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Items: 31


Draft Genome Sequence of Aryl Hydrocarbon Receptor Activator Strains Lactobacillus reuteri R2lc and 2010.

Özçam M, van Pijkeren JP.

Microbiol Resour Announc. 2019 Apr 4;8(14). pii: e00067-19. doi: 10.1128/MRA.00067-19.


Exploiting Prophage-Mediated Lysis for Biotherapeutic Release by Lactobacillus reuteri.

Alexander LM, Oh JH, Stapleton DS, Schueler KL, Keller MP, Attie AD, van Pijkeren JP.

Appl Environ Microbiol. 2019 May 2;85(10). pii: e02335-18. doi: 10.1128/AEM.02335-18. Print 2019 May 15.


Dietary Fructose and Microbiota-Derived Short-Chain Fatty Acids Promote Bacteriophage Production in the Gut Symbiont Lactobacillus reuteri.

Oh JH, Alexander LM, Pan M, Schueler KL, Keller MP, Attie AD, Walter J, van Pijkeren JP.

Cell Host Microbe. 2019 Feb 13;25(2):273-284.e6. doi: 10.1016/j.chom.2018.11.016. Epub 2019 Jan 15.


Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice.

Hendrikx T, Duan Y, Wang Y, Oh JH, Alexander LM, Huang W, Stärkel P, Ho SB, Gao B, Fiehn O, Emond P, Sokol H, van Pijkeren JP, Schnabl B.

Gut. 2019 Aug;68(8):1504-1515. doi: 10.1136/gutjnl-2018-317232. Epub 2018 Nov 17.


Gut Symbionts Lactobacillus reuteri R2lc and 2010 Encode a Polyketide Synthase Cluster That Activates the Mammalian Aryl Hydrocarbon Receptor.

Özçam M, Tocmo R, Oh JH, Afrazi A, Mezrich JD, Roos S, Claesen J, van Pijkeren JP.

Appl Environ Microbiol. 2019 May 2;85(10). pii: e01661-18. doi: 10.1128/AEM.01661-18. Print 2019 May 15.


Genome alterations associated with improved transformation efficiency in Lactobacillus reuteri.

Ortiz-Velez L, Ortiz-Villalobos J, Schulman A, Oh JH, van Pijkeren JP, Britton RA.

Microb Cell Fact. 2018 Sep 3;17(1):138. doi: 10.1186/s12934-018-0986-8.


d-Alanyl-d-Alanine Ligase as a Broad-Host-Range Counterselection Marker in Vancomycin-Resistant Lactic Acid Bacteria.

Zhang S, Oh JH, Alexander LM, Özçam M, van Pijkeren JP.

J Bacteriol. 2018 Jun 11;200(13). pii: e00607-17. doi: 10.1128/JB.00607-17. Print 2018 Jul 1.


Identification of probiotic effector molecules: present state and future perspectives.

Lebeer S, Bron PA, Marco ML, Van Pijkeren JP, O'Connell Motherway M, Hill C, Pot B, Roos S, Klaenhammer T.

Curr Opin Biotechnol. 2018 Feb;49:217-223. doi: 10.1016/j.copbio.2017.10.007. Epub 2017 Nov 16. Review.


Genome Editing of Food-Grade Lactobacilli To Develop Therapeutic Probiotics.

van Pijkeren JP, Barrangou R.

Microbiol Spectr. 2017 Sep;5(5). doi: 10.1128/microbiolspec.BAD-0013-2016. Review.


Exploiting CRISPR-Cas immune systems for genome editing in bacteria.

Barrangou R, van Pijkeren JP.

Curr Opin Biotechnol. 2016 Feb;37:61-68. doi: 10.1016/j.copbio.2015.10.003. Epub 2015 Nov 26. Review.


Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice.

Chen P, Torralba M, Tan J, Embree M, Zengler K, Stärkel P, van Pijkeren JP, DePew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B.

Gastroenterology. 2015 Jan;148(1):203-214.e16. doi: 10.1053/j.gastro.2014.09.014. Epub 2014 Sep 16.


Precision genome engineering in lactic acid bacteria.

van Pijkeren JP, Britton RA.

Microb Cell Fact. 2014 Aug 29;13 Suppl 1:S10. doi: 10.1186/1475-2859-13-S1-S10. Epub 2014 Aug 29. Review.


CRISPR-Cas9-assisted recombineering in Lactobacillus reuteri.

Oh JH, van Pijkeren JP.

Nucleic Acids Res. 2014;42(17):e131. doi: 10.1093/nar/gku623. Epub 2014 Jul 29.


Bacterial systems for gene delivery to systemic tumors.

Cummins J, Cronin M, van Pijkeren JP, Gahan CG, Tangney M.

Methods Mol Biol. 2014;1141:201-9. doi: 10.1007/978-1-4939-0363-4_13.


Role of Lactobacillus reuteri cell and mucus-binding protein A (CmbA) in adhesion to intestinal epithelial cells and mucus in vitro.

Jensen H, Roos S, Jonsson H, Rud I, Grimmer S, van Pijkeren JP, Britton RA, Axelsson L.

Microbiology. 2014 Apr;160(Pt 4):671-81. doi: 10.1099/mic.0.073551-0. Epub 2014 Jan 28.


The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization.

Stockdale SR, Mahony J, Courtin P, Chapot-Chartier MP, van Pijkeren JP, Britton RA, Neve H, Heller KJ, Aideh B, Vogensen FK, van Sinderen D.

