Ruiter H, Akbari Moqadam F, Kooijman L, Zentilin L, Giacca M, van Rooij E.

Circ Res. 2017 Oct 27;121(10):1168-1181. doi: 10.1161/CIRCRESAHA.116.310370. Epub 2017 Aug 29.

PMID:
28851809
13.

MicroRNA-146a as a Regulator of Cardiac Energy Metabolism.

Demkes CJ, van Rooij E.

Circulation. 2017 Aug 22;136(8):762-764. doi: 10.1161/CIRCULATIONAHA.117.029703. No abstract available.

PMID:
28827220
14.

Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury.

Lacraz GPA, Junker JP, Gladka MM, Molenaar B, Scholman KT, Vigil-Garcia M, Versteeg D, de Ruiter H, Vermunt MW, Creyghton MP, Huibers MMH, de Jonge N, van Oudenaarden A, van Rooij E.

Circulation. 2017 Oct 10;136(15):1396-1409. doi: 10.1161/CIRCULATIONAHA.117.027832. Epub 2017 Jul 19.

PMID:
28724751
15.

The Efficacy of Cardiac Anti-miR-208a Therapy Is Stress Dependent.

Eding JE, Demkes CJ, Lynch JM, Seto AG, Montgomery RL, Semus HM, Jackson AL, Isabelle M, Chimenti S, van Rooij E.

Mol Ther. 2017 Mar 1;25(3):694-704. doi: 10.1016/j.ymthe.2017.01.012. Epub 2017 Feb 12.

16.

Genetics and Genomics of Single-Gene Cardiovascular Diseases: Common Hereditary Cardiomyopathies as Prototypes of Single-Gene Disorders.

Marian AJ, van Rooij E, Roberts R.

J Am Coll Cardiol. 2016 Dec 27;68(25):2831-2849. doi: 10.1016/j.jacc.2016.09.968. Review.

17.

Modulating microRNAs in cardiac surgery patients: Novel therapeutic opportunities?

Biglino G, Caputo M, Rajakaruna C, Angelini G, van Rooij E, Emanueli C.

Pharmacol Ther. 2017 Feb;170:192-204. doi: 10.1016/j.pharmthera.2016.11.004. Epub 2016 Nov 27. Review.

PMID:
27902930
18.

Introducing JACC: Basic to Translational Science: Why Now?

Mann DL, Annex BH, Bishopric NH, Force T, Kelly DP, Libby P, Roberts R, van Rooij E, Tomaselli G, Newby LK.

JACC Basic Transl Sci. 2016 Feb 15;1(1-2):1-2. doi: 10.1016/j.jacbts.2016.01.001. eCollection 2016 Jan-Feb. No abstract available.

19.

Extra-pair paternity in the long-tailed finch Poephila acuticauda.

van Rooij EP, Rollins LA, Holleley CE, Griffith SC.

PeerJ. 2016 Jan 5;4:e1550. doi: 10.7717/peerj.1550. eCollection 2016.

20.

Cardiac Repair after Myocardial Infarction.

van Rooij E.

N Engl J Med. 2016 Jan 7;374(1):85-7. doi: 10.1056/NEJMcibr1512011. No abstract available.

PMID:
26735998
21.

Function and Therapeutic Potential of Noncoding RNAs in Cardiac Fibrosis.

Creemers EE, van Rooij E.

Circ Res. 2016 Jan 8;118(1):108-18. doi: 10.1161/CIRCRESAHA.115.305242. Epub 2015 Nov 4. Review.

PMID:
26538569
22.

AntimiR-34a to Enhance Cardiac Repair After Ischemic Injury.

Gladka MM, van Rooij E.

Circ Res. 2015 Aug 14;117(5):395-7. doi: 10.1161/CIRCRESAHA.115.307066. No abstract available.

PMID:
26271535
23.

The role of microRNA in nutritional control.

Nolte-'t Hoen EN, Van Rooij E, Bushell M, Zhang CY, Dashwood RH, James WP, Harris C, Baltimore D.

J Intern Med. 2015 Aug;278(2):99-109. doi: 10.1111/joim.12372. Epub 2015 May 19.

24.

Song trait similarity in great tits varies with social structure.

Snijders L, van der Eijk J, van Rooij EP, de Goede P, van Oers K, Naguib M.

PLoS One. 2015 Feb 18;10(2):e0116881. doi: 10.1371/journal.pone.0116881. eCollection 2015.

25.

Exosomal microRNA clusters are important for the therapeutic effect of cardiac progenitor cells.

