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Items: 12

1.

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia.

van Oosterwijk JG, Buelow DR, Drenberg CD, Vasilyeva A, Li L, Shi L, Wang YD, Finkelstein D, Shurtleff SA, Janke LJ, Pounds S, Rubnitz JE, Inaba H, Pabla N, Baker SD.

J Clin Invest. 2018 Jan 2;128(1):369-380. doi: 10.1172/JCI91893. Epub 2017 Dec 11.

2.

Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice.

van Oosterwijk JG, Li C, Yang X, Opferman JT, Sherr CJ.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):7420-7425. doi: 10.1073/pnas.1707292114. Epub 2017 Jun 26.

3.

Targeting survivin as a potential new treatment for chondrosarcoma of bone.

de Jong Y, van Oosterwijk JG, Kruisselbrink AB, Briaire-de Bruijn IH, Agrogiannis G, Baranski Z, Cleven AH, Cleton-Jansen AM, van de Water B, Danen EH, Bovée JV.

Oncogenesis. 2016 May 9;5:e222. doi: 10.1038/oncsis.2016.33.

4.

An orthotopic mouse model for chondrosarcoma of bone provides an in vivo tool for drug testing.

van Oosterwijk JG, Plass JR, Meijer D, Que I, Karperien M, Bovée JV.

Virchows Arch. 2015 Jan;466(1):101-9. doi: 10.1007/s00428-014-1670-y. Epub 2014 Oct 21.

PMID:
25331842
5.

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma.

van Oosterwijk JG, Anninga JK, Gelderblom H, Cleton-Jansen AM, Bovée JV.

Hematol Oncol Clin North Am. 2013 Oct;27(5):1021-48. doi: 10.1016/j.hoc.2013.07.012. Epub 2013 Aug 26. Review.

PMID:
24093174
6.

Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.

van Oosterwijk JG, van Ruler MA, Briaire-de Bruijn IH, Herpers B, Gelderblom H, van de Water B, Bovée JV.

Br J Cancer. 2013 Sep 3;109(5):1214-22. doi: 10.1038/bjc.2013.451. Epub 2013 Aug 6.

7.

Functional profiling of receptor tyrosine kinases and downstream signaling in human chondrosarcomas identifies pathways for rational targeted therapy.

Zhang YX, van Oosterwijk JG, Sicinska E, Moss S, Remillard SP, van Wezel T, Bühnemann C, Hassan AB, Demetri GD, Bovée JV, Wagner AJ.

Clin Cancer Res. 2013 Jul 15;19(14):3796-807. doi: 10.1158/1078-0432.CCR-12-3647. Epub 2013 May 28.

8.

Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.

van Oosterwijk JG, Meijer D, van Ruler MA, van den Akker BE, Oosting J, Krenács T, Picci P, Flanagan AM, Liegl-Atzwanger B, Leithner A, Athanasou N, Daugaard S, Hogendoorn PC, Bovée JV.

Am J Pathol. 2013 Apr;182(4):1347-56. doi: 10.1016/j.ajpath.2012.12.036. Epub 2013 Feb 15.

PMID:
23415961
9.

Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone.

van Oosterwijk JG, de Jong D, van Ruler MA, Hogendoorn PC, Dijkstra PD, van Rijswijk CS, Machado I, Llombart-Bosch A, Szuhai K, Bovée JV.

BMC Cancer. 2012 Aug 28;12:375. doi: 10.1186/1471-2407-12-375.

10.

Cartilage tumour progression is characterized by an increased expression of heparan sulphate 6O-sulphation-modifying enzymes.

Waaijer CJ, de Andrea CE, Hamilton A, van Oosterwijk JG, Stringer SE, Bovée JV.

Virchows Arch. 2012 Oct;461(4):475-81. doi: 10.1007/s00428-012-1300-5. Epub 2012 Aug 18.

PMID:
22903264
11.

Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance.

van Oosterwijk JG, Herpers B, Meijer D, Briaire-de Bruijn IH, Cleton-Jansen AM, Gelderblom H, van de Water B, Bovée JV.

Ann Oncol. 2012 Jun;23(6):1617-26. doi: 10.1093/annonc/mdr512. Epub 2011 Nov 23.

PMID:
22112972
12.

Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.

Pansuriya TC, van Eijk R, d'Adamo P, van Ruler MA, Kuijjer ML, Oosting J, Cleton-Jansen AM, van Oosterwijk JG, Verbeke SL, Meijer D, van Wezel T, Nord KH, Sangiorgi L, Toker B, Liegl-Atzwanger B, San-Julian M, Sciot R, Limaye N, Kindblom LG, Daugaard S, Godfraind C, Boon LM, Vikkula M, Kurek KC, Szuhai K, French PJ, Bovée JV.

Nat Genet. 2011 Nov 6;43(12):1256-61. doi: 10.1038/ng.1004.

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