J Biol Chem. 2013 Feb 22;288(8):5581-90. doi: 10.1074/jbc.M112.444901. Epub 2013 Jan 8.


Control and augmentation of long-term plasmid transgene expression in vivo in murine muscle tissue and ex vivo in patient mesenchymal tissue.

Morrissey D, van Pijkeren JP, Rajendran S, Collins SA, Casey G, O'Sullivan GC, Tangney M.

J Biomed Biotechnol. 2012;2012:379845. doi: 10.1155/2012/379845. Epub 2012 Jul 1.


Exploring optimization parameters to increase ssDNA recombineering in Lactococcus lactis and Lactobacillus reuteri.

Van Pijkeren JP, Neoh KM, Sirias D, Findley AS, Britton RA.

Bioengineered. 2012 Jul-Aug;3(4):209-17. doi: 10.4161/bioe.21049. Epub 2012 Jul 1.


Fibrinogen-binding and platelet-aggregation activities of a Lactobacillus salivarius septicaemia isolate are mediated by a novel fibrinogen-binding protein.

Collins J, van Pijkeren JP, Svensson L, Claesson MJ, Sturme M, Li Y, Cooney JC, van Sinderen D, Walker AW, Parkhill J, Shannon O, O'Toole PW.

Mol Microbiol. 2012 Sep;85(5):862-77. doi: 10.1111/j.1365-2958.2012.08148.x. Epub 2012 Jul 11.


Glycerol supplementation enhances L. reuteri's protective effect against S. Typhimurium colonization in a 3-D model of colonic epithelium.

De Weirdt R, Crabbé A, Roos S, Vollenweider S, Lacroix C, van Pijkeren JP, Britton RA, Sarker S, Van de Wiele T, Nickerson CA.

PLoS One. 2012;7(5):e37116. doi: 10.1371/journal.pone.0037116. Epub 2012 May 31.


Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling.

Thomas CM, Hong T, van Pijkeren JP, Hemarajata P, Trinh DV, Hu W, Britton RA, Kalkum M, Versalovic J.

PLoS One. 2012;7(2):e31951. doi: 10.1371/journal.pone.0031951. Epub 2012 Feb 22.


High efficiency recombineering in lactic acid bacteria.

van Pijkeren JP, Britton RA.

Nucleic Acids Res. 2012 May;40(10):e76. doi: 10.1093/nar/gks147. Epub 2012 Feb 10.


Targeting of breast metastases using a viral gene vector with tumour-selective transcription.

Rajendran S, Collins S, van Pijkeren JP, O'Hanlon D, O'Sullivan GC, Tangney M.

Anticancer Res. 2011 May;31(5):1627-35.


The use of Listeria monocytogenes as a DNA delivery vector for cancer gene therapy.

Tangney M, van Pijkeren JP, Gahan CG.

Bioeng Bugs. 2010 Jul-Aug;1(4):284-7. doi: 10.4161/bbug.1.4.11725. Epub 2010 Mar 7.


A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy.

van Pijkeren JP, Morrissey D, Monk IR, Cronin M, Rajendran S, O'Sullivan GC, Gahan CG, Tangney M.

Hum Gene Ther. 2010 Apr;21(4):405-16. doi: 10.1089/hum.2009.022.


Lactobacillus salivarius modulates cytokine induction and virulence factor gene expression in Helicobacter pylori.

Ryan KA, O'Hara AM, van Pijkeren JP, Douillard FP, O'Toole PW.

J Med Microbiol. 2009 Aug;58(Pt 8):996-1005. doi: 10.1099/jmm.0.009407-0. Epub 2009 Jun 15.


Anti-metastatic effects of viral and non-viral mediated Nk4 delivery to tumours.

Buhles A, Collins SA, van Pijkeren JP, Rajendran S, Miles M, O'Sullivan GC, O'Hanlon DM, Tangney M.

Genet Vaccines Ther. 2009 Mar 9;7:5. doi: 10.1186/1479-0556-7-5.


Characterization of endogenous plasmids from Lactobacillus salivarius UCC118.

Fang F, Flynn S, Li Y, Claesson MJ, van Pijkeren JP, Collins JK, van Sinderen D, O'Toole PW.

Appl Environ Microbiol. 2008 May;74(10):3216-28. doi: 10.1128/AEM.02631-07. Epub 2008 Apr 4.


Distribution of megaplasmids in Lactobacillus salivarius and other lactobacilli.

Li Y, Canchaya C, Fang F, Raftis E, Ryan KA, van Pijkeren JP, van Sinderen D, O'Toole PW.

J Bacteriol. 2007 Sep;189(17):6128-39. Epub 2007 Jun 22.


Comparative and functional analysis of sortase-dependent proteins in the predicted secretome of Lactobacillus salivarius UCC118.

van Pijkeren JP, Canchaya C, Ryan KA, Li Y, Claesson MJ, Sheil B, Steidler L, O'Mahony L, Fitzgerald GF, van Sinderen D, O'Toole PW.

Appl Environ Microbiol. 2006 Jun;72(6):4143-53.


Multireplicon genome architecture of Lactobacillus salivarius.

Claesson MJ, Li Y, Leahy S, Canchaya C, van Pijkeren JP, Cerdeño-Tárraga AM, Parkhill J, Flynn S, O'Sullivan GC, Collins JK, Higgins D, Shanahan F, Fitzgerald GF, van Sinderen D, O'Toole PW.

Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6718-23. Epub 2006 Apr 14.

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