Sluijter JP, van Rooij E.

Circ Res. 2015 Jan 16;116(2):219-21. doi: 10.1161/CIRCRESAHA.114.305673. No abstract available.

PMID:
25593269
26.

MicroRNA mimicry blocks pulmonary fibrosis.

Montgomery RL, Yu G, Latimer PA, Stack C, Robinson K, Dalby CM, Kaminski N, van Rooij E.

EMBO Mol Med. 2014 Oct;6(10):1347-56. doi: 10.15252/emmm.201303604.

27.

miR-25 in heart failure.

Bush EW, van Rooij E.

Circ Res. 2014 Sep 12;115(7):610-2. doi: 10.1161/CIRCRESAHA.114.304909. No abstract available.

PMID:
25214573
28.

Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury.

Daniel JM, Penzkofer D, Teske R, Dutzmann J, Koch A, Bielenberg W, Bonauer A, Boon RA, Fischer A, Bauersachs J, van Rooij E, Dimmeler S, Sedding DG.

Cardiovasc Res. 2014 Sep 1;103(4):564-72. doi: 10.1093/cvr/cvu162. Epub 2014 Jun 27.

29.

Transient but not genetic loss of miR-451 is protective in the development of pulmonary arterial hypertension.

Grant JS, Morecroft I, Dempsie Y, van Rooij E, MacLean MR, Baker AH.

Pulm Circ. 2013 Dec;3(4):840-50. doi: 10.1086/674751.

30.

Development of microRNA therapeutics is coming of age.

van Rooij E, Kauppinen S.

EMBO Mol Med. 2014 Jul;6(7):851-64. doi: 10.15252/emmm.201100899. Review.

31.

MicroRNA-24 antagonism prevents renal ischemia reperfusion injury.

Lorenzen JM, Kaucsar T, Schauerte C, Schmitt R, Rong S, Hübner A, Scherf K, Fiedler J, Martino F, Kumarswamy R, Kölling M, Sörensen I, Hinz H, Heineke J, van Rooij E, Haller H, Thum T.

J Am Soc Nephrol. 2014 Dec;25(12):2717-29. doi: 10.1681/ASN.2013121329. Epub 2014 May 22.

32.

Endothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3 axis.

White K, Dempsie Y, Caruso P, Wallace E, McDonald RA, Stevens H, Hatley ME, Van Rooij E, Morrell NW, MacLean MR, Baker AH.

Hypertension. 2014 Jul;64(1):185-94. doi: 10.1161/HYPERTENSIONAHA.113.03037. Epub 2014 Apr 14.

PMID:
24732886
33.

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.

Hohl M, Ardehali H, Azuaje FJ, Breckenridge RA, Doehner W, Eaton P, Ehret GB, Fujita T, Gaetani R, Giacca M, Hasenfuß G, Heymans S, Leite-Moreira AF, Linke WA, Linz D, Lyon A, Mamas MA, Orešič M, Papp Z, Pedrazzini T, Piepoli M, Prosser B, Rizzuto R, Tarone G, Tian R, van Craenenbroeck E, van Rooij E, Wai T, Weiss G, Maack C.

Eur J Heart Fail. 2014 Jan;16(1):6-14. doi: 10.1002/ejhf.10. Epub 2013 Dec 14. Review. No abstract available.

34.

Synchronised provisioning at the nest: parental coordination over care in a socially monogamous species.

van Rooij EP, Griffith SC.

PeerJ. 2013 Dec 19;1:e232. doi: 10.7717/peerj.232. eCollection 2013 Dec 19.

35.

MicroRNA-214 antagonism protects against renal fibrosis.

Denby L, Ramdas V, Lu R, Conway BR, Grant JS, Dickinson B, Aurora AB, McClure JD, Kipgen D, Delles C, van Rooij E, Baker AH.

J Am Soc Nephrol. 2014 Jan;25(1):65-80. doi: 10.1681/ASN.2013010072. Epub 2013 Oct 24.

36.

Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model.

Hinkel R, Penzkofer D, Zühlke S, Fischer A, Husada W, Xu QF, Baloch E, van Rooij E, Zeiher AM, Kupatt C, Dimmeler S.

Circulation. 2013 Sep 3;128(10):1066-75. doi: 10.1161/CIRCULATIONAHA.113.001904. Epub 2013 Jul 29.

PMID:
23897866
37.

miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation.

McDonald RA, White KM, Wu J, Cooley BC, Robertson KE, Halliday CA, McClure JD, Francis S, Lu R, Kennedy S, George SJ, Wan S, van Rooij E, Baker AH.

Eur Heart J. 2013 Jun;34(22):1636-43. doi: 10.1093/eurheartj/eht105. Epub 2013 Mar 25.

38.

miRNA overexpression induces cardiomyocyte proliferation in vivo.

Baker AH, van Rooij E.

Mol Ther. 2013 Mar;21(3):497-8. doi: 10.1038/mt.2013.20. No abstract available.

39.

Plasma microRNAs serve as biomarkers of therapeutic efficacy and disease progression in hypertension-induced heart failure.

Dickinson BA, Semus HM, Montgomery RL, Stack C, Latimer PA, Lewton SM, Lynch JM, Hullinger TG, Seto AG, van Rooij E.

Eur J Heart Fail. 2013 Jun;15(6):650-9. doi: 10.1093/eurjhf/hft018. Epub 2013 Feb 6.

40.

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles.

van Rooij E, Olson EN.

Nat Rev Drug Discov. 2012 Nov;11(11):860-72. doi: 10.1038/nrd3864. Epub 2012 Oct 19. Review.

PMID:
23080337
41.

A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples.

Caruso P, Dempsie Y, Stevens HC, McDonald RA, Long L, Lu R, White K, Mair KM, McClure JD, Southwood M, Upton P, Xin M, van Rooij E, Olson EN, Morrell NW, MacLean MR, Baker AH.

Circ Res. 2012 Jul 20;111(3):290-300. doi: 10.1161/CIRCRESAHA.112.267591. Epub 2012 Jun 19.

PMID:
22715469
42.

A cardiac microRNA governs systemic energy homeostasis by regulation of MED13.

Grueter CE, van Rooij E, Johnson BA, DeLeon SM, Sutherland LB, Qi X, Gautron L, Elmquist JK, Bassel-Duby R, Olson EN.

Cell. 2012 Apr 27;149(3):671-83. doi: 10.1016/j.cell.2012.03.029.

43.

Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease.

Russell JL, Goetsch SC, Aguilar HR, Coe H, Luo X, Liu N, van Rooij E, Frantz DE, Schneider JW.

ACS Chem Biol. 2012 Jun 15;7(6):1077-83. doi: 10.1021/cb300001m. Epub 2012 May 9.

44.

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death.

Aurora AB, Mahmoud AI, Luo X, Johnson BA, van Rooij E, Matsuzaki S, Humphries KM, Hill JA, Bassel-Duby R, Sadek HA, Olson EN.

J Clin Invest. 2012 Apr;122(4):1222-32. doi: 10.1172/JCI59327. Epub 2012 Mar 19.

45.

Developing microRNA therapeutics.

van Rooij E, Purcell AL, Levin AA.

Circ Res. 2012 Feb 3;110(3):496-507. doi: 10.1161/CIRCRESAHA.111.247916. Review.

PMID:
22302756
46.

Introduction to the series on microRNAs in the cardiovascular system.

van Rooij E.

Circ Res. 2012 Feb 3;110(3):481-2. doi: 10.1161/CIRCRESAHA.111.257311. Review.

PMID:
22302754
47.

Circulating microRNAs to identify human heart failure.

Seto AG, van Rooij E.

Eur J Heart Fail. 2012 Feb;14(2):118-9. doi: 10.1093/eurjhf/hfr179. No abstract available.

48.

Inhibition of miR-15 protects against cardiac ischemic injury.

Hullinger TG, Montgomery RL, Seto AG, Dickinson BA, Semus HM, Lynch JM, Dalby CM, Robinson K, Stack C, Latimer PA, Hare JM, Olson EN, van Rooij E.

Circ Res. 2012 Jan 6;110(1):71-81. doi: 10.1161/CIRCRESAHA.111.244442. Epub 2011 Nov 3.

49.

Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure.

Montgomery RL, Hullinger TG, Semus HM, Dickinson BA, Seto AG, Lynch JM, Stack C, Latimer PA, Olson EN, van Rooij E.

Circulation. 2011 Oct 4;124(14):1537-47. doi: 10.1161/CIRCULATIONAHA.111.030932. Epub 2011 Sep 6.

50.

MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes.

Porrello ER, Johnson BA, Aurora AB, Simpson E, Nam YJ, Matkovich SJ, Dorn GW 2nd, van Rooij E, Olson EN.

Circ Res. 2011 Sep 2;109(6):670-9. doi: 10.1161/CIRCRESAHA.111.248880. Epub 2011 Jul 21.

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